Critical Care Reviews Journal Watch

Saturday July 4th

Narrative Reviews

Clinical

• Lippi. COVID-19: unravelling the clinical progression of nature’s virtually perfect biological weapon. Ann Transl Med 2020;8(11):693
• Sahu. Trajectory of the COVID-19 pandemic: chasing a moving target. Ann Transl Med 2020;8(11):694
• Zhou. Potential therapeutic targets and promising drugs for combating SARS-CoV-2. Br J Pharmacol 2020;177(14):3147-3161
• Rodrigues‐Diez. Statins: Could an old friend help the fight against COVID‐19? Br J Pharmacol 2020;epublished June 19th
• Curtin. Repositioning PARP inhibitors for SARS‐CoV‐2 infection (COVID‐19); a new multi‐pronged therapy for ARDS? Br J Pharmacol 2020;epublished May 22nd
• Scavone. Current pharmacological treatments for COVID‐19: What's next? Br J Pharmacol 2020;epublished April 24th
• Ragab. The COVID-19 Cytokine Storm; What We Know So Far. Front Immunol 2020;11:1446
• Payen. The gut as a hidden source of sepsis. Minerva Anestesiologica 2020;86(6):662-9
  • Commentary: Cavaliere. The gut in the critically ill: hot topics and expert opinions. Minerva Anestesiologica 2020;86(6):583-5
• Sangalli. Levosimendan to facilitate weaning from cardiorespiratory support in critically ill patients: current evidence and future directions. Minerva Anestesiologica 2020;86(6):645-51
• Picozzi. Clinical ethics consultation in the intensive care unit. Minerva Anestesiologica 2020;86(6):670-7
• Seffer. Heparin 2.0: A New Approach to the Infection Crisis. Blood Purif 2020;epublished July 2nd
• Redant. Extracorporeal CO2 Removal Integrated within a Continuous Renal Replacement Circuit Offers Multiple Advantages. Blood Purif 2020;epublished June 25th
• AL Shareef. Cytokine Blood Filtration Responses in COVID-19. Blood Purif 2020;epublished May 28th
• Ponce. Acute peritoneal dialysis in the treatment of COVID-19-related acute kidney injury. Clinical Kidney Journal 2020;epublished June 30th
• Oliveira. SARS-CoV-2 and the COVID-19 disease: a mini review on diagnostic methods. Rev Inst Med trop S Paulo 2020;62:epublished June 29th
• Ellul. Neurological associations of COVID-19. Lancet Neurology 2020;epublished July 2nd
• Vijayvargiya. Treatment Considerations for COVID-19. A Critical Review of the Evidence (or Lack Thereof). Mayo Clin Proc 2020;95(7):1454-1466
• Razonable. A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease 2019 in the Hospital Setting. Mayo Clin Proc 2020;95(7):1467-1481
• Demaerschalk. Contemporary Management of Acute Ischemic Stroke Across the Continuum. From TeleStroke to Intra-Arterial Management. Mayo Clin Proc 2020;95(7):1512-1529

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Friday July 3rd

Guidelines & Position Statements

• Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM). Critical Care 2020 24:393
• Ronco. Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient during COVID-19 Pandemic: Expert Review and Recommendation.
  Blood Purif 2020;epublished May 26th
• Triage of Scarce Critical Care Resources in COVID-19 An Implementation Guide for Regional Allocation. An Expert Panel Report of the Task Force for Mass Critical Care and the American College of Chest Physicians. Chest 2020;158(1):212–225
• Prevention, Diagnosis, and Treatment of VTE in Patients With COVID-19. CHEST Guideline and Expert Panel Report. Chest 2020;epublished June 2nd
• Chao. Tracheotomy in Ventilated Patients With COVID-19. Ann Surg 2020;epublished May 5th

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Thursday July 2nd

Research

Randomised Controlled Trials

• Full Text:  Jehan. Randomized Trial of Amoxicillin for Pneumonia in Pakistan. N Engl J Med 2020;383:24-34
• Full Text:  Ginsburgh. Amoxicillin for 3 or 5 Days for Chest-Indrawing Pneumonia in Malawian Children. N Engl J Med 2020;383:13-23
• Full Text:  Iglesias. Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis. The ORANGES Trial. Chest 2020;158(1):164–173
• Full Text:  Chang. Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock. A Randomized Controlled Trial. Chest 2020;158(1):174–182
  
  • Editorial:  Fujii. Additional Trials of Vitamin C in Septic Shock. A Bag of Mixed Fruit. Chest 2020;158(1):13–14
• Full Text:  Wang. Mechanical Ventilation Strategy Guided by Transpulmonary Pressure in Severe Acute Respiratory Distress Syndrome Treated With Venovenous Extracorporeal Membrane Oxygenation. Crit Care Med 2020;epublished June 25th

Systematic Reviews & Meta Analyses

• Abstract:  Zayed. Use of glucocorticoids in patients with acute respiratory distress syndrome: a meta-analysis and trial sequential analysis. J Intensive Care 2020;8:43
• Abstract:  Osman. Induced Hypothermia in Patients with Cardiac Arrest and a Non-shockable Rhythm: Meta-analysis and Trial Sequential Analysis. Neurocrit Care 2020;epublished June 30th
• Full Text:  Brienza. Acute Kidney Injury in Coronavirus Disease 2019 Infected Patients: A Meta-Analytic Study. Blood Purif 2020;epublished July 2nd
• Full Text:  Chaudhuri. High flow nasal cannula in the immediate post-operative period: a systematic review and meta-analysis. Chest 2020;epublished June 29th
• Full Text:  Turner. Association of checklist use in endotracheal intubation with clinically important outcomes: a systematic review and meta-analysis. JAMA Netw Open 2020;3(7):e209278
  
  • Editorial:  Janz. Checklists for Tracheal Intubation of Critically Ill Adults. JAMA Netw Open 2020;3(7):e209511
• Full Text:  Zayed. Use of glucocorticoids in patients with acute respiratory distress syndrome: a meta-analysis and trial sequential analysis. J Intensive Care 2020;8:43
• Full Text:  Potere. Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis. Critical Care 2020;24:389
• Full Text:  Karam. Vasopressors and Inotropes in Acute Myocardial Infarction Related Cardiogenic Shock: A Systematic Review and Meta-Analysis. J Clin Med 2020;9(7):2051
• Abstract:  Parhar. Standardized Management for Hypoxemic Respiratory Failure and ARDS: Systematic Review & Meta-analysis. Chest 2020;epublished July 3rd
• Abstract:  Chaudhuri. High flow nasal cannula in the immediate post-operative period: a systematic review and meta-analysis. Chest 2020;epublished June 28th

Observational Studies

• Full Text:  Dufort. Multisystem Inflammatory Syndrome in Children in New York State. N Engl J Med 2020;epublished June 29th
• Full Text:  Feldstein. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med 2020;epublished June 29th
  
  • Editorial:  Levin. Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic. N Engl J Med 2020;epublished June 29th
• Abstract:  Bellomo. Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. Am J Respir Crit Care Med 2020;epublished June 30th
• Abstract:  Gershengorn. Association of Premorbid Blood Pressure with Vasopressor Infusion Duration in Patients with Shock. Am J Respir Crit Care Med 2020;202(1):91-99
  
  • Editorial:  Russell. Personalized Blood Pressure Targets in Shock: What If Your Normal Blood Pressure Is “Low”? Am J Respir Crit Care Med 2020;202(1):10-12
• Full Text:  Thorarinsdottir. Biofilm formation on three different endotracheal tubes: a prospective clinical trial. Critical Care 2020;24:382
• Abstract:  Soilemezi. Tissue Doppler Imaging of the Diaphragm in Healthy Subjects and Critically Ill Patients. Am J Respir Crit Care Med 2020;epublished July 2nd
• Abstract:  Loughlin. Pulmonary Aspergillosis in Patients with Suspected Ventilator-associated Pneumonia in UK Intensive Care Units. Am J Respir Crit Care Med 2020;epublished July 2nd
• Full Text:  Woolf. Excess Deaths From COVID-19 and Other Causes, March-April 2020. JAMA 2020;epublished July 1st
  
  • Editorial:  Zylke. Mortality and MorbidityThe Measure of a Pandemic. JAMA 2020;epublished July 1st
    • Podcast:  Weinberger. Estimation of Excess Deaths From COVID-19 in the United States, March to May 2020. JAMA 2020;epublished July 1st
• Abstract:  Panwar. Relative Hypotension and Adverse Kidney-related Outcomes Among Critically Ill Patients with Shock- A Multicenter Prospective Cohort Study. Am J Respir Crit Care Med. 2020;epublished July 2nd
• Full Text:  Goshua. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. Lancet Haematol 2020;epublished June 30th
  
  • Commentary:  O’Sullivan. Endothelial cells orchestrate COVID-19 coagulopathy. Lancet Haematol 2020;epublished June 30th
• Full Text:  Guaraldi. Tocilizumab in patients with severe COVID-19: a retrospective cohort study. Lancet Rheumatol 2020;epublished June 24th
  
  • Editorial:  Schulert. Can tocilizumab calm the cytokine storm of COVID-19? Lancet Rheumatol 2020;epublished June 24th
• Full Text:  Ketcham. Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study. Critical Care 2020;24:391
• Abstract:  Cnattingius. Apgar Score and Risk of Neonatal Death among Preterm Infants. N Engl J Med 2020;383:49-57
• Abstract:  Bergin. PROPHETIC: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit. Chest 2020;epublished June 29th
• Abstract:  Wijnberge. Defining Human Mean Circulatory Filling Pressure in the Intensive Care Unit. J Appl Physiol 2020;epublished July 2nd
• Abstract:   Bastos. Structure and Process Associated With the Efficiency of Intensive Care Units in Low-Resource Settings: An Analysis of the CHECKLIST-ICU Trial Database. J Crit Care 2020;59:118-123

Protocol

• Full Text:  Legrand. The I-MICRO Trial, Ilomedin for Treatment of Septic Shock With Persistent Microperfusion Defects: A Double-Blind, Randomized Controlled Trial-Study Protocol for a Randomized Controlled Trial. Trials 2020;21(1):601
• Full Text:  Faqihi. A pilot study of therapeutic plasma exchange for serious SARS CoV-2 disease (COVID-19): A structured summary of a randomized controlled trial study protocol. Trials 2020;21:506
• Full Text:  Eckhardt. Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial. Trials 2020;21:499
• Full Text:  Bosteels. Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:491
• Full Text:  Rilinger. A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:470
• Full Text:  Kawaguchi. Comparison of two methods to clear the airways of critically ill children and adults with COVID-19 infection: a structured summary of a study protocol for a pilot randomized controlled trial. Trials 2020;21:610
• Full Text:  Mills. Stress ulcer prophylaxis versus placebo—a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). Trials 2020;21:590
• Full Text:  Stockmann. CytoResc – “CytoSorb” Rescue for critically ill patients undergoing the COVID-19 Cytokine Storm: A structured summary of a study protocol for a randomized controlled trial. Trials 2020;21:577
• Full Text:  Pantos. Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:573
• Full Text:  Desilles. Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:548

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Wednesday July 1st

Narrative Reviews 

Clinical

• Desai. Endpoints used in phase III randomized controlled trials of treatment options for COVID-19. 2020;23(100403). EClinMed 2020;23(100403):
• Sinha. Is a “Cytokine Storm” Relevant to COVID-19? JAMA Intern Med 2016;epublished June 30th
• Keeley. Asymptomatic SARS-CoV-2 infection: the tip or the iceberg? Thorax 2020;epublished June 24th
• Whittaker. Using routine health data for research: the devil is in the detail. Thorax 2020;epublished June 24th
• McKenzie. A Cruel COVID-19 Irony. JAMA 2020;epublished June 30th
• Bentley. Guidance and Patient Instructions for Proning and Repositioning of Awake, Non‐Intubated COVID‐19 Patients. Acad Emerg Med 2020;epublished June 29th
• Wurmb. Hospital preparedness for mass critical care during SARS-CoV-2 pandemic. Critical Care 2020;24:386
• Hage. Calcineurin inhibitors revisited: A new paradigm for COVID-19? Braz J Infect Dis 2020;epublished June 27th
• El Ouali. Gastrointestinal manifestations of COVID-19. Clev Clin J Med 2020;epublished June 18th
• Miller. Clinical presentation and course of COVID-19. Clev Clin J Med 2020;87(7):384-388
• Calabrese. Cytokine storm and the prospects for immunotherapy with COVID-19. Clev Clin J Med 2020;87(7):389-393
• Kadkhoda. COVID-19 serologic testing: FAQs and caveats. Clev Clin J Med 2020;87(7):329-333
• Bergmann. COVID-19: Coronavirus replication, pathogenesis, and therapeutic strategies. Clev Clin J Med 2020;87(7):321-327
• Tsigrelis. Recurrent Clostridioides difficile infection: Recognition, management, prevention. Clev Clin J Med 2020;87(7):347-359
• Cost. Medical complications of anorexia nervosa. Clev Clin J Med 2020;87(7):361-366
• Hatipoğlu. Can multiple ARDS patients be ventilated with a single ventilator?. Clev Clin J Med 2020;87(7):259-261
• Laktineh. What mask should I wear to protect against transmissible acute respiratory infections? Clev Clin J Med 2020;87(7):262-265
• Prasad. Should I prone non-ventilated awake patients with COVID-19? Clev Clin J Med 2020;87(7):
• Cheng. COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach. Clev Clin J Med 2020;87(7):
• Bradley. Burnout of healthcare providers during COVID-19. Clev Clin J Med 2020;87(7):
• Rice. In Defense of Evidence-based Medicine for the Treatment of COVID-19 Acute Respiratory Distress Syndrome. Ann Am Thorac Soc 2020;17(7):787-789
• Deming. COVID-19 and Lessons to Be Learned from Prior Coronavirus Outbreaks. Ann Am Thorac Soc 2020;17(7):790-794
• Seethala. Extracorporeal Membrane Oxygenation Resource Planning in the Setting of Pandemic Respiratory Illness. Ann Am Thorac Soc 2020;17(7):800-803
• Guglielmetti. “War to the knife” against thromboinflammation to protect endothelial function of COVID-19 patients. Critical Care 2020 24:365

