Lars Andersen presents the VAM-IHCA trial at CCR22
Welcome to the 562nd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials evaluating fluid resuscitation in acute pancreatitis & remote ischemic conditioning in septic shock; systematic reviews and meta analyses on vasopressin during cardiopulmonary resuscitation & vasoactive treatments for hepatorenal syndrome; and observational studies on the differential response to convalescent plasma in critically ill patients with COVID-19 & respiratory support in patients with severe COVID-19.
There are also guidelines on palliative care early in the care continuum among patients with serious respiratory illness & severe acute pancreatitis; narrative reviews on indications and timing of initiation of KRT & critical illness and bone metabolism; commentaries on source control in the management of sepsis and septic shock & the glycocalyx as a permeability barrier. There is also a fantastic series from Anaesthesia on "Emergencies in Anaesthesia".
If you only have time to read one review article this week, try this one on the end of “One Size Fits All” sepsis therapies: toward an individualized approach.
The latest video to be released from CCR22 is the VAM-IHCA trial presentation by Lars Andersen, from Aarhus, Denmark. This ties in beautifully with this week's visual abstract from Jakub Fronczek, which is also on the VAM-IHCA trial. Follow us on Instagram to stay current with these superb infographics.
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Research
Randomised Controlled Trials
- de-Madaria. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis. N Engl J Med 2022;387:989-1000
- Cour. Remote ischemic conditioning in septic shock: the RECO-Sepsis randomized clinical trial. Intensive Care Med 2022;epublished September 14th
- Bowdish. A Randomized Trial of Mesenchymal Stromal Cells for Moderate to Severe ARDS From COVID-19. Am J Respir Crit Care Med 2022;epublished September 13th
- Pavitt. Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study. Thorax 2022;77:968-975
- Poole. Molecular point-of-care testing for lower respiratory tract pathogens improves safe antibiotic de-escalation in patients with pneumonia in the ICU: results of a randomised controlled trial. J Infect 2022;epublished September 9th
Systematic Review & Meta Analyses
- Rolle. Cardiac arrest and complications during non-invasive ventilation: a systematic review and meta-analysis with meta-regression. Intensive Care Med 2022;epublished September 16th
- Pitre. The Comparative Effectiveness of Vasoactive Treatments for Hepatorenal Syndrome: A Systematic Review and Network Meta-Analysis. Crit Care Med 2022;50(10):1419-1429
- Maertens. Effectiveness of Continuous Cuff Pressure Control in Preventing Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Crit Care Med 2022;50(10):1430-1439
- Lockstone. Prophylactic Postoperative Noninvasive Ventilation in Adults Undergoing Upper Abdominal Surgery: A Systematic Review and Meta-Analysis. Crit Care Med 2022;50(10):1522-1532
- Elbadawi. Meta-Analysis of Efficacy of Vasopressin During Cardiopulmonary Resuscitation. Am J Cardiol 2022;181:122-129
- Zhu. Utility of viscoelastic hemostatic assay to guide hemostatic resuscitation in trauma patients: a systematic review. World J Emerg Surg 2022;17:48
- Yang. Target Temperature Management Versus Normal Temperature Management for Cardiac Arrest After Traumatic Brain Injury Patient: A Meta-Analysis and Systemic Review. Ther Hypothermia Temp Manag 2022;12(3):139-145
- Azad. Reexamining the Role of Postoperative ICU Admission for Patients Undergoing Elective Craniotomy: A Systematic Review. Crit Care Med 2022;50(9):1380-1393
Observational Studies
- Fish. Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial. Intensive Care Med 2022;epublished September 14th
- López-Martínez. Transcriptomic clustering of critically ill COVID-19 patients. Eur Respir J 2022;epublished September 14th
- Pari. Collaboration for Research Implementation, Training in Critical Care, Asia Africa ‘CCAA’. Development of a quality indicator set to measure and improve quality of ICU care in low- and middle-income countries. Intensive Care Med 2022;epublished September 16th
- Fink. Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest. JAMA Netw Open 2022;5(9):e2230518
- Reyes. Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study. Crit Care 2022;26:276
- Somhorst. PEEP-FiO 2 table versus EIT to titrate PEEP in mechanically ventilated patients with COVID-19-related ARDS. Crit Care 2022;26(1):272
Guidelines
- Palliative Care Early in the Care Continuum among Patients with Serious Respiratory Illness: An Official ATS/AAHPM/HPNA/SWHPN Policy Statement. Am J Respir Crit Care Med 2022;206(6):e44-e69
