Narrative Reviews
Acute Pancreatitis
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General
General
- Hu. Acute pancreatitis: mechanisms and therapeutic approaches. Signal Transduct Target Ther. 2026;11(1):15.
- Carrara. Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management. J Clin Med. 2026;15(8):2819.
- Beij. Acute Pancreatitis: An Update of Evidence‐Based Management and Recent Trends in Treatment Strategies. United European Gastroenterol J 2025;13(1):97–106
- Hawatian. Contemporary Approach to Acute Pancreatitis in Emergency Medicine. JAECEP Open 2025;6(2):100063
- Ben-Ami Shor. The Multidisciplinary Approach to Acute Necrotizing Pancreatitis. J Clin Med. 2025;14(9):2904.
- Amodio. Management of acute pancreatitis in the “no man’s land”. Intern Emerg Med. 2025;20(5):1319-1327.
- Trikudanathan. Diagnosis and Management of Acute Pancreatitis. Gastroenterology. 2024;167(4):673-688.
- Hamesch. Practical management of severe acute pancreatitis. Eur J Intern Med 2024;epublished November 29th
- Song. Recent Treatment Strategies for Acute Pancreatitis. J Clin Med. 2024;13(4):978.
- Palumbo. Contemporary management of acute pancreatitis: What you need to know. J Trauma Acute Care Surg 2023;96(1):156-165
Necrotizing Pancreatitis
- Pauw. Antimicrobial therapy for infected necrotizing pancreatitis: microbiology, antimicrobial resistance and pharmacokinetics. J Antimicrob Chemother. 2026;81(4):dkag092.
- Devasahayam. Sit on your Hands, Dear Surgeon – Delayed Intervention and Medical Optimization in Necrotizing Pancreatitis Improves Outcomes. Curr Surg Rep. 2026;14:13.
- Jakanov. Necrotic pancreatitis: modern approaches to the prevention of infected necrosis. Front Med 2026;12:1695035.
- Mirza-Aghazadeh-Attari. Percutaneous Interventions and Necrosectomy in the Management of Peripancreatic Collections. Semin Intervent Radiol. 2025;42(1):82-92.
Artificial Intelligence
- Dumitrascu. Management and Prediction of Acute Pancreatitis Severity Using AI: A Surgical Perspective. Diagnostics 2026;16(9):1350.
- Zhang. Artificial intelligence in pancreatitis: A narrative review on advancing precision diagnosis, prognosis, and therapeutic strategies. World J Gastroenterol. 2025;31(39):110971.
- López Gordo. AI and Machine Learning for Precision Medicine in Acute Pancreatitis: A Narrative Review. Medicina 2025;61(4):629.
Background
Pathophysiology
- Xia. Reactive oxygen species and oxidative stress in acute pancreatitis: Pathogenesis and new therapeutic interventions. World J Gastroenterol. 2024;30(45):4771-4780.
- Gukovskaya. Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon? World J Gastroenterol. 2024;30(41):4417-4438.
- Rafaqat. Interleukins: pathophysiological role in acute pancreatitis. Arch Med Sci. 2024;20(1):138-156.
- Zaman. Acute pancreatitis: pathogenesis and emerging therapies. J Pancreatol. 2024;7(1):10-20.
- Walkowska. The Pancreas and Known Factors of Acute Pancreatitis. J Clin Med 2022;11(19):5565
Gut Microbiome
- Nista. Exploring the Role of Gut Microbiota and Probiotics in Acute Pancreatitis: A Comprehensive Review. Int J Mol Sci. 2025;26(7):3433.
- Liu. Updated review of research on the role of the gut microbiota and microbiota-derived metabolites in acute pancreatitis progression and inflammation-targeted therapy. Int J Biol Sci. 2025;21(3):1242-1258.
- Yazici. Alterations in microbiome associated with acute pancreatitis. Curr Opin Gastroenterol. 2024;40(5):413-421.
- Lupu. Exploring the Microbial Landscape: Gut Dysbiosis and Therapeutic Strategies in Pancreatitis—A Narrative Review. Biomedicines. 2024;12(3):645.
- Zhou. The Role of the Gut Microbiome in the Development of Acute Pancreatitis. Int J Mol Sci. 2024;25(2):1159.
- Zhang. The Interaction of Microbiome and Pancreas in Acute Pancreatitis. Biomolecules. 2024;14(1):59.
- Wu. Gut microbiota interacts with inflammatory responses in acute pancreatitis. Ther Adv Gastroenterol. 2023;16:17562848231202133.
Conditions
Gallstone Pancreatitis
Hypertriglyceridaemia-Associated
- Li. Hypertriglyceridaemia-Associated Acute Pancreatitis: Pathophysiological Insights and Advances in Clinical Management. Biomedicines. 2026;14(7):1574.
- Subramanian. Prevention and treatment of hypertriglyceridemia-mediated acute pancreatitis: A narrative review. Eur J Intern Med. 2026;145:106648.
- Fogacci. Hypertriglyceridaemia-Associated Acute Pancreatitis: Risk Stratification, Drivers, and Prevention of Recurrence. Diseases. 2026;14(2):47.
- Guo. The role of intestinal microbiota and its metabolite short-chain fatty acids in hypertriglyceridemia-associated acute pancreatitis. Front Microbiol. 2025;16:1667075.
- Gao. Hypertriglyceridemia and acute pancreatitis: clinical and basic research—a narrative review. J Pancreatol. 2024;7(1):53-60.
Complications
Pancreas
Feeding Intolerance
Metabolic Disorders
Systemic
Acute Lung Injury
- Ye. Exploring the mechanism and potential treatment of severe acute pancreatitis-associated lung injury based on the gut-lung axis. World J Gastrointest Surg. 2026;18(4):116918.
- Jun. Oxidative stress in acute pancreatitis induced acute lung injury: mechanisms and therapeutic advances. PeerJ. 2026;14:e20905.
- Liu. From pancreas to lungs: The role of immune cells in severe acute pancreatitis and acute lung injury. Immun Inflamm Dis. 2024;12(7):e1351.
Coagulopathy
Multi-Organ Dysfunction Syndrome
Monitoring & Investigations
Biomarkers
Therapies
Fluids
Nutrition
- Shamoon. Translational Pharmaco-Nutritional Approaches in the Management of Clinical Acute Pancreatitis—A Narrative Review. Pharmaceuticals 2025;18(11):1621.
- Sun. Nutrition therapy in critically ill patients with severe acute pancreatitis. Nutr Clin Pract. 2024;39(2):271-280.
- Chen. Timing and Route of Nutritional Therapy for Severe Acute Pancreatitis: From Bench to Bedside. J Transl Crit Care Med 2022;4:12
Analgesia
Endoscopic Management
- Mukai. Endoscopic Step-up Approach for Walled-off Necrosis After Acute Pancreatitis. DEN Open. 2026;6(1):e70188.
- Zeng. Endoscopic Management of Infected Necrotizing Pancreatitis: Advancing Through Standardization. World J Gastroenterol. 2025;31(20):107451.
- Testoni. Endoscopic Management of Recurrent Acute Pancreatitis. J Clin Med 2025;14:2150
Percutaneous Drainage
- Liu. Application and Value of Percutaneous Catheter Drainage in Contemporary Surgical Treatment of Pancreatic Necrosis. Dig Dis Sci. 2025;70:2977-2989.
- Mirza-Aghazadeh-Attari. Percutaneous Interventions and Necrosectomy in the Management of Peripancreatic Collections. Semin Intervent Radiol. 2025;42(1):82-92.
Intervention Timing
Last updated August 6th, 2026