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Tuesday June 30th

Narrative Reviews

Clinical

• Jerath. Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS. Intensive Care Med 2020;epublished June 25th
• Schiavone. Acute Coronary Syndromes and Covid-19: Exploring the Uncertainties. J Clin Med 2020;9(6):1683
• Allam. COVID-19 Diagnostics, Tools, and Prevention. Diagnostics 2020;10(6):409
• Zaragoza. Update of the treatment of nosocomial pneumonia in the ICU. Critical Care 2020;24:383
• Udwadia. The N-95 mask: invaluable ally in the battle against the COVID-19 pandemic. Lung India 2020;37:323-8
• Pearce. The cytokine storm of COVID-19: a spotlight on prevention and protection. Expert Opinion on Therapeutic Targets 2020;epublished June 27th
• Yang. Corticosteroid administration forviral pneumonia: COVID-19 and beyond. Clin Microbiol and Infec 2020;epublished June 27th
• Mangalmurti. Cytokine Storms: Understanding COVID-19. Immunity 2020;epublished June 28th
• Nicholson. Respiratory failure and non-invasive respiratory support during the covid-19 pandemic: an update for re-deployed hospital doctors and primary care physicians. BMJ 2020;369:m2446
• Kalra. Cause for Confusion: Noncirrhotic Hyperammonemic Encephalopathy. Clin Liver Dis 2020;15(6):223-227

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Monday June 29th

Research

Randomized Controlled Trials

• Press Release: No clinical benefit from use of lopinavir-ritonavir in hospitalised COVID-19 patients studied in RECOVERY. Statement from the Chief Investigators of the Randomised Evaluation of COVid-19 thERapY (RECOVERY) Trial on lopinavir-ritonavir, 29 June 2020

Commentaries

• Valley. ICU beds: less is more? Yes. Intensive Care Med 2020;epublished April 25th
• de Lange. ICU beds: less is more? No. Intensive Care Med 2020;epublished May 26th
• Phua. ICU beds: less is more? Not sure. Intensive Care Med 2020;epublished June 22nd

• Sunday June 28th

  Research

  Randomised Controlled Trials

  • Abstract:  Wang. Mechanical Ventilation Strategy Guided by Transpulmonary Pressure in Severe Acute Respiratory Distress Syndrome Treated With Venovenous Extracorporeal Membrane Oxygenation. Crit Care Med 2020;epublished June 25th

  Systematic Reviews & Meta Analyses

  • Full Text:  Chu. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet 2020;395(10242):1973-1987
    • Commentary: MacIntyre. Physical distancing, face masks, and eye protection for prevention of COVID-19. Lancet 2020;395(10242):1950-1951
  • Full Text:  Hoang. COVID-19 in 7780 pediatric patients: A systematic review. Lancet 2020;epublished June 26th

  Observational Studies

  • Abstract:  Daigle. Difficult Bag-Mask Ventilation in Critically Ill Children Is Independently Associated With Adverse Events. Crit Care Med 2020;epublished June 25th

  Guidelines & Position Statements

  • Updated Guidelines to Reduce Venous Thromboembolism in Trauma Patients: A Western Trauma Association Critical Decisions Algorithm. J Trauma Acute Care Surg 2020;epublished June 24th
  • Pediatric Airway Management in COVID-19 Patients: Consensus Guidelines From the Society for Pediatric Anesthesia’s Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society. Anesth Analg 2020;131(1):61-73

  Narrative Reviews

  Clinical

  • Stahlmann. Medication for COVID-19—an Overview of Approaches Currently Under Study. Dtsch Arztebl Int 2020;117:213-9
  • Manjili. COVID-19 as an Acute Inflammatory Disease. J Immunol. 2020 Jul 1;205(1):12-19
  • Dexter. Perioperative COVID-19 Defense: An Evidence-Based Approach for Optimization of Infection Control and Operating Room Management. Anesth Analg 2020;131(1):37-42
  • Sommer. Initial Clinical Impressions of the Critical Care of COVID-19 Patients in Seattle, New York City, and Chicago. Anesth Analg 2020;131(1):55-60
  • Shander. Essential Role of Patient Blood Management in a Pandemic: A Call for Action. Anesth Analg 2020;131(1):74-85
  • Bong. The COVID-19 Pandemic: Effects on Low- and Middle-Income Countries. Anesth Analg 2020;131(1):86-92                                                            
  • Ludwig. Coronaviruses and SARS-CoV-2: A Brief Overview. Anesth Analg 2020;131(1):93-96
  • Chen. To Protect Health Care Workers Better, To Save More Lives With COVID-19. Anesth Analg 2020;131(1):97-101
  • Albott. Battle Buddies: Rapid Deployment of a Psychological Resilience Intervention for Health Care Workers During the COVID-19 Pandemic. Anesth Analg 2020;131(1):43-54
  • Kelava. Regional Anesthesia in Cardiac Surgery: An Overview of Fascial Plane Chest Wall Blocks. Anesth Analg 2020;131(1):127-135
    • Infographic. Nathan. Playing it Close to the Chest: Regional Anesthesia Techniques for Cardiac Surgery. Anesth Analg 2020;131(1):124
  • Eisenman. Rereading Arrowsmith in the COVID-19 Pandemic. JAMA 2020;epublished June 26th
  • Austin. The State of Health Care Quality Measurement in the Era of COVID-19The Importance of Doing Better. JAMA 2020;epublished June 25th
    

  Videos

  • Machado. Coronavirus in Brazil - Report From The Front Lines. JAMA 2020;epublished June 26th
  • Osterholm. Coronavirus Q&A: The Next COVID-19 Phase. JAMA 2020;epublished June 24th

  Podcasts

  • Rubin. Audio Interview: The Challenges of Safe Reopening. N Engl J Med 2020;382:e113

  News

  • Heidt. Arctic Swelters Under 38 °C Heat Wave. The possibly record-breaking temps follow the warmest winter on record in the region. Scientist 2020;epublished June 24th

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  Saturday June 27th

  Editorials

  • Mukhtyar. Hydroxychloroquine and coronavirus disease 2019. J R Coll Physicians Edinb 2020;50:102–4
  • Gusman. Hypoxemia on life support for guiding acute respiratory distress syndrome therapy? J Thorac Dis 2020;12(6):3010-3012
  • Ramnath. Addressing the “What do we have to lose? Just give the drug” rationale: making the case for clinical trials and against off-label use in COVID-19. J Thorac Dis 2020;12(6):3031-3034
  • Park. Can parapneumonic effusion be diagnosed only with pleural fluid analysis? J Thorac Dis 2020;12(6):3422-3425
  • Bauchner. Editorial Evaluation and Peer Review During a PandemicHow Journals Maintain Standards. JAMA 2020;epublished June 26th
  • Smyth. Preprint servers: a ‘rush to publish’ or ‘just in time delivery’ for science? Thorax 2020;75:532-533

  Correspondence

  • Muller. COVID-19, nuclear war, and global warming: lessons for our vulnerable world. Lancet 2020;395(10242):1967-1968
  • Gabster. Challenges for the female academic during the COVID-19 pandemic. Lancet 2020;395(10242):1968-1970
  • Sipido. Overcoming fragmentation of health research in Europe: lessons from COVID-19. Lancet 2020;395(10242):1970-1971
  • Devakumar. Racism, the public health crisis we can no longer ignore. Lancet 2020;395(10242):e112-e113
  • Hanidziar. Sedation of Mechanically Ventilated COVID-19 Patients: Challenges and Special Considerations. Anesth Analg 2020;131(1):e40-e41

  Case Reports

  • Gaeta. Case 21-2020: A 66-Year-Old Homeless Man with Covid-19. N Engl J Med 2020;epublished June 24th
  • Gnecchi. Myocarditis in a 16-year-old boy positive for SARS-CoV-2. Lancet 2020;395(10242):e116
  • Geerdes-Fenge. Pulmonary Artery Embolism in COVID-19 Despite Thrombosis Prophylaxis. Dtsch Arztebl Int 2020;117:297
  • Schuster. A Moderate Case of COVID-19 Viral Pneumonia During the SARS-CoV-2 Pandemic. Dtsch Arztebl Int 2020;117:219
  • León. Acute coronary syndrome and shock in the context of acute COVID-19 infection. Rev Esp Cardiol 2020;epublished June 13th

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  Friday June 26th

  Commentaries

  • Gollob. COVID-19, Clinical Trials, and QT-Prolonging Prophylactic Therapy in Healthy Subjects. First, Do No Harm. JACC 2020;75(25):3184-3186
  • Thalha. Have we found the panacea to COVID-19 with remdesivir, an old but newly packaged drug? J R Coll Physicians Edinb 2020;50:159–61
  • Prasad. On the Frontlines of the Coronavirus Disease 2019 (COVID-19) Crisis—The Many Faces of Leadership. JAMA Cardiol 2020;epublished June 24th
  • Austin. The State of Health Care Quality Measurement in the Era of COVID-19. The Importance of Doing Better. JAMA 2020;epublished June 25th
  • White. A Proposed Lottery System to Allocate Scarce COVID-19 Medications. Promoting Fairness and Generating Knowledge. JAMA 2020;epublished June 24th
  • Sarpatwari. Missed Opportunities on Emergency Remdesivir Use. JAMA 2020;epublished June 24th
  • Fessell. Laughter Leaves Me Lighter. Coping With COVID-19. JAMA 2020;323(24):2476-2477
  • Nolen. How Medical Education Is Missing the Bull’s-eye. N Engl J Med 2020; 382:2489-2491
  • Treweek. COVID-19 and ethnicity: who will research results apply to? Lancet 2020;395(10242):1955-1957
  • Horton. Offline: The second wave. Lancet 2020;395(10242):1960
  • Camporota. Identification of pathophysiological patterns for triage and respiratory support in COVID-19. Lancet 2020;epublished June 26th
  • Tavare. Managing high clinical suspicion COVID-19 inpatients with negative RT-PCR: a pragmatic and limited role for thoracic CT. Thorax 2020;75:537-538
  • Abd-Elsayed. Utility of Substandard Face Mask Options for Health Care Workers During the COVID-19 Pandemic. Anesth Analg 2020;131(1):4-6
  • Chow. Angiotensin II for the Treatment of COVID-19–Related Vasodilatory Shock. Anesth Analg 2020;131(1):102-105
  • Sasangohar. Provider Burnout and Fatigue During the COVID-19 Pandemic: Lessons Learned From a High-Volume Intensive Care Unit. Anesth Analg 2020;131(1):106-111
  • Vittori. COVID-19 Pandemic Acute Respiratory Distress Syndrome Survivors: Pain After the Storm? Anesth Analg 2020;131(1):117-119
  • Marco. Anesthesiology, the Tragedy of the Commons, and COVID-19. Anesth Analg 2020;131(1):120-123
  • McLester. Clearness in Medical Speech. JAMA 2020;323(24):2532   (Originally Published JAMA 1920;74(19):1295-1296)

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  Thursday June 25th

  Narrative Reviews

  Clinical

  • Liaw. Emerging therapies in acute ischemic stroke. F1000Research 2020;9(F1000 Faculty Rev):546
  • Seger. Recent advances in the technology of anesthesia. F1000Research 2020;9(F1000 Faculty Rev):375
  • Hasegawa. Recent advances in managing and understanding Stevens-Johnson syndrome and toxic epidermal necrolysis. F1000Research 2020;9(F1000 Faculty Rev):612
  • Kerbert. Recent advances in understanding and managing hepatic encephalopathy in chronic liver disease. F1000Research 2020;9(F1000 Faculty Rev):312
  • Zavvarian. Novel innovations in cell and gene therapies for spinal cord injury. F1000Research 2020;9(F1000 Faculty Rev):279
  • Späth. Preconditioning strategies to prevent acute kidney injury. F1000Research 2020;9(F1000 Faculty Rev):237
  • Madahar. Emerging concepts in ventilation-induced lung injury. F1000Research 2020;9(F1000 Faculty Rev):222
  • Feldman. Recent advances in the epidemiology and prevention of Streptococcus pneumoniae infections. F1000Research 2020;9(F1000 Faculty Rev):338
  • Chakraborty. The COVID-19 pandemic: catching up with the cataclysm. F1000Research 2020;9(F1000 Faculty Rev):638

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  Wednesday June 24th

  Research

  Randomised Controlled Trials

  • Abstract:  Landrigan. Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts. N Engl J Med 2020; 382:2514-2523
  • Abstract:  Lomivorotov. Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac SurgeryThe DECISION Randomized Clinical Trial. JAMA 2020;323(24):2485-2492
  • Abstract:  Kim. Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome. The TICO Randomized Clinical Trial. JAMA 2020;323(23):2407-2416
  • Full Text: Deftereos. Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019. The GRECCO-19 Randomized Clinical Trial. JAMA Netw Open 2020;3(6):e2013136
    
    • Editorial:  Rabbani. Colchicine for the Treatment of Myocardial Injury in Patients With Coronavirus Disease 2019 (COVID-19)—An Old Drug With New Life? JAMA Netw Open 2020;3(6):e2013556

  Observational Study

  • Abstract:  Australian Genomics Health Alliance Acute Care Flagship. Feasibility of Ultra-Rapid Exome Sequencing in Critically Ill Infants and Children With Suspected Monogenic Conditions in the Australian Public Health Care System. JAMA 2020;323(24):2503-2511

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  Tuesday June 23rd

  Narrative Reviews

  Clinical

  • Kadri. Key Takeaways From the U.S. CDC’s 2019 Antibiotic Resistance Threats Report for Frontline Providers. Crit Care Med 2020;48(7):939-945
  • Bonam. Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients. Cell Rep Med 2020;1(2):100016
  • Wong. Consequences and Solutions for the Impact of Communication Impairment on Noninvasive Ventilation Therapy for Acute Respiratory Failure: A Focused Review. Crit Care Explor 2020;2(6):e0121
  • Susen. Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring. Critical Care 2020;24:364
  • Iba. The unique characteristics of COVID-19 coagulopathy. Critical Care 2020;24:360
  • Lipworth. Emerging pharmacotherapy for COVID-19. J R Coll Physicians Edinb 2020;50:133–7

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  Monday June 22nd

  Research

  Randomised Controlled Trials

  • Preprint:  Horby. Effect of Dexamethasone in Hospitalized Patients with COVID-19 – Preliminary Report. medRxiv 2020;epublished June 22nd

  Systematic Reviews & Meta Analyses

  • Abstract:  Kim. Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials. Crit Care Med 2020;48(7):1047-1054
  • Abstract:  Waldauf. Effects of Rehabilitation Interventions on Clinical Outcomes in Critically Ill Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Crit Care Med 2020;48(7):1055-1065
  • Abstract:  Honarmand. A Systematic Review of Risk Factors for Sleep Disruption in Critically Ill Adults. Crit Care Med 2020;48(7):1066-1074

  Observational Studies

  • Full Text:  Sauro. Adverse Events After Transition From ICU to Hospital Ward: A Multicenter Cohort Study. Crit Care Med 2020;48(7):946-953
    
    • Editorial:  Co. Lost in Transition: A Call to Arms for Better Transition From ICU to Hospital Ward. Crit Care Med 2020;48(7):1075-1076
  • Abstract:  Rush. Treatment in Disproportionately Minority Hospitals Is Associated With Increased Risk of Mortality in Sepsis: A National Analysis. Crit Care Med 2020;48(7):962-967
    
