Journal Watch 2025

Friday 18th

Guidelines & position Statements

• Neurosurgical management of the acute phase of adult and pediatric traumatic brain injury: 2025 guidelines of the French Society of Neurosurgery. Neurochirurgie 2025 Jul;71(4):101686

Narrative Reviews

Clinical

• Martin-Loeches. Severe community-acquired pneumonia (sCAP): advances in management and future directions. Thorax 2025;80:565-575

Thursday 17th

Guidelines & Position Statements

• Jourdain. Renal replacement therapy in an intensive care unit: guidelines from the SRLF-GFRUP consensus conference. Ann. Intensive Care 2025;15:100

Research

Randomised Controlled Trials

• Miatello. Inhaled isoflurane for sedation of mechanically ventilated children in intensive care (IsoCOMFORT): a multicentre, randomised, active-control, assessor-masked, non-inferiority phase 3 trial. Lancet Respir Med 2025;epublished July 15th

Systematic Reviews & Meta Analyses

• Tanvir. Effect of blood pressure threshold on adverse outcomes in patients with acute spinal cord injury: a systematic review and meta-analysis. Crit Care 2025;29:308 

Observational Studies

• Sarma. Evaluating the generalisability of formulas used to set tidal volumes in mechanically ventilated patients: an observational, multicohort, retrospective study. Lancet Respir Med 2025;epublished July 15th

Editorials

• Thille. How should spontaneous breathing trials be performed in the light of recent literature?. Ann. Intensive Care 2025;15:102 

Wednesday 16th

Narrative Reviews

Clinical

• Sekhon. Clinical heterogeneity and phenotyping of post cardiac arrest brain injury: one size may not fit all. Intensive Care Med 2025;epublished July 16th

Editorials

• Arabi. Venous thromboprophylaxis in the ICU: navigating evidence, risk, and practice gaps. Intensive Care Med 2025;epublished July 16th

Guidelines & Position Statements

• Expert consensus‑based clinical practice guidelines for nutritional support in the intensive care unit: the French Intensive Care Society (SRLF) and the French-Speaking Group of Pediatric Emergency Physicians and Intensivists (GFRUP). Ann Intensive Care 2025;15:99 

Tuesday 15th

Research

Randomised Controlled Trials

• Voiriot. Combined use of a multiplex PCR and serum procalcitonin to reduce antibiotic exposure in critically ill patients with community-acquired pneumonia: the MULTI-CAP randomized controlled trial. Intensive Care Med 2025;epublished July 15th

Narrative Reviews

Clinical

• Zarbock. Preventing acute kidney injury and its longer-term impact in the critically ill. Intensive Care Med 2025;epublished July 15th

Monday 14th

Research

Randomised Controlled Trial

• Ke. Early versus delayed catheter drainage for patients with necrotizing pancreatitis and early persistent organ failure (TIMING): a multicenter randomized controlled trial. Intensive Care Med 2025;epublished July 14th

Systematic Reviews & Meta Analyses

• Abu‐Sultaneh. Intravenous Bronchodilators in Pediatric Critical Asthma: A Systematic Review and Network Meta‐Analysis. Pediatric Pulmonology 2025;60:e71192

Observational Studies

• Tangchitthavorngul. Epidemiology and long-term outcomes of critically ill patients with severe AKI in India and Southeast Asia. Intensive Care Med 2025;epublished July 14th
• Ostadal. Cardiac index, SvO2 or pCO2 gap may determine benefit from ECMO in cardiogenic shock: post-hoc analysis of the multicenter, randomized ECMO-CS trial. Crit Care 2025;29:303
• Gross. Mortality and antibiotic timing in deep learning-derived surviving sepsis campaign risk groups: a multicenter study. Crit Care 2025;29:302

Narrative Reviews

Clinical

• Li. Crosstalk between lung and extrapulmonary organs in sepsis-related acute lung injury/acute respiratory distress syndrome. Ann. Intensive Care 2025;15:97

Commentaries

• Soussi. Cardiogenic shock syndrome unraveled: understanding the different layers of heterogeneity. Intensive Care Med 2025;epublished July 14th

Sunday 13th

Research

Randomised Controlled Trials

• Lemiale. Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial. Lancet Respir Med 2025;epublished July 10th
• Kamenshchikov. Perioperative Nitric Oxide Conditioning Reduces Acute Kidney Injury in Cardiac Surgery Patients with Chronic Kidney Disease (the DEFENDER Trial): A Randomized Controlled Trial. Anesthesiology 2025;143(2):287-299
• Téoule. Reduction of Central Venous Pressure in Elective Robotic and Laparoscopic Liver Resection: The PRESSURE Trial-A Randomized Clinical Study. Ann Surg 2025;282(2):210-218
• Glass. Effect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial. Thorax 2025;epublished July 8th
• Zhou. Preemptive left stellate ganglion block reduces the incidence and severity of cardiac surgery-associated acute kidney injury: a randomized clinical trial. Int J Surg 2025;epublished July 11th
• Sivakumar. Dexmedetomidine vs. midazolam-ketamine for sedation during awake fiberoptic nasal intubation in patients with difficult airway - A randomized, double-blinded, comparative trial. J Anaesthesiol Clin Pharmacol 2025;41(3):496-502
• Singh. TIPS Is Superior to SEMS in the Management of Refractory VARICEAL Bleed in Advanced Cirrhosis Patients (TIPSEMS-VB Trial). Liver Int 2025;45(8):e70178
• Dhakal. Palpation versus Ultrasound-Guided Dynamic Needle Tip Positioning Technique for Radial Artery Cannulation. Ann Card Anaesth 2025;28(3):248-254
• George. The Effect of Continuous Magnesium Infusion to Prevent Postoperative Atrial Fibrillation in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting. Ann Card Anaesth 2025;28(3):273-279
• Nguyen. Endotoxin removal by the OXIRIS filter for cardiogenic shock requiring veno-arterial extra-corporeal life support: the ECMORIX randomized controlled trial. Ann Intensive Care 2025;15:92
• Naslowski. Effects of probiotic supplementation on infectious and gastrointestinal complications of critically ill patients: Randomized, blinded, placebo-controlled clinical trial. Clin Nutr ESPEN 2025;68:228-237

Systematic Reviews & Meta Analyses

• Lamarche-Fontaneto. Cardiac output monitors in septic shock: do they deliver what matters? A systematic review and meta-analysis. Crit Care 2025;29:299
• Ward. The Effect of Early Fluid Resuscitation on Mortality in Sepsis: A Systematic Review and Meta-Analysis. Crit Care Med 2025;epublished July 10th
• Mateos-Haro. Recommendations for the use of biomarkers for the management of adults with sepsis: a scoping review and critical appraisal. BMJ Open 2025;15:e090922
• Cai. Neurally adjusted ventilatory assist in pediatric intensive care units: a systematic review and meta-analysis. Front Pediatr 2025;13:1597337

Observational Studies

• Zampieri. Effects of dapagliflozin on urinary output, fluid balance, and biochemistry in critically ill patients: a post-hoc secondary analysis of the DEFENDER trial. Crit Care 2025;29:297
• Shibahashi. Association of early in-hospital endotracheal intubation with clinical outcomes in patients with traumatic coma: a multicenter observational study. Crit Care 2025;29:292
• Daza. Low tidal volume ventilation and mortality in patients with acute brain injury: a secondary analysis of an international observational study. Chest 2025;epublished July 8th
• Dessajan. Assessing FilmArray Pneumonia+ panel dynamics during antibiotic treatment to predict clinical success in ICU patients with ventilated hospital-acquired pneumonia and ventilator-associated pneumonia: a multicenter prospective study. Crit Care 2025;29(1):301
• Weiss Goitiandia. Systemic Strategies to Prevent Nonbeneficial Treatments Near the End of Life. JAMA Netw Open 2025;8(7):e2519771
• Kruser. How Health Care Systems Shape End-of-Life Care—A Step Toward Transparency. JAMA Netw Open 2025;8(7):e2519777
• Smits. P0.1 is an Unreliable Measure of Effort in Support Mechanical Ventilation in Comparison With Esophageal-Derived Measures of Effort: A Comparison Study. Crit Care Med 2025;epublished June 12th
• Nay. Intra-hospital transport of adult critically ill patients treated with high flow nasal cannula oxygen: a prospective observational multicenter study. Ann Intensive Care 2025;15(1):93

Protocols

• Chen. A multicentre, randomised controlled clinical trial evaluating the effect of the adsorptive filter oXiris on haemodynamics in abdominal septic shock patients requiring continuous renal replacement therapy (Oxiris for Abdominal SEptic Shock study). BMJ Open 2025;15(7):e094792

Guidelines & Position Statements

• European Association for the Study of the Liver. EASL Clinical Practice Guidelines on TIPS. J Hepatol 2025;83(1):177-210
• Yan. 2024 Guidelines on Patient Blood Management for Adult Cardiac Surgery Under Cardiopulmonary Bypass in China. Rev Cardiovasc Med 2025;26(6):31384
• Baddley. 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People. Clin Infect Dis 2025;ciaf257

Narrative Reviews

Clinical

• Gill. Aortic Regurgitation: An Updated Review of Etiologies, Diagnostic Strategies, and Clinical Management. Rev Cardiovasc Med 2025;26(6):37259
• Jin. Classification, Diagnosis, and Prognosis of Cardiomyopathy: A Comprehensive Narrative Review. Rev Cardiovasc Med 2025;26(6):36280
• Ozyuncu. Antiplatelet Therapy in Heart Disease. Rev Cardiovasc Med 2025;26(6):36522
• Aklilu. Immunothrombosis in Sepsis: Cellular Crosstalk, Molecular Triggers, and Therapeutic Opportunities-A Review. Int J Mol Sci 2025;26(13):6114
• Matsuo. The Latest Approaches to Fracture-Related Infection. Curr Infect Dis Rep 2025;27:15
• Moore. The unwell patient with advanced chronic liver disease: when to use each score?. BMC Med 2025;23:413
• Dryden. Analyzing outcomes for peripheral versus central administration of vasopressors: A narrative review. Saudi J Anesth 2025;19(3):375-383
• Pourová. The machinery of healthy vasoconstriction: an overview. Pflugers Arch 2025;epublished July 11th
• Morrison-Nozik. Volatile anesthetics in the intensive care unit. Anaesthesiol Intensive Ther 2025;57:e165–e169

Editorials

• Skrifvars. A Personal Reflection on the Late Rinaldo Bellomo, One of the Most Prolific Researchers in Intensive Care Medicine. Acta Anaesthesiol Scand 2025;69(7):e70097

Correspondence

• Rajsic. Beyond survival: the societal value of extracorporeal cardiopulmonary resuscitation. Crit Care 2025;29:296
• Likhvantsev. Comment on the CIBCD model for chronic critical illness. Crit Care 2025;29:291
• Wang. Hemodynamic augmentation through abdominal counterpulsation in pediatric resuscitation. Resuscitation 2025;epublished July 7th

Case Reports

• Migiel. CPR-induced consciousness in hypothermic cardiac arrest: Where is the limit of tolerance of the human brain? A case report. Scand J Trauma Resusc Emerg Med 2025;33:111

Saturday 12th

Narrative Reviews

Clinical

• Tinsley. Non-insulin diabetes medicines: a narrative review for anaesthetists and intensivists. Br J Anaesth 2025;epublished July 11th
• Gianoli. Harnessing adiponectin for sepsis: current knowledge, clinical insights and future therapies. Crit Care 2025;29:300

Friday 11th

Narrative Reviews

Clinical

• Liaqat. Difficult Airway Management in the Intensive Care Unit: A Narrative Review of Algorithms and Strategies. J Clin Med 2025;14(14):4930
• Bachmann. Gastrointestinal function and nutritional interventions in septic shock. Curr Opin Crit Care 2025;epublished July 9th
• Baldetti. Invasive Hemodynamic Monitoring in Acute Heart Failure and Cardiogenic Shock. Rev Cardiovasc Med 2025;26(6):27034
• Tucker. Breathing and balance: Clinical insights and management strategies of respiratory acid‐base disorders. Nutr Clin Pract 2025;40(4):774–792
• Zhang. Distinct Neural Mechanisms Between Anesthesia Induction and Emergence: A Narrative Review. Anesth Analg 2025;141(1):162-171
• Heneghan. Update in clinical science: Autoimmune hepatitis. J Hepatol 2025;82(5):926-937
• Phillips. Cardiac Xenotransplantation: Current State and Future Directions. Circulation 2025;152(1)
• Kim. Clinical benefits and future directions of medium cut-off membranes in hemodialysis: a comprehensive review. Korean J Intern Med 2025;40(4):557-570
• Alberts. Anemia and Transfusion in Infective Endocarditis. Rev Cardiovasc Med 2025;26(6):33394
• Rogers. Diabetes Mellitus in Pregnancy: Implications for Obstetric Anesthesia. Anesthesiology 2025;143(2):424-443

Pre-Clinical

• Wang. Oxidative stress in ARDS: mechanisms and therapeutic potential. Front Pharmacol 2025;16:1603287
• Song. PANoptosis: a new insight into the mechanism of ischaemia–reperfusion injury. Burns Trauma 2025;13:tkaf026

Thursday 10th

Editorials

• Skrifvars. Restrictive Oxygen Use Did Not Improve Outcomes in the UK ROX Study. Acta Scandanavica Anesthesiologica 2025;69(7):e70098
• Augoustides. Scoping Reviews—Understanding their Evolution, Methodology, Context, and Contributions to Systematic Reviews and Meta-Analyses. J Cardiothorac Vasc Anesth 2025;epublished June 13th
• Augoustides. Malperfusion in Acute Type A Dissection – understanding and managing the full implications of the Penn Classification beyond mortality. J Cardiothorac Vasc Anesth 2025;epublished July 9th

Commentaries

• Gruartmoner. Hemodynamic coherence: a metabolic perspective. Crit Care 2025;29:293
• Laurentiu. Climate Change, Emissions of Volatile Anesthetics, and Policy Making: The Case of Desflurane. Anesth Analg 2025;141(1):123-127
• Callaway. Estimating bias from withdrawal of life sustaining treatment in clinical trials. Crit Care 2025;29:288
• Song. What should be done with PEEP during weaning from mechanical ventilation? Crit Care 2025;29(1):283
• Guidet. Balancing our art with our performance. Intensive Care Med 2025;epublished July 7th
• Knowles. Blood transfusion – moving from what to how. Scand J Trauma Resusc Emerg Med 2025;33:118
• Omar. When medicine meets borders: a story of hope, and heartbreak, in the skies. Intensive Care Med 2025;epublished July 10th

Wednesday 9th

Correspondence

• Kirac. Do Eosinopenic Patients With Community-Acquired Pneumonia Really Have a Worse Outcome? Chest 2025;168(1):e15
  • Weckler. Response. Chest 2025;168(1):e15-e16
• Zhong. Driving Health Care Reform to Combat Ventilator-Associated Pneumonia in Low-Resource Settings. Chest 2025;168(1):e16-e17
  • Nemet. Response. Chest 2025;168(1):e17-e18
• Gölcük. Enhancing Prehospital Cricothyrotomy: Addressing Gaps in Indications, Outcomes, and Techniques. Chest 2025;168(1):e18-e19
  • Shekhar. Response. Chest 2025;168(1):e19-e20
• Hockstein. On the Many Ways in Which Paco2 Levels Can Influence Survival for Patients Treated With Extracorporeal CPR. Chest 2025;168(1):e20-e21
  • Izawa. Response. Chest 2025;168(1):e21-e22
• Song. What should be done with PEEP during weaning from mechanical ventilation? Crit Care 2025;29:283
• Lanz. Prehospital thrombolytic treatment of high-risk acute pulmonary embolism. Crit Care 2025;29:284

Case Reports

• Wang. Sudden Right Lower Limb Paralysis. An Uncommon Presentation of Type A Aortic Dissection. Chest 2025;168(1):e1-e2
• Hara. A 72-Year-Old Man With Progressive Dyspnea and Diffuse Lung Disease. Chest 2025;168(1):e3-e7
• Livi. An Unexpected Cause of Postobstructive Pneumonia. Chest 2025;168(1):e9-e13

Tuesday 8th

Research

Randomised Controlled Trials

• Guyette. A Randomized Controlled Trial of Sublingual Sufentanil in Early Management of Pain in Trauma. Anesth Analg 2025;141(1):172-180
• Miyasaka. EEG-Guided Titration of Sevoflurane and Pediatric Anesthesia Emergence Delirium—A Randomized Clinical Trial. JAMA Pediatr 2025;179(7):704-712
• Wijk. Effects of increased cardiopulmonary bypass pump flow on renal filtration, perfusion, oxygenation and tubular injury in cardiac surgical patients - a randomized controlled trial. Anesthesiol 2025;epublished July 7th

Systematic Reviews & Meta Analyses

• Chen. Effects of different respiratory training methods on respiratory function in patients with spinal cord injury: a network meta-analysis of randomized controlled trials. Crit Care 2025;29:285 

Observational Studies

• Jennings. Epidemiology and Mortality of Invasive Staphylococcus aureus Infections in Hospitalized Infants. JAMA Pediatr 2025;179(7):747-755
• Paul. Prolonged Mechanical Ventilation in Critically Ill Patients. Six-Month Mortality, Care Pathways, and Quality of Life. Chest 2025;168(1):106-118
• Trenchat. Self-extubation in critically ill patients: from the French OUTCOMEREA Network. Crit Care 2025;29(1):286
• Coppola. Driving pressure vs. oxygenation-based PEEP titration strategies in ARDS patients: a physiological study. Crit Care 2025;29:28

Guidelines & Position Statements

• Cecconi. Implementing Artificial Intelligence in Critical Care Medicine: a consensus of 22. Crit Care 2025;29:290
• Raina. Liberation from continuous renal replacement therapy due to renal recovery in adults and children: a literature review and Delphi consensus on clinical practice. Crit Care 2025;29:287 

Monday 7th

Narrative Reviews

Clinical

• Aydın. Foundations and Advancements in Hemodynamic Monitoring: Part II - Advanced Parameters and Tools. Turk J Anaesthesiol Reanim 2025;epublished June 17th
• Woodford. Clarity in Hemodynamics and End-Organ Perfusion: Pulsatility, Patient Phenotype, and the Pressure Field as a Novel Approach. Anesth Analg 2025;141(1):113-119
• Gondode. Blockchain in Critical Care. Indian J Crit Care Med 2025; 29 (6):525-530.
• Alvarado-Dyer. Penetrating Brain Injury: Bridging Global Disparities in Care and Advancing Management Strategies. World Neurosurg 2025;199:124110

