Georgopoulos. Mechanical Ventilation in Patients with Acute Brain Injuries: A Pathophysiology-based Approach. Am J Respir Crit Care Med 2025;211(6):932-945

The 766th Critical Care Reviews Newsletter is now out, covering the week of August 10th to 16th. Individual and unit subscriptions are available.

ICECAP Trial

Meurer. Duration of therapeutic hypothermia after out-of-hospital cardiac arrest: the ICECAP randomized clinical trial. JAMA 2026;epublished August 5th

Interested in traumatic brain injury? We have links to 161 open access narrative review articles on this topic.

Meurer. Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest. The ICECAP Randomized Clinical Trial. JAMA 2026;epublished August 5th

We have an enormous section of open access narrative review articles from across the medical literature. Check out our page on haemostatic resuscitation, updated August 4th

MERCURI-2 Trial

Oosterom-Eijmael. MERCURI-2 Study Group. Dapagliflozin and acute kidney injury following cardiac surgery: a randomized clinical trial. JAMA 2026;epublished July 30th

PROPOSITIS Trial

Baudin. Prone Positioning in Infants With Acute BronchiolitisThe PROPOSITIS Randomized Clinical Trial. JAMA 2026;336(4):315-322

PAEAN Trial

Liley. Erythropoietin for neonatal hypoxic-ischemic encephalopathy: a randomized clinical trial. JAMA Pediatr. 2026;epublished July 27th.

Today, we look at one of the seminal trials in anaemia management in the critically ill. Read our summary and critique of the TRICC trial.

The next Critical Care Reviews Meeting in Titanic Belfast is on June 9th to 11th, 2027. Registration will open later in the year. If you want to get in touch about it, please This email address is being protected from spambots. You need JavaScript enabled to view it.

Ary Serpa Neto presents the SODa-BIC trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast.

Need a guideline? We have a huge selection of open access critical care guidelines. Have a look at our cardiac arrest page.