    • Editorial:  Barbash. Disparities in Sepsis Outcomes: A Problem in Need of Solutions. Crit Care Med 2020;48(7):1079-1080
  • Abstract:  Diehl. Association Between Arterial Carbon Dioxide Tension and Clinical Outcomes in Venoarterial Extracorporeal Membrane Oxygenation. Crit Care Med 2020;48(7):977-984
  • Abstract:  Rayes. Concomitant Aspirin and Anticoagulation Is Associated With Increased Risk for Major Bleeding in Surgical Patients Requiring Postoperative Intensive Care. Crit Care Med 2020;48(7):985-992

Sunday June 21st

Research

Systematic Reviews & Meta Analyses

• Full Text:  Qu. Cell‐based therapy to reduce mortality from COVID‐19: Systematic review and meta‐analysis of human studies on acute respiratory distress syndrome. Stem Cells Transl Med 2020;epublished May 29th
• Full Text:  Shelmerdine. Coronavirus disease 2019 (COVID-19) in children: a systematic review of imaging findings. Pediatr Radiol 2020;epublished June 18th
• Full Text:  Mallama. A systematic review and trial sequential analysis of intravenous vs. oral peri‐operative paracetamol. Anaesthesia 2020;epublished June 18th
• Full Text:  Fawaz. Comparing clinical outcomes of piperacillin-tazobactam administration and dosage strategies in critically ill adult patients: a systematic review and meta-analysis. BMC Infectious Diseases 2020;20:430
• Full Text:  Yang. Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysis. Crit Care 2020;24(1):356

Observational Studies

• Full Text:  Thompson. Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure. JAMA Intern Med 2020;epublished June 17th
  
  • Editorial:  Sarma. Prone Positioning in Awake, Nonintubated Patients With COVID-19Necessity Is the Mother of Invention. JAMA Intern Med 2020;epublished June 17th
• Full Text:  Fosbøl. Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality. JAMA 2020;epublished June 19th
  
  • Editorial:  Curfman. Renin-Angiotensin-Aldosterone Inhibitors and Susceptibility to and Severity of COVID-19. JAMA 2020;epublished June 19th
• Full Text:  Ellinghaus. Genomewide Association Study of Severe Covid-19 with Respiratory Failure. N Engl J Med 2020;epublished June 17th
• Abstract:  Yu. Hypermetabolism and COVID-19. JPEN J Parenter Enteral Nutr 2020;epublished June 19th
• Full Text:  Kaushik. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection: A Multi-institutional Study from New York City. J Pediatr 2020;epublished June 14th

Guidelines & Position Statements

• ACE Consensus Group. The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 2020;21:528

Narrative Reviews

Clinical

• Madhivathanan. Perioperative implications of pericardial effusions and cardiac tamponade. BJA Education 2020;20(7):226-234
• Shelton. Anaesthesia for hip fracture repair. BJA Education 2020;20(5):142-149
• Delgado. General anaesthesia in obstetrics. BJA Education 2020;20(6):201-207
• Colling. COVID-19-associated coagulopathy: An exploration of mechanisms. Vasc Med 2020;epublished June 19th
• Dogrul. Blunt trauma related chest wall and pulmonary injuries: An overview. Chin J Traumatol 2020;23(3):125–138
• Heath. Resilience strategies to manage psychological distress amongst healthcare workers during the COVID‐19 pandemic: a narrative review. Anaesthesia 2020;epublished June 13th
• Prasad. COVID-19 and the cardiovascular system: A review of current data, summary of best practices, outline of controversies and illustrative case reports. Am Heart J 2020;epublished June 15th
• Lin. The severe COVID-19: a sepsis induced by viral infection? And its immunomodulatory therapy. Chinese Journal of Traumatology 2020;epublished June 15th
• Toni. A revolution in stroke therapy: reperfusion therapy effective even if late. Eur Heart J 2020;22(Suppl E):E157–E161
• Almeida. Adrenal Insufficiency and Glucocorticoid Use During the COVID-19. Clinics (Sao Paulo) 2020;75:e2022
• Varghese. Clinical management of COVID-19. Indian J Med Res 2020;151:401-10
• den Hollander. Palliation, end-of-life care and burns; concepts, decision-making and communication – A narrative review. Af J Emerg Med 2020;10(2):95-98

Non-Clinical

• Webb. Bayes’ formula: a powerful but counterintuitive tool for medical decision-making. BJA Educationn 2020;20(6):208e213

Seminars in Nephrology series on Social Media in Nephrology

• Topf. Introduction: Social Media and Medical Education Come of Age. Semin Nephrol 2020;40(3):247-248
• O'Glasser. To Tweet or Not to Tweet, That Is the Question. Semin Nephrol 2020;40(3):249-263
• Stoneman. Twitter-Based Journal Clubs: Bringing Critical Appraisal to the Social Table. Semin Nephrol 2020;40(3):264-272
• Breu. From Tweetstorm to Tweetorials: Threaded Tweets as a Tool for Medical Education and Knowledge Dissemination. Semin Nephrol 2020;40(3):273-278
• Rodman. Podcasting: A Roadmap to the Future of Medical Education. Semin Nephrol 2020;40(3):279-283
• Colbert. Newsletters in Medical Education. Semin Nephrol 2020;40(3):284-290
• Ramos. Visual Abstracts: Redesigning the Landscape of Research Dissemination. Semin Nephrol 2020;40(3):291−297
• Lin. Picking Up the Slack: Collaboration Tools to Build Community and Increase Productivity in Nephrology. Semin Nephrol 2020;40(3):298-302
• Pandya. Use of Semiprivate Smartphone Communication Applications in Nephrology Education. Semin Nephrol 2020;40(3):303-308
• Ting. Quality Appraisal and Assurance Techniques for Free Open Access Medical Education (FOAM) Resources: A Rapid Review. Semin Nephrol 2020;40(3):309-319
• Ramakrishnan. Training the Public Physician: The Nephrology Social Media Collective Internship. Semin Nephrol 2020;40(3):320-327

Editorials

• Fawcett. Education and scientific dissemination during the COVID‐19 pandemic. Anaestesia 2020;epublished June 18th
• Huertas. Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)? Eur Respir J 2020;epublished June 18th

Commentaries

• Langlume. Metaphor use in the ICU: rigor with words! Intensive Care Med 2020;epublished June 18th
• Bamba. Can Mesenchymal Stem Cell Therapy Be the Interim Management of COVID-19? Drug Discov Ther 2020;epublished June 16th
• Ng. Prejudice in science - Lessons from the coronavirus story. Phys Med 2020;75:83-84

Correspondence

• Ahlström. Immortal time bias: a possible explanation for “Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication”. Crit Care 2020;24:355
• Honore. Liver injury without liver failure in COVID-19 patients: how to explain, in some cases, elevated ammonia without hepatic decompensation. Crit Care 2020;24:352
• Tsolaki. The ARDSnet protocol may be detrimental in COVID-19. Crit Care 2020;24:351
• Carr. Micronutrient status of COVID-19 patients: a critical consideration. Crit Care 2020;24:349
• Drewry. Response to “COVID-19: room for treating T cell exhaustion?”. Crit Care 2020;24:345
• Lal. Optic nerve sheath diameter in critically ill patients: nuances and interpretation. Crit Care 2020;24:343
• Cao. Clinical features and outcomes of COVID-19 patients with gastrointestinal symptoms. Crit Care 2020;24:340
• Li. COVID-19 targets the right lung. Crit Care 2020;24:339
• Japan ECMOnet for COVID-19. Save the ICU and save lives during the COVID-19 pandemic. J Intensive Care 2020;8:40
• Stahl. First do no harm—beware the risk of therapeutic plasma exchange in severe COVID-19. Crit Care 2020;24:363

Case Reports

• Hasan. Takotsubo cardiomyopathy and its variants: a case series and literature review, Journal of Community Hospital Internal Medicine Perspectives 2020;10(3):210-215

Video

• Coronavirus Q&A: Clinical Update with Carlos del Rio, MD. JAMA 2020;epublished June 15th

Podcast

• Rubin. Audio Interview: A Look at SARS-CoV-2 Transmission. N Engl J Med 2020;382(25):e112

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Saturday June 20th

Research

Observational Studies

• Full Text:  Coppo. Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study. Lancet Respir Med 2020;epublished June 19th
  • Commentary:  Munshi. Prone positioning in non-intubated patients with COVID-19: raising the bar. Lancet Respir Med 2020;epublished June 19th
   

News

• The ORCHID Study (Outcomes Related to COVID-19 treated with hydroxychloroquine among In-patients with symptomatic Disease), from PETAL (Prevention and Early Treatment of Acute Lung Injury) Clinical Trials Network of NHLBI has stopped. NIH Press Release June 20th, 2020.

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Friday June 19th

Research

Randomised Controlled Trials

• Full Text:  The HALT-IT Trial Collaborators. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020;395(10241):1927-1936

Systematic Reviews & Meta Analyses

• Full Text:  Chen. Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis. Crit Care 2020;24:346

Observational Studies

• Full Text:  Hua. Invasive mechanical ventilation in COVID-19 patient management: the experience with 469 patients in Wuhan. Crit Care 2020;24:348
• Full Text:  Hordijk. Health-related quality of life of children and their parents 2 years after critical illness: pre-planned follow-up of the PEPaNIC international, randomized, controlled trial. Crit Care 2020;24:347
• Full Text:  Verity. Estimates of the severity of coronavirus disease 2019: a model-based analysis. Lancet Infect Dis 2020;20(6):669-677
  
  • Editorial:  Ruan. Likelihood of survival of coronavirus disease 2019. Lancet Infect Dis 2020;20(6):630-631
• Full Text:  Kucharski. Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study. Lancet Infect Dis 2020;epublished June 16th
  
  • Commentary:  MacIntyre. Case isolation, contact tracing, and physical distancing are pillars of COVID-19 pandemic control, not optional choices. Lancet Infect Dis 2020;epublished June 16th
• Full Text:  Carsana. Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive. Lancet Infect Dis 2020;epublished June 8th
  
  • Commentary:  Yi. Pathologists in pursuit of the COVID-19 culprit. Lancet Infect Dis 2020;epublished June 8th
• Full Text:  Cardot-Leccia. Pericyte alteration sheds light on micro-vasculopathy in COVID-19 infection. Intensive Care Med 2020;epublished June 12th

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Thursday June 18th

Narrative Reviews

Clinical

• Renew. Neuromuscular blockade management in the critically Ill patient. J Intensive Care 2020;8:37
• Lerner. Hyponatremia in the Neurologically Ill Patient: A Review. The Neurohospitalist 2020;10(3):208-21
• Kwenandar. Coronavirus Disease 2019 and Cardiovascular System: A Narrative Review. Int J Cardiol Heart Vasc 2020;29:100557
• Verdecchia. The Pivotal Link Between ACE2 Deficiency and SARS-CoV-2 Infection. Eur J Intern Med 2020;76:14-20

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Wednesday June 17th

Narrative Reviews

Clinical

• Pons. The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection. Critical Care 2020;24:353
• Mehta. Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities. Lancet Respr Med 2020;epublished June 16th
• Pohanka. D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection. BioMed Research International 2020;Article ID 3419034
• Becker. Toward understanding the 2019 Coronavirus and its impact on the heart. J Thromb Thrombolysis 2020;50:33–42
• Becker. COVID-19 update: Covid-19-associated coagulopathy. J Thromb Thrombolysis 2020;50:54–67
• Porfidia. Venous thromboembolism and heparin use in COVID-19 patients: juggling between pragmatic choices, suggestions of medical societies and the lack of guidelines. J Thromb Thrombolysis 2020;50:68–71
• Barnes. Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum. J Thromb Thrombolysis 2020;50:72–81
• Gabarre. Acute kidney injury in critically ill patients with COVID-19. Intensive Care Med 2020;epublished June 12th

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Tuesday June 16th

News

• RECOVERY Trial Investigators. Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19. Press Release June 16th

Commentaries

• WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection. A minimal common outcome measure set for COVID-19 clinical research. Lancet Infect Dis 2020;epublished June 12th
• Salluh. Delivering evidence-based critical care for mechanically ventilated patients with COVID-19. Lancet Respir Med 2020;epublished June 16th
• Marovich. Monoclonal Antibodies for Prevention and Treatment of COVID-19. JAMA 2020;epublished June 15th
• Fuchs. Health Care Policy After the COVID-19 Pandemic. JAMA 2020;epublished June 12th
• Berwick. The Moral Determinants of Health. JAMA 2020;epublished June 12th
• Galea. COVID-19 Pandemic, Unemployment, and Civil UnrestUnderlying Deep Racial and Socioeconomic Divides. JAMA 2020;epublished June 12th
• Editorial:  Bauchner. 2020—A Year That Will Be Remembered. JAMA 2020;epublished June 12th
• Bond. Socially Distanced Medicine. JAMA 2020;323(23):2383
• Gostin. COVID-19 Reveals Urgent Need to Strengthen the World Health Organization. JAMA 2020;323(23):2361-2362
• Rubin. Building an “Army of Disease Detectives” to Trace COVID-19 Contacts. JAMA 2020;323(23):2357-2360
• Editorial:  Steinbrook. Contact Tracing, Testing, and Control of COVID-19—Learning From Taiwan. JAMA Intern Med 2020;epublished May 1st
• Frasier. Coronavirus Antibody Tests Have a Mathematical Pitfall. Scientific American 2020;323(1):12-13
• Fischetti. A Visual Guide to the SARS-CoV-2 Coronavirus. Scientific American 2020;323(1):32-37

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Monday June 15th

Narrative Reviews

Clinical

• Sniderman. Hematologic concerns in extracorporeal membrane oxygenation. Res Pract Thromb Haemost 2020;4(4):455–468
• Shatzel. The contact activation system as a potential therapeutic target in patients with COVID‐19. RRes Pract Thromb Haemost 2020;4(4):500– 505
• Griffin. COVID‐19 hypothesis: Activated protein C for therapy of virus‐induced pathologic thromboinflammation. Res Pract Thromb Haemost 2020;4(4):506-509
• Cohoon. Emergence of institutional antithrombotic protocols for coronavirus 2019. Res Pract Thromb Haemost 2020;4(4):510– 517
• Liu. Using heparin molecules to manage COVID‐2019. Res Pract Thromb Haemost 2020;4(4):518– 523
• Barrett. Fibrinolytic therapy for refractory COVID‐19 acute respiratory distress syndrome: Scientific rationale and review. Res Pract Thromb Haemost 2020;4(4):524– 531