Sunday 6th

Research

Randomised Controlled Trials

• Miao. Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy: The ANGEL-TNK Randomized Clinical Trial. JAMA 2025;epublished July 5th
• Beynon. Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in India and Tanzania on hospitalisation and mortality: the TIMCI pragmatic cluster randomised controlled trial. eClinicalMedicine 2025;85:103306
• Abdeen. Effects of threshold inspiratory muscle trainer versus trigger sensitivity adjustment versus conventional therapy on respiratory function in mechanically ventilated patients: a randomized controlled trial. Respir Physiol Neurobiol 2025;337:104469

Systematic Reviews & Meta Analyses

• Trelles. Prevalence of invasive fungal infection in critically ill patients: a systematic review and meta-analysis. BMC Infect Dis 2025;25(1):896
• Yuan. Non-invasive neurally adjusted ventilatory assist versus nasal continuous positive airway pressure for premature infants: a systematic review and meta-analysis. Eur J Med Res 2025;30(1):577
• Valladares. Prophylactic Inhaled Antibiotics for Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Incidence and Mortality Outcomes. Lung 2025;203(1):75

Observational Studies

• Sherman. Intravenous fluid bolus resuscitation increases mortality risk in Malawian children with cerebral malaria. Am J Trop Med Hyg 113: 42–48
  • Editorial:  George. Fluid Resuscitation in Pediatric Cerebral Malaria: Insights from the FEAST Trial and Further Evidence from Malawi. Am J Trop Med Hyg 2025;113(1):1–2

Guidelines & Position Statements

• Cryns. The Diagnosis and Treatment of Acute Spinal Cord Injury. Dtsch Arztebl Int 2025;122:219-224
• Latin American Association for the Study of the Liver. ALEH guidance of preoperative care in liver transplantation: referral criteria, patient assessment, and waiting list management. Ann Hepatol 2025;epublished June 28th
• Zhou. Consensus on the Diagnosis and Treatment of Adult Necrotizing Fasciitis (2025 Edition). Burns Trauma 2025;13:tkaf031

Narrative Reviews

Clinical

• Battaglini. Imaging and pulmonary function techniques in ARDS diagnosis and management: current insights and challenges. Crit Care 2025;29:282 
• Szewczyk. Neuromuscular Blocking Agents and Reversal Agents Usage, and Neuromuscular Blockade Monitoring in the Intensive Care Unit. Int J Gen Med 2025:18 3651–3688 
• Börner. The Acute Abdomen: Structured Diagnosis and Treatment. Dtsch Arztebl Int 2025;122:137–144
• Rußwurm. Time-Limited Trials in Intensive Care Medicine: A Tool for Avoiding Inappropriate Treatment. Dtsch Arztebl Int 2025;122:180–185
• Kreimer. Arrhythmogenic Right Ventricular Cardiomyopathy: Diagnosis, Risk Stratification, and Treatment. Dtsch Arztebl Int 2025;122:229–234
• Zumbrunn. The Prognosis After Cardiac Arrest: Evidence on the Short- and Long-Term Course. Dtsch Arztebl Int 2025;122:173–179
• Schneider. Lung Transplantation: Indications, Follow-Up Care and Long-Term Results. Dtsch Arztebl Int 2025;122:43–48
• Alamilla-Sanchez. Understanding Renal Tubular Function: Key Mechanisms, Clinical Relevance, and Comprehensive Urine Assessment. Pathophysiology 2025;32:33
• Carbone. Beyond Mosquitoes: A Review of Pediatric Vector-Borne Diseases Excluding Malaria and Arboviral Infections. Pathogens 2025;14(6):553
• Rodrigues. The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown. Pathogens 2025;14(6):525
• Dumitrascu. Acute Necrotizing Pancreatitis—Advances and Challenges in Management for Optimal Clinical Outcomes. Medicina 2025;61(7):1186
• Jezeršek. Contemporary Practices in Refractory Out-of-Hospital Cardiac Arrest: A Narrative Review. Medicina 2025;61(6):1053
• Sisto. Tissue Doppler Imaging in Acute and Critical Care: Enhancing Diagnostic Precision. Medicina 2025;61(6):1051
• Karimi. Mechanisms of Congestion in Acute Decompensated Heart Failure. Cardiorenal Med 2025;epublished June 28th
• Bernhardt. Clinical Management of the Impella 5.5 Pump. J Heart Lung Transplant 2025;epublished June 24th

Non-Clinical

• Gerß. Introduction to Bayesian Statistics. Dtsch Arztebl Int 2025;122:271–276

Editorials

• Augoustides. Scoping Reviews—Understanding their Evolution, Methodology, Context, and Contributions to Systematic Reviews and Meta-Analyses. J Cardiothorac Vasc Anesth 2025;epublished June 13th
• Bakker. In Memoriam: Rinaldo Bellomo (1956–2025) Senior Editorial Board Member – Journal of Critical Care. J Crit Care 2025;epublished June 13th

Commentaries

• Nedel. Peer review for medical journals: why and how?. Crit Care Sci 2025;37:e20250098
• Mathur. What Every Intensivist Should Know About Remimazolam. Indian J Crit Care Med 2025;29(6):531–533
• Galluzzo. Decongestion strategies in acute heart failure: contrasting opinions from two leading experts. Eur Heart J Acute Cardiovasc Care 2025;14(6):379–381

Correspondence

• Urner. Missing the target in target trial emulation. Crit Care 2025;29:266
• Reddy. User Trust in Artificial Intelligence–Guided Lung Ultrasound. JAMA Cardiol 2025;epublished July 2nd
• Dequin. Correspondence about the article “Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia. The REMAP-CAP corticosteroid domain randomized clinical trial”. Intensive Care Med 2025;epublished July 3rd
• Meng. Computed tomography (CT)-derived skeletal muscle mass and short and long-term mortality in critically ill patients. Crit Care 2025;29:280
• Muñoz. Reply to: Co-existence of congestion and preload-dependence identified by pulse pressure respiratory variations: right ventricular afterload might be the key. Crit Care 2025;29:279
• Honore. Rezafungin: an opportunity to personalize the treatment of patients with candidemia. Crit Care 2025;29:277
• Domínguez de la Cruz. Little Big Issues in Brain–Lung Crosstalk. Am J Respir Crit Care Med 2025;211(7):1317–1318
• Georgopoulos. Reply to Domínguez de la Cruz et al.: Little Big Issues in Brain–Lung Crosstalk. Am J Respir Crit Care Med 2025;211(7):1318–1319

Case Reports

• Hoque. A case of perioperative euglycemic ketoacidosis in a patient without diabetes: are current guidelines enough?. Perioper Med (Lond) 2025;14(1):68
• Painter. Postinfarction Left Ventricular Inferior Wall Aneurysm With Contained Rupture and Tamponade Physiology. JACC Case Rep 2025;30(17):103877
• Kida. Excessive dynamic airway collapse leading to cardiac arrest due to airway obstruction. Acute Med Surg 2025;12(1):e70074
• Hebrard. Traumatic portacaval shunt: a rare complication to be considered in patients with encephalopathy. Trauma Surg Acute Care Open 2025;10:e001706
• Castro Sayat. High-flow nasal therapy versus non-invasive ventilation for AECOPD: navigating beyond a simple choice – are we asking the right questions?. Ann Intensive Care 2025;15:87
• Amiot. Venous Air Embolism Following Intraosseous Access: A Case Report and Echocardiographic Findings. J Am Coll Emerg Physicians Open 2025;6(4):100201
• Varma. Beyond Clots: The Role of Cardiac Anesthesiologists in a Case of ECMO for Massive Pulmonary Embolism. Case Rep Crit Care 2025;2025:5573593
• Kocayiğit. Hemicorporectomy in the ICU: a complex case report. BMC Anesthesiol 2025;25:304
• Dhanasekaran. Question: Silent stenosis to sudden shock: the unplanned culprit. Eur Heart J Acute Cardiovasc Care 2025;14(6):375–376
• Dhanasekaran. Answer: Silent stenosis to sudden shock: the unplanned culprit. Eur Heart J Acute Cardiovasc Care 2025;14(6):377–378

Saturday 5th

Narrative Reviews

Clinical

• Yahya. Maternal Sepsis Review and Update. Mayo Clin Proc 2025;100(7):1212-1230
• Fraisse. Prevention of aspiration pneumonia recurrences. Infect Dis Now 2025;55(6):105102
• Halgas. Hemodynamic Monitoring in Burn Resuscitation: Current Status. Ann Burns Fire Disasters 2025;38(2):91–99
• Tsuchiya. Non-thrombotic pulmonary emboli: imaging findings and differential diagnoses. Jpn J Radiol 2025;epublished
• Mali. Interplay between gut microbiota and acute kidney injury: a review of their mutual influence and causation. Ren Fail 2025;47(1):2522976
• Griva. The role of the tidal volume challenge test in volume responsiveness assessment: a narrative review. J Anesth Analg Crit Care 2025;5:37
• Gameiro. The burden of acute kidney disease: an epidemiological review and importance of follow-up care. Clin Kidney J 2025;18(6):sfaf169
• Roussoulières. Heart Transplant and Durable Mechanical Circulatory Support for Specific Less-Common Cardiomyopathies. CJC Open 2025;7(6):813-820
• Gao. The progress and trends of the mechanism of cardiopulmonary bypass-associated acute lung injury: A narrative review. Medicine 2025;104(26):e43019
• Williams. Future perspectives of heart rate and oxygenation monitoring in the neonatal intensive care unit – a narrative review. J Clin Monit Comput 2025;epublished June 27th
• Magro. Ketamine in Status Epilepticus: How Soon Is Now?. Neurol Int 2025;17(6):83
• Hurley. New perspectives on extracorporeal life support: expert teams and precise selection of candidates are transforming pediatric cancer and hematopoietic cell transplantation care. Front Oncol 2025;15:1588403
• Martin-Loeches. Advocating for the recognition of underlying immunosuppression in critical illness. eClinicalMedicine 2025;85:103300
• Verzár. Nutritional Management of Liver Failure in the Intensive Care Unit. Medicina 2025;61:1210
• Chen. The current status and evolution of hemodialysis catheters. Ren Fail 2025;47(1):2524523
• Dickmann. Sepsis after trauma—evolving paradigms in stress biology and host response failure. Burns Trauma 2025;13:tkaf014
• Via. The liver reconditioning in critical care medicine. Curr Opin Anesthesiol 2025;38(4):523-532
• Schwerk. Post-operative management of children after lung transplantation. JHLT Open 2025;9:100301

Non-Clinical

• Zampieri. Trial Analysis and Interpretation in Critical Care Using the Evidential (Likelihood) Approach: Rationale and Practical Considerations. Am J Respir Crit Care Med 2025;epublished July 1st
• Abbott. Platform trials—an emerging methodology for perioperative medicine: a narrative review. Perioper Med (Lond) 2025;14(1):67

Friday 4th

Research

Randomised Controlled Trials

• Mekontso Dessap. Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL). Intensive Care Med 2025;epublished July 3rd
• Tao. Early Tirofiban Infusion after Intravenous Thrombolysis for Stroke. N Engl J Med 2025;epublished July 3rd
• Hyldegaard. Use of Hyperbaric Oxygen in Patients with Necrotizing Soft Tissue Infections: A Scandinavian Multicenter, Prospective, Observational Cohort. Infect Dis Ther 2025;epublished July 4th
• Li. Nebulization with differently sized 2% lidocaine atomized particles in awake tracheal intubation by video laryngoscopy: a proof-of-concept randomized trial. BMC Anesthesiol 2025;25(1):321

Systematic Reviews & Meta Analyses

• Basmaji. The diagnostic accuracy of point-of-care ultrasound in shock: a systematic review and meta-analysis. Can J Anaesth 2025;epublished July 2nd
• Gao. Noninvasive neuromodulation for disorders of consciousness: an updated systematic review and meta-analysis. Crit Care 2025;29(1):269
• Trelles. Prevalence of invasive fungal infection in critically ill patients: a systematic review and meta-analysis. BMC Infect Dis 2025;25(1):896

Observational Studies

• Hanajima. Early Rehabilitation for Patients with Septic Shock Associated with Mobilization During Their Intensive Care Unit Stay Without Worsening Mortality: A Multicenter, Prospective, Cohort Study. J Intensive Care Med 2025;epublished July 4th
• Meyer. Does the 1:1:1 Transfusion Ratio Mortality Benefit Hold True in Ultra-massive Transfusion? A Study From the Product (Patient Related Outcomes During Ultra-massive transfusion multi-Center Trial) Consortium. Am Surg 2025;epublished July 4th
• Bianchi. Mortality of cancer patients with septic shock: A nation-based cohort analysis of 77,888 patients. Anaesth Crit Care Pain Med 2025;44(5):101557
• Renard. Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial. Anaesth Crit Care Pain Med 2025;44(5):101559
• Torp. Targeted albumin infusions in hospitalized patients with cirrhosis receiving terlipressin: A post-hoc analysis of ATTIRE. Ann Hepatol 2025;epublished July 1st
• Maitland. Early weaning from oxygen therapy in African children with severe pneumonia. BMC Med 2025;23(1):366

Protocols

• Cohen. Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trial. Crit Care Resusc 2025;27(2):100116
• Vignon. Adjunctive dobutamine in patients with septic cardiomyopathy and tissue hypoperfusion: a blinded randomised controlled multicentre trial study protocol of the ADAPT-dobutamine trial. BMJ Open 2025;15(6):e101200

Thursday 3rd

Editorials

• Demiselle. Hemodynamic targets in the initial resuscitation of older patients with sepsis: time for a reappraisal?. Intensive Care Med 2025;epublished July 3rd
• Ostermann. Renal tubular epithelial cells: A revived kidney biomarker?. Intensive Care Med 2025;epublished June 30th
• Vailati. A bundle for thoracic segmental spinal anaesthesia: it is time to move forward!. J Anesth Analg Crit Care 2025;5:35
• Annetta. The never-ending confusion between subclavian vein and axillary vein. J Vasc Access 2025;epublished June 27th
• Malvindi. The 10 Commandments of On-Table Extubation After Cardiac Surgery: Why and How to Increase Adoption. Innovations 2025;epublished June 30th
• Ng. Re-defining ‘clinical reasoning’. Intern Med J 2025;epublished July 1st

Commentaries

• Malyszko. DEFENDER trial: dapagliflozin for critically ill patients with acute organ dysfunction—implications for clinicians. Nephrol Dial Transplant 2025;40(7):1267–1269
• Kellum. Rinaldo Bellomo, MD (1956–2025). Blood Purif 2025;epublished June 26th
• Tripathy. Green intensive care: reimplementing what LMICs have long practised. Lancet Glob Health 2025;13(7):e1166-e1167
• Alghaith. Young ERC Masterclass Journal Club Article: The TOMAHAWK trial. Resuscitation Plus 2025;epublished June 25th

Wednesday 2nd

Research

Randomised Controlled Trials

• Jiao. Randomized Trial of Early vs Standard Renal Replacement Therapy in Patients With Acute Kidney Injury After Type A Aortic Dissection. Ann Thorac Surg 2025;120(1):17-24

Systematic Reviews & Meta Analyses

• Cao. Efficacy and safety of corticosteroids in critically ill patients: a systematic review and meta-analysis. BMC Anesthesiol 2025;25(1):319
• Song. Fluid resuscitation in adults with severe infection and sepsis: a systematic review and network meta-analysis. Front Med (Lausanne) 2025;12:1543586
• Chuang. Diagnostic performances of procalcitonin and C-reactive protein for sepsis: a systematic review and meta-analysis. Eur J Emerg Med 2025;32(4):248-258

Observational Studies

• Serpa-Neto. Regional Practice Variation in the Management of Renal Replacement Therapy Modalities in the STARRT-AKI Trial. Blood Purif 2025;epublished July 1st
• Sunthankar. Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial. Crit Care Med 2025;53(7):e1470-e1480

Tuesday July 1st

Guidelines & Position Statements

• 2025 ESVM Guidelines on interventional treatment of venous thromboembolism. Vasa 2025;epublished June 30th
• Forero-Delgadillo. Colombian consensus on the care of critically ill patients with suspected or confirmed severe yellow fever. Lancet Reg Health Am 2025;48:101144
• Adams. CALM ICU guidelines: Preliminary guidelines on non-pharmacological strategies for agitation in the ICU − A Delphi study. Intensive Crit Care Nurs 2025;90:104135
• Le Marechal. Detection, evaluation and management of the sequelae of infectious encephalitis in adults. Infectious Diseases Now 2025;epublished June 26th

Narrative Reviews

Clinical

• Fujishima. Current corticosteroid therapeutic strategy for community-acquired pneumonia in adults: indications, dosage, and timing. J Intensive Care 2025;13:37 

Monday June 30th

Narrative Reviews

Clinical

• Noor. Point-of-Care Ultrasound Use in Hemodynamic Assessment. Biomedicines 2025;13:1426
• Bignami. ERAS and the challenge of the new technologies. Minerva Anestesiologica 2025 May;91(5):462-71
• van Galen. Artificial Placenta and Artificial Womb Technologies for Lung and Kidney Failure: A Holistic Perspective. ASAIO J 2025;71(7):519-527
• Russotto. Airway management in critically ill patients. BJA Education 2025;epublished June 30th
• Murugaiyan. Current trends in neurocritical care: a comprehensive review. J Neurocrit Care 2025;18(1):1-15

Sunday 29th

Research

Randomised Controlled Trials

• Ozgodek. Acute Normovolemic Hemodilution versus Norepinephrine Infusion During Autologous Blood Donation in Coronary Artery Bypass Graft Surgery: A Prospective Randomized Study. J Cardiothorac Vasc Anesth 2025;epublished June 28th
• Goret. Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications. A Clinical Randomized Trial. Chest 2025;167(6):1727-1736
  • Editorial:  Tetteh. Noninvasive Ventilation for Cardiac Surgical Patients. Reducing Postoperative Complications. Chest 2025;167(6):1528-1529
• Shah. Fifth Centile Versus 50th Centile Mean Blood Pressure Targets in Pediatric Septic Shock: A Randomized Controlled Trial. Crit Care Med 2025;epublished June 16th
• Pasero. Continuous positive airway pressure to prevent reintubation in patients recovering from cardiac surgery: A multicentre randomised clinical trial. Eur J Anaesthesiol 2025;epublished June 27th

