Critical Care Reviews Newsletter

Welcome to the 530th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on the effect of moderate hypothermia in patients with cardiogenic shock receiving VA-ECMO & drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction; systematic reviews and meta analyses on vasopressin, steroid, and epinephrine in cardiac arrest & prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure; and observational studies on the effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding & the effects of targeted temperature management at 33°C vs. 36°C on comatose patients after cardiac arrest stratified by the severity of encephalopathy.

There are also guidelines on temperature control after cardiac arrest in adults & pain, agitation, neuromuscular blockade, and delirium in critically ill pediatric patients; as well as narrative reviews on nitric oxide & the mechanisms of acute kidney injury secondary to acute liver injury.

If you only have time to read one review article this week, try this one on analgesia in the neurosurgical intensive care unit.

Critical Care Reviews Meeting 2022

Registration for CCR22, on June 15th to 17th at Titanic Belfast, is open.