Sunday June 14th

Commentaries

• Gill. The Importance of Proper Death Certification During the COVID-19 Pandemic. JAMA 2020;epublished June 10th
• Villarreal-Fernandez. A plea for avoiding systematic intubation in severely hypoxemic patients with COVID-19-associated respiratory failure. Crit Care 2020;24:337
• Convertino. Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients. Crit Care 2020;24:331
• Fuchs. Health Care Policy After the COVID-19 Pandemic. JAMA 2020;epublished June 12th
• Galea. COVID-19 Pandemic, Unemployment, and Civil UnrestUnderlying Deep Racial and Socioeconomic Divides. JAMA 2020;epublished June 12th
• Berwick. The Moral Determinants of Health. JAMA 2020;epublished June 12th
• Jalkanen. Interferon beta-1a for COVID-19: critical importance of the administration route. Crit Care 2020;24:335
• Gossen. The Isolation Communication Management System. A Telemedicine Platform to Care for Patients in a Biocontainment Unit. Annals ATS 2020;17(6):673–678

Correspondence

• Alfano. The Role of the Renin-Angiotensin System in Severe Acute Respiratory Syndrome-CoV-2 Infection. Blood Purif 2020;epublished April 28th
• Hoshino. Early versus late tracheostomy in patients with traumatic brain injury. Intensive Care Med 2020;46:1286–1287
• Kreitmann. Cyclosporine A prevents cardiac arrest-induced acute respiratory failure: a post-hoc analysis of the CYRUS trial. Intensive Care Med 2020;46:1281–1283
• Sakurai. Natural History of Asymptomatic SARS-CoV-2 Infection. N Engl J Med 2020;epulished June 12th
• Soloman. Neuropathological Features of Covid-19. N Engl J Med 2020;epulished June 12th
• Ferrandis. COVID-19: opening a new paradigm in thromboprophylaxis for critically ill patients? Crit Care 2020;24:332
• Mahjoub. Severe Covid-19 disease: rather AVDS than ARDS? Crit Care 2020;24:327

Case Reports

• Harkin. Delayed diagnosis of COVID-19 in a 34-year-old man with atypical presentation. Lancet Respir Med 2020;8(6):644-646
• Kazi. Case 18-2020: A 73-Year-Old Man with Hypoxemic Respiratory Failure and Cardiac Dysfunction. N Engl J Med 2020;382:2354-2364

Videos

• Bauchner. Coronavirus Q&A: Critical Care Update. JAMA 2020;epublished June 8th
• Coronavirus Disease 2019 (COVID-19) and Surgical Complications. JAMA 2020;epublished June 12th

Podcasts

• Rubin. Audio Interview: The Impact of Covid-19 on Minority Communities. N Engl J Med 2020;382:e111

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Saturday June 13th

Editorials

• Tan. Intra-hospital preventive principles to protect frontline healthcare workers to overcome pandemic COVID-19 in Taiwan. Crit Care 2020;24:328
• Ronco. Coronavirus Epidemic and Extracorporeal Therapies in Intensive Care: si vis pacem para bellum. Blood Purif 2020;49:255–258
• Taylor. Sometimes more is not always better: ScvO2 monitoring in pediatric sepsis. Intensive Care Med 2020;46:1264–1266
• Evans. Diagnosing and Treating Systemic Racism. N Engl J Med 2020;epublished June 10th
• Ye. Infection prevention and control in nursing severe coronavirus disease (COVID-19) patients during the pandemic. Crit Care 2020;24:338

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Friday June 12th

Narrative Reviews

Clinical

• Chen. Cardiac injuries in coronavirus disease 2019 (COVID-19). J Mol Cell Cardiol 2020;145:25-29
• Imazio. COVID-19 pandemic and troponin: indirect myocardial injury, myocardial inflammation or myocarditis? Heart 2020;epublished June 4th
• Levi. Coronavirus Disease 2019 Coagulopathy: Disseminated Intravascular Coagulation and Thrombotic Microangiopathy—Either, Neither, or Both. Semin Thromb Hemost 2020;epublished June 8th
• Leibner. Damage control resuscitation. Clin Exp Emerg Med 2020;7(1):5-13

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Thursday June 11th

Research

Randomised Controlled Trials

• Abstract:  Zampieri. Bundle of Coated Devices to Reduce Nosocomial Infections in the Intensive Care Unit: CRITIC Pilot Randomized Controlled Trial. Annals ATS 2020;epublished June 11thAnnals ATS 2020;epublished June 11th
• Abstract:  Martins. Thrombectomy for Stroke in the Public Health Care System of Brazil. N Engl J Med 2020;382:2316-2326

Observational Studies

• Abstract:  Robert. Sedation practice and discomfort during withdrawal of mechanical ventilation in critically ill patients at end-of-life: a post-hoc analysis of a multicenter study. Intensive Care Med 2020;46:1194–1203
• Full Text:  McGuigan. The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study. Crit Care 2020;24:336

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Wednesday June 10th

Commentaries

• Gostin. The Dual Epidemics of COVID-19 and Influenza. Vaccine Acceptance, Coverage, and Mandates. JAMA 2020;epublished June 11th
• Allen. Medicaid and COVID-19At the Center of Both Health and Economic Crises. JAMA 2020;epublished June 11th
• Woloshin. False Negative Tests for SARS-CoV-2 Infection — Challenges and Implications. N Engl J Med 2020;epublished June 5th
• Weinstein. Waiting for Certainty on Covid-19 Antibody Tests — At What Cost? N Engl J Med 2020;epublished June 5th
• Chan. Putting the Public Back in Public Health — Surveying Symptoms of Covid-19. N Engl J Med 2020;epublished June 5th
• Morse. Creating Real Change at Academic Medical Centers — How Social Movements Can Be Timely Catalysts. N Engl J Med 2020;epublished June 10th
• Hardeman. Stolen Breaths. N Engl J Med 2020;epublished June 10th

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Tuesday June 9th

Research

Randomised Controlled Trials

• Full Text:  Pfortmueller. Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): a double-blind randomized controlled clinical trial. Intensive Care Med 2020;epublished June 9th

Systematic Reviews & Meta Analyses

• Full Text:  Anand. Mucoactive agents for acute respiratory failure in the critically ill: a systematic review and meta-analysis. Thorax 2020;epublished June 8th

Observational Studies

• Full Text:  Whittaker. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 2020;epublished June 8th
  • Editorial:  McCrindle. SARS-CoV-2–Related Inflammatory Multisystem Syndrome in ChildrenDifferent or Shared Etiology and Pathophysiology as Kawasaki Disease? JAMA 2020;epublished June 8th
• Full Text:  De Bus. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Med 2020;epublished June 9th

Guidelines & Position Statements

• European Resuscitation Council COVID-19 Guidelines Executive Summary. Resuscitation 2020;epublished June 8th
• Aziz. Managing ICU surge during the COVID‑19 crisis: rapid guidelines. Intensive Care Med 2020;epublished June 8th

Editorials

• Perner. How likely are COVID-19 interventions to benefit the sickest patients?. Intensive Care Med 2020;epublished June 9th

Correspondence

• Jeannet. Severe COVID-19 is associated with deep and sustained multifaceted cellular immunosuppression. Intensive Care Med 2020;epublished June 9th
  
  

Monday June 8th

Research

Systematic Review & Meta Analysis

• Full Text:  Duncan. Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis. Intensive Care Med 2020;epublished June 8th

Observational Studies

• Full Text:  Li. Extracorporeal membrane oxygenation programs for COVID-19 in China. Crit Care 2020;24:317
• Full Text:  Chernevskaya. Serum and fecal profiles of aromatic microbial metabolites reflect gut microbiota disruption in critically ill patients: a prospective observational pilot study. Crit Care 2020;24:312
• Full Text:  Wang. Multiple cross displacement amplification-a more applicable technique in detecting Pseudomonas aeruginosa of ventilator-associated pneumonia (VAP). Crit Care 2020;24:306

Protocols

• Faqihi. A pilot study of therapeutic plasma exchange for serious SARS CoV-2 disease (COVID-19): A structured summary of a randomized controlled trial study protocol. Trials 2020;21:506
• Eckhardt. Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial. Trials 2020;21:499Trials 2020;21:499
• Zhang. Efficacy and safety of Anluohuaxian in the treatment of patients with severe Coronavirus disease 2019- a multicenter, open label, randomized controlled study: a structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:495Trials 2020;21:495

Narrative Review

Clinical

• Erstad. Drug dosing in the critically ill obese patient—a focus on sedation, analgesia, and delirium. Crit Care 2020;24:315

Editorial

• Weiss. Focus on gastrointestinal system in critically ill patients. Intensive Care Med 2020;epublished June 8th
• Mohamed. Neutrophil Elastase Inhibitors: A potential prophylactic treatment option for SARS-CoV-2-induced respiratory complications?. Crit Care 2020;24:311
• Fried. How I approach weaning from venoarterial ECMO. Crit Care 2020;24:307
• Anonymous. The future of critical care: lessons from the COVID-19 crisis. Lancet Respir Med 2020;8(6):527

Commentary

• Sjöberg. Health-related quality of life after critical care—the emperor’s new clothes. Crit Care 2020;24:308
• Curley. Alone, the hardest part. Intensive Care Med 2020;epublished June 8th

Correspondence

• Painvin. Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study. Intensive Care Med 2020;epublished June 8th
• Liaudet. Blocking mineralocorticoid receptor with spironolactone may have a wide range of therapeutic actions in severe COVID-19 disease. Crit Care 2020;24:318
• Vargas. Three-step checklist for tracheostomy in critically ill COVID-19 patients. Crit Care 2020;24:316
• Bösel. Critical care physicians treating COVID-19: mind the nervous system!. Crit Care 2020;24:310
• Nagatomo. Peritoneal dialysis for COVID-19-associated acute kidney injury. Crit Care 2020;24:309

Sunday June 7th

Research

Systematic Reviews & Meta Analyses

• Full Text:  Duncan. Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis. Intensive Care Med 2020;epublished June 8th
• Full Text:  Jonas. Vaping-related Acute Parenchymal Lung Injury: A Systematic Review. Chest 2020;epublished May 19th

Observational Studies

• Full Text:  Gong. COVID-19 infection among medical staff in Wuhan: A retrospective study from a single-center. Chest 2020;epublished May 27th
• Full Text:  Sharma. Intensity of Renal Replacement Therapy and Duration of Mechanical Ventilation: Secondary Analysis of the Acute Renal Failure Trial Network Study. Chest 2020;epublished May 25th
• Full Text:  Thille. Pressure-support ventilation versus T-piece during spontaneous breathing trials before extubation among patients at high-risk of extubation failure: a post-hoc analysis of a clinical trial. Chest 2020;epublished May 18th
• Full Text:  Jehi. Individualizing risk prediction for positive COVID-19 testing: results from 11,672 patients. Chest 2020;epublished June 10th
• Full Text:  Coskinas. Changes to aspects of ongoing randomised controlled trials with fixed designs. Trials 2020;21:457

Protocols

• Malhotra. Umbilical cord blood therapy to prevent progression of COVID-19 related pneumonia: a structured summary of a study protocol for a pilot randomised controlled trial. Trials 2020;21:474
• Irvani. Effectiveness of Interferon Beta 1a, compared to Interferon Beta 1b and the usual therapeutic regimen to treat adults with moderate to severe COVID-19: structured summary of a study protocol for a randomized controlled trial. Trials 2020;21:473
• Rilinger. A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:470
• Maes. Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:468
• Kwakman. Steps to recovery: body weight-supported treadmill training for critically ill patients: a randomized controlled trial. Trials 2020;21:409Trials 2020;21:409
• Bosteels. Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial. Trials 2020;21:491Trials 2020;21:491

Guidelines

• Shang. Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China. Annals Intensive Care 2020;10:73
• Critical Care for COVID-19 Affected Patients: Position Statement of the Indian Society of Critical Care Medicine. Indian J Crit Care Med 2020;24(4):222–241
• Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report. Chest 2020;epublished June 2nd
• The Use of Bronchoscopy During the COVID-19 Pandemic. CHEST/AABIP Guideline and Expert Panel Report. Chest 2020;epublished April 30th
• Use of Tracheostomy During the COVID-19 Pandemic: CHEST/AABIP/AIPPD: Expert Panel Report. Chest 2020;epublished June 5th

Narrative Review

Clinical

• Reddy. Subphenotypes in critical care: translation into clinical practice. Lancet Respir Med 2020;8(6):631-643
• Reijnders. Immunomodulation by macrolides: therapeutic potential for critical care. Lancet Respir Med 2020;8(6):619-630
• Cappannoli. 2019 novel coronavirus: what is currently known, cardiovascular implications and management. Minerva Cardioangiologica 2020;epublished May 29th
• Infusino. Relationship between ACE-inhibitors, ARBs and SARS-CoV-2 infection: where are we? Minerva Cardioangiologica 2020;epublished May 29th
• Hendin. Better with Ultrasound: Thoracic Ultrasound. Chest 2020;epublished May 15th

Non-Clinical

• Taylor. Research skills and the data spreadsheet: A research primer for low- and middle-income countries. Afr J Emerg Med 2020;epublished June 7th

Commentary

• Ramnath. Do no harm: reaffirming the value of evidence and equipoise while minimizing cognitive bias in the COVID-19 era. Chest 2020;epublished May 28th
• Scott. What Counts as “Good” Clinical Communication in the Covid-19 Era and Beyond? Ditching Checklists for Juggling Communication Goals. Chest 2020;epublished May 27th
• de Moraes. All that Glitters isn’t Gold: Critical Care in the Time of COVID. Chest 2020;epublished May 25th
• Ramachandran. Powerless in the ICU: Perspectives from Intensive Care Units in the Face of COVID-19. Chest 2020;epublished May 23rd
• Corsello. Impact of small-N studies during a pandemic. Chest 2020;epublished June 10th
• Haas. Should we deny ICU admission to the elderly? Ethical considerations in times of COVID-19. Crit Care 2020;24:321
• Hammer. Challenges in the interpretation and application of typical imaging features of COVID-19. Lancet Respir Med 2020;8(6):534-536
• McEnery. COVID-19: Respiratory support outside the intensive care unit. Lancet Respir Med 2020;8(6):538-539
• Ingraham. Immunomodulation in COVID-19. Lancet Respir Med 2020;8(6):544-546
• De Jong. Airway management for COVID-19: a move towards universal videolaryngoscope? Lancet Respir Med 2020;8(6):555
• Vijayaraghavan. Critical Care Epidemiology and Research in the Face of a Pandemic: An Opportunity in a Crisis. Indian J Crit Care Med 2020;24(4):242–244