Systematic Reviews & Meta Analyses

• Zong. Efficacy and safety of anticoagulation in cardiac arrest: a systematic review and meta-analysis. Emerg Crit Care Med 2025;5(2):109-115
• Rauseo. Opioid sparing anesthesia in cardiac surgery: a meta-analysis. J Cardiothorac Vasc Anesth 2025;epublished June 27th
• de Oliveira. Efficacy of Ramelteon, Suvorexant, and Lemborexant for Delirium Prevention in Hospitalized Patients: A Systematic Review and Meta-Analysis. Crit Care Med 2025;epublished June 13th
• Messina. Effects of intravenous paracetamol on mean arterial pressure in critically ill patients: A systematic review and meta-analysis with trial sequential analysis. Anaesth Crit Care Pain Med 2025;epublished June 25th
• Oslin. Does duration of nimodipine therapy impact outcome in aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis. Neurosurg Rev 2025;48(1):531

Observational Studies

• Izawa. High Normocapnia and Better Functional Outcome in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation After Out-of-Hospital Cardiac Arrest. Chest 2025;167(6):1639-1650
• McGuigan. Arterial CO2 Targets in Veno-Arterial Extracorporeal Membrane Oxygenation After Cardiac Arrest. Chest 2025;167(6):1520-1522
• Shekhar. Prehospital Cricothyrotomy for Emergency Airway Management. Chest 2025;167(6):1684-1686
• CERTAIN Study Investigators. Ventilator-associated pneumonia in low- and middle-income vs high-income countries: the role of ventilator bundle, ventilation practices, and health care staffing. Chest 2025;167:1628-1638
• Serrano-Mayorga. Ventilator-Associated Pneumonia. Bridging Global Disparities Through Standardized Definitions and Transparent Reporting. Chest 2025;167(6):1517-1519
• Rossberg. Quality of Life after Out-of-hospital Cardiac Arrest - A TOMAHAWK Substudy. Eur Heart J Acute Cardiovasc Care 2025;epublished June 25th
• Pontillo. Impact of Cardiopulmonary Bypass Duration on the Renal Effects of Amino Acids Infusion in Cardiac Surgery Patients. J Cardiothorac Vasc Anesth 2025;epublished June 2nd

Guidelines & Position Statements

• JCS/JHRS. JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias. J Arrhythm 2025;41(3):e70033
• Wei. Guideline for antibacterial therapy of adult community-acquired pneumonia in the emergency department under the physician-pharmacist collaborative management model. Emerg Crit Care Med 2025;5(2):65-75

Saturday 28th

Narrative Reviews

Clinical

• Ha Do. Measles 2025. N Engl J Med 2025;epublished June 25th
• Battle. Liver Cirrhosis: Evolving Definitions, and Recent Advances in Diagnosis, Prevention and Management. Livers 2025;5:28
• Rodrigues. Cycle ergometers in extracorporeal membrane oxygenation patient rehabilitation: A scoping review. Aust Crit Care 2025;38(5):101287
• Royz. Respiratory Depression in Non-Operating Room Anesthesia: An Overview. J Clin Med 2025;14(13):4528
• Brouillard. The Next Chapter in TAVR: Innovations and the Road Ahead. J Clin Med 2025;14(13):4504
• Park. Optimizing Airway Function Through Craniofacial and Cervical Manipulations and Emergency-Anesthesia Maneuvers: Applications in Airway Function Enhancement, Pneumonia, and Asthma—Narrative Review. J Clin Med 2025;14(13):4494
• Sisto. Tissue Doppler Imaging in Acute and Critical Care: Enhancing Diagnostic Precision. Medicina (Kaunas) 2025;61(6):1051
• Drugeon. Myths Glorify What Reality Neglects: Efficacy and Safety of Chlorhexidine Gluconate. Curr Infect Dis Rep 2025;27:14
• Petito. VITT Pathophysiology: An Update. Vaccines 2025;13(6):650
• Mourid. Why Pediatric Emergency Departments Are not Ready for Disasters. Curr Emerg Hosp Med Rep 2025;13:16
• Yuen. Bridge to Lung Transplantation Utilizing Extracorporeal Membrane Oxygenation: Consensus and Controversies. Curr Pulmonol Rep 2025;14:13

Editorials

• Landoni. The arc of a life in critical care research—in memory of Professor Rinaldo Bellomo (1956–2025). Signa Vitae 2025;epublished June 17th
• Kentish-Barnes. Palliative care in the ICU: from oxymoron to standard of care. Intensive Care Med 2025;epublished June 25th
• MacLaren. Risk Factors for Stress-related UGIB: More than a Gut Feeling. Am J Respir Crit Care Med 2025;epublished June 25th
• Bellomo. Expanding the critical care collaboration between Australia, New Zealand, and Brazil: The role of journals. Crit Care Resusc 2025;27(2):100114
• Dabla. Transformative impact of point-of-care testing in critical care. World J Crit Care Med 2025;14(2):100623
• Fraser. Animal models of critical care illnesses: current reality, future directions. ICMx 2025;13:65

Commentaries

• Davis. Improvements to out-of-hospital cardiac arrest and opioid overdose treatment algorithms to enhance positive outcomes. Emerg Crit Care Med 2025;5(2):61-64
• Tan. AI ethics for the everyday intensivist. Crit Care Resusc 2025;27(2):100115
• Feng. Clinical trial landscape for pneumonia: Evolving agents against bacterial pathogens. Int J Infect Dis 2025;epublished June 25th

Friday 27th

Case Reports

• Miller. Moral and ethical considerations of early tracheostomy for patients with complete high cervical spinal cord injuries. Trauma Surg Acute Care Open 2025;10(2):e001765
• Cacciapuoti. Allergy, infarction, and stress cardiomyopathy: in-depth analysis of a complex clinical case report. Emerg Crit Care Med 2025;5(2):116-120
• Dost. Stabbed in the back: airway management for penetrating thoracic trauma in the prone position. J Cardiothorac Vasc Anesth 2025;epublished June 27th
• Sahoo. Spontaneous Resolution in Autoimmune Pulmonary Alveolar Proteinosis. A Case Series. Chest 2025;167(6):e177-e181
• Wang. A 47-Year-Old Woman With Recurrent Fever and Productive Cough. Chest 2025;167(6):e183-e188
• Loo. An Older Adult Man With a Massive Pleural Effusion. Chest 2025;167(6)
• Guo. A 54-Year-Old Woman With Recurrent Exertional Dyspnea After Surgical Repair for Atrial Septal Defect. Chest 2025;167(6):e195-e199
• Federbush. Transesophageal Echocardiography and Transesophageal Lung Ultrasound Guided Positive End-Expiratory Pressure Recruitment Maneuver in a Patient With Obesity Requiring Venovenous Extracorporeal Membrane Oxygenation. Chest 2025;167(6):e201-e203

Correspondence

• Collins. Siloed thinking: The case for integrating economic and environmental analysis in critical care. Crit Care Resusc 2025;27(2):100111

Thursday 26th

Correspondence

• Rohrbacher. The use of blood components and their alternatives: a comment. Anaesthesia 2025;epublished June 23rd
• Shah. Clarifying the role of fibrinogen concentrate in major haemorrhage: a reply. Anaesthesia 2025;epublished June 23rd
• Papazisi. Towards a consensus for the definition of vasoplegia in cardiac surgery. J Cardiothorac Vasc Anesth 2025;epublished June 23rd
• Fong. Preoxygenation strategies for intubation: a closer look at inclusion criteria and patient heterogeneity. Lancet Respir Med 2025;13(7):e33
  • Pitre. Preoxygenation strategies for intubation: a closer look at inclusion criteria and patient heterogeneity – Authors' reply. Lancet Respir Med 2025;13(7):e34

Wednesday 25th

Commentaries

• Caplan. Central venous pressure: current uses and prospects for an old parameter. Intensive Care Med 2025;epublished June 25th
• Gaudry. Renal replacement therapy. Intensive Care Med 2025;epublished June 25th
• Healy. Vulnerability through art: a path forward. Intensive Care Med 2025;epublished June 25th

Editorials

• Kentish-Barnes. Palliative care in the ICU: from oxymoron to standard of care. Intensive Care Med 2025;epublished June 25th

Narrative Reviews

Clinical

• Valdez-Resendiz. Perioperative management in acute and chronic spinal cord injury, narrative review. J Anesth Analg Crit Care 2025;5(1):33
• Mukkamala. Intraoperative Hypotension Prediction: Current Methods, Controversies, and Research Outlook. Anesth Analg 2025;141(1):61-73
• Zhang. Distinct Neural Mechanisms Between Anesthesia Induction and Emergence: A Narrative Review. Anesth Analg 2025;141(1):162-171
• Spaar. Safety and efficacy of high frequency jet ventilation: A systematic and narrative review. J Clin Anesth 2025;106:111906
• Diniz. Point-of-care ultrasonography in nephrology: Growing applications, misconceptions and future outlook. World J Nephrol 2025;14(2):105374
• Neumann. Viral factors underlying the pandemic potential of influenza viruses. Microbiol Mol Biol Rev 2025;89:e00066-24
• Shen. The Liver Disease-Related Hypoglycemia: An Overview of the Impact, Management Approaches, and Underlying Mechanisms. Br J Hosp Med 2025;86(6)
• Vakhshoori. Kidney Recovery after Acute Kidney Injury: A Comprehensive Review. Cardiorenal Med 2025;15(1):439-452
• Tang. Lung microbiota: a new hope for treating acute respiratory distress syndrome? Front Microbiol 2025;16:1586949

Non-Clinical

• Mahar. Platform trials: key features, when to use them and methodological challenges. Med J Aust 2025;epublished June 22nd

Tuesday 24th

Research

Randomised Controlled Trials

• Shehabi. Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial. JAMA Surg 2025;epublished June 11th

Systematic Reviews & Meta Analyses

• Diz. Effect of Treatment With Balanced Crystalloids Versus Normal Saline on the Mortality of Critically Ill Patients With and Without Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Anesth Analg 2025;141(1):152-161

Observational Studies

• Holste. Complete AI-Enabled Echocardiography Interpretation With Multitask Deep Learning. JAMA 2025;epublished June 23rd
• Bousquet. Effects of Sevoflurane Inhalation on Pulmonary Hemodynamics in Moderate to Severe Acute Respiratory Distress Syndrome Patients With Septic Shock: A Prospective Cohort Study. Crit Care Med 2025;epublished June 16th
• Dankl. Prognosis of Nonagenarian ICU Patients: A Bayesian analysis of prospective European studies. Ann Intensive Care 2025;15:85

Monday 23rd

Narrative Reviews

Clinical

• Stewart. Initial management of patients with burns and combined injuries for acute care surgeons: What you need to know. J Trauma Acute Care Surg 2025;99(1):10-23
• Rasslan. Management of perforated peptic ulcer: What you need to know. J Trauma Acute Care Surg 2025;99(1):1-9

Guidelines & Position Statements

• Inaba. Evidence-based, cost-effective management of acute diverticulitis. An algorithm of the Journal of Trauma and Acute Care Surgery emergency general surgery algorithms work group. J Trauma Acute Care Surg 2025;99(1):24-28

Editorial

• Huynh. Preoxygenation strategies for endotracheal intubation in resource-limited settings: reframing the basics. Crit Care 2025;29:259 

Sunday 22nd

Narrative Reviews

Clinical

Saturday 21st

Guidelines & Position Statements

Friday 20th

Research

Systematic Reviews & Meta Analyses

Observational Studies

Thursday 19th

Research

Randomised Controlled Trials

Wednesday 18th

Narrative Reviews

Clinical

• Yuriditsky. The latest in the management of pulmonary embolism. Breathe 2025;21(2):240100
• Connerton. Connective tissue disease-associated interstitial lung disease: a rheumatologist's perspective. Breathe 2025;21(2):240166
• Denis. A new era in the treatment of progressive fibrosing interstitial lung diseases. Breathe 2025;21(2):240259
• Motschwiller. Connective tissue disease-related interstitial lung disease and pulmonary hypertension. Breathe 2025;21(2):240173
• Boyle. Systemic autoimmune rheumatic diseases-associated interstitial lung disease: a pulmonologist's perspective. Breathe 2025;21(2):240171
• Marczak. An update on diagnosis and treatments of childhood interstitial lung diseases. Breathe 2025;21(2):250004

Tuesday 17th

Editorials

• Augoustides. Scoping Reviews – understanding their evolution, methodology, context, and contributions to systematic reviews and meta-analysis. J Cardiothorac Vasc Anesth 2025;epublished June 13th
• Augoustides. Emerging Therapeutics in Perioperative Analgesia with Suzetrigine – a novel non-opioid analgesic that blocks voltage-gated sodium channels in peripheral sensory nerves. J Cardiothorac Vasc Anesth 2025;epublished June 13th

Commentaries

• Yamada. Rethinking diuretic use in acute kidney injury: effective prevention or false hope?. J Intensive Care 2025;13:34

Monday 16th

Narrative Reviews

Clinical

• Singh. Perioperative challenges and management strategies for non-cardiac surgery in patients with rheumatic heart diseases: A narrative review. J Anaesthesiol Clin Pharmacol 2025;41(3):384-395
• Orlitová. Right ventricular mechanical support as a bridge to lung transplantation: a literature review of current practices. JHLT Open 2025;epublished June 15th
• Eberlein. Sizing in lung transplantation: principles, practices and ideas for the future. JHLT Open 2025;9:100304
• Ceriani. Point of care ultrasound: focus on evidence for a critical appraisal. Eur J Intern Med 2025;epublished June 16th
• Liu. Advancements, Challenges, and Future Prospects of Nanotechnology in Sepsis Therapy. Int J Nanomedicine 2025;20:7685-7714
• Marhofer. Pediatric Regional Anesthesia: A Practical Guideline for Daily Clinical Practice. Anesthesiology 2025;epublished June 17th

Sunday 15th

Narrative Reviews

Clinical

• Chastain. Adjunctive β-lactams for Staphylococcus aureus bacteremia: a narrative review. Ther Adv Infect Dis 2025;12:20499361251343969
• Ravindranath. Sugammadex for Neuromuscular Blockade Reversal: A Narrative Review. J Clin Med 2025;14:4128
• Mair. The Pathophysiology of Cardiac Troponin Release and the Various Circulating Cardiac Troponin Forms—Potential Clinical Implications. J Clin Med 2025;14:4241

Saturday 14th

Narrative Reviews

Clinical

• Li. Lactate and lactylation in the kidneys: Current advances and prospects (Review). Int J Mol Med 2025;56:121
• Scarlatescu. The Diagnosis of Sepsis-Associated Encephalopathy Using Biomarkers: Are We There Yet? Avicenna J Med 2025;15(2):51-63
• Zhao. Evolving therapeutic strategies for severe fever with thrombocytopenia syndrome: from past to future. Ther Adv Infect Dis 2025;epublished May 16th

Friday 13th

Research

Randomised Controlled Trials

• Chassé. Computed Tomography Perfusion and Angiography for Death by Neurologic Criteria. JAMA Neurol 2025;epublished June 13th
• Bosma. Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation. N Engl J Med 2025;epublished June 13th
• Greco. Effect of Remote Ischemic Preconditioning on Myocardial Injury in Noncardiac Surgery: the PRINCE Randomized Clinical Trial. Circulation 2025;epublished Circulation June 13th
• Maitland. Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis. NEJM 2025;epublished June 13th

Thursday 12th

Research

Randomised Controlled Trials

• McIntyre. A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline. NEJM 2025;epublished June 12th
• Monaco. A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery. N Engl J Med 2025;epublished June 12th
• Martin. Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients. The UK-ROX Randomized Clinical Trial. JAMA 2025;epublished June 12th

Wednesday 11th

Research

Randomised Controlled Trials

• Dres. Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3). Am J Respir Crit Care Med 2025;epublished June 11th
• Summers. Augmented Enteral Protein During Critical IllnessThe TARGET Protein Randomized Clinical Trial. JAMA 2025;epublished June 11th

Tuesday 10th

Narrative Reviews

Clinical

• La Via. Hepatopulmonary syndrome: pathophysiological mechanisms and clinical implications. Curr Opin Anesthesiol 2025;epublished June 10th
• Berger-Estilita. Advancing electroencephalography education in anesthesiology. Curr Opin Anesthesiol 2025;epublished May 26th

Monday 9th

Narrative Reviews

Clinical

Sunday 8th

Research

Randomised Controlled Trials

• Marcucci. Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery. Ann Intern Med 2025;epublished June 3rd
• Jijeh. Optimizing Recovery: Early Versus Delayed Chest Tube Removal in Pediatric Cardiac Surgery Patients: A Randomized Controlled Trial. Crit Care Explor 2025;7(6):e1271
• Oliveira. Enteral versus intravenous antibiotics for critically ill patients: A pilot study. Braz J Infect Dis 2025;29(4):104538
• Ji. Intraoperative oxygen concentration and postoperative delirium in elderly patients undergoing major abdominal surgery: a prospective randomized controlled clinical trial. Int J Colorectal Dis 2025;40(1):137

Systematic Reviews & Meta Analyses

• Alsabri. Outcomes of early high-flow nasal cannula (HFNC) use in pediatric respiratory distress in acute settings: a meta-analysis. Eur J Pediatr 2025;184(7):393
• Killu. The association between integrating echocardiography use in the management of septic shock patients and outcomes in the intensive care unit: a systematic review and meta-analysis. J Ultrasound 2025;28(2):281–294
• Yamamoto. Volatile sedation in critically ill adults undergoing mechanical ventilation: a meta-analysis of randomized controlled trials. Crit Care 2025;29(1):227
• Fluid resuscitation management in patients with sepsis and septic shock: a network meta-analysis. Am J Emerg Med 2025;epublished June 4th
• Annane. Corticosteroids for treating sepsis in children and adults. Cochrane Database Syst Rev 2025;6(6):CD002243
• Acworth. Advanced airway interventions for paediatric cardiac arrest: updated systematic review and meta-analysis. Resusc Plus 2025;23:100963
• Appelbaum. Trauma in pregnancy: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg 2025;epublished May 30th
• Schenck. Systematic review and meta-analysis of transcranial doppler biomarkers for the prediction of delayed cerebral ischemia following subarachnoid hemorrhage. J Cereb Blood Flow Metab 2025;45(6):1031–1047

