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CCR Meeting Talks

After 14 meetings, we have a huge collection of superb presentations. We'll showcase them here, one at a time.

CCR19

APROCCHSS Trial Review

Prof Djillali Annane (Paris) discusses the APROCCHSS trial, investigating fludrocortisone and hydrocortisone in septic shock.

added August 17th

CCR Down Under 2025 Trials to Date

Join us in Melbourne, December 9th & 10th, to discuss the best critical care trials in the world

Journal Watch Latest

TIGRIS Trial Result Press Release - Polymyxin B Hemoadsorption Therapy for Endotoxic Septic Shock

  • Results exceed prespecified primary endpoint of 95% posterior probability of benefit for PMX on 28-day mortality
  • Pooled absolute risk reduction of 8.3%; Relative risk reduction of 18%
  • Key secondary endpoint: 90-day Mortality 17.4% lower with PMX and >99% posterior probability of benefit
  • 38.7% Mortality at 28 days with PMX confirms results of prior trial subset

added August 13th

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Sample Issue

Narrative Review

Yamamoto. Mechanism of sepsis. J Mol Pathol 2025;6:18

added August 14th

image: Shutterstock / Kateryna Kon

CCR Content

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Newsletter 714

Critical Care Reviews Newsletter 714, bringing you the best critical care research and open access articles for the week August 11th to 17th.

Subscriptions are available to individuals and departments.

added August 18th

Adrenal tumour on imaging

Paper of the Day

Monday, August 18th

Yan. The effect of opioids on gastrointestinal function in the ICU. Crit Care 2021;25(1):370

Join us to read one paper per day and cover the spectrum of critical care across 2025. Previous papers of the day are available here.

Have it emailed to you!

image: Shutterstock / Svetlana Beleacov
MRI showing traumatic spinal cord injury

Highlighted Narrative Reviews

With thousands of open access narrative reviews listed across the website, CCR provides a comprehensive educational resource. We'll highlight one topic here every few days. Today, we look at Traumatic Spinal Cord Injury

added August 12th

Propofol syringe in syringe driver

Foundational Trials

Guérin C, Reignier J, Richard JC et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med  2013;368(23):2159‑2168

It's the latest in our Foundational Trials collection, looking at the trials which underpin contemporary critical care practice

added August 11th

image: Shutterstock / Shellygraphy
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Highlighted Guidelines

Need a guideline, or just want to refresh your knowledge on the evidence-based management of a particular condition? We provide more up-to-date guidelines than any other critical care resource. Have a look at our ARDS Guideline section

added August 12th

image: Shutterstock / tungtaechit

CCR Down Under 2025

Registration has opened for CCR Down Under in Melbourne, on December 9th and 10th, again at the Edge in Federation Square.

We aim to bring another set of fantastic international critical care trials to Australia. If you are interested in the science underlying clinical practice, this is the meeting for you.

We're delighted to be partnering once again with the Alfred Intensive Care Academic Centre, and this year, with Monash University.

If you missed the presentations last December, the presentations of the so far published trials are available here.

Register