Correspondence

• Honore. Early latency evoked potentials can no longer be considered an infallible predictor of neurologic outcome. Crit Care 2020;24:322
• von Düring. COVID-19: desperate times call for desperate measures. Critical Care 2020;24:323
• Tralhão. Potential benefit of angiotensin II in COVID-19 patients: beyond reasonable doubt? Crit Care 2020;24:324
• Tomasa-Irriguible. Low molecular weight heparins in COVID-19 patients: beware of augmented renal clearance! Crit Care 2020;24:325
• Mahjoub. Severe Covid-19 disease: rather AVDS than ARDS? Crit Care 2020;24:327
• Arulkumaran. Use of non-invasive ventilation for patients with COVID-19: a cause for concern? Lancet Respir Med 2020;8(6):45
• Jose. COVID-19 cytokine storm: the interplay between inflammation and coagulation. Lancet Respir Med 2020;8(6):e46-e47
• Alanio. Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19. Lancet Respir Med 2020;8(6):e48-e49
• Milne. SARS-CoV-2 receptor ACE2 gene expression and RAAS inhibitors. Lancet Respir Med 2020;8(6):e50-e51
• Azoulay. A 5-point strategy for improved connection with relatives of critically ill patients with COVID-19. Lancet Respir Med 2020;8(6):e52
• Feinstein. Considerations for ventilator triage during the COVID-19 pandemic. Lancet Respir Med 2020;8(6):e53
• Kirby. Evidence mounts on the disproportionate effect of COVID-19 on ethnic minorities. Lancet Respir Med 2020;8(6):547-548

Case Reports

• Harkin. Delayed diagnosis of COVID-19 in a 34-year-old man with atypical presentation. Lancet Respir Med 2020;8(6):644-646

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Saturday June 6th

Research

Observational Studies

• Abstract:  Rowan. Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study. Am J Respir Crit Care 2020;201(11):1389–1397
  
  • Editorial:  Oishi. Equipoise and Acumen in Pediatric Acute Respiratory Distress Syndrome Research. Am J Respir Crit Care 2020;201(11):1326–1327

Guidelines

• Tripathi. Transjugular intrahepatic portosystemic stent-shunt in the management of portal hypertension. Gut 2020;69:1173-1192

Narrative Reviews

Clinical

• Breitkreutzac. Anterior neck and airway ultrasound procedures with emphasis on resuscitation plus video clips. Trends in Anaesthesia and Critical Care 2020;32:13-32
• Skrifvars. Individualized blood pressure targets during postcardiac arrest intensive care. Curr Opin Crit Care 2020;26(3):259-266
• Onigbinde. Chest Computed Tomography Findings in COVID-19 and Influenza: A Narrative Review. BioMed Research International 2020;2020:6928368
• Cho. ECMO use in COVID-19: lessons from past respiratory virus outbreaks—a narrative review. Crit Care 2020;24:301

Editorials

• Waterer. COVID-19: First Do No Harm. Am J Respir Crit Care 2020;201(11):1324–1325
• Tang. Team management in critical care units for patients with COVID-19: an experience from Hunan Province, China. Crit Care 2020;24:304

Case Report

• Zhang. An Asymptomatic Patient with COVID-19. Am J Respir Crit Care 2020;201(11):1428–1429

Correspondence

• Huang. SARS-CoV-2 Viral Load in Clinical Samples from Critically Ill Patients. Am J Respir Crit Care 2020;201(11):1435–1438
• Tsolaki. PEEP levels in COVID-19 pneumonia. Crit Care 2020;24:303

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Friday June 5th

Research

Systematic Reviews & Meta Analyses

• Full Text:  Meyhoff. Lower vs Higher Fluid Volumes During Initial Management of Sepsis. A Systematic Review With Meta-Analysis and Trial Sequential Analysis. Chest 2020;157(6):1478–1496
  
  • Editorial:  Ferguson. Fluid Volume Trials in Sepsis. An Arid Landscape. Chest 2020;157(6):1404-1404
• Full Text:  Silberberg. Recommendations for fluid management of adults with sepsis in sub-Saharan Africa: a systematic review of guidelines. Crit Care 2020;24:286

Observational Studies

• Full Text:  Simonson. 5-year Follow up After MSC-based Treatment of Severe Acute Respiratory Distress Syndrome. Am J Respir Crit Care 2020;epublished June 5th
• Abstract:  Duggal. Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS. Insights From the LUNG SAFE Study. Chest 2020;157(6):1497–1505
  
  • Editorial:  Qadir. Adjunctive Therapies in ARDS. The Disconnect Between Clinical Trials and Clinical Practice. Chest 2020;157(6):1405–1406
• Full Text:  MacMurdo. e-Cigarette or Vaping Product Use-Associated Lung Injury. Clinical, Radiologic, and Pathologic Findings of 15 Cases. Chest 2020;157(6):e181–e187
• Full Text:  Tharakan. Body temperature correlates with mortality in COVID-19 patients. Crit Care 2020;24:298
• Full Text:  Becher. Procedural volume and outcomes in patients undergoing VA-ECMO support. Crit Care 2020;24:291
• Full Text:  Pierrakos. Biomarkers of sepsis: time for a reappraisal. Crit Care 2020;24:287

News

• Statement from the Chief Investigators of the Randomised Evaluation of COVid-19 thERapY (RECOVERY) Trial on hydroxychloroquine

Narrative Reviews

Clinical

• Lal. Artificial intelligence and computer simulation models in critical illness. World J Crit Care Med 2020;9(2):13-19
• Cho. ECMO use in COVID-19: lessons from past respiratory virus outbreaks—a narrative review. Crit Care 2020;24:301
• Sullivan. In-hospital airway management of COVID-19 patients. Crit Care 2020;24:292

Editorials

• Marra. How COVID-19 pandemic changed our communication with families: losing nonverbal cues. Crit Care 2020;24:297
• François. The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients. Crit Care 2020;24:289

Commentary

• Horton. Offline: COVID-19 and the ethics of memory. Lancet 2020;395(10239):1750
• Mullard. COVID-19 vaccine development pipeline gears up. Lancet 2020;395(10239):1751-1752
• Cecconi. Ten things we learned about COVID-19. Intensive Care Med 2020;epublished June 5th
• Russell. Independent Clinical Criteria in Medicine. The Unusual Case of Septic Shock. Chest 2020;157(6):1418–1419
• Hasan. Preparing for the COVID-19 Pandemic. Our Experience in New York. Chest 2020;157(6):1420–1422
• Speth. Angiotensin II administration to COVID-19 patients is not advisable. Crit Care 2020;24:296
• Azoulay. Admission decisions to intensive care units in the context of the major COVID-19 outbreak: local guidance from the COVID-19 Paris-region area. Crit Care 2020;24:293

Case Reports

• Ahmed. Neuropathy, encephalopathy, status epilepticus, and acute intermittent porphyria. Lancet 2020;395(10239):E101
• Belloli. A 53-Year-Old Woman With Dyspnea, Wheezing, and Irreversible Airway Obstruction. Chest 2020;157(6):e189–e192
• Agrawal. A Pregnant Woman Presenting With Progressively Worsening Dyspnea and Pneumothorax. Chest 2020;157(6):e193–e196
• Li. A 52-Year-Old Man With Cough, Dyspnea, and Diffuse Parenchymal Lung Disease for 5 Years. Chest 2020;157(6):e197–e201
• Bai. A Right Atrial Finding in an IV Drug User in His Late 40s. Chest 2020;157(6):e203–e205

Correspondence

• Zangrillo. Learning from mistakes during the pandemic: the Lombardy lesson. Intensive Care Med 2020;epublished June 5th
• Tonna. Mechanical power and driving pressure as predictors of mortality among patients with ARDS. Intensive Care Med 2020;epublished June 5th
• Camporota. From phenotypes to black holes… and back. Intensive Care Med 2020;epublished June 5th
  • Rajendram. Rethinking the respiratory paradigm of COVID-19: a ‘hole’ in the argument. Intensive Care Med 2020;epublished June 2nd
• Russotto. Preoxygenation of Critically Ill Patients With Acute Hypoxemic Respiratory Failure. Chest 2020;157(6):1684–1685
• Agrawal. Response to Airway Management in Critically Ill Patients. Don’t Forget the Bronchoscope! Chest 2020;157(6):1685–1686
  
  • Scott. Response. Chest 2020;157(6):1686–1687
• Tsolaki. PEEP levels in COVID-19 pneumonia. Crit Care 2020;24:303
• Ricci. COVID-19—immunity from prosecution for physicians forced to allocate scarce resources: the Italian perspective. Crit Care 2020;24:295
• Honore. Detecting influenza-associated pulmonary aspergillosis by determination of galactomannan in broncho-alveolar lavage fluid and in serum: should we add (1,3)-beta-D-glucan to improve efficacy. Crit Care 2020;24:294

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Thursday June 4th

Research

Retractions

• Mehra. Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621. N Engl J Med 2020;epublished June 4th
• Mehra. Retraction: "Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis". Lancet 2020;epublished June 4th

Systematic Review & Meta Analyses

• Full Text:  Ferreyro. Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory FailureA Systematic Review and Meta-analysis. JAMA 2020;epublished June 4th
  • Editorial:  Patel. Alternatives to Invasive Ventilation in the COVID-19 Pandemic. JAMA 2020;epublished June 4th
• Full Text:  Quah. Mortality rates of patients with COVID-19 in the intensive care unit: a systematic review of the emerging literature. Crit Care 2020;24:285

Observational Studies

• Abstract:  Viglianti. Hospital-level variation in the development of persistent critical illness. Intensive Care Med 2020;epublished June 4th
• Full Text:  Chau. The natural history and transmission potential of asymptomatic SARS-CoV-2 infection. Clinical Infectious Diseases 2020;epublished June 4th

Narrative Review

Clinical

• Li. Active case finding with case management: the key to tackling the COVID-19 pandemic. Lancet 2020;epublished June 4th

Commentary

• Parks. How to Discover Antiviral Drugs Quickly. N Engl J Med 2020;382;23:2261-2264
• Hedenstierna. Airway closure, more harmful than atelectasis in intensive care? Intensive Care Med 2020;epublished June 4th
• Rocco. What have we learned from animal models of ventilator-induced lung injury?. Intensive Care Med 2020;epublished June 4th

Correspondence

• von Weyhern. Early evidence of pronounced brain involvement in fatal COVID-19 outcomes. Lancet 2020;epublished June 4th
• Fernando. A way toward ventilator-associated lower respiratory tract infection research: reply. Intensive Care Med 2020;epublished June 4th

Podcast

• Rubin. Audio Interview: Diagnosis and Early Treatment of Covid-19. N Engl J Med 2020; 382:e103

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Wednesday June 3rd

Research

Randomised Controlled Trials

• Full Text: Li. Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19A Randomized Clinical Trial. JAMA 2020;epublished June 3rd
  
  • Editorial:  Casadevall. A Randomized Trial of Convalescent Plasma for COVID-19—Potentially Hopeful Signals. JAMA 2020;epublished June 3rd
• Full Text:  Boulware. A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19. N Engl J Med 2020;epublished June 3rd
  
  • Editorial:  Cohen. A Randomized Trial of Convalescent Plasma for COVID-19—Potentially Hopeful Signals. N Engl J Med 2020;epublished June 3rd

Systematic Reviews & Meta Analyses

• Full Text:  Abdallah. Systematic review with meta‐analysis: liver transplant provides survival benefit in patients with acute on chronic liver failure. Aliment Pharmacol Ther 2020;epublished June 3rd

Observational Studies

• Full Text:  Parri. Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research Networks. Eur J Pediatr 2020;epublished June 3rd
• Full Text:  Moseby-Knappe. Performance of a guideline-recommended algorithm for prognostication of poor neurological outcome after cardiac arrest. Intensive Care Med 2020;epublished June 3rd

Protocols

• Gorman. Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial. Trials 2020;21(1):462

Expression of Concern

• The Lancet Editors. Expression of concern: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis. Lancet 2020;epublished June 3rd

Commentary

• Beach. Of Heroes and Cowards. N Engl J Med 2020;epublished June 3rd
• Pickkers. COVID-19: 10 things I wished I’d known some months ago. Intensive Care Med 2020;epublished June 3rd
• McBride. Championing survival: connecting the unknown network of responders to address out-of-hospital cardiac arrest. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2020;28:

Correspondence

• Klompas. Universal Masking in the Covid-19 Era. N Engl J Med 2020.epublished June 3rd
• Monteiro. Histological–ultrasonographical correlation of pulmonary involvement in severe COVID-19. Intensive Care Med 2020;epublished June 3rd

Video

• Offit. Coronavirus Vaccine Development. JAMA 2020;epublished June 3rd

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Tuesday June 2nd

Research

Randomised Controlled Trial

• Full Text:  von Dach. Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative BacteremiaA Randomized Clinical Trial. JAMA 2020;323(21):2160-2169
• Full Text:  Wang. Effects of a single dose of vitamin D in septic children: a randomized, double-blinded, controlled trial. J Int Med Res 2020;48(5):1–11

Observational Studies

• Abstract:  Man. Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke. JAMA 2020;323(21):2170-2184
• Editorial:  Muth. Long-term Outcomes After Thrombolytic Therapy for Acute Ischemic Stroke. JAMA 2020;323(21):2184-2185

Expression of Concern

• Rubin. Expression of Concern: Mehra MR et al. Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med 2020;epublished June 2nd

Editorial

• Shrestha. Precision medicine for COVID-19: a call for better clinical trials. Crit Care 2020;24:282
• Cour. Cyclosporine A: a valid candidate to treat COVID-19 patients with acute respiratory failure? Crit Care 2020;24:276

Correspondence

• Monneret. Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients. Intensive Care Med 2020;epublished June 2nd
• Fraissé. Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study. Crit Care 2020;24:275
• Hékimian. Severe pulmonary embolism in COVID-19 patients: a call for increased awareness. Crit Care 2020;24:274 

Video

• Coronavirus Q&A With Anthony Fauci, MD. JAMA 2020;epublished June 2nd

News

• Voelker. Hemodialysis Device for Very Small Pediatric Patients. JAMA 2020;323(21):2122

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Monday June 1st

Research

Randomised Controlled Trials

• Abstract:  Brophy. Bayesian Interpretation of the EXCEL Trial and Other Randomized Clinical Trials of Left Main Coronary Artery Revascularization. JAMA Intern Med 2020;epublished June 1st
• Full Text:  Borges. Duration of antibiotic therapy in critically ill patients: a randomized controlled trial of a clinical and C-reactive protein-based protocol versus an evidence-based best practice strategy without biomarkers. Crit Care 2020;24:281

Systematic Reviews & Meta Analyses

• Full Text:  Chu. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet 2020;epublished June 1st

Observational Studies

• Full Text:  Hall. Fluid removal associates with better outcomes in critically ill patients receiving continuous renal replacement therapy: a cohort study. Crit Care 2020;24:279