Observational Studies

• Arabi. Timing of mechanical ventilation and its association with in-hospital outcomes in patients with cardiogenic shock following ST-elevation myocardial infarction: a multicentre observational study. BMJ Open 2025;15(6):e099208
• Al-Salahat. Outcomes of Spinal Cord Infarction with Thrombolysis: A Nationwide Analysis. Neurocrit Care 2025;42:1102–1106
• López-Fernández. The Prevalence and Outcome of Acute Hypoxemic Respiratory Failure (PANDORA) Study in Mechanically Ventilated Children: Prospective Multicenter Epidemiology in Spain, 2019–2021. Pediatr Crit Care Med 2025;26(6):e759–e772
• Andrist. Themes in the Management of Pediatric Brain Death Contestation: Exploratory Qualitative Work From Multidisciplinary Health Professionals in the United States. Pediatr Crit Care Med 2025;26(6):e846–e854
• Wu. A large language model improves clinicians’ diagnostic performance in complex critical illness cases. Crit Care 2025;29:230
• Slater. Long-Term Survival of Children Discharged From Pediatric Intensive Care: A Linked Data Cohort Study. Pediatr Crit Care Med 2025;epublished June 6th
• Fitzgerald. Primary repair versus resection for American Association for the Surgery of Trauma grades I and II colon injuries: Does the management approach really matter? An Eastern Association for the Surgery of Trauma multicenter trial. J Trauma Acute Care Surg 2025;epublished June 6th
• Pontillo. The impact of cardiopulmonary bypass duration on the renal effects of amino acids infusion in cardiac surgery patients. J Cardiothorac Vasc Anesth 2025;epublished June 2nd
• Porter. Beyond Functional Outcomes: Exploring Quality of Life After Critical Illness—A Qualitative Study. Crit Care Med 2025;53(6):e1190–e1201
• Veldeman. The metabolic and autoregulatory profile of reversible delayed cerebral ischemia in unconscious patients after aneurysmal subarachnoid hemorrhage: a prospective multimodal neuromonitoring cohort study. Crit Care 2025;29:228
• Marjanovic. Prevalence, risk factors and consequences of early clinical deterioration under non-invasive ventilation in emergency department patients: a prospective, multicentre, observational study of the French IRU Network. Crit Care 2025;29:224

Protocols

• Hardenberg. Multicentre pragmatic embedded stepped wedge cluster randomised trial comparing glucose 5% with sodium chloride 0.9% as the default drug diluent in the ICU: the sweet-water trial protocol. BMJ Open 2025;15:e097361
• Pannu. Optimization of Inspired Oxygen during Mechanical Ventilation (OPTI-OXYGEN): rationale and design of a pragmatic randomised controlled trial. BMJ Open 2025;15(6):e094924

Guidelines

• Ferrada. Prioritizing circulation over airway to improve survival in trauma patients with exsanguinating injuries: a world society of emergency surgery-panamerican trauma consensus statement. World J Emerg Surg 2025;20(1):47

Narrative Reviews

Clinical

• Coulthard. Leading Diverse Teams in High-Stress Trauma Environments. Curr Trauma Rep 2025;11:12
• Park. Training the next generation of intensivists: Point-of-care ultrasound. J Translational Crit Care Med 2025;7(2):e25-00004
• Wickramasinghe. Predictors of severe leptospirosis: a review. Eur J Med Res 2025;30(1):445
• Miller. Noninvasive Respiratory Support for Pediatric Critical Asthma. Respiratory Care 2025;70(6)
• Merola. Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume. Respir Physiol Neurobiol 2025;336:104454
• Pilipović. Traumatic Brain Injury: Novel Experimental Approaches and Treatment Possibilities. Life 2025;15:884
• Hadweh. Machine Learning and Artificial Intelligence in Intensive Care Medicine: Critical Recalibrations from Rule-Based Systems to Frontier Models. J Clin Med 2025;14(12):4026
• Almudares. Oxygen Saturation Targeting in the Neonatal Intensive Care Unit. J Clin Med 2025;14(11):3975
• Abdeldayem. Antithrombotic Therapy in Acute Coronary Syndrome Patients with End-Stage Renal Disease: Navigating Efficacy and Safety. J Clin Med 2025;14(11):3956
• Oswald. Now and the Future: Medications Changing the Landscape of Cardiovascular Disease and Heart Failure Management. J Clin Med 2025;14(11):3948
• Pellen. Data management and sharing. J Clin Epidemiol 2025;180:111680
• Pryzmont. Biomarkers of traumatic brain injury: narrative review and future prospects in neurointensive care. Front Med 2025;12:1539159
• Saleem-Talib. Leadless pacing: a comprehensive review. Eur Heart J 2025;46(21):1979–1990
• Hooper. To adjust, or not to adjust, for multiple comparisons. J Clin Epidemiol 2025;180:111688

Editorials

• Heringlake. Repetition is unwelcome – but sometimes still instructive. J Cardiothorac Vasc Anesth 2025;epublished June 7th
• Kalin. Delirium After Cardiac Surgery: A Puzzle With Many Pieces. J Cardiothorac Vasc Anesth 2025;epublished June 7th
• Marshall. Vale Professor Rinaldo Bellomo AO. Aus Crit Care 2025;38(4):101283
• Zubair. An Argument for Artificial Intelligence. J Cardiothorac Vasc Anesth 2025;epublished June 6th
• Pirracchio. REMAP-CAP corticosteroids: yet, another swing of the pendulum. Intensive Care Med 2025;epublished June 3rd
• Forni. Rinaldo Bellomo: relentless architect of modern intensive care. Intensive Care Med 2025;epublished June 3rd
• Brasil. The dawn of noninvasive intracranial compliance waveforms: a call for the B-ICONIC improvement and expansion. Intensive Care Med 2025;epublished June 3rd

Commentaries

• Huang. Advancing traditional Chinese medicine for sepsis—challenges beyond clinical evidence. Crit Care 2025;29:222
• Brasil. Monro-Kellie 4.0: moving from intracranial pressure to intracranial dynamics. Crit Care 2025;29:229
• Reep. Effect of initiation of invasive ventilation in acute hypoxemic respiratory failure using sequential trials: treatment efficacy instead of timing. Crit Care 2025;29:221

Correspondence

• Monares Zepeda. Capillary refill time as an additional triage criterion to decide ICU admission of deteriorating obstetric patients. Crit Care 2025;29:231

Case Reports

• Schultz. From Normal to Zero Flow in 30 Seconds on HeartMate 3 LVAD: What Happened? JACC Case Rep 2025;30(13):104248
• Montero-Arias. Diffuse necrotizing pneumonia, cavitations and hemoptysis: A case of sweet syndrome. Respir Med Case Rep 2025;56:102225

Saturday 7th

Narrative Reviews

Clinical

• Lloyd-Donald. Measurement and interpretation of central venous pressure: a narrative review. Anaesthesia 2025;epublished June 3rd
• Mehta. Management of non-Cardiac Organ Failure in cardiogenic shock. Am Heart J Plus 2025;55:100549
• Gando. Disseminated intravascular coagulation. J Intensive Care 2025;13(1):32
• Joffre. Vascular leakage during circulatory failure: physiopathology, impact and treatments. Ann Intensive Care 2025;15(1):79
• Shimizu. Gut dysbiosis and its treatment in patients with critical illness. Acute Med Surg 2025;12(1):e70068
• Nonaka. Right heart failure after left ventricular assist device implantation: latest insights and knowledge gaps on mechanism and prediction. Front Cardiovasc Med 2025;12:1586389
• Kestenbaum. Palliative Care Spiritual Assessment and Goals-of-Care Discussions in the Neurocritical Care Unit: Collaborating with Chaplains. Neurocrit Care 2025;42:780–785
• Takeaki. Probiotic treatment in an intensive care unit: a narrative review. J Intensive Care 2025;13:31
• Verstraete. New horizons in the pharmacological management of venous thromboembolism. HemaSphere 2025;9(6):e70143
• Kelly. Acute Febrile Encephalopathy with Rigidity. J Intensive Care Med 2025;epublished May 30th
• Kumar. Invasive Ventilation Strategies in Neonates. Indian Pediatr 2025;epublished
• Alvitigala. Snakebite-associated acute kidney injury in South Asia: narrative review on epidemiology, pathogenesis and management. Trans R Soc Trop Med Hyg 2025;119(6):648–664

Friday 6th

Guidelines & Position Statements

• Wichmann. Diagnosis and treatment of invasive pulmonary aspergillosis in critically ill intensive care patients: executive summary of the German national guideline (AWMF 113-005). Infection 2025;epublished June 4th
• McKechnie. Airway management in patients living with obesity: best practice recommendations from the Society for Obesity and Bariatric Anaesthesia. Anaesthesia 2025;epublished June 5th

Research

Observational Studies

• McPeake. Top 10 research priorities for sepsis research determined by patients, carers and clinicians. Anaesthesia 2025;epublished June 5th

Thursday 5th

Editorials

• Gauss. From bedside to data and back to bedside: why do we need better data to perform trauma phenotyping and improve trauma care?. Intensive Care Med 2025;epublished June 4th
• Chen. Acute respiratory distress syndrome: Rethinking and research priorities. Chin Med J 2025;epublished June 5th
• Zhang. Immune monitoring in sepsis: Present and prospective issues. Chin Med J 2025;epublished June 5th
• Llompart-Pou. Is There a Place for Cerebrospinal Fluid External Lumbar Drainage in Posttraumatic Intracranial Hypertension? Pros, Cons, and Uncertainties. Neurocrit Care 2025;epublished June 4th
• Spies. Telemedicine in critical care. Intensive Care Med 2025;epublished June 5th
• Li. Perioperative stress, pain, and multimodal analgesia. Chin Med J 2025;epublished June 5th

Correspondence

• Yang. Missing Guidewire in a Bulla: A Case Report. J Chest Surg 2025;epublished June 4th
• Moran. The Stroke Alert that Wasn’t: Lessons Learned from Meningitis-Associated Vasospasm. Neurocrit Care 2025;epublished June 4th

Case Report

• Biebelberg. Shorter antibiotic courses for bloodstream infections can reduce healthcare spending. Intensive Care Med 2025;epublished June 4th

Wednesday 4th

Commentaries

• Walter. Ten tips for managing caustic ingestion in adult patients. Intensive Care Med 2025;epublished June 2nd

Acute Coronary Syndrome Series

• Murugiah. Mechanical Circulatory Support in Acute Myocardial Infarction-Cardiogenic Shock: 2025 Acute Coronary Syndrome Guideline in Context. J Am Coll Cardiol 2025;85(22):2103-2106
• Sawano. The 2025 Guideline for the Management of Patients With Acute Coronary Syndromes: Asian Perspective. J Am Coll Cardiol 2025;85(22):2114–2117
• Bikdeli. Antiplatelet and Anticoagulant Therapy in the 2025 ACC/AHA Guideline for Acute Coronary Syndromes: Key Recommendations. J Am Coll Cardiol 2025;85(22):2074-2078
• Fuster. The Long-Awaited American ACS Guideline: Closer to a Universal Document. J Am Coll Cardiol 2025;85(22):2061–2063
• Yong. A Quarter Century of ACS Guidelines: Gaps Within Evidence Gaps. J Am Coll Cardiol 2025;85(22):2064–2067
• Rao. The 2025 American College of Cardiology/American Heart Association Acute Coronary Syndrome Guideline: A Personal Perspective. J Am Coll Cardiol 2025;85(22):2068–2070
• Lam. Shared Decision Making in the 2025 ACS Guideline. J Am Coll Cardiol 2025;85(22):2071–2073
• Ko. Perspective on the Choice and Duration of Dual Antiplatelet Therapy Recommendations in the 2025 Acute Coronary Syndrome Management Guideline. J Am Coll Cardiol 2025;85(22):2079–2082
• Kaul. The 2025 Guideline Update Endorses Ticagrelor Monotherapy After ≥1 Month of DAPT Post-PCI in Patients With ACS: Is the Evidence Conclusive?. J Am Coll Cardiol 2025;85(22):2083–2087
• Mehran. The 2025 ACS Guideline Update Endorses Ticagrelor Monotherapy ≥1 Month After DAPT Post-PCI: The Unbearable Lightness of Ticagrelor Monotherapy. J Am Coll Cardiol 2025;85(22):2088–2091
• Ridker. Colchicine for Cardiovascular Disease: Navigating the Gap Between Evidence, Guidelines, and Clinical Practice. J Am Coll Cardiol 2025;85(22):2092–2095
• Kaul. Reevaluating Beta-Blocker Recommendations Post-Myocardial Infarction: Perspective on the 2025 Guideline Update. J Am Coll Cardiol 2025;85(22):2096–2099
• Alkhouli. ACS Management Guidelines: Tradition, Innovation, and the Gaps in Between. J Am Coll Cardiol 2025;85(22):2100–2102
• Brandts. Maturation of Lipid Management in the 2025 ACC/AHA Acute Coronary Syndrome Guideline: What It Is and What It Might Have Been. J Am Coll Cardiol 2025;85(22):2107–2110
• Beltrame. The 2025 ACC/AHA Guideline for Acute Coronary Syndromes: A View From Down Under. J Am Coll Cardiol 2025;85(22):2111–2113
• Coughlan. ACS Guidelines: Bridging the Transatlantic Divide. J Am Coll Cardiol 2025;85(22):2118–2121
• Furtado. American College of Cardiology/American Heart Association Acute Coronary Syndrome Guidelines: A Latin American Perspective. J Am Coll Cardiol 2025;85(22):2122–2125
• Kumbhani. 2025 Acute Coronary Syndromes Guideline-at-a-Glance. J Am Coll Cardiol 2025;85(22):2128–2134

Tuesday 3rd

Editorials

• Helms. Corticosteroids in non-viral community-acquired pneumonia: edging closer to “yes”. Intensive Care Med 2025;epublished June 2nd
• Shang. Gut microbiota: A novel target for sepsis treatment. Chin Med J 2025;epublished May 26th
• Tasker. Respiratory Support for Bronchiolitis Management in the PICU: What We Now Know and What We Want to Know. Ped Crit Care Med 2025;26(6):e827-e831
• Smit. Sub-phenotyping in critical care: a valuable strategy or methodologically fragile path?. Intensive Care Med Exp 2025;13(1):59
• Lyons. Rapid sequence induction: a modern-day example of Theseus' Paradox? Anaesthesia 2025;epublished May 25th
• McPhail. Is it time to open the doors of the intensive care unit further for patients with alcohol-related liver disease?. Anaesthesia 2025;epublished May 25th

Monday 2nd

Guidelines & Position Statements

• Xu. Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis. J Clin Transl Hepatol 2025;13(6):516–523
• Piccione. How to Do Echo for Noninvasive Hemodynamic Evaluation of the Patient in the Intensive Care Unit: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging. J Cardiovasc Echogr 2025;35(1):79–90
• Cameli. How to Do Echo in Left Ventricular Assist Device Candidates: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging. J Cardiovasc Echogr 2025;35(1):91–96

Sunday 30th

Narrative Reviews

Clinical

• Greco. Future of factor XI inhibitors in cardiovascular practice. Minerva Cardiol Angiol 2025;73(2):201-218
• Davalan. What Are SAVR Indications in the TAVI Era? J Clin Med 2025;14(7):2357
• Iliakis. Pregnancy-Associated Takotsubo Syndrome: A Narrative Review of the Literature. J Clin Med 2025;14(7):2356
• Piedepalumbo. Safety of steroids in severe community-acquired pneumonia. Eur Respir Rev 2025;34(175):240131
• Demir. Foundations and Advancements in Hemodynamic Monitoring: Part I-Elements of Hemodynamics. Turk J Anaesthesiol Reanim 2025;epublished February 27th
• Carella. Intersections and Challenges in the Management of Acute Coronary Syndrome and Stroke: Pathophysiology, Treatment Dilemmas, and Integrated Prevention Strategies. J Clin Med 2025;14(7):2354
• Li. Advances in sepsis research: Insights into signaling pathways, organ failure, and emerging intervention strategies. Exp Mol Pathol 2025;142:104963
• Nappi. Current Opinion in Acute Aortic Dissection. Cardiol Discov 2025;5(1):69-84
• Daniel. Adjuvant therapies for management of hemorrhagic shock: a narrative review. Crit Care 2025;29:138
• Evanson. Extracranial Effects of Traumatic Brain Injury: A Narrative Review. Clin Pract 2025;15:47
• Carella. Intersections and Challenges in the Management of Acute Coronary Syndrome and Stroke: Pathophysiology, Treatment Dilemmas, and Integrated Prevention Strategies. J Clin Med 2025;14(7):2354
• Lu. Traumatic brain injury: bridging pathophysiological insights and precision treatment strategies. Neural Regen Res 2025;epublished March 25th
• Li. Advances in sepsis research: Insights into signaling pathways, organ failure, and emerging intervention strategies. Exp Mol Pathol 2025;142:104963
• Sen. Hepatic Encephalopathy: Current Thoughts on Pathophysiology and Management. Curr Neurol Neurosci Rep 2025;25(1):28
• Demir. Foundations and Advancements in Hemodynamic Monitoring: Part I-Elements of Hemodynamics. Turk J Anaesthesiol Reanim 2025;epublished February 27th
• Toschi. Recurrence of skin and soft tissue infections: identifying risk factors and treatment strategies. Curr Opin Infect Dis 2025;38(2):71-77
• Piedepalumbo. Safety of steroids in severe community-acquired pneumonia. Eur Respir Rev 2025;34(175):240131
• Zumla. Pleural infection: controversies on the therapeutic strategies. Curr Opin Pulm Med 2025;31(3):218-222
• Greco. Future of factor XI inhibitors in cardiovascular practice. Minerva Cardiol Angiol 2025;73(2):201-218
• Iliakis. Pregnancy-Associated Takotsubo Syndrome: A Narrative Review of the Literature. J Clin Med 2025;14(7):2356
• Davalan. What Are SAVR Indications in the TAVI Era? J Clin Med 2025;14(7):2357
• Lynch. Mechanical Circulatory Support in Congenital Heart Disease. Children 2025;12(3):306
• Musalem. Ten tips for managing complement-mediated thrombotic microangiopathies (formerly atypical hemolytic uremic syndrome): narrative review. BMC Nephrol 2025;26:158
• Harrabi. Suppressive Antibiotic Therapy in Prosthetic Joint Infections: A Contemporary Overview. Antibiotics 2025;14(3):277
• Staub. Neonatal Kidney Function, Injury and Drug Dosing: A Contemporary Review. Children 2025;12:339

