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CCR Down Under 2025


The Third Trial to be Announced is:

Standard low flow oxygen vs high flow nasal oxygen vs CPAP in acute hypoxaemic respiratory failure

Paul Young asks a question at CCR Down Under

Previously Announced


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CCR Down Under 2025


Registration has opened for CCR Down Under in Melbourne, on December 9th and 10th, again at the Edge in Federation Square.

We aim to bring another set of fantastic international critical care trials to Australia. If you are interested in the science underlying clinical practice, this is the meeting for you.

We're delighted to be partnering once again with the Alfred Intensive Care Academic Centre, and this year, with Monash University.

If you missed the presentations last December, the presentations of the so far published trials are available here.


CCR Content


Echocardiogram showing the left ventricle

Paper of the Day

Friday, July 25th

Delle Femine. Echocardiography in the Ventilated Patient: What the Clinician Has to Know. J Clin Med 2025;14:77

Join us to read one paper per day and cover the spectrum of critical care across 2025. Previous papers of the day are available here.

Have it emailed to you!

image: Shutterstock / BelezaPoy
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Newsletter 710

Critical Care Reviews Newsletter 710, bringing you the best critical care research and open access articles for the week July 14th to 20th.

Subscriptions are available to individuals and departments.

added July 20th

Propofol syringe in syringe driver

Foundational Trials

Kress. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342(20):1471-7

We start a new section looking at the foundation trials in critical care and start with probably the most important trial yet in the field.

added July 15th

image: Shutterstock / Sora
Urine container

Highlighted Narrative Reviews

With thousands of open access narrative reviews listed across the website, CCR provides a comprehensive educational resource. We'll highlight one topic here every few days. Today, we look at Acute Kidney Injury

added July 15th

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Highlighted Guidelines

Need a guideline, or just want to refresh your knowledge on the evidence-based management of a particular condition? We provide more up-to-date guidelines than any other critical care resource. have a look at our Burns guideline section

added July 13th

image: Shutterstock / Medical-R

CCR Meeting Talks


After 14 meetings, we have a huge collection of superb presentations. We'll showcase them here, one at a time.

CCR24


The PRE-OXI Trial Results

Jonathan Casey and Kevin Gibbs present the results of the PRE-OXI trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast. PRE-OXI investigated non-invasive ventilation for preoxygenation in emergency intubation in the critically ill.

Yonathan Freund delivers an independent editorial. Catriona Kelly chairs a panel discussion with Anthony Gordon, Sheila Myatra, Victoria Cornelius and Jan Gunst.

PRE-OXI was simultaneously published in the New England Journal of Medicine.


added July 21st