Narrative reviews

Clinical

• Hon. Overview: The history and pediatric perspectives of severe acute respiratory syndromes: Novel or just like SARS. Pediatr Pulmonol 2020;epublished June 1st
• Adelman. The gut microbiome’s role in the development, maintenance, and outcomes of sepsis. Crit Care 2020;24:278

Editorials

• Bos. The perils of premature phenotyping in COVID: a call for caution. Eur Respir J 2020;epublished June 1st

Commentary

• Nardell. Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection. JAMA 2020;epublished June 1st

Correspondence

• Honore. Endovascular cooling is superior to surface cooling in terms of effectiveness by improving the neurological prognosis, but what about the safety?. Crit Care 2020;24:277

News

• Voelker. Hemodialysis Device for Very Small Pediatric Patients. JAMA 2020;323(21):2122

Sunday May 31st

Narrative Reviews

Clinical

• Habimana. Sepsis-induced cardiac dysfunction: a review of pathophysiology. Acute Crit Care 2020;35(2):57-66
• Mushambi. Anticipated difficult airway during obstetric general anaesthesia: narrative literature review and management recommendations. Anaesthesia 2020;75(7):9555-961
  
  • Editorial:  McGuire. Planning the obstetric airway. Anaesthesia 2020;75(7):852-855
• Cook. Personal protective equipment during the coronavirus disease (COVID) 2019 pandemic – a narrative review. Anaesthesia 2020;75(7):920-927
• Carenzo. Hospital surge capacity in a tertiary emergency referral centre during the COVID ‐19 outbreak in Italy. Anaesthesia 2020;75(7):928-934
• Sorbello. The Italian coronavirus disease 2019 outbreak: recommendations from clinical practice. Anaesthesia 2020;75(6):724-732
• Al-Ani. Thrombosis Risk Associated With COVID-19 Infection. A Scoping Review. Thromb Res 2020;192:152-160

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Saturday May 30th

Research

Randomised Controlled Trials

• Full Text:  Deng. A pilot randomised controlled trial of the management of systolic blood pressure during endovascular thrombectomy for acute ischaemic stroke. Anaesthesia 2020;75(6):739-746
  
  • Editorial:  Wiles. Is blood pressure maintenance more important than type of anaesthesia for patients undergoing mechanical thrombectomy after ischaemic stoke? Anaesthesia 2020;75(6):716-719
• Abstract:  Le Guen. Reversal of neuromuscular blockade with sugammadex during continuous administration of anaesthetic agents: a double‐blind randomised crossover study using the bispectral index. Anaesthesia 2020;75(5):583-59.

Guidelines & Position Statements

• Consensus guidelines for managing the airway in patients with COVID ‐19. Anaesthesia 2020;75(6):785-799

Correspondence

• Zhao. COVID-19 pneumonia: phenotype assessment requires bedside tools. Crit Care 2020;24:272

Editorials

• Lyons. The use of high‐flow nasal oxygen in COVID ‐19. Anaesthesia 2020;75(7):843-847
• Chrimes. Welcome to the era of universal airway management. Anaesthesia 2020;75(6):711-715
• Kelly. Improving resilience in anaesthesia and intensive care medicine – learning lessons from the military. Anaesthesia 2020;75(6):720-723

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Friday May 29th

Research

Randomised Controlled Trials

• Abstract:  Francois. Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial. Intensive Care Med 2020;epublished May 28th

Systematic Reviews & Meta Analyses

• Full Text:  Qu. Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome. Stem Cells Transl Med 2020;epublished May 29th

Observational Studies

• Full Text:  COVIDSurg Collaborative. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet 2020;epublished May 29th
  • Commentary:  Myles. Mitigating the risks of surgery during the COVID-19 pandemic. Lancet 2020;epublished May 29th
• Full Text:  Begley. The aerosol box for intubation in coronavirus disease 2019 patients: an in‐situ simulation crossover study. Anaesthesia 2020;epublished May 12th

Narrative Reviews

Clinical

• Zubair. Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019. A Review. JAMA Neurol 2020;epublished May 29th

Commentaries

• Vassilakopoulos. What’s new about pulmonary hyperinflation in mechanically ventilated critical patients. Intensive Care Med 2020;epublished May 29th

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Thursday May 28th

Guidelines

• Purvis. Prone position ventilation in non-intubated, spontaneously ventilating patients: New guidance from the Intensive Care Society (UK) and existing evidence. JICS 2020;epublished May 28th

Commentaries

• Fleming. Conducting Clinical Research During the COVID-19 Pandemic. Protecting Scientific Integrity. JAMA 2020;epublished May 28th
• Lee. The starting line for COVID-19 vaccine development. Lancet 2020;epublished May 28th
• Pittiruti. Recommendations for the use of vascular access in the COVID-19 patients: an Italian perspective. Crit Care 2020;24:269

Podcast

• Rubin. Audio Interview: Audio Interview: New Data on Remdesivir in Covid-19. N Engl J Med 2020;382:e94

Correspondence

• Various. Allocating Medical Resources in the Time of Covid-19. N Engl J Med 2020;382:e79
• Kok. Recognizing and supporting morally injured ICU professionals during the COVID-19 pandemic. Intensive Care Med 2020;epublished May 28th
• Honore. The causal link between hyperchloremia and acute kidney injury is yet to be conclusively established: we are not sure. Crit Care 2020;24:271
• Lal. Physiologic approach to diuresis in de-resuscitation phase in intensive care. Crit Care 2020;24:270

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Wednesday May 27th

Research

Randomised Controlled Trials

• Full Text:  Goldman. Remdesivir for 5 or 10 Days in Patients with Severe Covid-19. N Engl J Med 2020;epublished May 27th
  • Editorial:  Dolin. Remdesivir — An Important First Step. N Engl J Med 2020;epublished May 27th
• Full Text:  Cao. Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial, J Allergy Clin Immunol 2020;epublished May 26th

Observational Studies

• Full Text:  López-Fernández. Prognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study. Intensive Care Med 2020;epublished May 25th

Narrative Reviews

Clinical

• Al-Ani. Thrombosis Risk Associated With COVID-19 Infection. A Scoping Review. Thromb Res 2020;192:152-160
• Tolles. Modeling Epidemics With Compartmental Models. JAMA 2020;epublished May 27th

Editorials

• Einav. Focus on better care and ethics: Are medical ethics lagging behind the development of new medical technologies? Intensive Care Med 2020;epublished May 27th

Commentaries

• Jacobsen. Case 19-2020: A 74-Year-Old Man with Acute Respiratory Failure and Unclear Goals of Care. N Engl J Med 2020;epublished May 27th
• Brener. Where Do the Children Play? N Engl J Med 2020;epublished May 27th

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Tuesday May 26th

Editorials

• Verdonk. How machine learning could be used in clinical practice during an epidemic. Crit Care 2020;24:265

Commentaries

• Trogen. Adverse Consequences of Rushing a SARS-CoV-2 VaccineImplications for Public Trust. JAMA 2020;epublished May 26th
• de Lange. ICU beds: less is more? No Intensive Care Med 2020;epublished May 26th

Correspondence

• Various. More on Neurologic Features in Severe SARS-CoV-2 Infection. N Engl J Med 2020;epublished May 26th
• Kox. COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients. Crit Care 2020;24:263
• Honore. Acyclovir for ventilator-associated pneumonia refractory to antibiotics and with high viral herpes simplex load: we are not sure. Crit Care 2020;24:262
• Sanfilippo. The importance of a “socially responsible” approach during COVID-19: the invisible heroes of science in Italy. Crit Care 2020;24:261

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Monday May 25th

Editorial

• De Jong. Focus on noninvasive respiratory support before and after mechanical ventilation in patients with acute respiratory failure. Intensive Care Med 2020;epublished May 25th
• Gattinoni. The baby lung and the COVID-19 era. Intensive Care Med 2020;epublished May 25th

Commentaries

• Honigsbaum. Revisiting the 1957 and 1968 influenza pandemics. Lancet 2020;epublished May 25th
• Brindley. Pandemic airway management: A cognitive aid to increase safety and team cohesion during intubation, donning, and doffing. JICS 2020;epublished May 25th

Correspondence

• Tang. Caution against corticosteroid-based COVID-19 treatment. Lancet 2020;395(10239):1759-1760
• Auriemma. The attributable mortality of acute respiratory distress syndrome. Intensive Care Med 2020;epublished May 25th
• Yang. Lung ultrasonography versus chest CT in COVID-19 pneumonia: a two-centered retrospective comparison study from China. Intensive Care Med 2020;epublished May 25th
• Bellelli. Frailty index predicts poor outcome in COVID-19 patients. Intensive Care Med 2020;epublished May 25th
• Yan. Duration of SARS-CoV-2 viral RNA in asymptomatic carriers. Crit Care 2020;24:245
• de Koning. Nutritional therapy in patients with sepsis: is less really more?. Crit Care 2020;24:254
• Gao. Do critically ill patients with AKI benefit from furosemide? Further real-word evidence from a large multi-center database. Crit Care 2020;24:253

Sunday May 24th

Research

Randomised Controlled Trials

• Full Text:  Van Dyck. Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study. Crit Care 2020;24:249

Observational Studies

• Full Text:  Coppola. Effect of mechanical power on intensive care mortality in ARDS patients. Crit Care 2020;24:246
• Full Text:  Knaak. Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore. Crit Care 2020;24:244

Narrative Reviews

Clinical

• Brezeanu. Anaesthesia for Liver Transplantation: An Update. The Journal of Critical Care Medicine 2020;6(2):91-100
• Smit. Delirium in the ICU – A structured review of promising diagnostic and therapeutic approaches: Next steps in ICU delirium. Neth J Crit Care May 2020;28(3):126-133
• Lampridis. The insidious presentation and challenging management of esophageal perforation following diagnostic and therapeutic interventions. J Thorac Dis 2020;12(5):2724-2734
• Skaria. Path to precision: prevention of post-operative atrial fibrillation. J Thorac Dis 2020;12(5):2735-2746
• Cohen. Defining and managing patients with non-ST-elevation myocardial infarction: Sorting through type 1 vs other types. Clin Cardiol.2020;43:242–250

Guidelines & Position Statements

• Society for Advanced Bronchoscopy Consensus Statement and Guidelines for bronchoscopy and airway management amid the COVID-19 pandemic. J Thorac Dis 2020;12(5):1781-1798

Editorials

• Balasa. Therapeutic Plasma Exchange: An Indispensable Therapy for Severe Neurological. The Journal of Critical Care Medicine 2020;6(2):91-100

Commentaries

• Szawarski. Classic cases revisited – Tony Nicklinson and the question of dignity. JICS 2020;21(2):174-178
• McKenna. Reconsidering critical illness as an uncharacterised acquired mitochondrial disorder. JICS 2020;21(2):102-104

Case Reports

• Oh. Right ventricular assist device with an oxygenator using extracorporeal membrane oxygenation as a bridge to lung transplantation in a patient with severe respiratory failure and right heart decompensation. Acute Crit Care 2020;35(2):117-121
• Hensher. High-Dose Insulin Euglycemic Therapy in the Treatment of a Massive Caffeine Overdose. Chest 2020;157(5):e145–e149
• Koslow. A 48-Year-Old South African Woman with Rheumatoid Arthritis and Lung Nodules. Chest 2020;157(5):e151–e155
• Farrah. A 54-Year-Old Woman With Shortness of Breath After Nephrolithotomy. Chest 2020;157(5):e157–e160
• Tseng. A 75-Year-Old Man With Organizing Pneumonia Presenting With Worsening Dyspnea. Chest 2020;157(5):e161–e164
• Yamamoto. A 71-Year-Old Man With Dyspnea and Cough During Chemotherapy. Chest 2020;157(5):e165–e171
• Rublee. A Case for the Use of Transesophageal Echocardiography in the ED Treatment of Cardiac Arrest. Chest 2020;157(5):e173–e176
• Mohamed. A Spontaneously Resolving Pericardial Effusion During CPR. Chest 2020;157(5):e177–e180

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Saturday May 23rd

Research

Randomised Controlled Trials

• Full Text:  Hung. Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet 2020;395(10238):1695-1704
  
  • Commentary:  Shalhoub. Interferon beta-1b for COVID-19. Lancet 2020;395(10238):1670-1671

Systematic Reviews & Meta Analyses

• Full Text:  van der Zee. A systematic review of biomarkers multivariately associated with acute respiratory distress syndrome development and mortality. Crit Care 2020;24:243

Observational Studies

• Full Text:  de Abajo. Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study. Lancet 2020;395(10238):1705-1714
  
  • Commentary:  Williams. Hypertension, renin–angiotensin–aldosterone system inhibition, and COVID-19. Lancet 2020;395(10238):1671-1673
• Full Text:  Silversides. Fluid management and deresuscitation practices: A survey of critical care physicians. JICS 2020;21(2):111-118
• Full Text:  Miroz. Neurological Pupil index for Early Prognostication After Venoarterial Extracorporeal Membrane Oxygenation. Chest 2020;157(5):1167-1174
  
  • Editorial:  Ong. Quantitative Pupillometry. A Prognostic Tool for Cardiac Arrest and Refractory Cardiogenic Shock Undergoing VA-ECMO Therapy. Chest 2020;157(5):1049-1050

Correspondence

• Mannucci. Saturation of critical care capacity and mortality in patients with thenovel coronavirus (COVID-19) in Italy. Trends in Anaesthesia and Critical Care 2020;epublished May 23rd
• Patel. Confirm, Don’t Conform Toward Thrombolysis in Acute Pulmonary Embolism in Out-of-Hospital Cardiac Arrest. Chest 2020;157(5):1396–1397
  
  • Javaudin. Reply. Chest 2020;157(5):1397-1398

Case Reports

• Jansen. Tension enterothorax: a rare differential diagnosis of progressive dyspnea. Intensive Care Med 2020;epublished May 23rd

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Friday May 22nd

Research

Randomised Controlled Trials

• Full Text:  Beigel. Remdesivir for the Treatment of Covid-19 — Preliminary Report. N Engl J Med 2020;epublished May 22nd

Observational Studies

• Full Text:  Zhu. Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial. Lancet 2020;epublished May 22nd

Commentaries

• del Rio. Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response. JAMA 2020;epublished May 22nd
• Strasser. A history of the medical mask and the rise of throwaway culture. Lancet 2020;epublished May 22nd

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Thursday May 21st

Research

Systematic Reviews & Meta Analyses

• Full Text:  Elias. Experiences of Newly Qualified Nurses in Critical Care: A qualitative systematic review. JICS 2020;epublished May 21st

Observational Studies

• Full Text:  Schaller. Postmortem Examination of Patients With COVID-19. JAMA 2020;epublished May 21st
• Full Text:  Ackermann. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N Engl J Med 2020;epublished May 21st
  