Research

Randomised Controlled Trials

• Karkouti. Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery. The FARES-II Multicenter Randomized Clinical Trial. JAMA 2025;epublished March 29th
  • Editorial:  Wang. Is It Time to Replace Plasma With Prothrombin Complex Concentrate in Cardiac Surgery? JAMA 2025;epublished March 29th
• Carver. Ketamine infusion for pain control in severely injured patients: Results of a randomized controlled trial. J Trauma Acute Care Surg 2025;epublished March 28th
• Warner. Practical Anemia Bundle and Hemoglobin Recovery in Critical Illness. A Randomized Clinical Trial. JAMA Netw Open 2025;8(3):e252353
  • Editorial:  Walsh. Active Prevention and Treatment of Post–Critical Illness Anemia—Is It Time for Large Effectiveness Trials? JAMA Netw Open 2025;8(3):e252368
• Smith. A randomised, open-label trial of nebulised unfractionated heparin in patients mechanically ventilated for COVID-19. Anaesth Intensive Care 2025;epublished March 27th
• Tongyoo. Effects of adjunctive milrinone versus placebo on hemodynamics in patients with septic shock: a randomized controlled trial. Ann Med 2025;57(1):2484464
• Posch. Effect of manual decongestive therapy on cardiac preload in critically ill patients: a randomized controlled trial. Ann Intensive Care 2025;15:39
• RECOVERY Collaborative Group. Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. eClinMed 2025;81:103080

Systematic Reviews & Meta Analyses

• Kiss. Combination of urinary biomarkers can predict cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis. Ann Intensive Care 2025;15:45
• Steindl. Hemoadsorption in the Management of Septic Shock: A Systematic Review and Meta-Analysis. J Clin Med 2025;14:2285
• Gu. Glucocorticoids can reduce mortality in patients with severe community-acquired pneumonia: a systematic review and meta-analysis of randomized controlled trials. Eur J Med Res 2025;30(1):215
• Ehrenzeller. Associations Between Prophylactic IV Antibiotics and Outcomes in Patients With Acute Severe Brain Injury Who Require Mechanical Ventilation: Systematic Review and Meta-Analysis. Crit Care Med 2025;epublished March 28th
• Feistritzer. Different Mechanical Circulatory Support Strategies for Infarct-Related Cardiogenic Shock: A Subanalysis of the ECLS-SHOCK Trial. JACC Cardiovasc Interv 2025;18(6):691-701
• Meregildo-Rodriguez. β-lactam antibiotics to prevent ventilator-associated pneumonia (VAP) in coma patients: A systematic review and meta-analysis of randomized controlled trials. Med Intensiva 2025;epublished March 25th
• Gillespie. Hyponatremia Incidence After Subarachnoid Hemorrhage and Association with Outcomes: Systematic Review and Meta-Analysis. World Neurosurg 2025;195:123616
• Alaradi. Incidence of Acute Kidney Injury (AKI) in Critically Ill Patients Receiving Concomitant Vancomycin with Piperacillin-Tazobactam or Cefepime: a Systemic Review and Meta-analysis. J Intensive Care Med 2025;epublished March 23rd
• Ramaswamy. Timing of hydrocortisone therapy in neonates with shock: a systematic review, meta-analysis, and clinical practice guideline. Front Pediatr 2025;13:1491976

Observational Studies

• Ruiz-Bailén. Right Ventricular Strain and Outflow Tract Velocity Time Integral Are Associated with Mortality in Critically Ill Patients with Pulmonary Embolism. Am J Respir Crit Care Med 2025;epublished March 28th
• Phongpreecha. AI-guided precision parenteral nutrition for neonatal intensive care units. Nat Med 2025;epublished March 25th
• Boyle. Evaluation of Plasma Biomarkers to Understand the Biology and Heterogeneity of Treatment Effect in Lower Tidal Volume Ventilation Facilitated by Extracorporeal CO₂ Removal in Acute Hypoxemic Respiratory Failure: A Secondary Analysis of the REST Trial. Crit Care Explor 2025;7(4):e1246
• Dzik. Beyond Hemoglobin Thresholds: A Retrospective Cohort Analysis of RBC Transfusion Decisions in ICU Patients. Crit Care Med 2025;epublished March 28th

Saturday 29th

Guidelines & Position Statements

• Chinese Society of Cardiology. Chinese Guidelines for the Diagnosis and Treatment of Heart Failure 2024. Cardiol Discov 2025;5(1):1-38
• European Society of Cardiology. European Society of Cardiology quality indicators for the management of acute coronary syndromes: developed in collaboration with the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the ESC. Eur Heart J Acute Cardiovasc Care 2025;14(3):145-154
• Flisiak. Management of SARS-CoV-2 Infection—Clinical Practice Guidelines of the Polish Association of Epidemiologists and Infectiologists, for 2025. J Clin Med 2025;14(7):2305

Narrative Reviews

Clinical

• Fatima. Advancements and Challenges in Addressing Zoonotic Viral Infections with Epidemic and Pandemic Threats. Viruses 2025;17(3):352
• Goran. Acute-on-Chronic Liver Failure: Steps Towards Consensus. Diagnostics 2025;15(6):751
• Mućka. Procalcitonin: Infection or Maybe Something More? Noninfectious Causes of Increased Serum Procalcitonin Concentration: Updated Knowledge. Life 2025;15(3):446
• Geremia. Rare or Unusual Non-Fermenting Gram-Negative Bacteria: Therapeutic Approach and Antibiotic Treatment Options. Antibiotics 2025;14(3):306
• Burzyńska. Unveiling Ralstonia spp. in the Neonatal Intensive Care Unit: Clinical Impacts and Antibiotic Resistance. Antibiotics 2025;14(3):259
• Bouzada. Detecting Respiratory Pathogens for Diagnosing Lower Respiratory Tract Infections at the Point of Care: Challenges and Opportunities. Biosensors 2025;15(3):129
• Vajter. Anticoagulation Management During ECMO: Narrative Review. JHLT Open 2025;8:100216
• Coutance. Novel pretransplant desensitization strategies in heart transplantation. JHLT Open 2025;8:100242
• Belal. Providing care for kidney transplant recipients: An overview for generalists. World J Nephrol 2025;14(1):99555
• Brkic. Central Lymphatic Obstruction. Curr Surg Rep 2025;13:17
• Trube. Colchicine therapy in cardiovascular medicine: A literature review. Am Heart J Plus 2025;52:100525
• Tiwari. Insights into medication-induced liver injury: Understanding and management strategies. Toxicol Rep 2025;14:101976
• Maiga. Palliative care in acute care surgery: research challenges and opportunities. Trauma Surg Acute Care Open 2025;10(1):e001615
• Cheungpasitporn. Critical appraisal of systematic reviews and meta-analyses: a step-by-step guide for nephrologists. Renal Fail 2025;47(1):2476736

Friday 28th

Correspondence

• Bihlmaier. Rapid clinical effects of convalescent plasma therapy in severe COVID-19 acute respiratory distress syndrome (ARDS). Intensive Care Med 2025;epublished March 26th
• Sequeira. The Anrep effect in septic shock: a mechanism of cardiac adaptation. Br J Anaesth 2025;134(4):1204-1207
• Lu. Bayesian methods as a complementary tool: balancing innovation and rigor in critical care research. Crit Care 2025;29:135

Case Reports

• Smirnov. Severe Intra- and Post-Operative Lactic Acidosis in a Patient Who Underwent Robotic Thoracoscopic Surgery. Biomedicines 2025;13(3):568
• Gani. Sevoflurane-Associated Acute Liver Injury in Renal Transplantation and Review of Literature. Case Rep Anesthesiol 2025;2025:1303993
• He. Severe pneumonia combined with septic shock caused by community-acquired methicillin-resistant Staphylococcus aureus treated with veno-venous ECMO: A case report. Medicine 2025;104(13):e41627
• Williams. Severe metabolic alkalosis with fludrocortisone therapy—a case report. Emerg Crit Care Med 2025;5(1):57-60

Commentaries

• Rodgers. 7 Takeaways for Primary Care Clinicians From the Updated Acute Coronary Syndromes Guideline. JAMA 2025;epublished March 28th
• Reynolds. Ischaemia with non-obstructive coronary arteries in the 2024 European Society of Cardiology guidelines for the management of chronic coronary syndromes. Eur Heart J Acute Cardiovasc Care 2025;14(3):173-177

Editorials

• Schmidt. The pulmonary artery catheter in modern anesthesiology and intensive care: indications, benefits, and limitations. Braz J Anesthesiol 2025;75(2):844587
• Gembillo. Link between obstructive uropathy and acute kidney injury. World J Nephrol 2025;14(1):99120
• Jaber. Innovations in ICM: transparency, integrity and accessibility. Intensive Care Med 2025;epublished March 26th
• Erdoes. The Next Wave: Are We Prepared for Patients on Anticoagulation With Factor XI Inhibitors in Cardiac Surgery? J Cardiothorac Vasc Anesth 2025;epublished March 3rd

Thursday 27th

Narrative Reviews

Clinical

• Berry. Lung Ultrasound in Critical Care: A Narrative Review. Diagnostics 2025;15(6):755
• Depta. Expiratory time constants in mechanically ventilated patients: rethinking the old concept-a narrative review. Intensive Care Med Exp 2025;13(1):40

Editorials

• Corradi. The Doppler combined assessment of splanchnic perfusion and congestion in cardiogenic shock: a physiological approach. Intensive Care Med 2025;epublished March 26th

Wednesday 26th

Research

Randomised Controlled Trials

• Han. Care guided by tissue oxygenation and haemodynamic monitoring in off-pump coronary artery bypass grafting (Bottomline-CS): assessor blind, single centre, randomised controlled trial. BMJ 2025:388:e082104
• Albert. Vasopressin and Steroids in addition to Adrenaline in Cardiac Arrest (VAST-A) – A Randomised Pilot Study. Resuscitation 2025;epublished March 26th

Systematic Reviews & Meta Analyses

• Ren. Clearing the path: Hypertonic saline's impact on intracranial pressure in traumatic brain injury. A systematic review and meta-analysis. Adv Clin Exp Med 2025;epublished March 24th
• Qi. Selection of timing of continuous renal replacement therapy in patients with acute kidney injury: A meta-analysis of randomized controlled trials. PLoS One 2025;20(3):e0320351
• Jivraj. Intra-operative ventilation strategies and their impact on clinical outcomes: a systematic review and network meta-analysis of randomised trials. Anaesthesia 2025;epublished March 25th
• Barbosa. Dexmedetomidine for Prevention of Postoperative Delirium in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Curr Anesthesiol Rep 2025;15:37
• Kalakoutas. The association of fluid balance with traumatic brain injury outcomes: A systematic review. J Intensive Med 2025;epublished March 24th

Observational Studies

• Goldsweig. Blood Transfusion in Patients With Acute Myocardial Infarction, Anemia, and Heart Failure: Lessons From MINT. Circ Heart Fail 2025;epublished March 26th
• Dupont. Amikacin use in critically ill patients requiring renal replacement therapy: the AMIDIAL-ICU study. Ann Intensive Care 2025;15(1):42
• Feistritzer. Different Mechanical Circulatory Support Strategies for Infarct-Related Cardiogenic Shock: A Subanalysis of the ECLS-SHOCK Trial. J Am Coll Cardiol Intv 2025;18(6):691-701
• Johnson. Risk Factors for Health Care–Associated Bloodstream Infections in NICUs. JAMA Netw Open 2025;8(3):e251821
• Elmer. Recovery Potential in Patients After Cardiac Arrest Who Die After Limitations or Withdrawal of Life Support. JAMA Netw Open 2025;8(3):e251714
• Lee. Five-Year Functional Outcomes Among Patients Surviving Aneurysmal Subarachnoid Hemorrhage. JAMA Netw Open 2025;8(3):e251678
  • Editorial:  Volovici. Long-Term Outcomes After Subarachnoid Hemorrhage—The Road to Recovery Is Longer Than Expected. JAMA Netw Open 2025;8(3):e251686
• Massart. Selective decontamination regimens in French ICUs: association with reduced infection and resistance emergence. Ann Intensive Care 2025;15(1):41
• Nguyen. Packed red blood cell transfusion: a catalyst for thrombosis in patients with traumatic brain injury? Brain Inj 2025;epublished March 24th
• Mian. Prophylactic antibiotic use in trauma patients with non-operative facial fractures: A prospective AAST multicenter trial. J Trauma Acute Care Surg 2025;98(4):557-564

Tuesday 25th

Research

Randomised Controlled Trials

• Han. Care guided by tissue oxygenation and haemodynamic monitoring in off-pump coronary artery bypass grafting (Bottomline-CS): assessor blind, single centre, randomised controlled trial. BMJ 2025:388:e082104

Guidelines & Position Statements

• The Australasian Society of Parenteral and Enteral Nutrition: Consensus statements on refeeding syndrome. Nutrition & Dietetics 2025;epublished March 16th
• Kühne. Criteria for trauma team activation and staffing requirements for the management of patients with (suspected) multiple and/or severe injuries in the resuscitation room– a systematic review and clinical practice guideline update. Eur J Trauma Emerg Surg 2025;51:142
• American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Carbon Monoxide Poisoning. A Critical Issue in the Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning. Ann Emerg Med 2025;85(4):e45-e59
• Disparities in Current Pulmonary Embolism Management and Outcomes: A Scientific Statement From the American Heart Association. Circulation 2025;epublished March 20th

Narrative Reviews

Clinical

• Haddad. Continuous Renal Replacement Therapy in Children. Indian Pediatr 2025;epublished March 21st
• He. Molecular mechanisms and therapeutic interventions in acute kidney injury: a literature review. BMC Nephrol 2025;26(1):144

Commentaries

• Nallasamy. Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be Used in Children with Septic Shock? Yes. Indian Pediatr 2025;62:233–235
• Samprathi. Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be used in Children with Septic Shock? No. Indian Pediatr 2025;62:229–231

Monday 24th

Narrative Reviews

Clinical

• Kim. Recent Advances in Prehospital and In-Hospital Management of Patients with Severe Trauma. J Clin Med 2025;14:2208
• Montoto-Marqués. Advances and New Therapies in Traumatic Spinal Cord Injury. J Clin Med 2025;14:2203
• Cioboata. Coinfections in Tuberculosis in Low- and Middle-Income Countries: Epidemiology, Clinical Implications, Diagnostic Challenges, and Management Strategies—A Narrative Review. J Clin Med 2025;14:2154
• Testoni. Endoscopic Management of Recurrent Acute Pancreatitis. J Clin Med 2025;14:2150
• Parreira. Penetrating cardiac injuries: What you need to know. J Trauma Acute Care Surg 2025;98(4):523-532
• Maurer. Sepsis management of the acute care surgery patient: What you need to know. J Trauma Acute Care Surg 2025;98(4):533-540
• Russell. Cervical spine clearance in the pediatric trauma population: What you need to know. J Trauma Acute Care Surg 2025;98(4):541-549

Sunday 23rd

Research

Randomised Controlled Trials

• Bentridi. Midline Venous Catheter vs Peripherally Inserted Central Catheter for Intravenous Therapy: A Randomized Clinical Trial. JAMA Netw Open 2025;8(3):e251258
• Paje. The Achilles’ Heel of Midline Catheters. JAMA Netw Open 2025;8(3):e251268
• Agbontaen. Artificial Intelligence Guided Bronchoscopy is Superior to Human Expert Instruction for the Performance of Critical-Care Physicians: A Randomized Controlled Trial. Crit Care Med 2025;epublished March 20th
• Othman. Combined ketamine and midazolam vs. midazolam alone for initial treatment of pediatric generalized convulsive status epilepticus (Ket-Mid study): A randomized controlled trial. Pediatr Neurol 2025;epublished March 21st
• Li. A phase III, randomized, controlled noninferiority trial to study the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) vs piperacillin/tazobactam (PIP/TAZ) in patients with hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP). Int J Infect Dis 2025;153:107357

Systematic Reviews & Meta Analysis

• Cheng. Haloperidol in treating delirium, reducing mortality, and preventing delirium occurrence: Bayesian and frequentist meta-analyses. Crit Care 2025;29:126
• Alilou. Intraosseous versus intravenous vascular access in out-of-hospital cardiac arrest: a systematic review and meta-analysis of randomized controlled trials. Crit Care 2025;29:124
• Yamamaoto. High-density enteral formula in critically ill pediatric patients: a systematic review and meta-analysis. Clin Nutr ESPEN 2025;epublished March 18th
• Jiménez Franco. Mortality in Critically Ill Patients with Liberal Versus Restrictive Transfusion Thresholds: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis. J Clin Med 2025;14:2049
• Fukunaga. Prevalence, risk factors, and treatment methods of thirst in critically ill patients: A systematic review and meta-analysis. PLoS One 2025;20(3):e0315500

Observational Studies

• Zhuang. An ICU-grade breathable cardiac electronic skin for health, diagnostics, and intraoperative and postoperative monitoring. Sci Adv 2025;11(12):eadu3146
• Young. Mean arterial pressure targets in intensive care unit patients receiving noradrenaline: An international survey. Crit Care Resusc 2025;27(1):100095
• Varis. Clinical outcomes and peripheral tissue oxygen saturation monitoring of the knee region by near-infrared spectroscopy in circulatory shock: a prospective observational cohort study. Crit Care 2025;29:125
• Nitayavardhana. Streamlining data recording through optical character recognition: a prospective multi-center study in intensive care units. Crit Care 2025;29:117
• Murphy. The Apnea Interval: Ventilation interruption during tracheal intubation and its association with cardiac arrest resuscitation care and outcome. Resuscitation 2025;epublished March 17th
• Sarma. Association between vasopressin administration and mortality in patients with cardiogenic shock. Am Heart J 2025;epublished March 20th

Protocols

• Granholm. INCEPT: The Intensive Care Platform Trial—Design and protocol. Acta Anaesth Scand 2025;epublished March 14th
• Monti. Pirfenidone to prevent fibrosis in acute respiratory distress syndrome: The PIONEER study protocol. Contemp Clin Trials 2025;epublished March 14th
• Horstink. Standard versus double dosing of beta-lactam antibiotics in critically ill patients with sepsis: The BULLSEYE study protocol for a multicenter randomized controlled trial. BMC Infect Dis 2025;25:392