- Guidelines for the management of patients with severe acute pancreatitis, 2021. Anaesth Crit Care Pain Med 2022;41(3):101060
- Shang. Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019. Chin Med J 2022;epublished September 12th
- Peng. Society of Cardiovascular Anesthesiologists Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery. Anesth Analg 2022;135(4):744-756
- Management of Patients at Risk for and With Left Ventricular Thrombus: A Scientific Statement From the American Heart Association. Circulation 2022;epublished September 15th
- Joint British Society consensus recommendations for magnetic resonance imaging for patients with cardiac implantable electronic devices. Heart 2022;epublished September 14th
Reviews
Clinical
COVID-19
Neurological
- Mina. Noninvasive Ventilation in Treatment of Respiratory Failure-Related COVID-19 Infection: Review of the Literature. Can Respir J 2022;2022:9914081
- Czosnyka. Pro-Con Debate: The Clinical (Ir)relevance of the Lower Limit of Cerebral Autoregulation for Anesthesiologists. Anesth Analg 2022;135(4):734-743
- Yum. Transient splenial lesions of the corpus callosum and infectious diseases. Acute Crit Care 2022;37(3):269-275
Circulatory
- Schäfer. Novel therapeutic strategies to reduce reperfusion injury after acute myocardial infarction. Curr Probl Cardiol 2022;epublished September 12th 12:101398
- Del Buono. Ischemic Cardiomyopathy and Heart Failure After Acute Myocardial Infarction. Curr Cardiol Rep 2022;epublished August 16th
Nutrition
Hepatobiliary
- Ballester. Alcohol and Acute-on-Chronic Liver Failure. J Clin Exp Hepatol 2022;12(5):1360–1370
- Nath. Extrahepatic Manifestations in Alcoholic Liver Disease. J Clin Exp Hepatol 2022;12(5):1371-1383
Renal
- Ostermann. Indications for and Timing of Initiation of KRT. Clin J Am Soc Nephrol 2022;epublished September 13th
- Regner. Management of AKI in Patients with Cirrhosis. Curr Treat Options Gastro 2022;epublished September 15th
- Zou. Advances in the study of subclinical AKI biomarkers. Front Physiol 2022;13:960059
Endocrine
Sepsis
Trauma
Miscellaneous
Emergencies in Anaesthesia series from Anaesthesia
- Spoelder. Transport of the patient with trauma: a narrative review. Anaesthesia 2022;epublished September 12th
- Shah. Major haemorrhage: past, present and future. Anaesthesia 2022;epublished September 12th
- McCahill. State-of-the-art management of the acutely unwell child. Anaesthesia 2022;epublished September 12th
- Prior. Emergencies in obstetric anaesthesia: a narrative review. Anaesthesia 2022;epublished September 12th
- Gottesman. Frailty and emergency surgery: identification and evidence-based care for vulnerable older adults. Anaesthesia 2022;epublished September 12th
- Wiles. Airway management in patients with suspected or confirmed traumatic spinal cord injury: a narrative review of current evidence. Anaesthesia 2022;77(10):1120-1128
- Edelman. Prevalence and commonality of non-technical skills and human factors in airway management guidelines: a narrative review of the last 5 years. Anaesthesia 2022;epublished September 12th
Pre-Clinical
Commentaries
- De Waele. Source control in the management of sepsis and septic shock. Intensive Care Med 2022;epublished September 14th
- Russell. Use of Mendelian randomization to better understand and treat sepsis. Intensive Care Med 2022;epublished September 14th
- Hopewell. An update to SPIRIT and CONSORT reporting guidelines to enhance transparency in randomized trials. Nat Med 2022;epublished September 15th
- Dull. The glycocalyx as a permeability barrier: basic science and clinical evidence. Crit Care 2022;26:273
- Berger. Clinical nutrition issues in 2022: What is missing to trust supplemental parenteral nutrition (SPN) in ICU patients?. Crit Care 2022;26:271
Correspondence
- Lopez Soto. Introducing an external team for ICU family communication during the pandemic: not without risks. Intensive Care Med 2022;epublished September 13th
- Dhooria. The answer may lie in avoiding the underwater seal rather than the chest drainage tube. Am J Respir Crit Care Med 2022;epublished September 6th
Case Reports
- Álvarez Fernández. COVID-19 associated pulmonary aspergillosis. Med Intensiva 2022;epublished July 27th
- Gómez Carranza. Diagnosis of pneumonia in Intensive Care using color Doppler. Med Intensiva 2022;epublished September 8th
- Tan. Strongyloides stercoralis hyperinfection presenting with shock and intermittent eosinophilia: A case report. Medicine 2022;101(35):e30490
- Postoperative Central Cord Syndrome: Physiologic Decapitation in the PACU. J Neuroanaesth Crit Care 2022;09(02):125-127
- Muthukalai. Hypertensive Therapy Leading to Atypical Posterior Reversible Encephalopathy Syndrome. J Neuroanaesth Crit Care 2022; 09(02): 128-129
I hope you find this newsletter useful.
Until next week
Rob