  • Editorial:  Hariri. Covid-19, Angiogenesis, and ARDS Endotypes. N Engl J Med 2020;epublished May 21st

Commentaries

• Klompas. Universal Masking in Hospitals in the Covid-19 Era. N Engl J Med 2020;382:e63

Podcast

• Collins. The NIH Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Initiative. JAMA 2020;epublished May 21st
• Rubin. Audio Interview: Capitalizing on Immune Responses to Covid-19. N Engl J Med 2020;382:e93

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Wednesday May 20th

Commentary

• Earnest. On Becoming a Plague Doctor. N Engl J Med 2020;epublished May 20th
• Thomas. Pandemic as Teacher — Forcing Clinicians to Inhabit the Experience of Serious Illness. N Engl J Med 2020;epublished May 20th

Correspondence

• Riphagen. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet 2020;395(10237):1607-1608
• Helms. Prothrombotic phenotype in COVID-19 severe patients. Intensive Care Med 2020;epublished May 20th
  • Rech. Incidence of pulmonary embolism in patients with COVID-19. Intensive Care Med 2020;epublished May 20th

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Tuesday May 19th

Research

Systematic Reviews & Meta Analyses

• Full Text:  Kuo. Thromboembolic and bleeding risk of periprocedural bridging anticoagulation: Asystematic review and meta-analysis. Clinical Cardiology 2020;43:441–449
• Full Text:  Y-Hassan. Clinical features, complications, and outcomes of exogenous andendogenous catecholamine-triggered Takotsubo syndrome: A systematic review and meta-analysis of 156 published cases. Clinical Cardiology 2020;43:459–467
• Full Text:  Bauer. Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019— results from a systematic review and meta-analysis. Crit Care 2020;24:239

Observational Studies

• Full Text:  Cummings. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet 2020;395(10239):1763-1770
  
  • Commentary:  Grasselli. Critically ill patients with COVID-19 in New York City. Lancet 2020;395(10239):1740-1741

Narrative Reviews

Clinical

• Wright. Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma. Open Forum Infectious Diseases 2020;7(5):ofaa132
• Russell. Preeclampsia and the anaesthesiologist: current management. Curr Opinion in Anaesthesiology 2020;33(3):305-310
• van der Schoot. Acute myocardial infarction in adolescents: reappraisal of underlying mechanisms. Netherlands Heart Journal 2020;28:301–308

Editorials

• Gaudry. Interpreting trials on renal replacement therapy initiation: beware of methodologic issues. Crit Care 2020;24:240

Commentaries

• Solomon. Covid-19 Crisis Triage — Optimizing Health Outcomes and Disability Rights. N Engl J Med 2020;epublished May 19th
• Mello. Respecting Disability Rights — Toward Improved Crisis Standards of Care. N Engl J Med 2020;epublished May 19th
• Ronco. Management of acute kidney injury in patients with COVID-19. Lancet Respir Med 2020;epublished May 14th

Correspondence

• Various. Renin–Angiotensin–Aldosterone System Inhibitors in Covid-19. N Engl J Med 2020;epublished May 19th
• Solomon. The Covid-19 Pandemic and the Incidence of Acute Myocardial Infarction. N Engl J Med 2020;epublished May 19th

Case Reports

• Lacroix. SARS-CoV-2 pulmonary infection revealed by subcutaneous emphysema and pneumomediastinum. Intensive Care Med 2020;epublished May 19th

Video

• Oreta. Personal Protective Equipment and Covid-19. N Engl J Med 2020;epublished May 19th
  

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Monday May 18th

Research

Observational Studies

• Full Text:  Sood. Seroprevalence of SARS-CoV-2–Specific Antibodies Among Adults in Los Angeles County, California, on April 10-11, 2020. JAMA 2020;epublished May 18th
• Full Text:  Verdoni. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet 2020;395(10239):1771-1778
  • Commentary:  Viner. Kawasaki-like disease: emerging complication during the COVID-19 pandemic. Lancet 2020;395(10239):1741-1743
• Full Text:  Mirouse. Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study. Crit Care 2020;24:231

Editorials

• Lotz. Unconventional approaches to mechanical ventilation—step-by-step through the COVID-19 crisis. Crit Care 2020;24:233

Commentaries

• Rello. Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers. Eur Respir J 2020;55(5):2001028
• DeRoo. Planning for a COVID-19 Vaccination Program. JAMA 2020;epublished May 18th
• Collins. Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)An Unprecedented Partnership for Unprecedented Times. JAMA 2020;epublished May 18th
• Sittig. COVID-19 and the Need for a National Health Information Technology Infrastructure. JAMA 2020;epublished May 18th

Case Reports

• Azouz. Systemic arterial thrombosis and acute mesenteric ischemia in a patient with COVID-19. Intensive Care Med 2020;epublished May 18th

Correspondence

• Tee. Contrast-enhanced ultrasound (CEUS) of the lung reveals multiple areas of microthrombi in a COVID-19 patient. Intensive Care Med 2020;epublished May 18th
• Jain. Stages or phenotypes? A critical look at COVID-19 pathophysiology. Intensive Care Med 2020;epublished May 18th

Sunday May 17th

Research

Randomised Controlled Trials

• Full Text:  Hadfield. Neurally adjusted ventilatory assist versus pressure support ventilation: a randomized controlled feasibility trial performed in patients at risk of prolonged mechanical ventilation. Critical Care 2020;24:220
• Full Text::  Shalhoub. Graduated compression stockings as adjuvant to pharmaco-thromboprophylaxis in elective surgical patients (GAPS study): randomised controlled trial. BMJ 2020;369:m1309BMJ 2020;369:m1309

Observational Studies

• Full Text:  Mesquida. Thenar oxygen saturation (StO2) alterations during a spontaneous breathing trial predict extubation failure. Ann Intensive Care 2020;10:54
• Full Text:  de Montmollin. One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study. Ann Intensive Care 2020;10:53
• Abstract:  Goudelin. Left ventricular overloading identified by critical care echocardiography is key in weaning-induced pulmonary edema. Intensive Care Med 2020;epublished May 6th
• Abstract:  Prieto-Palomino. Improvement of quality of life (QOL) between 1 and 3-4 years after traumatic brain injury (TBI) in ICU patients. Acta Neurochir 2020;epublished May 13th
• Full Text:  Sartini. Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit. JAMA 2020;epublished May 15th
• Full Text:  Elharrar. Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure. JAMA 2020;epublished May 15th
  • Editorial:  Telias. Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19? JAMA 2020;epublished May 15th
• Full Text:  Geleris. Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19. N Engl J Med 2020;epublished May 7th
• Editorial:  Rubin. The Urgency of Care during the Covid-19 Pandemic — Learning as We Go. N Engl J Med 2020;epublished May 7th
• Full Text:  Piccininni. Use of all cause mortality to quantify the consequences of covid-19 in Nembro, Lombardy: descriptive study. BMJ 2020;369:m1835
• Full Text:  Mahévas. Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data. BMJ 2020;369:m1844 
• Full Text:  Tang. Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial. BMJ 2020;369:m1849
• Full Text:  Pan. Lung Recruitability in COVID-19–associated Acute Respiratory Distress Syndrome: A Single-Center Observational Study. Am J Respir Crit Care Med 2020;201(10):1294–1297
• Full Text:  Liu. Ventilatory Ratio in Hypercapnic Mechanically Ventilated Patients with COVID-19–associated Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2020;201(10):1297–1299
• Full Text:  Ren. Clinical features and development of sepsis in patients infected with SARS-CoV-2: a retrospective analysis of 150 cases outside Wuhan, China. Intensive Care Med 2020;epublished May 15th
• Full Text:  Hamiel. SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults. JAMA 2020;epublished May 13th
• Full Text:  Rosenberg. Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State. JAMA 2020;epublished May 11th
  
  • Editorial:  Bonow. Hydroxychloroquine, Coronavirus Disease 2019, and QT Prolongation. JAMA Cardiol 2020;epublished May 1st
• Full Text:  Hains. Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit. JAMA 2020;epublished May 14th
• Full Text:  Shekerdemian. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr 2020;epublished May 11th
• Full Text:  Zangrillo. Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series. Critical Care 2020;24:227
• Full Text:  Zdolsek. Plasma volume expansion and capillary leakage of 20% albumin in burned patients and volunteers. Critical Care 2020;24:191
• Full Text:  Ramanan. Does asymmetry in patient recruitment in large critical care trials follow the Pareto principle? Trials volume 21, Article number: 378 (2020)

Cochrane Reviews

• Valk. Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review. Cochrane Database Syst Rev 2020;5:CD013600

Protocols

• Lopes. Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Am Heart J 2020;epublished May 13th
• Kwakman. Steps to recovery: body weight-supported treadmill training for critically ill patients: a randomized controlled trial. Trials 2020;21:409 

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Saturday May 16th

News

• Mahase. Covid-19: Cases of inflammatory syndrome in children surge after urgent alert. BMJ 2020;369:m1990BMJ 2020;369:m1990
• Dyer. Covid-19: Trump fumes as adviser speaks out against lifting of US lockdowns. BMJ 2020;369:m1993
• Rubin. Global Effort to Collect Data on Ventilated Patients With COVID-19. JAMA 2020;epublished May 13th

Correspondence

• Gattinoni. COVID-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2020;201(10):1299–1300
• Huttner. 2019 Community-acquired Pneumonia Treatment Guidelines: There Is a Need for a Change toward More Parsimonious Antibiotic Use. Am J Respir Crit Care Med 2020;201(10):1315–1316
• Metlay. Reply to Huttner et al.: 2019 Community-acquired Pneumonia Treatment Guidelines: There Is a Need for a Change toward More Parsimonious Antibiotic Use. Am J Respir Crit Care Med 2020;201(10):1316–1317
• Ison. Emergency Use Authorization of Remdesivir. The Need for a Transparent Distribution Process. JAMA 2020;epublished May 14th
• Honore. Therapeutic plasma exchange as a routine therapy in septic shock and as an experimental treatment for COVID-19: we are not sure. Critical Care 2020;24:226
• Chase. Safe doubling of ventilator capacity: a last resort proposal for last resorts. Critical Care 2020;24:222
• Garcia. Students Supporting Critical Care – A contention plan to prevent the decompensation of ICUs in the COVID-19 pandemic:Translating Bjorn Ibsens’ polio-lessons to modern times. Critical Care 2020;24:211
• Pantos. Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial. Critical Care 2020;24:209
• Hassanian-Moghaddam. COVID-19 pandemic, healthcare providers’ contamination and death: an international view. Critical Care 2020;24:208
• Honore. Austrian recommendations for best clinical practice in case of haemorrhagic traumatic brain injury under platelet inhibitors or non-vitamin K antagonist oral anticoagulants: an additional therapeutic option to consider. Critical Care 2020;24:204
• Frippiat. Meropenem: continuous or extended infusion? Critical Care 2020;24:192
• Yager. Repurposing a Pediatric ICU for Adults. N Engl J Med 2020;epublished May 15th

Case Reports

• Sise. Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury. N Engl J Med 2020;epublished May 13th
• Creel-Bulos. Acute Cor Pulmonale in Critically Ill Patients with Covid-19. N Engl J Med 2020;epublished May 6th
• Hains. Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit. JAMA 2020;epublished May 14th

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Friday May 15th

Guidelines & Position Statements

• Cook. Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients. Neurocrit Care 2020;32:647–666
• Coccolini. Liver trauma: WSES 2020 guidelines. World J Emerg Surg 2020;15:24

Commentaries

• Joly. Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19. Intensive Care Med 2020;epublished May 15th
• Angulo. Reopening Society and the Need for Real-Time Assessment of COVID-19 at the Community Level. JAMA 2020;epublished May 15th
• Schneider. Failing the Test — The Tragic Data Gap Undermining the U.S. Pandemic Response. N Engl J Med 2020;epublished May 15th
• Holmdahl. Wrong but Useful — What Covid-19 Epidemiologic Models Can and Cannot Tell Us. N Engl J Med 2020;epublished May 15th
• Joly. Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19. Intensive Care Med 2020;epublished May 15th
• DeJong. An Ethical Framework for Allocating Scarce Inpatient Medications for COVID-19 in the US. JAMA 2020;epublished May 15th
• Angulo. Reopening Society and the Need for Real-Time Assessment of COVID-19 at the Community Level. JAMA 2020;epublished May 15th

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Thursday May 14th

Commentaries

• Hooper. COVID-19 and Racial/Ethnic Disparities. JAMA 2020;epublished May 11th
• Kirkcaldy. COVID-19 and Postinfection Immunity. Limited Evidence, Many Remaining Questions. JAMA 2020;epublished May 11th
• Levi. Coagulation abnormalities and thrombosis in patients with COVID-19. Lancet Haematol 2020;epublished May 11th
• Pollett. Social media and the new world of scientific communication during the COVID19 pandemic. Clinical Infectious Diseases 2020;epublished May 12th
• Dzau. Preventing a Parallel Pandemic — A National Strategy to Protect Clinicians’ Well-Being. N Engl J Med 2020;epublished May 13th
• Manchanda. Inequity in Crisis Standards of Care. N Engl J Med 2020;epublished May 13th
• Ison. Emergency Use Authorization of RemdesivirThe Need for a Transparent Distribution Process. JAMA 2020;epublished online May 14

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Wednesday May 13th

Editorials

• Glasziou. Waste in covid-19 research. BMJ 2020;369:m1847
• Scally. The UK’s public health response to covid-19. BMJ 2020;369:m1932
• Watson. Interpreting a covid-19 test result. BMJ 2020;369:m1808
• Alderwick. England’s health policy response to covid-19. BMJ 2020;369:m1937
• Spadaro. A Physiological Point of View on Expiratory (Re)action during Mechanical Ventilation. Am J Respir Crit Care Med 2020;201(10):1170–1172
• Williams. COVID-19 and Health Equity—A New Kind of “Herd Immunity”. JAMA 2020;epublished May 11th
• Cortegiani. Chloroquine for COVID-19: rationale, facts, hopes. Critical Care 2020;24:210
• Mojoli. Our recommendations for acute management of COVID-19. Critical Care 2020;24:207
• Ye. Avoiding hospital-related infections during the COVID-19 epidemic. Critical Care 2020;24:206
• Joebges. Ethics guidelines on COVID-19 triage—an emerging international consensus. Critical Care 2020;24:201
• Shen. Psychological stress of ICU nurses in the time of COVID-19. Critical Care 2020;24:200

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Tuesday May 12th

Guidelines & Position Statements

• Takhar. Recommendation of a practical guideline for safe tracheostomy during the COVID-19 pandemic. Eur Arch Otorhinolaryngol 2020;epublished April 21st
• Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement. Am J Respir Crit Care Med 2020;201(10):1182–1192
• Hughes. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention. Anesth Analg 2020;130(6):1572-1590
• European Section/Board of Anaesthesiology/European Society of Anaesthesiology consensus statement on competency-based education and training in anaesthesiology. Eur J Anaesthesiol 2020;37:421–434
• Harhay. Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop. Intensive Care Med 2020;46:930–942