Narrative Reviews

Clinical

• Ramos. Practical approaches to the tasks of preserving autonomy and respecting vulnerability among critically ill adult patients: a narrative review. Crit Care Sci 2025;37:e20250234
• Chua. The role of artificial intelligence in sepsis in the Emergency Department: a narrative review. Ann Transl Med 2025;13(1):4
• Tepetes. Transition to Advanced Heart Failure: From Identification to Improving Prognosis. J Cardiovasc Dev Dis 2025;12:104
• Hancock. Deciphering sepsis: transforming diagnosis and treatment through systems immunology. Front Sci 2025;2:1469417
• Anand. Rethinking Balanced Resuscitation in Trauma. J Clin Med 2025;14:2111
• Gelpi. Kidney Transplant: More than Immunological Problems. J Clin Med 2025;14:2101
• Ekong. Status asthmaticus and the use of ketamine nebulization and magnesium sulfate: current strategies and outcomes. Ann Med Surg 2025;87(2):650-657
• Khwaja. Unraveling Ventilator-Induced Diaphragmatic Dysfunction: A Comprehensive Narrative Review on Pathogenesis, Diagnosis and Management of Ventilator-Induced Diaphragmatic Dysfunction. Physiother Res Int 2025;30(2):e70046
• Profili. Sodium–Glucose Cotransporter-2 Inhibitors After Acute Myocardial Infarction. Biomedicines 2025;13:720
• Deshwal. Pulmonary veno-occlusive disease: a clinical review. Breathe 2025;21(1):240098
• Ong. Cardiovascular–obstetric state-of-the-art review: pulmonary hypertension in pregnancy. Singapore Med J 2025;66(3):130-140
• Gamarra. Ultrasound imaging of congestion in heart failure: a narrative review. Cardiovasc Diagn Ther 2025;15(1):233-250
• Andrei. Efficacy of Neurorehabilitation Approaches in Traumatic Brain Injury Patients: A Comprehensive Review. Life 2025;15:503
• Mokra. N-Acetylcysteine in the Treatment of Acute Lung Injury: Perspectives and Limitations. Int J Mol Sci 2025;26:2657
• Gadour. Lesson learnt from 60 years of liver transplantation: Advancements, challenges, and future directions. World J Transplant 2025;15(1):93253

Editorials

• Sonneville. Triggers of viral encephalitis: a brain teaser to be solved!. Ann Intensive Care 2025;15:31
• Besen. Brazilian joint statement on the management of mechanically ventilated patients: where did we come from? Where should we go? Crit Care Sci 2025;37:e20250028
• Young. Excessive vasopressors or excessive hypotension: Searching for the goldilocks zone in mean arterial pressure targets. Crit Care Resusc 2025;27(1):100101
• Lyons. Airway fires during use of high-flow nasal oxygen: a cause for concern. Br J Anaesth 2025;134(4):893-897
• Guzzi. Non–ST-Segment Elevation Myocardial Infarction in the Elderly: Is Medicine the Best Medicine? J Cardiothorac Vasc Anesth 2025;epublished February 27th
• Min. Does benzodiazepine-free cardiac anesthesia reduce postoperative delirium? J Cardiothorac Vasc Anesth 2025;epublished March 21st

Commentaries

• Diniz-Silva. Application of new ARDS guidelines at the bedside. Crit Care Sci 2025;37:e20250171
• Ladell. The problem with how we view medical (and diagnostic) error in emergency medicine. Acad Emerg Med 2025;32(3):340-347
• Pelaccia. Diagnostic reasoning and cognitive error in emergency medicine: Implications for teaching and learning. Acad Emerg Med 2025;32(3):320-326
• Taylor. Leveraging artificial intelligence to reduce diagnostic errors in emergency medicine: Challenges, opportunities, and future directions. Acad Emerg Med 2025;32(3):327-339
• Ho. Liberal Versus Restrictive Transfusion Trigger after Acute Brain Injury: More than Just Higher Blood Oxygen Content. Neurocrit Care 2025;epublished March 19th
• Kwong. Management of ascites and volume overload in patients with cirrhosis. Clin Liver Dis 2025;23(1):e0115

Correspondence

• Bottari. Rethinking caution: a critical appraisal of extracorporeal blood purification in sepsis. Crit Care 2025;29:123
• Wang. Questioning the classification of "high blood flow" versus "low blood flow" ECCO₂R in ultra-low tidal volume ventilation studies: a call for functional classification. Crit Care 2025;29(1):121
• Dionnel. Early exercise therapy in patients with severe traumatic spinal cord injury: is it feasible in the ICU?. Crit Care 2025;29:120
• Zijlstra. The sicker the patient, the higher the mortality. Crit Care 2025;29:118
• Fajardo-Campoverdi. Stress, strain and mechanical power: let's not forget the shape of the flow. Anaesthesia 2025;epublished March 17th

Saturday 22nd

Narrative Reviews

Clinical

• Lenarczyk. Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures. Nat Rev Cardiol 2025;22(4):273-303
• Waalders. Haemoadsorption to remove inflammatory mediators in sepsis: past, present, and future. ICMx 2025;13:38
• Rietveld. Let’s get in sync: current standing and future of AI-based detection of patient-ventilator asynchrony. ICMx 2025;13:39

Friday 21st

Research

Randomised Controlled Trials

• George. Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial. Lancet Respir Med 2025;epublished March 21st
  • Commentary:  Alexander. Nasal high-flow oxygen for apnoeic oxygenation during emergency endotracheal intubation of children. Lancet Respir Med 2025;epublished March 21st

Systematic Reviews & Meta Analyses

• Lee. Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection. A Systematic Review and Noninferiority Meta-Analysis. JAMA Netw Open 2025;8(3):e251421
• Pitre. Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials. Lancet Respir Med 2025;epublished March 21st
  • Commentary:  Myatra. Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask? Lancet Respir Med 2025;epublished March 21st

Guidelines & Position Statements

• Sonneville. Management of severe acute encephalopathy in the ICU: an expert consensus statement from the french society of intensive care medicine. Ann Intensive Care 2025;15:37
• Nakamura. The Japanese Critical Care Nutrition Guideline 2024. J Intensive Care 2025;13:18

Narrative Reviews

Clinical

• Benites. Ventilation-induced acute kidney injury in acute respiratory failure: Do PEEP levels matter?. Crit Care 2025;29:130

Thursday 20th

Editorials

• Mongodi. How we use critical care ultrasound in the management of ventilatory settings in ARDS patients. Intensive Care Med 2025;epublished March 20th

Guidelines & Position Statements

• Ventricular arrhythmias in acute heart failure. A clinical consensus statement of the Association for Acute CardioVascular Care (ACVC), the European Heart Rhythm Association (EHRA) and the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 2025;epublished March 19th

Narrative Reviews

Clinical

• Sootlek. Electrical impedance tomography in critical care: Advancing bedside respiratory monitoring and ventilation management: Electrical impedance tomography in critical care. Clin Crit Care 2025;33(1):e250008
• Bracey. Managing Acute Respiratory Failure With Facemask Noninvasive Ventilation. Ann Emerg Med 2025;85(4):349-354

Wednesday 19th

Guidelines & Position Statements

• Blood Culture–Negative Endocarditis: A Scientific Statement From the American Heart Association: Endorsed by the International Society for Cardiovascular Infectious Diseases. J Am Heart Assoc 2025;epublished March 17th
• 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on the Evaluation and Management of Cardiogenic Shock: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol 2025;epublished March 17th

Narrative Reviews

Clinical

• Adhikari. Assessment and management of dengue. BMJ 2025;388:e082639
• Jendoubi. Optimising fluid therapy during venoarterial extracorporeal membrane oxygenation: current evidence and future directions. Ann Intensive Care 2025;15:32
• Baker. Adding insult to injury: the spectrum of tubulointerstitial responses in acute kidney injury. J Clin Invest 2025;135(6):e188358
• Rapti. The Evolving Landscape of Infective Endocarditis: Difficult-to-Treat Resistance Bacteria and Novel Diagnostics at the Foreground. J Clin Med 2025;14:2087

Pre-Clinical

• Flower. Role of inflammasomes in acute respiratory distress syndrome. Thorax 2025;80:255-263
• Chen. Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy. Sig Transduct Target Ther 2025;10:, 90

Tuesday 18th

Narrative Reviews

Clinical

• Oami. Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets. J Intensive Care 2025;13:16
• Simpson. Long-Term Complications Related to Cardiac Implantable Electronic Devices. J Clin Med 2025;14:2058
• Zernini. Acute Respiratory Distress Syndrome and Fluid Management: Finding the Perfect Balance. J Clin Med 2025;14(6):2067
• Montalto. Heart Failure in Older Patients: An Update. J Clin Med 2025;14:1982

Research - ISICEM Meeting

Randomised Controlled Trials

• Jabaudon. Inhaled Sedation in Acute Respiratory Distress SyndromeThe SESAR Randomized Clinical Trial. JAMA 2025;epublished March 18th
  • Editorial: Venkatesh. Sevoflurane Sedation in Acute Respiratory Distress SyndromeTime to Put It to Sleep. JAMA 2025;epublished March 18th

Observational Studies

• Kalimouttou. Optimal Vasopressin Initiation in Septic Shock. The OVISS Reinforcement Learning Study. JAMA 2025;epublished March 18th
• Taran. Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies. Lancet Respir Med 2025;epublished March 17th

Research

Randomised Controlled Trials

• Courtright. Nudging Clinicians to Promote Serious Illness Communication for Critically Ill Patients: A Pragmatic Cluster Randomized Trial. JAMA Intern Med 2025;epublished March 17th
• Zhao. High-dose intravenous vitamin C reduce C-reactive protein levels, fluid retention, and APACHE II scores in patients with moderately severe acute pancreatitis: a prospective, randomized, double-blinded, placebo-controlled study. Ann Intensive Care 2025;15:30

Observational Studies

• Nitayavardhana. Streamlining data recording through optical character recognition: a prospective multi-center study in intensive care units. Crit Care 2025;29:117
• Asif. Evolution of Spinal Cord Swelling in Acute Traumatic Spinal Cord Injury. Neurotrauma Reports 2025;epublished February 12th

Monday 17th

Narrative Reviews

Clinical

• Yang. Advances in rhabdomyolysis: A review of pathogenesis, diagnosis, and treatment. Chin J Traumatol 2025;epublished February 27th
• Manzi. Acute Heart Failure and Non-Ischemic Cardiomyopathies: A Comprehensive Review and Critical Appraisal. Diagnostics (Basel) 2025;15(5):540
• Rhee. Dialysis decision in critically ill patients in intensive care unit. Acute Crit Care 2025;40(1):1-9
• Di Cristo. Hemodynamic Effects of Positive Airway Pressure: A Cardiologist’s Overview. J Cardiovasc Dev Dis 2025;12:97
• Koratala. Hepatocardiorenal Syndrome: Integrating Pathophysiology with Clinical Decision-Making via Point-Of-Care Ultrasound. Cardiorenal Med 2025;15(1):184-197
• Dusi. The role of antiarrhythmic drugs and stellate ganglion block in the acute management of electrical storm. Eur Heart J Suppl 2025;27(Suppl 1):i154-i161
• Olie. Diagnosing infectious encephalitis: a narrative review. Clin Microbiol Infect 2025;31(4):522-528

Sunday 16th

Narrative Reviews

Clinical

• Casey. Current views on paediatric phaeochromocytoma and paraganglioma with a focus on newest guidelines. Best Pract Res Clin Endocrinol Metab 2025;39(1):101957
• Maris. Drug-Induced Liver Injury-Pharmacological Spectrum Among Children. Int J Mol Sci 2025;26(5):2006
• Ramly. Anesthetic Techniques and Cancer Outcomes: What Is the Current Evidence? Anesth Analg 2025;140(4):768-777
• Horine. Perioperative Pain Management in Patients With Cancer-Related Pain: A Narrative Review. Anesth Analg 2025;140(4):833-845
• Perry. Cancer Biology and the Perioperative Period: Opportunities for Disease Evolution and Challenges for Perioperative Care. Anesth Analg 2025;140(4):846-859
• Deshpande. Cancer-Related Coagulopathy and Perioperative Considerations. Anesth Analg 2025;140(4):860-872
• Kano. Strategies to Maximize the Benefits of Evidence-Based Enteral Nutrition: A Narrative Review. Nutrients 2025;17(5):845
• Al Qahtani. Nutrition Support Therapy for Hospitalized Children with Malnutrition: A Narrative Review. Healthcare (Basel) 2025;13(5):497
• Martínez-Torija. Multifaceted Pathophysiology and Secondary Complications of Chronic Spinal Cord Injury: Focus on Pressure Injury. J Clin Med 2025;14(5):1556
• Lee. Selenium as an Antioxidant: Roles and Clinical Applications in Critically Ill and Trauma Patients: A Narrative Review. Antioxidants 2025;14:294
• Lee. Transforming rapid response team through artificial intelligence. Acute Crit Care 2025;40(1):136-137
• Karnwal. Addressing the global challenge of bacterial drug resistance: insights, strategies, and future directions. Front Microbiol 2025;16:1517772
• Vail. Best Practices for Hospital-Based Donor Care Unit Operations. CHEST Crit Care 2025;epublished March 3rd
• Vail. How I Do It: Part 1: Best Practices for Intensivists Planning and Opening Hospital-Based Deceased Organ Donor Care Units. CHEST Crit Care 2025;3:100110
• Dusi. The role of antiarrhythmic drugs and stellate ganglion block in the acute management of electrical storm. Eur Heart J Suppl 2025;27(Suppl 1):i154-i161
• De Caterina. Over 10 years of non-vitamin K antagonist oral anticoagulants: highlights, challenges, and future developments. Eur Heart J Suppl 2025;27(Suppl 1):i6-i11
• Ewing. Review of organ damage from COVID and Long COVID: a disease with a spectrum of pathology. Med Rev 2025;5(1):66-75

Saturday 15th

Research

Randomised Controlled Trials

• Kasner. Critical Care Decisions After Large Core Cerebral Infarctions: A Secondary Analysis From the SELECT2 Trial. Ann Neurol 2025;97(4):698-708
• Kulkarni. Infections in Standard or Tapered Dose of Prednisolone for Alcohol-Associated Hepatitis: A Randomized Trial (STASH Trial). Am J Gastroenterol 2025;epublished March 13th
• Major Extremity Trauma Research Consortium (METRC). Oral vs Intravenous Antibiotics for Fracture-Related Infections: The POvIV Randomized Clinical Trial. JAMA Surg 2025;160(3):276-284
• Jia. Remote ischaemic pre-conditioning, kidney injury, and outcomes after coronary angiography and intervention: a randomized trial. Eur Heart J 2025;epublished March 11th

Systematic Reviews & Meta Analyses

• Zhao. Lactated Ringer's solution versus saline fluid resuscitation for reducing progression to moderate-to-severe acute pancreatitis: a systematic review and meta-analysis. Int J Surg 2025;epublished March 14th
• Boukhlik. Evaluation of efficacy and safety of perioperative albumin administration in major non-cardiac surgery: a systematic review and meta-analysis of randomized controlled trials. Minerva Surg 2025;80(1):76-85
• Biancari. How Long Should Patients Be Treated With Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation? Individual Patient Data Pooled Analysis. Crit Care Med 2025;epublished February 18th

Observational Studies

• Gharaibeh. Impact of initial jugular vein insertion site selection for central venous catheter placement on hemodialysis catheter complications. J Crit Care 2025;87:155011
• Chong. Clinical outcomes of hypertonic saline vs mannitol treatment among children with traumatic brain injury. JAMA Netw Open 2025;8(3):e250438
• Laws. The Path From Intracranial Pressure to Clinical Outcomes in Pediatric Traumatic Brain Injury. JAMA Netw Open 2025;8(3):e250446
• Rousseau. Short-Term Safety and Effectiveness for Tenecteplase and Alteplase in Acute Ischemic Stroke. JAMA Netw Open 2025;8(3):e250548
• Zheng. Causes and impacts of interrupted enteral nutrition in critically ill patients: A secondary analysis of a cluster-randomized controlled trial. Nurs Crit Care 2025;30(2):e70006
• Thevathasan. Association of Electrocardiographic Patterns After Successfully Resuscitated Out-of-Hospital Cardiac Arrest With Significant Coronary Lesions and Mortality—A Predefined Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation (TOMAHAWK) Trial. Crit Care Med 2025;epublished February 24th
• Liu. Phenotypes of Functional Decline or Recovery in Sepsis ICU Survivors: Insights From a 1-Year Follow-Up Multicenter Cohort Analysis. Crit Care Med 2025;epublished February 24th

Guidelines & Position Statements

• American Society of Hematology. Living guidelines on use of anticoagulation for thromboprophylaxis for patients with COVID-19: executive summary. Blood Adv 2025;9(6):1247-1260
• Darfelt. Consensus statements on end-of-life care in ICU - A Scandinavian multidisciplinary Delphi study. Acta Anaesthesiol Scand 2025;69(4):e70015
• Xu. Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024). J Clin Transl Hepatol 2025;13(3):253-267

Friday 14th

Editorials

• Pisano. The Pitfalls of Comparing Different Mechanical Circulatory Support Modalities. J Cardiothorac Vasc Anesth 2025;epublished March 12th
• Thomas. Plasma exchange to treat liver failure: The field expands. Indian J Gastroenterol 2025;epublished March 10th
• Holloway. Incremental Value of Transesophageal Echocardiographic Imaging in Durable Left Ventricular Assist Device Patients – A Novel Approach Worth Considering. J Cardiothorac Vasc Anesth 2025;epublished March 12th
• Doblas. Weaning From Mechanical Ventilation in Chronic Critically Ill Patients. Arch Bronconeumol 2025;epublished February 12th
• Lee. Transforming rapid response team through artificial intelligence. Acute Crit Care 2025;40(1):136-137

Commentaries

• Yang. The promise of transcranial focused ultrasound in disorders of consciousness: a narrative review. Crit Care 2025;29:109
• Hodkinson. Pre-hospital emergency anaesthesia in 2025: ten years on from the modification of induction regimes. Scand J Trauma Resusc Emerg Med 2025;33:42
• Kotecha. The ‘10 commandments’ for the 2024 European Society of Cardiology guidelines on atrial fibrillation. Eur Heart J 2025;46(11):996-998

