- Neuro
- Circulatory
- Airway
- Respiratory
- GI
- Liver
- Renal
- Sepsis & ID
- Trauma
- Paediatrics
- Perioperative
- Miscellaneous
- Hu. Endovascular treatment of medium-vessel-occlusion strokes. N Engl J Med 2026;394(19):1894-1904
- Xiong. Intravenous Tenecteplase Prior to Endovascular Treatment for Ischemic Stroke at 4.5 to 24 Hours. The TNK-PLUS Randomized Clinical Trial. JAMA 2026;epublished May 8th
- INSTANT Trial Authors for the INSTANT Investigators. Intravenous Tirofiban After Tenecteplase in Acute Ischemic StrokeThe INSTANT Randomized Clinical Trial. JAMA 2026;epublished May 8th
- Renú. Adjunctive intra-arterial alteplase after successful thrombectomy for acute ischemic stroke: the CHOICE-2 randomized clinical trial. JAMA 2026;epublished May 7th
- Wang. Ticagrelor with aspirin dual antiplatelet therapy combined with intravenous thrombolysis in patients with ischaemic stroke in China (TAPIS): a multicentre, double-blind, randomised controlled trial. Lancet 2026;407(10542):1919-1928
- Fischer. Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes of a multicentre, open-label, randomised trial. Lancet Neurol 2026;25(6):571-580
- Yang. Short-term light sedation with remimazolam besylate versus propofol in the ICU (SHOSREB): a multicentre, randomized, single-blind, controlled trial. Intensive Care Med 2026;epublished March 31st
- Sonneville. Restrictive vs Liberal Physical Restraint Strategies in Critically Ill Patients: The R2D2-ICU Randomized Clinical Trial. JAMA 2026;epublished March 17th
- Glinsky. Safety and efficacy of intensive task-specific training in people with recent spinal cord injury: a phase 3, pragmatic, randomised, assessor-blinded, superiority trial. Lancet Neurol 2026;25(3):234-244
- Ma. Tenecteplase for acute non–large vessel occlusion 4.5 to 24 hours after ischemic stroke: the OPTION randomized clinical trial. JAMA 2026;epublished February 5th
- Broderick. Recombinant factor VIIa versus placebo for spontaneous intracerebral haemorrhage within 2 h of symptom onset (FASTEST): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet 2026;epublished February 4th
- Xiong Y, Alemseged F, Cao Z, et al. Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial. Lancet. 2026;epublished February 5th
- Solomon. Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial. Lancet Neurol 2026;25(2):136-146
- Lu. Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial. Lancet 2026;epublished January 30th
- Litton. High-Flow Nasal Oxygen Therapy After Cardiac Surgery: A Randomized Clinical Trial. JAMA Netw Open 2026;9(4):e265447
- Yuan. Electrical impedance tomography-guided positive end-expiratory pressure and mortality of patients with the acute respiratory distress syndrome: the EITVent randomized clinical trial. Am J Respir Crit Care Med 2026;212(3):440-451
- Frat. High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure. N Engl J Med 2026;epublished March 17th
- Ornowska. 4% tetrasodium EDTA to prevent central venous access device–associated complications: a randomized clinical trial. JAMA 2026;epublished May 18th
- Hashmi. Ivermectin for critically and noncritically ill hospitalized patients with COVID-19: randomized, embedded, multifactorial adaptive platform trial for community-acquired pneumonia (REMAP-CAP). Crit Care Med 2026;epublished May 8th
- Banerjee. Fast Antimicrobial Susceptibility Testing for Gram-Negative Bacteremia. The FAST Randomized Clinical Trial. JAMA 2026;epublished April 18th
- Neyra. Polymyxin B haemoadsorption in endotoxic septic shock (Tigris): a multicentre, open-label, Bayesian, randomised, controlled, phase 3 trial. Lancet Respir Med 2026;epublished March 23rd
- Todd. Procalcitonin testing combined with NEWS2 evaluation compared with usual care based on NEWS2 for identification of sepsis and antibiotic initiation in the emergency department in England and Wales (PRONTO): a multicentre, randomised, controlled, open-label, phase 3 trial. Lancet Respir Med 2026;epublished March 22nd
- Sakr. Albumin replacement therapy in septic shock: a randomized clinical trial. JAMA Netw Open 2026;9(2):e2559297
- Sperry. TOWAR Study Group. Prehospital resuscitation with type O whole blood for trauma and hemorrhage. N Engl J Med 2026;epublished May 18th
- Mohan. Using Serious Games to Increase the Implementation of Trauma Triage Guidelines. A Randomized Clinical Trial. JAMA 2026;epublished April 20th
- Smith. Prehospital Whole Blood in Traumatic Hemorrhage — a Randomized Controlled Trial. N Engl J Med 2026;epublished March 17th
- Louman. Oxygen saturation thresholds in children with acute respiratory distress (OxyKids): a multicentre, open, parallel-group, randomised clinical trial. Lancet Respir Med 2026;epublished May 12th
- Balamuth. Balanced fluid or 0.9% saline in children treated for septic shock. N Engl J Med 2026;epublished April 23rd
- Semple. Endotracheal surfactant for infants with life-threatening bronchiolitis (BESS): a randomised, blinded, sham-controlled, phase 2 trial. Lancet Respir Med 2026;epublished March 21st
Last updated May 22nd, 2026