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Monday May 11th

Narrative Reviews

Clinical

• Feldmann. Ebola. N Engl J Med 2020;382:1832-1842
• Dubin. Central venous minus arterial carbon dioxide pressure to arterial minus central venous oxygen content ratio as an indicator of tissue oxygenation: a narrative review. Rev Bras Ter Intensiva. 2020;32(1):115-122
• Huang. Clinical prediction models for acute kidney injury. Rev Bras Ter Intensiva 2020;32(1):123-132
• Jamil. Diagnosis and Management of COVID-19 Disease. Am J Respir Crit Care Med 2020;201(10):P19-P20
• Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine. Critical Care 2020;24:224
• Goh. Preparing your intensive care unit for the COVID-19 pandemic: practical considerations and strategies. Critical Care 2020;24:215
• Roumy. Pulmonary complications associated with veno-arterial extra-corporeal membrane oxygenation: a comprehensive review. Critical Care 2020;24:212
• Kowalewski. COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review. Critical Care 2020;24:205
• Li. Acute respiratory failure in COVID-19: is it “typical” ARDS? Critical Care 2020;24:198
• Schulz. Revisited: Therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics. Critical Care 2020;24:195
• Saran. Heating, ventilation and air conditioning (HVAC) in intensive care unit. Critical Care 2020;24:194
• Tran. Iatrogenic Decompensated Heart Failure. Current Heart Failure Reports 2020;17:21–27
• Morau. Anaesthesia and intensive care in obstetrics during the COVID-19 pandemic. Anaesth Crit Care Pain Med 2020;epublished May 13th

Sunday May 10th

Research

Randomised Controlled Trials

• Full Text:  Sadan. Low-chloride- versus high-chloride-containing hypertonic solution for the treatment of subarachnoid hemorrhage–related complications: The ACETatE (A low ChloriE hyperTonic solution for brain Edema) randomized trial. J Intensive Care 2020;8:32
  May 4th
• Full Text:  Cao. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19. N Engl J Med 2020;382:1787-1799
  • Editorial:  Baden. Covid-19 — The Search for Effective Therapy. N Engl J Med 2020;382:1851-1852
• Full Text:  Hung. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet 2020;epublished May 8th
• Abstract:  Yang. Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke. N Engl J Med 2020;epublished May 6th
• Abstract:  Chaumeron. Efficacy and safety of remifentanil in a rapid sequence induction in elderly patients: A three-arm parallel, double blind, randomised controlled trial. Anaesth Crit Care Pain Med 2020;39(2):215-220

Systematic Reviews & Meta Analyses

• Abstract:  Elkady. Vasopressors in Septic Shock (A Systematic Review / Meta-Analysis). QJM: An International Journal of Medicine 2020;113(Supplement 1):hcaa039.034
• Full Text:  Machado. Administration of enteral nutrition in the prone position, gastric residual volume and other clinical outcomes in critically ill patients: a systematic review. Rev Bras Ter Intensiva 2020;32(1):133-142
• Full Text:  Deschamps. Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: a systematic review and meta-analysis. Critical Care 2020;24:213
• Full Text:  Chen. Furosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis. Critical Care 2020;24:202
• Full Text:  Huang. Can computed tomography be a primary tool for COVID-19 detection? Evidence appraisal through meta-analysis. Critical Care 2020;24:193
• Abstract:  Poulton. The Association of Frailty With Adverse Outcomes After Multisystem Trauma: A Systematic Review and Meta-analysis. Anesth Analg 2020;130(6):1482-1492

Observational Studies

• Full Text:  Cavalli. Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study. Lancet Rheum 2020;epublished May 7th
  • Editorial:  Mehta. Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome. Lancet Rheum 2020;epublished May 4th
• Full Text:  Mehta. Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19). JAMA Cardiol 2020;epublished May 5th
• Editorial:  Thomas. Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19). JAMA Cardiol 2020;epublished May 5th
• Full Text:  Okada. Association between low pH and unfavorable neurological outcome among out-of-hospital cardiac arrest patients treated by extracorporeal CPR: a prospective observational cohort study in Japan. J Intensive Care 2020;8:34
• Full Text:  Helms. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med 2020;epublished May 4th
• Abstract:  Tschernatsch. Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography. Intensive Care Med 2020;epublished May 13th
• Abstract:  Nolan. Intraosseous versus intravenous administration of adrenaline in patients with out-of-hospital cardiac arrest: a secondary analysis of the PARAMEDIC2 placebo-controlled trial. Intensive Care Med 2020;2020;46:954–962
• Abstract:  Bongiovanni. Standardized EEG analysis to reduce the uncertainty of outcome prognostication after cardiac arrest. Intensive Care Med 2020;46:963–972
• Full Text:  Robba. Tracheostomy practice and timing in traumatic brain-injured patients: a CENTER-TBI study. Intensive Care Med 2020;46:983–994

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Saturday May 9th

Correspondence

• Reinhart. Sepsis hysteria: facts versus fiction. Intensive Care Med 2020;epublished May 4th
• Parri. Children with Covid-19 in Pediatric Emergency Departments in Italy. N Engl J Med 2020;epublished May 1st
• Liu. Terlipressin in septic shock: what do we know? J Thorac Dis 2020;12(4):1632-1634
• Wang. IL-6 may be a good biomarker for earlier detection of COVID-19 progression. Intensive Care Med 2020;epublished May 8th
• Chen. New device and technique to protect intubation operators against COVID-19. Intensive Care Med 2020;epublished May 8th
• Cuadrado-Payán. SARS-CoV-2 and influenza virus co-infection. Lancet 2020;395(10236):e84
• Gross. COVID-19-associated nephritis: early warning for disease severity and complications? Lancet 2020;395(10236):E87-E88
• Chu. Early Detection of Covid-19 through a Citywide Pandemic Surveillance Platform. N Engl J Med 2020;epublished May 1st
• Various. Covid-19 in South Korea — Challenges of Subclinical Manifestations. N Engl J Med 2020;382:1858-1859
• Various. Clinical Characteristics of Covid-19 in China. N Engl J Med 2020;382:1859-1862
• Various. Epidemiology of Covid-19. N Engl J Med 2020;382:1869-1870
• Haug. French Pandemic Resistance. N Engl J Med 2020;382:e51
• Various. First Case of Covid-19 in the United States. N Engl J Med 2020;382:e53
• Chung. Association between Angiotensin Blockade and Incidence of Influenza in the United Kingdom. N Engl J Med 2020;epublished May 8th
• Various. A Trial of Lopinavir–Ritonavir in Covid-19. N Engl J Med 2020;epublished May 5th
• McAnulty. Suppressing the Epidemic in New South Wales. N Engl J Med 2020;epublished May 8th
• Various. More on Barrier Enclosure during Endotracheal Intubation. N Engl J Med 2020;epublished May 5th
• Various. Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19. N Engl J Med 2020;epublished May 5th

Case Reports

• Castelein. Impella to Resist the Storm. Heart Failure 2020;13:e006698
• Kousa. Multiorgan fatal gas gangrene in the setting of clostridium septicum bacteremia: a case report. J Emerg Crit Care Med 2020;4:21
• López-Sánchez. Extracorporeal carbon dioxide removal with continuous renal replacement therapy. Case description and literature review. Rev Bras Ter Intensiva. 2020;32(1):143-148
• Duarte. Kounis syndrome. Apropos of a clinical case. Rev Bras Ter Intensiva. 2020;32(1):149-152
• Duclos. “No dose” lung ultrasound correlation with “low dose” CT scan for early diagnosis of SARS-CoV-2 pneumonia. Intensive Care Med 2020;epublished May 4th
• Riera. Full neurological recovery 6 h after cardiac arrest due to accidental hypothermia. Lancet 2020;395(10236):e89
• Munoz. Late-Onset Neonatal Sepsis in a Patient with Covid-19. N Engl J Med 2020; 382:e53
• Creel-Bulos. Acute Cor Pulmonale in Critically Ill Patients with Covid-19. N Engl J Med 2020;epublished May 6th

Podcasts

• Rubin. Audio Interview: Loosening Covid-19 Restrictions. N Engl J Med 2020;epublished Med 2020;382:e67
• Baden. Audio Interview: Studying Potential Covid-19 Therapies. N Engl J Med 2020;382:e72
• Berwick. COVID-19 and Health Care's New Normal. JAMA 2020;epublished May 6th
• Young. When Should Physicians Act on Non–Statistically Significant Results From Clinical Trials? JAMA 2020;epublished May 8th
• Cluster Randomized Trials: Evaluating Treatments Applied to Groups With William J. Meurer, MD. JAMA 2020;epublished May 7th
• Schuchat. Coronavirus Q&A: Update From the CDC. JAMA 2020;epublished May 5th
• Drs. Robert Whittington and Shahzad Shaefi discuss “Frailty in Critical Care Medicine: A Review” in Anesth Analg 2020;130(6)
• Drs. Robert Whittington and Daniel McIsaac discuss “Frailty for Perioperative Clinicians: a..." in Anesth Analg 2020;130(6)

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Friday May 8th

Commentaries

• Liu. COVID-19: The first documented coronavirus pandemic in history. Biomedical Journal 2020;epublished May 5th
• Hatipoğlu. Can multiple ARDS patients be ventilated with a single ventilator? Cleve Clin J Med 2020;87(5):259-261
• Sethuraman. Interpreting Diagnostic Tests for SARS-CoV-2. JAMA 2020;epublished May 6th
• Berwick. Choices for the “New Normal”. JAMA 2020;epublished May 4th
• Khullar. COVID-19 and the Financial Health of US Hospitals. JAMA 2020;epublished May 4th
• Livingston. Surgery in a Time of UncertaintyA Need for Universal Respiratory Precautions in the Operating Room. JAMA 2020;epublished May 7th
• Bollyky. The Equitable Distribution of COVID-19 Therapeutics and Vaccines. JAMA 2020;epublished May 7th
• Hall. Privileges and Immunity Certification During the COVID-19 Pandemic. JAMA 2020;epublished May 6th
• Persad. The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”). JAMA 2020;epublished May 6th
• Lobo. Choosing Wisely in intensive care medicine. Rev Bras Ter Intensiva 2020;32(1):11-13
• Serafim. What every intensivist needs to know about subsyndromal delirium in the intensive care unit. Rev Bras Ter Intensiva 2020;32(1):14-16
• Volpicelli. What’s new in lung ultrasound during the COVID-19 pandemic. Intensive Care Med 2020;epublished May 4th
• Schwalbe. Artificial intelligence and the future of global health. Lancet 2020;395(10236):1579-1586
• Kahn. Pandemic and Persona. N Engl J Med 2020;epublished May 6th
• Kramer. CPR in the Covid-19 Era — An Ethical Framework. N Engl J Med 2020;epublished May 6th
• Chowkwanyun. Racial Health Disparities and Covid-19 — Caution and Context. N Engl J Med 2020;epublished May 6th   
• Rosenbaum. Once Upon a Time…the Hero Sheltered in Place. N Engl J Med 2020;epublished May 6th   
• Feinmann. PPE: what now for the global supply chain? BMJ 2020;369:m1910
• Fagiuoli. Adaptations and Lessons in the Province of Bergamo. N Engl J Med 2020;epublished May 5th

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Thursday May 7th

Editorials

• Bauchner. Randomized Clinical Trials and COVID-19. Managing Expectations. JAMA 2020;epublished May 4th
• Yang. Hepatic dysfunction in critically ill patients. Acute Crit Care 2020;35(1):44-45
• Ling. COVID-19: A critical care perspective informed by lessons learnt from other viral epidemics. Anaesth Crit Care Pain Med 2020;39(2):163-166
• Rello. Coronavirus Disease 2019 (COVID-19): A critical care perspective beyond China. Anaesth Crit Care Pain Med 2020;39(2):167-169

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Wednesday May 6th

Narrative Reviews

Clinical

• Priori. COVID-19 gone bad: A new character in the spectrum of the hyperferritinemic syndrome? Autoimmunity Reviews 2020;epublished May 5th
• Rojas. Convalescent plasma in Covid-19: Possible mechanisms of action. Autoimmunity Reviews 2020;epublished May 5th
• Bergmann. COVID-19: Coronavirus replication, pathogenesis, and therapeutic strategies. Cleve Clin J Med 2020;epublished May 4th
• Jamilloux. Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions. Autoimmunity Reviews 2020;epublished May 4th
• Price. Respiratory management in severe acute respiratory syndrome coronavirus 2 infection. Eur Heart J Acute Cardiovasc Care 2020 May 7:2048872620924613
• Li. Acute respiratory failure in COVID-19: is it "typical" ARDS? Crit Care 2020;24(1):198
• Price. Respiratory management in severeacute respiratory syndromecoronavirus 2 infection. European Heart Journal: Acute Cardiovascular Care 2020;epublished May 7th
• Naksuk. Cardiac safety of off-label COVID-19 drug therapy: a review and proposed monitoring protocol. Acute Cardiovascular Care 2020;epublished May 6th
• Delang. Medical treatment options for COVID-19. Acute Cardiovascular Care 2020;epublished May 4th

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Tuesday May 5th

Guidelines & Position Statements

• Advanced Pulmonary and Cardiac Support of COVID-19 Patients. Emerging Recommendations From ASAIO—a Living Working Document. Heart Failure. 2020;13:e007175
• Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection. Revista Española de Anestesiología y Reanimación 2020;epublished May 7th
• Abdul-Aziz. Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper. Intensive Care Med 2020;epublished May 7th
• Recommendations from the Sociedade Portuguesa de Cuidados Intensivos and Infection & Sepsis Group for intensive care approach to COVID-19. Rev Bras Ter Intensiva. 2020;32(1):2-10
• Legrand. Management of severe thermal burns in the acute phase in adults and children. Anaesth Crit Care Pain Med 2020;39(2):253-267
• Bouzat. Early management of severe abdominal trauma. Anaesth Crit Care Pain Med 2020;39(2):269-277
• French recommendations for the management of patients with spinal cord injury or at risk of spinal cord injury. Anaesth Crit Care Pain Med 2020;39(2):279-289
• Gruel. Diagnosis and management of heparin-induced thrombocytopenia. Anaesth Crit Care Pain Med 2020;39(2):291-310
• L'Her. Simulation-based teaching in critical care, anaesthesia and emergency medicine. Anaesth Crit Care Pain Med 2020;39(2):311-326

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Monday May 4th

Narrative Reviews

Clinical

• Editorial:  Arina. From "bad infection" to organ failure. Med Klin Intensivm