Correspondence

• Holloway. Incremental Value of Transesophageal Echocardiographic Imaging in Durable Left Ventricular Assist Device Patients – A Novel Approach Worth Considering. J Cardiothorac Vasc Anesth 2025;epublished March 12th
• Gilrane. Prevention and Risk for Extubation Respiratory Failure. Obesity, A New Protective Phenotype? Chest 2025;167(3):e103-e104
• Carmona. Bispectral Index Monitoring vs Clinical Assessment for Deep Sedation in the ICU. It’s Not All About the Number. Chest 2025;167(3):e101-e102
  • Carini. Response. Chest 2025;167(3):e102-e103
• Yang. Factors Associated With VTE in Patients Who Are Critically Ill. Chest 2025;167(3):e99
  • Al-Dorzi. Response. Chest 2025;167(3):e99-e101
• Carmona. Volatile sedation for cardiac arrest patients. The question is still unanswered. Resuscitation 2025;epublished March 10th
  • Teiten. Impact of inhaled sedation on delirium incidence and neurological outcome after cardiac arrest – a propensity-matched control study (Isocare) Reply to Carmona et al. (Volatile sedation for cardiac arrest patients. The question is still unanswered). Resuscitation 2025;epublished March 12th

Case Reports

• Messaoudi. Brachiocephalic trunk injuries after central venous catheterization: A case series of surgical management and outcomes. Int J Surg Case Rep 2025;129:111133
• Noguchi. Difficult diagnosis of tetanus in a sedated patient after ileal resection. JA Clin Rep 2025;11:16
• Zambratto. Extracorporeal Membrane Oxygenation in the Treatment of Acute Elemental Mercury Inhalation Toxicity. Chest 2025;167(3):e71-e74
• Zhou. A 71-Year-Old Man With Gas Accumulation in the Left Atrium. Chest 2025;167(3):e75-e81
• Badar. A 52-Year-Old Woman With Shortness of Breath and Left Lower Back Pain. Chest 2025;167(3):e83-e87
• Quah. A 73-Year-Old Man With Right-Sided Chest Pain and Dyspnea. Chest 2025;167(3):e89-e93

Thursday 13th

Narrative Reviews

Clinical

• Wojtaszek. Heart Failure—Focus on Kidney Replacement Therapy: Why, When, and How? Int J Mol Sci 2025;26:2456
• Arora. Disorders of Volume: Core Curriculum 2025. Am J Kidney Dis 2024;epublished December 26th
• Bonner. Renal Tubular Acidosis: Core Curriculum 2025. Am J Kidney Dis 2025;epublished January 23rd
• Teixeira. Continuous Kidney Replacement Therapies: Core Curriculum 2025. Am J Kidney Dis 2025;epublished March 9th
• Schaap. Ultra-Restrictive Transfusion Thresholds in Critically Ill Adults: Are We Ready for the Next Step? Transfus Med Rev 2025;39(2):150893
• Dres. Advancements in imaging techniques for monitoring the respiratory muscles. Crit Care 2025;29:110
• Yang. The promise of transcranial focused ultrasound in disorders of consciousness: a narrative review. Crit Care 2025;29:109

Wednesday 12th

Research

Randomised Controlled Trials

• Spence. Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium: A Cluster Randomized Crossover Trial. JAMA Surg 2025;160(3):286-294
• Park. Safety and Efficacy of Tranexamic Acid in General Surgery. JAMA Surg 2025;160(3):267-274
• Nielsen. Lower or Higher Oxygenation Targets in Patients With COVID-19 in the ICU: A Secondary Bayesian Analysis of the Handling Oxygenation Targets in COVID-19 Trial. Chest 2025;167(3):757-767
• Smit-Fun. Routine anaesthesia ward-based patient visits in surgery: 1-year outcomes of the TRACE randomized clinical trial. Br J Surg 2025;112(3):znaf019

Systematic Reviews & Meta Analyses

• Zhang. Comparison of different treatments of out-of-hospital cardiac arrest: A systematic review and network meta-analysis. Medicine 2025;104(10):e41698

Tuesday 11th

Research

Randomised Controlled Trials

• Bai. Efficacy and safety of gastrodin in preventing postoperative delirium following cardiac surgery: a randomized placebo controlled clinical trial. Crit Care 2025;29:108
• Gannon. Low- vs. Moderate-Intensity Anticoagulation for Venovenous Extracorporeal Membrane Oxygenation: The SAFE-ECMO Pilot Trial. Chest 2025;epublished March 11th
• Cusack. Microcirculation properties of 20 % albumin in sepsis; a randomised controlled trial. J Crit Care 2025;87:155039

Systematic Reviews & Meta Analyses

• Kitisin. Systematic review and meta-analysis of the treatment of hypernatremia in adult hospitalized patients: impact on mortality, morbidity, and treatment-related side effects. J Crit Care 2025;87:155012

Observational Studies

• Eastwood. Magnetic resonance imaging in comatose adults resuscitated after out-of-hospital cardiac arrest: A posthoc study of the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest trial. Aust Crit Care 2025;38(2):101130
• Wittholz. Six-month outcomes after traumatic brain injury in the Augmented versus Routine Approach to Giving Energy multicentre, double-blind, randomised controlled Trial (TARGET). Aust Crit Care 2025;38(2):101116
• Zucman. Water treatment-free prolonged intermittent kidney replacement therapy: A new approach for kidney replacement therapy in the ICU setting. A retrospective study. J Crit Care 2025;87:155014

Guidelines & Position Statements

• Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults An American College of Chest Physicians Clinical Practice Guideline. Chest 2025;epublished March 10th

Monday 10th

Narrative Reviews

Clinical

• Scarlatescu. Disseminated intravascular coagulation and cirrhotic coagulopathy: overlap and differences. The current state of knowledge. Communication from the SSC of the ISTH. J Thromb Haemost 2025;23(3):1085-1106
• Szentgyorgyi. Sedation management and processed EEG-based solutions during venovenous extracorporeal membrane oxygenation: a narrative review of key challenges and potential benefits. J Artif Organs 2025;epublished March 8th
• Uchmanowicz. State of the Art in Measuring Frailty in Patients With Heart Failure: from Diagnosis to Advanced Heart Failure. Curr Heart Fail Rep 2025;22:11
• Davidson. Pulmonary embolism prophylaxis and treatment: What's right, what's wrong, and the future. Chin Med J Pulm Crit Care Med 2025;epublished March 10th
• Carvey. The Management of Severe Sepsis and Septic Shock: A Novel Update and Bedside Reference Guide. Curr Emerg Hosp Med Rep 2025;13:7
• Gardner. Carbapenem de-escalation as an antimicrobial stewardship strategy: a narrative review. JAC Antimicrob Resist 2025;7(2):dlaf022

Editorials

• Koulenti. Antibiotic dosing optimization in critically ill patients. Intensive Care Med 2025;epublished March 10th

Sunday 9th

Research

Randomised Controlled Trials

• Ghadimi. Effects of vitamin D3 supplementation on the recovery of hospitalized burn patients: a randomized double-blind controlled trial. BMC Nutr 2025;11:37

Systematic Reviews & Meta Analyses

• Zhao. Haloperidol for the treatment of delirium in ICU patients: a systematic review and meta-analysis. Eur J Med Res 2025;30:147
• Bharwani. Conservative versus liberal fluid resuscitation for septic patients at risk for fluid overload: A systematic review with meta-analysis. J Crit Care 2025;87:155045
• Liu. The Effectiveness of Target Temperature Management on Poor-Grade Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis. Ther Hypothermia Temp Manag 2025;15(1):1-9

Observational Studies

• Martin-Loeches. End-of-life decision disparities according to the gross national income in critically ill patients: a secondary analysis of the ETHICUS-2 study. Ann Intensive Care 2025;15:29
• Michel-Behnke. Landiolol is effective and safe in paediatric supraventricular tachycardia: evidence from a European prospective multicentre open-label phase III study (LANDI-PED). Europace 2025;27(2):euaf025
• Heijkoop. Preferences for thromboprophylaxis in the intensive care unit: An international survey. Acta Anaesthesiol Scand 2025;69(4):e70009
• Baudry. Prognosis of refractory cardiogenic shock in de-novo versus acute-on-chronic heart failure: Insights from the HYPO-ECMO trial. J Crit Care 2025;87:155043
• Yu. Machine learning models compared with current clinical indices to predict the outcome of high flow nasal cannula therapy in acute hypoxemic respiratory failure. Crit Care 2025;29:101
• Seldén. Net albumin leakage in patients in the ICU with suspected sepsis: A prospective analysis using mass balance calculations. Crit Care 2025;29:106
• Sterr. Being an observer of one’s own life—a meta-synthesis on the experience of mechanically ventilated patients in intensive care units. Crit Care 2025;29:105

Protocols & Statistical Analysis Plans

• Raman. Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): The RESPOND Randomized Controlled Trial Protocol. Pediatr Crit Care Med 2025;26(3):e374-e385

Guidelines & Position Statements

• International Consensus on Evidence Gaps and Research Opportunities in Extracorporeal Cardiopulmonary Resuscitation for Refractory Out-of-Hospital Cardiac Arrest: A Report From the National Heart, Lung, and Blood Institute Workshop. J Am Heart Assoc 2025;epublished online
• Martindale. Parenteral nutritional support in surgical patients: expert consensus statements regarding intravenous lipid emulsions containing omega-3 fatty acids. Front Nutr 2025;12:1546089
• Clinical management and therapeutic optimization of patients with heart failure with reduced ejection fraction and low blood pressure: A clinical consensus statement of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 2025;epublished February 26th
• Guidelines for the Echocardiographic Assessment of the Right Heart in Adults and Special Considerations in Pulmonary Hypertension: Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr 2025;38(3):141-186

Narrative Reviews

Clinical

• MacIntyre. Managing mechanical ventilation: Clinical challenges 2024. J Precision Respiratory Medicine 2025;8(1):26-32
• Hawatian. Contemporary Approach to Acute Pancreatitis in Emergency Medicine. JAECEP Open 2025;6(2):100063
• Haider. From Critical Care to Transplant: Enhancing Outcomes in Acute-on-Chronic Liver Failure. Curr Hepatology Rep 2025;24:9
• Yang. Advances in the diagnosis of early biomarkers for acute kidney injury: a literature review. BMC Nephrol 2025;26:115
• Kholmukhamedov. Anticoagulation Management: Current Landscape and Future Trends. J Clin Med 2025;14(5):1647
• Jung. Anticoagulation in venovenous extracorporeal membrane oxygenation. Front Med 2025;12:1530411
• Niroomand. Current challenges in lung transplantation. J Intern Med 2025;epublished March 5th
• Edwardson. Withdrawal of life-sustaining therapies for awake patients in critical care: The benefits of a collaborative intensivist & palliative care approach. J Intensive Care Soc 2025;epublished March 4th
• Peng. Progress on diagnosis and treatment of multisystem inflammatory syndrome in children. Front Immunol 2025;16:1551122
• Canbaz. Mechanical Protective Ventilation: New Paradigms in Thoracic Surgery. J Clin Med 2025;14(5):1674
• Putot. Comprehensive management of pneumonia in older patients. Eur J Intern Med 2025;epublished February 27th
• Jesus. Diaphragm dysfunction: how to diagnose and how to treat? Breathe 2025;21(1):240218
• Möller. The Perception of the Diaphragm with Ultrasound: Always There Yet Overlooked? Life 2025;15(2):239
• ELMeneza. Review of Precision Medicine and Diagnosis of Neonatal Illness. Diagnostics 2025;15:478
• Khandait. Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances. Cardiorenal Med 2025;15(1):41–60
• Ingen-Housz-Oro. Diagnosing and Managing Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Adults: Review of Evidence 2017–2023. J Invest Derm 2025;epublished February 27th
• Dabetic. Advances in Managing Pelvic Fractures in Polytrauma: A Comprehensive Review. J Clin Med 2025;14:1492
• Ganti. Management of acute ischemic stroke in the emergency department: optimizing the brain. Int J Emerg Med 2025;18:7
• Sookdeo. Current understanding of stroke and stroke mimics in adolescents and young adults: a narrative review. Int J Emerg Med 2024;17:180
• Lao-amornphunkul. Assessment of sleep quality in the Intensive Care Unit: A comprehensive review of tools and techniques. Clin Crit Care 2025;33(1):e250004
• Deguise. NIPPV vs CPAP: Lessons from meta-analyses. Sem Perinatol 2025;epublished March 6th
• Hu. Artificial intelligence and pediatric acute kidney injury: a mini-review and white paper. Front Nephrol 2025;5:1548776
• Balali-Mood. Recent advances in the clinical management of intoxication by five heavy metals: Mercury, lead, chromium, cadmium and arsenic. Heliyon 2025;11(4):e42696
• de Mattos. Which patients benefit the most? An update on transjugular intrahepatic portosystemic shunt. World J Hepatol 2025;17(2):99809
• Kushima. Cryptococcosis. Med Mycol J 2025;66(1):27-31

Editorials

• Kalil. Subphenotypes and phenotypes to resolve sepsis heterogeneity: hype or hope?. Intensive Care Med 2025;epublished March 6th
• Tachibana. Cardiogenic Shock: A Cardiac Anesthesiologist perspective on an ever-evolving clinical challenge. J Cardiothorac Vasc Anesth 2025;epublished March 4th

Commentaries

• Zimmermann. The Search for Sepsis Biomarkers: A Tale of Promises, Pitfalls, and Potential. Crit Care Med 2025;53(3):e543-e547
• Samprathi. Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be used in Children with Septic Shock? No. Indian Pediatr 2025;epublished online
• McNeilly. Prehospital Blood Administration in Traumatic Hemorrhagic Shock. JACEP Open 2025;6(2):100041
• Shamavu. Rethinking Pediatric Sepsis and Septic Shock: Beyond International Consensus Criteria. Pediatr Health Med Ther 2025;16:61–65
• Yancy. Heart Failure: A Century View, From Failure to Function. Circulation 2025;epublished March 3rd

Correspondence

• Khan. The Next Pandemic? Streptococcal Toxic Shock Syndrome on the Rise. Disaster Med Public Health Prep 2025;19:e53
• Liao. Further considerations on the clinical applicability of time to positivity as a prognostic tool for catheter-related Pseudomonas aeruginosa bloodstream infections. Crit Care 2025;29:94
• Feng. Predicting Contrast-Associated Acute Kidney Injury. JAMA Netw Open 2025;8(3):e250107
• Lightburn. Suture choice when securing central lines: an update in the light of NICE surgical guidance. Anaesthesia 2025;epublished February 27th
• Various. Mechanical circulatory support for cardiogenic shock. Lancet 2025;405(10480):696-700
  • Liu  |  Dalzell  |  Wang  |  Zhang  |  Giacardi
  • Thiele – Authors' reply

Case Reports

• Costa. An Under-Recognised Rapidly Fatal Condition: Phlegmonous Gastritis. Eur J Case Rep Intern Med 2025;12(3):005175
• Geerdink. Sodium azide (NaN3) intoxication, “the man who lived”: potential effective antidote and treatment strategy. Crit Care 2025;29:103
• Sun. Electrical impedance tomography-guided the optimal awake prone position in a moderate ARDS patient. Crit Care 2025;29:95
• Arbaugh. Management of a traumatic splenic injury in the setting of polysubstance use and challenging social factors. Trauma Surg Acute Care Open 2025;10:e001680
• Saldana. Not All Heart Failure Improves With Diuresis: A Lesson in Left Ventricular Assist Device Physiology. CASE 2025;epublished March 6th
• Thanapongsatorn. Simultaneous extracorporeal liver and cardiorespiratory support with double plasma molecular absorption system and extracorporeal membrane oxygenation: A case report. Clin Crit Care 2025;33(1):e250006
• Tavornshevin. Bilateral spontaneous pneumothorax in undiagnosed asthma in an adult: Bilateral spontaneous pneumothorax in acute asthma attack. Clin Crit Care 2025;33(1):e250001
• Benser. Many Roads Traveled: Sonographer Insights on Clots in Transit—An Echocardiography Case Series. CASE 2025;epublished March 8th
• Shin. Cardiac Tamponade in Pulmonary Hypertension: Management Using Right Heart Catheterization Guidance. J Cardiothorac Vasc Anesth 2025;epublished March 7th
• Schmidt. A Case Series Study of Airway Pressure Release Ventilation in Patients with Intracranial Pathologies and Acute Respiratory Failure. J Intensive Care Med 2025;epublished February 27th

Saturday 8th

Research

Randomised Controlled Trials

• Cotton. Effect of Monetary Incentives on Peer Review Acceptance and Completion: A Quasi-Randomized Interventional Trial. Crit Care Med 2025;epublished March 6th

Systematic Reviews & Meta Analyses

• Panda. Role of therapeutic plasma exchange on survival in pediatric acute liver failure and acute-on chronic liver failure: A systematic review and meta-analysis. Indian J Gastroenterol 2025;epublished March 4th
• Suntornlekha. Benefit of inodilators in septic shock patients: A systematic review and network meta-analysis : Inodilators in septic shock: Network meta-analysis. Clin Crit Care 2025;33(1):e250007
• Chen. Efficacy and safety of prone positioning in patients undergoing extracorporeal membrane oxygenation (ECMO): A systematic review and meta-analysis. J Clin Anesth 2025;103:111786

Observational Studies

• Patidar. Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study. Lancet Gastroenterology & Hepatology 2025;epublished March 6th
• Leligdowicz. Decoding Sepsis Globally: Toward Precision Medicine through Clustering in Sub-Saharan Africa. Am J Respir Crit Care Med 2025;211(3):307–309
• Jeong. Time to Renal Replacement Therapy Initiation in Critically Ill Patients With Acute Kidney Injury: A Secondary Analysis of the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial. Crit Care Med 2025;epublished March 3rd
• Cama-Olivares. Association of Hepatorenal Syndrome-Acute Kidney Injury with Mortality in Patients with Cirrhosis Requiring Renal Replacement Therapy: Results from the HRS-HARMONY Consortium. Kidney360 2025;6(2):247–256
• Chen PH. Efficacy and safety of prone positioning in patients undergoing extracorporeal membrane oxygenation (ECMO): A systematic review and meta-analysis. J Clin Anesth 2025;103:111786
• Morris. Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS). Am J Respir Crit Care Med 2025;epublished March 5th

Friday 7th

Narrative Reviews

Clinical

• Robert. Managing Refractory Hypoxemia in Acute Respiratory Distress Syndrome Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review. J Clin Med 2025;14(5): 1653
• Dettling. Antiplatelet therapy in acute myocardial infarction complicated by cardiogenic shock. Clin Res Cardiol 2025;epublished March 4th
• Ma. Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies. Signal Transduct Target Ther 2025;10(1):75
• Chanchlani. Extracorporeal pediatric renal replacement therapy: diversifying application beyond kidney failure. Pediatr Nephrol 2025;40(4):923-932
• Idasiak-Piechocka. Effect of hypoalbuminemia on drug pharmacokinetics. Front Pharmacol 2025;16:1546465

