Ventilator-Induced Lung Injury

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Narrative Reviews

Ventilator-Induced Lung Injury

Image: Shutterstock / Medical-R

Sections

General | Investigations & Monitoring | Therapies

General

General

Zhang. Research progress on the pathogenesis and treatment of ventilator-induced diaphragm dysfunction. Heliyon 2023;9(11):e22317
Madahar. Emerging concepts in ventilation-induced lung injury. F1000Res 2020;9:F1000 Faculty Rev-222

Neonates

Kalikkot Thekkeveedu. Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies. J Clin Med 2022;11(3):557

Background

Pathophysiology

Gaver. The POOR Get POORer: A Hypothesis for the Pathogenesis of Ventilator-induced Lung Injury. Am J Respir Crit Care Med 2020;202(8):1081-1087

Mechanical Power

Conditions

P-SILI

Marongiu. Clinical and Experimental Evidence for Patient Self-Inflicted Lung Injury (P-SILI) and Bedside Monitoring. J Clin Med 2024;13:4018

COVID-19

Habashi. Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications. J Appl Physiol 2021;130(3):877-891

Manual VILI

White. Pathophysiology and Prevention of Manual-Ventilation-Induced Lung Injury (MVILI). Pathophysiology 2024;31:583-595

Complications

Oxygen Toxicity

Hochberg. Oxygen Toxicity in Critically Ill Adults. Am J Respir Crit Care Med 2021;204(6):632-641

Patient-Ventilator Dyssynchrony

Mirabella. Patient-Ventilator Asynchronies: Clinical Implications and Practical Solutions. Respir Care 2020;65(11):1751-1766

Ventilator-Induced Diaphragmatic Dysfunction

Le Stang. Critical illness-associated limb and diaphragmatic weakness. Curr Opin Crit Care 2024;epublished March 5th

Cognitive Impairment

Liu. Future directions in ventilator-induced lung injury associated cognitive impairment: a new sight. Front Physiol 2023;14:1308252

Monitoring & Investigations

Ultrasound

Bellissimo. Measuring Diaphragm Thickness and Function Using Point-of-Care Ultrasound. J Vis Exp 2023:(201)

Therapies

Ultra-Lung Protective Ventilation

Abrams. Risks and Benefits of Ultra–Lung-Protective Invasive Mechanical Ventilation Strategies with a Focus on Extracorporeal Support. Am J Respir Crit Care Med 2022;205(8):873–882

Phrenic Nerve Stimulation

Panelli. Phrenic nerve stimulation to prevent diaphragmatic dysfunction and ventilator-induced lung injury. ICMx 2023;11:94