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Critical Care Reviews Meeting

The best critical care trials in the world

Presentations

Trial Results:  BLING III  |  PROTECTION  |  CYCLE  |  PREOXI  |  HEMOTION  |  DEFENDER  |  NAVIGATE  |  REVISE 

IPDMA Results:  Intensive Glucose Control

Trial Reviews:  NICO  |  TGC-FAST  |  REMAP-CAP Statins for COVID-19

Other Talks:  Integrating Trials into Clinical Practice  |  John Hinds Lecture

BLING III

Jeff Lipman, Dorrilyn Rajbhandari, Joel Dulhunty & Mohd (Hafiz) Abdul-Aziz present the results of the BLING III trial and associated systematic review and meta analysis at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

BLING III compared continuous with intermittent beta lactam antibiotic administration in critically ill patients with sepsis.

BLING III Paper
SRMA

Interview with the Trialists

PROTECTION

Giovanni Landoni and Martina Baiardo Redaelli present the results of the PROTECTION trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

PROTECTION investigates the efficacy of amino acid infusion post cardiac surgery for the prevention of acute kidney injury.

Adam Deane delivers an independent editorial and Lennie Derde chairs a panel discussion amongst Charuhas Thakar, David Harrison, Stephen Webb and Kathy Rowan.

PROTECTION was simultaneously published in the New England Journal of Medicine.

PROTECTION Paper

Interview with the Trialists

CYCLE

Michelle Kho and Heather O'Grady present the results of the CYCLE trial at the Critical Care Reviews Meeting 2024. CYCLE investigates the use of in-bed ergometry in the critically ill mechanically ventilated patient.

The session is chaired by Marion Campbell. Panellists include Andrew Althouse, Carol Hodgson, Kevin Gibbs and Paul Mouncey.

CYCLE was simultaneously published in NEJM Evidence.

CYCLE Paper
Meta Analysis

Interview with the Trialists

PREOXI

Jonathan Casey and Kevin Gibbs present the results of the PRE-OXI trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast. PRE-OXI investigated non-invasive ventilation for preoxygenation in emergency intubation in the critically ill.

Yonathan Freund delivers an independent editorial. Catriona Kelly chairs a panel discussion with Anthony Gordon, Sheila Myatra, Victoria Cornelius and Jan Gunst.

PRE-OXI was simultaneously published in the New England Journal of Medicine.

PREOXI Paper

Interview with the Trialists

HEMOTION

Alexis Turgeon and Francois Lauzier (both Quebec City) present the results of the HEMOTION trial at the Critical Care Reviews Meeting 2024 in Titanic Belfast. HEMOTION compared liberal with restrictive transfusion thresholds in critically ill patients with traumatic brain injury.

The session is chaired by Catriona Kelly (Dublin). John Myburgh (Sydney) delivers an independent editorial. Anthony Gordon (London), Marion Campbell (Aberdeen), Alistair Nichol (Dublin) and Carol Hodgson (Melbourne) contribute to a panel discussion.

HEMOTION was simultaneously published in the New England Journal of Medicine.

HEMOTION Paper

Interview with the Trialists

DEFENDER

Profs Caio Tavares and Fernando Zampieri present the results of the DEFENDER trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

DEFENDER investigated the efficacy of dapagliflozin in the critically ill.

Danny McAuley delivers an independent editorial and Christopher Seymour chairs a panel discussion between Simon Finfer, Lennie Derde, Marion Campbell and Catherine McKenzie.

DEFENDER was simultaneously published in JAMA.

DEFENDER Paper

Interview with the Trialists

REVISE

Deborah Cook and Adam Deane present the results of the REVISE trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

REVISE investigates the efficacy of stress ulcer prophylaxis with pantoprazole in critically ill mechanically ventilated patients.

Kathy Rowan delivers an editorial and Darren Taichman chairs a panel discussion between David Harrison, Martina Baiardo Redaelli, Madiha Hasmi and Danny McAuley.

REVISE was simultaneously published in the New England Journal of Medicine.

REVISE Paper
SRMA

Interview with the Trialists

Intensive Glucose Control

Simon Finfer (Sydney) and Derick Adigbli (Melbourne) present the results of an IPDMA of intensive glucose control in the critically ill at the Critical Care Reviews Meeting 2024. Lennie Derde (Utrecht) delivers an independent editorial. Danny McAuley (Belfast) chairs the session.

This IPDMA was simultaneously published in NEJM Evidence.

IPDMA Paper

Interview with the Trialists

NICO

Yonathan Freund (Paris) presents the NICO trial at the Critical Care Reviews Meeting 2024 in Titanic Belfast. Sheila Myatra (Mumbai) delivers an independent editorial. The session is chaired by Danny McAuley (Belfast).

The NICO trial investigated non-invasive airway management of patients comatose from acute poisoning.

NICO was previously published in JAMA.

NICO Paper

TGC-FAST

Jan Gunst (Leuven) presents the TGC-FAST trial at the Critical Care Reviews Meeting 2024. Lennie Derde delivers an independent editorial. The session is chaired by Danny McAuley (Belfast).

TGC-FAST was published in the New England Journal of Medicine.

TGC-FAST Paper

REMAP-CAP Statins for COVID-19

Tom Hills presents the statin domain of the REMAP-CAP platform trial at CCR24. Peter McGuigan gives an editorial on the trial. Bronwen Connolly chairs the session.

This trial was published in the New England Journal of Medicine.

Statins Paper

Integrating Trials into Clinical Practice

Prof Kirsten Bibbins-Domingo talks about how clinical trials can be routinely integrated into clinical practice.

John Hinds Lecture

Professor Kathy Rowan delivers the 2024 John Hinds Lecture, entitled "ICNARC at 30 - Back to the Future".
Kathy Rowan delivering the John Hinds Lecture at CCR24

CCR24 has come and gone. We hosted an amazing 11 major trial result presentations and 3 systematic reviews and meta analyses presentations. Ten of these have been published across the New England Journal of Medicine, JAMA and NEJM Evidence.

We will start to add the edited recording of these talks, both in video and audio versions, to the website over the next couple of weeks. These will be free to view as usual.

Thanks to the trialists for travelling to Belfast to present their amazing trials, our wonderful faculty for their insightful discussions, our expert audience for their contributions, the major journals for facilitating the timings of the simultaneous publications, and our sponsors for supporting us:

  • Special Sponsors - Visit Belfast, Belfast City Council, Tourism NI, HSC R&D Division, the Belfast trust
  • Silver Sponsor - Fisher & Paykel Helathcare
  • Bronze Sponsors - Drager, EOLAS Medical, Gettinge, & Teleflex.

Opening Performance CCR24

Dr Akhil Krishnakumar plays the opening performance at the Critical Care Reviews Meeting 2024, on June 12th, at Titanic Belfast.

Programme

For those requiring the programmeto submit for CPD / CME purposes.

Long
Short