Ary Serpa Neto, MD, MSc, PhD is an Intensivist and Director of Intensive Care Research at Austin Hospital in Melbourne, Australia. He is also an Associate Professor at the Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, where he leads the Mechanical Ventilation and Renal & Metabolic Programs. He is a founding member of the Protective Ventilation Network (PROVENet) and a member of the Scientific Committee of the Brazilian Research in Intensive Care Network (BRICNet). His research focuses on mechanical ventilation, renal and metabolic care, and advanced clinical trial methodology, with a strong emphasis on translating evidence into clinical practice.

Ary has authored over 430 publications, including multiple articles in The New England Journal of Medicine, JAMA, and The Lancet Respiratory Medicine, and his work has been cited in several international guidelines. He currently leads several large-scale international randomised clinical trials in Australia, including the NHMRC-funded SODa-BIC, DRIVE and GuARDS trials.

Brenda is a Professor in Physiotherapy at Ulster University in Northern Ireland. She leads research focused on the health and rehabilitation of people after critical Illness and people with respiratory conditions. She has expertise with a range of research methodologies and is involved in several multi-centre research programmes funded (each over £1million) by the NIHR.

Brenda is the lead for the Centre for Health and Rehabilitation Technologies (CHaRT) School of Health Sciences, Ulster University, completing research in collaboration with local hospitals, and national and international colleagues, and she has key roles in Northern Ireland (NI) research infrastructure e.g. Clinical Research Facility (NICRF) Management Group.

She is a member of several professional bodies that support advancing education and research in respiratory health and recovery after critical illness and is an Associate Editor for Physiotherapy Canada. She has successfully supervised PhD students, MSc students, and research staff (> 50) and published widely (h-index 21). Recent achievements include winner of the Advancing Healthcare Awards Northern Ireland: Award for Research and Development (2023) and was recent president of the International Confederation of Cardiorespiratory Physiotherapists (2019-2023), World Physiotherapy.

Danny McAuley is a Consultant and Professor in Intensive Care Medicine at the Regional Intensive Care Unit at the Royal Victoria Hospital and Queen’s University of Belfast. He undertook his training in Belfast, Birmingham, London and San Francisco. He is Programme Director for the MRC/NIHR Efficacy and Mechanism Evaluation (EME) programme and Co-Director of Research for the UK Intensive Care Society. He has several research interests including Acute Respiratory Distress Syndrome and clinical trials. He is involved in multiple clinical trials, including being an executive team member of the PANTHER trial, a Bayesian adaptive platform randomized clinical trial studying novel interventions to improve outcomes for patients with acute hypoxaemic respiratory failure. 

Twitter: @dfmcauley

Dr Arthur Kwizera is a Ugandan specialist in anaesthesia and intensive care, with advanced training from the University of British Columbia, Canada, and a fellowship in critical care interventional pulmonology from Pordenone, Italy. He has been an invited speaker at major international congresses, including the European Society of Intensive Care Medicine (ESICM), International Fluid Academy (IFAD), and the Society of Critical Care Medicine (SCCM). He is the first African recipient of honorary membership from ESICM, recognising his leadership in advancing critical care in low- and middle-income countries.

He is the founder and president of the Intensive Care Society of Uganda and a foundation fellow of the College of Anaesthesiologists of East, Central, and Southern Africa (CANECSA). He serves on global expert panels for the World Health Organisation (WHO), the Surviving Sepsis Campaign (SSC), the World Federation of Societies of Anaesthesiologists (WFSA), and, in the past, the USAID Technical Advisory Group on oxygen therapy.

Sander Rozemeijer is an anesthesiology resident at Amsterdam UMC in the Netherlands. After graduating medical school with honours in 2018, he started his doctoral program in the field of Intensive Care Medicine. His research focusses on the effects of vitamin C in ischemia-reperfusion injury. He coordinated the multicenter VITaCCA-trial, investigating the effect of early high-dose vitamin C in post-cardiac arrest patients.

Dr Angelique de Man is an intensivist at Amsterdam UMC in the Netherlands. She has extensive experience in clinical and, since she is also a medical biologist, also in translational research. Her domains of expertise in research comprise hyperoxia, cardiac arrest, vitamin C and micronutrients in critical care setting.

She coordinated the O2-ICU trial, investigating low-normal vs high-normal PaO2 target in 400 critically ill patients with SIRS (JAMA 2021). She was coauthor of the micronutrient guidelines (doi: 10.1016/j.clnu.2022.02.015) and is currently leader of the micronutrients working group of the ESICM. Furthermore, she is a member of the ESPEN special interest group for micronutrients. Together with her PhD-student Sander Rozemeijer, she coordinated the VITaCCA trial, an RCT investigating the effect of 2 different doses (3 and 10 g per day) of intravenously administered vitamin C versus placebo in 270 post cardiac arrest patient. Furthermore, she recently received the MSCA-DN grant of the EU for the BIO-MICRO (Biomarkers and Intervention Outcomes in Micronutrient Optimization) project. In this project 13 PhDs in 4 different countries (Netherlands, Germany, Ireland and Italy) will develop new analytics to enable reliably determination of functional micronutrient body status, investigate potential subphenotypes of patients most likely to benefit from micronutrient supplementation and enable guidance with appropriate timing of micronutrient therapy.

Dr. Jonathan Casey is a pulmonary and critical care physician and clinical researcher with a focus on conducting pragmatic comparative effectiveness clinical trials. He is the director of the Coordinating Center for the Pragmatic Critical Care Research Group, which has led more than 25 trials, enrolling more 50,000 patients. He has published more than 190 manuscripts, including 20 manuscripts in The New England Journal of Medicine or JAMA, and his research has identified multiple beneficial interventions that have changed care for critically ill patients around the world. 

Dr. Casey also serves as Co-PI of the NCATS-funded Vanderbilt Trial Innovation Center which supports the development and conduct of multi-center trials across the United States. He cares for patients in the Vanderbilt University Medical Intensive Care Unit.

Matthew W. Semler MD, MSc is an Associate Professor of Medicine, Anesthesiology, and Biomedical Informatics at Vanderbilt University where he practices as a critical care physician, serves as Associate Director of the Medical Intensive Care Unit, and directs the Center for Learning Healthcare. Dr. Semler co-directs the Pragmatic Critical Care Research Group, a network of emergency medicine, anesthesia, and critical care clinicians and researchers at 25 centers across the US that embeds pragmatic trials into clinical care to determine which treatments produce the best patient outcomes.

Randomized trials he has helped lead, including 15 published in the New England Journal of Medicine or JAMA, have identified effective treatments in the fields of fluid management, tracheal intubation, and respiratory support.