Thursday 6th

Narrative Reviews

Clinical

• Patschan. Recovery of kidney function in acute kidney injury. J Nephrol 2025;epublished March 1st
• Smith. Artificial Intelligence in Emergency Medicine: A Primer for the Nonexpert. JACEP Open 2025;6(2):100051
• Alverdy. Unpacking the sepsis controversy: Trauma Surg Acute Care Open 2025;10:e001733
• de Mattos. Which patients benefit the most? An update on transjugular intrahepatic portosystemic shunt. World J Hepatol 2025;17(2):99809

Wednesday 5th

Narrative Reviews

Clinical

• Paternoster. Awake veno-venous extracorporeal membrane oxygenation: practical aspects and considerations. Minerva Anestesiol 2025;91(1-2):92-100
• Tiwari. Insights into medication-induced liver injury: Understanding and management strategies. Toxicol Rep 2025;14:101976
• Haudebourg. Noninvasive ventilation in acute hypoxemic respiratory failure: What is the future? J Intensive Med 2025;epublished March 4th
• Morris. Causes and management of impaired gas exchange in critically ill patients. BJA Education 2025;25:90-98

Tuesday 4th

Research

Randomised Controlled Trials

• Butler. Randomized Clinical Trial of the Four Supports Intervention for Surrogate Decision-Makers in Intensive Care Units. Am J Respir Crit Care Med 2025;211(3):370-380
  
  • Editorial:  Courtright. The Struggle Continues: Improving Outcomes for Surrogate Decision-Makers after the ICU. Am J Respir Crit Care Med 2025;211(3):309–311

Observational Studies

• Jubran. Air Hunger Far Exceeds Dyspnea Sense of Effort during Mechanical Ventilation and a Weaning Trial. Am J Respir Crit Care Med 2025;211(3):323–330
  
  • Editorial:  Banzett. Target for Today: Air Hunger. Am J Respir Crit Care Med 2025;211(3):300–301
• van Amstel. Temporal Transitions of the Hyperinflammatory and Hypoinflammatory Phenotypes in Critical Illness. Am J Respir Crit Care Med 2025;211(3):347–356
  
  • Editorial:  Ceccato. Dynamics of Subphenotypes in Critical Illness: When the Tick-Tock of the Clock Counts. Am J Respir Crit Care Med 2025;211(3):305–307
• Cummings. Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa. Am J Respir Crit Care Med 2025;211(3):357–369
  
  • Editorial:  Leligdowicz. Decoding Sepsis Globally: Toward Precision Medicine through Clustering in Sub-Saharan Africa. Am J Respir Crit Care Med 2025;211(3):307–309

Narrative Reviews

Clinical

• Pearce. Pleural Infection: Diagnosis, Management, and Future Directions. J Clin Med 2025;14(5):1685
• Feng. Sepsis: the evolution of molecular pathogenesis concepts and clinical management. MedComm 2025;6(3):e70109
• Ham. Targeted nutritional strategies in postoperative care. Anesth Pain Med 2025;20(1):34–45
• Yessayan. Extracorporeal therapies in sepsis: a comprehensive review of the Selective Cytopheretic Device, Polymyxin B and Seraph cartridges. Renal Fail 2025;47(1):2459349
• Joachim. Resuscitative Thoracotomy in Children: Indications, Technical Aspects, and Impact on the Care Team. Curr Trauma Rep 2-025;11:9
• Remondelli. Advancements in Prehospital, En-Route, and Damage Control Casualty Care and Areas of Future Research for Large-Scale Combat Operations. Curr Trauma Rep 2025;11:7

Monday 3rd

Narrative Reviews

Clinical

• Huang. Understanding hemodynamic incoherence: mechanisms, phenotypes, and implications for treatment. Shock 2025;63(3):342-350
• Hickson. Emerging antimicrobial therapies for Gram-negative infections in human clinical use. NPJ Antimicrob Resist 2025;3:16
• Kataria. Redefining haemostasis: Role of rotational thromboelastometry in critical care settings. World J Crit Care Med 2025;14(2):102521
• Beij. Acute Pancreatitis: An Update of Evidence‐Based Management and Recent Trends in Treatment Strategies. United European Gastroenterol J 2025;13(1):97–106
• Silva. Strategic Use of Intravenous Medications to Protect Target Organs in Hypertensive Emergencies. Int J Cardiovasc Sci 2025;38
• Dharmakumar. Reperfused Myocardial Infarction: The Road to CCS Classification of Acute MI and Beyond. JACC Adv 2025;4(2):101528

Sunday 2nd

Narrative Reviews

Clinical

• Omidi. What is new in altitude- and cold-related illnesses of travel: appraisal and summary of the updated guidelines from the Wilderness Medical Society. Int J Environ Res Public Health 2025;22:284
• Möller. The perception of the diaphragm with ultrasound: always there yet overlooked? Life 2025;15(2):239
• Alberti. Respiratory support strategies for surgical neonates: a review. Children 2025;12:273
• Vidal-Cortés. Difficult-to-treat Pseudomonas aeruginosa infections in critically ill patients: a comprehensive review and treatment proposal. Antibiotics 2025;14:178
• Kumar Krishnegowda. Neonatal shock: current dilemmas and future research avenues. Children 2025;12:128
• Catalani. Left ventricular thrombosis in ischemic and non-ischemic cardiomyopathies: focus on evidence-based treatment. J Clin Med 2025;14(5):1615
• Hashimoto. Current progress in peritoneal dialysis: a narrative review of progress in peritoneal dialysis fluid. Life 2025;15(2):279
• Lazarou. Non-invasive biomarkers for early diagnosis of kidney allograft dysfunction: current and future applications in the era of precision medicine. Medicina 2025;61(2):262
• Cuttone. Exploring the utility of renal resistive index in critical care: insights into ARDS and cardiac failure. Biomedicines 2025;13(2):519
• Wilk. Use of artificial intelligence in difficult airway assessment: the current state of knowledge. J Clin Med 2025;14(5):1602
• Oprita. Management of severe hypothermia: challenges and advanced strategies. J Clin Med 2025;14(5):1584
• Filipska-Blejder. Efficacy and safety of early mobilization and factors associated with rehabilitation after stroke—a review. J Clin Med 2025;14(5):1585
• Virzì. Neutrophil gelatinase-associated lipocalin: biological aspects and potential diagnostic use in acute kidney injury. J Clin Med 2025;14(5):1570
• Li. Underlying mechanisms and treatment of acetaminophen‑induced liver injury. Mol Med Rep 2025;31(4):106
• Sepúlveda. Protocolized strategies to encourage early mobilization of critical care patients: challenges and success. Crit Care Sci 2025;37:e20250128
• Kumar. Sepsis in liver failure patients: diagnostic challenges and recent advancements. World J Crit Care Med 2025;14(2):101587
• Nedel. Why should lymphocytes immune profile matter in sepsis? World J Crit Care Med 2025;14(2):98791
• Wang. Evaluation of vitamin D supplementation in critically ill patients—a narrative review of randomized controlled trials published in the last 5 years. Nutrients 2025;17:816
• Dutta. Anesthetic considerations for robotic liver transplantation. J Cardiothorac Vasc Anesth 2025;epublished February 27th
• Cecconi. Unlocking opportunities to transform patient care: an expert insight on limitations and opportunities in patient monitoring. ICMx 2025;13:24
• Khin. Imaging of congestion in cardio-renal syndrome. Curr Heart Fail Rep 2025;22(1):10
• Choi. Heterogeneity in meta-analyses: an unavoidable challenge worth exploring. Kor J Anesth 2025;epublished February 14th
• Nakhaie. Mpox and viral co-infections: a narrative review. Health Sci Rep 2025;8(2):e70464

Commentaries

• Tracy. The case for an international severity of illness scoring system. Crit Care Sci 2025;37:e20250293
• Teixeira. The quandary of anticoagulation for sepsis patients with new-onset atrial fibrillation. Crit Care Sci 2025;37:e20250120
• Moralez. How to use intensive care unit scoring systems: a practical guide for the intensivist. Crit Care Sci 2025;37:e20250347
• Yaxley. Care of the chronic dialysis patient in the intensive care unit: a state-of-the-art review. Crit Care Sci 2025;37:e20250130
• Sepúlveda. Protocolized strategies to encourage early mobilization of critical care patients: challenges and success. Crit Care Sci 2025;37:e20250128
• Kreymann. Nutrition therapy for critically ill patients - five key problems. Clin Nutr 2025;46:45-51

Correspondence

• Catozzi. Analyzing PaO₂/FiO₂? Mind the interaction with PEEP! Authors’ reply. Intensive Care Med 2025;epublished February 24th
• Thomas. The MRC CRASH trial at 20: time to reappraise corticosteroids for traumatic brain injury? J Intensive Care Soc 2025;epublished February 22nd
• Wu. Efficacy and safety of high protein intake in critically ill patients. Chin Med J 2025;epublished February 26th
• Jayaprakash. Sepsis resuscitation: caution against conflating initial fluid resuscitation and overall sepsis management. JACEP Open 2025;6(2):100080
• Shot in the thigh or stab in the dark? Challenging the evidence for IM adrenaline in OHCA. Resuscitation 2025;epublished January 24th

Case Reports

• Pearcey. Acute intermittent hypoxia in people living with chronic stroke: a case series. Stroke 2025;epublished February 25th
• Wang. Paroxysmal sympathetic hyperactivity and refractory hypotension in Guillain-Barré syndrome with autoimmune encephalitis: a case report and literature review. Front Neurosci 2025;19:1534771
• Patil. Complications of pulmonary embolism in a pediatric patient. JACC Case Rep 2025;30(3):103221
• Volpon. Caffeine-clarithromycin coadministration and hyperlactatemia in a young infant: a case report. Crit Care Sci 2025;37:e20250159

Saturday 1st

Research

Randomised Controlled Trials

• Cusack. Microcirculation properties of 20% albumin in sepsis; a randomised controlled trial. J Crit Care 2025;87:155039
• Dargent. Dexmedetomidine to Reduce Vasopressor Resistance in Refractory Septic Shock: α2 Agonist Dexmedetomidine for REfractory Septic Shock (ADRESS): A Double-Blind Randomized Controlled Pilot Trial. Crit Care Med 2025;epublished February 28
• Muraleedharan. Effect of platelet storage duration on platelet increment and clinical outcomes in critically ill patients - A randomised controlled trial. Transfus Clin Biol 2025;32(1):20-27
• Bradbury. Plain versus drug balloon and stenting in severe ischaemia of the leg (BASIL-3): open label, three arm, randomised, multicentre, phase 3 trial. BMJ 2025;388:e080881

Systematic Reviews & Meta Analyses

• Ye. Preoxygenation strategies before intubation in patients with acute hypoxic respiratory failure: a network meta-analysis. Front Med (Lausanne) 2025;12:1532911
• Günkan. Thrombolysis for ischemic stroke beyond the 4.5-hour window: a meta-analysis of randomized clinical trials. Stroke 2025;56(3)
• Xu. Application of norepinephrine in the treatment of septic shock: a meta-analysis. Ir J Med Sci 2024;194(1):361–369
• McChesney. Impact of short-acting beta-blockers on the outcomes of patients with septic shock: a systematic review and meta-analysis. Crit Care Med 2025;epublished February 26th
• Sanchez-Piedra. Electrical impedance tomography for PEEP titration in ARDS patients: a systematic review and meta-analysis. J Clin Monit Comput 2025;epublished February 26th
• Alkhuzaee. Acetazolamide for the management of diuretic-induced chloride depletion alkalosis: a systematic review. J Clin Med 2025;14(4):1041
• Li. The effect of early rehabilitation on therapeutic outcomes in ICU patients on mechanical ventilation: a meta-analysis. Int J Artif Organs 2025;48(2):105-122
• Rapszky. Rapid molecular assays versus blood culture for bloodstream infections: a systematic review and meta-analysis. eClinicalMedicine 2025;79:103028
• Bauer. Adjunctive vasopressors and short-term mortality in adults with septic shock: a systematic review and meta-analysis. Shock 2025;epublished February 7th

Observational Studies

• Angriman. Timing of extubation in adult patients with acute brain injury. Am J Respir Crit Care Med 2025;211(3):339-346
• Barbier. Prognostic impact of early appropriate antimicrobial therapy in critically ill patients with nosocomial pneumonia due to Gram-negative pathogens: a multicenter cohort study. Crit Care Med 2025;epublished February 26th
• Yvin. Escalation of oxygenation modalities and mortality in critically ill immunocompromised patients with acute hypoxemic respiratory failure: a clustering analysis of a prospectively multicenter, multinational dataset. Crit Care Med 2025;epublished February 27th
• Henríquez-Beltrán. The trajectory of sleep after critical illness: a 24-month follow-up study. Ann Intensive Care 2025;15(1):28
• O’Keefe. Time to bystander CPR and survival for witnessed out-of-hospital cardiac arrest. Resuscitation 2025;epublished February 25th
• Buckley. ICU patient-to-pharmacist ratios: a prospective, multicenter time-motion study. Crit Care Med 2025;epublished February 26th
• Zalucky. Elastance may determine the neuromuscular blockade effect on mortality in acute respiratory distress syndrome. Am J Respir Crit Care Med 2025;epublished February 25th
• Perkins. Prehospital resuscitative thoracotomy for traumatic cardiac arrest. JAMA Surg 2025;epublished February 26th

Guidelines & Position Statements

• Taneri. Proposed Core Outcomes After Neonatal Sepsis. A Consensus Statement. JAMA Netw Open 2025;8(2):e2461554

Editorials

• Ostermann. Hemoadsorption in septic shock – PRO. Intensive Care Med 2025;epublished February 24th
• Gigax. Rescue spinal drain after high-risk TEVAR is a patient safety issue for anesthesiologists: the need for institutionalized protocols. J Cardiothorac Vasc Anesth 2025;epublished February 26th
• Dodge. The VANISH2 trial and its implications for cardiac anesthesiologists. J Cardiothorac Vasc Anesth 2025;epublished February 24th
• Tempe. The conundrum of perioperative management of patients with diastolic dysfunction undergoing cardiac surgery. J Cardiothorac Vasc Anesth 2025;epublished February 22nd
• Kawano-Dourado. Best practices for guideline development in critical care. Crit Care Sci 2025;37:e20250372
• Bugedo. Thank you, Professor Gattinoni†, and have a good trip to eternity! Crit Care Sci 2025;37:e20250002
• Veiga. Ventriculostomy-associated infections: a healthcare issue in the neurointensive care unit. Crit Care Sci 2025;37:e20250250ed
• Roepke. Scientific output and intensive care units organizational characteristics: a tale of unintended consequences. Crit Care Sci 2025;37:e20250305
• Moreno. Intensive care medicine in Portugal. Crit Care Sci 2025;37:e20250344
• Msilanga. Classifying severe acute kidney injury in cirrhosis: implications for mortality? Kidney360 2025;6(2):182-184
• Su. Molecular biomarkers and more efficient therapies for sepsis. Biomedicines 2025;13(2):468
• Hassanein. Global hemodialysis vascular access care: three decades of evolution. J Vasc Access 2025;26(1):5-14

Friday 28th

Guidelines & Position Statements

• 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2025;epublished February 27th

Research

Observational Studies

• The African Critical Illness Outcomes Study (ACIOS) Investigators. The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa. Lancet 2025;405(10480):715-724

Narrative Reviews

Clinical

• Angelucci. Wearable devices for patient monitoring in the intensive care unit. ICMx 2025;13:26

Thursday 27th

Narrative Reviews

Clinical

• Alsabri. Diabetic Ketoacidosis in Pediatric Emergency Medicine: Risk Factors, Myths, and Evidence-Based Management of Complications. Curr Emerg Hosp Med Rep 2025;13:6
• Deshwal. Patient-Self Inflicted Lung Injury (P-SILI): An Insight into the Pathophysiology of Lung Injury and Management. J Clin Med 2025;14:1632
• Francovich. Electrical impedance tomography to set positive end-expiratory pressure. Curr Opin Crit Care 2025;epublished February 13th
• Sandarage. Time is spine: critical updates for the intensivist. Curr Opin Crit Care 2025;epublished February 27th

Guidelines & Position Statements

• Extracorporeal Life Support Organization 2024 Guideline for Early Rehabilitation or Mobilization of Adult Patients on Extracorporeal Membrane Oxygenation. ASAIO J 2025;71(3):187-199
• Update of guidelines for management of community acquired pneumonia in adults by the French infectious disease society (SPILF) and the French-speaking society of respiratory diseases (SPLF). Endorsed by the French intensive care society (SRLF), the French microbiology society (SFM), the French radiology society (SFR) and the French emergency society (SFMU). Infect Dis Now 2025;epublished February 25th
• Liu. Guidelines for the use of lung ultrasound to optimise the management of neonatal respiratory distress: international expert consensus. BMC Med 2025;23:114

Wednesday 26th

Narrative Review

Clinical

• Soranno. A review of gut failure as a cause and consequence of critical illness. Crit Care 2025;29:91

Research

Randomised Controlled Trials

• Fernandez-Bustamante. Perioperative lung expansion and pulmonary outcomes after open abdominal surgery versus usual care in the USA (PRIME-AIR): a multicentre, randomised, controlled, phase 3 trial. Lancet Respir Med 2025;epublished February 25th
  • Commentary: Blank. Perioperative lung expansion and pulmonary outcomes after abdominal surgery. Lancet Respir Med 2025;epublished February 25th
• Porter. Discussing expected long-term quality of life in the ICU: effect on experiences and outcomes of patients, family, and clinicians—a randomized clinical trial. Intensive Care Med 2025;epublished February 24th

Systematic Reviews & Meta Analyses

• Chandelia. Balanced Salt Solution Versus Normal Saline as Resuscitation Fluid in Pediatric Septic Shock: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Intensive Care Med 2025;epublished February 23rd

Observational Studies

• De Piero. In-hospital outcomes and 6-month follow-up results of patients supported with extracorporeal membrane oxygenation for COVID-19 from the second wave to the end of the pandemic (EuroECMO-COVID): a prospective, international, multicentre, observational study. Lancet Respir Med 2025;epublished February 25th
  • Commentary:  Hayanga. Long-term outcomes and the future of extracorporeal care. Lancet Respir Med 2025;epublished February 25th
• Robba. Ventilation practices in acute brain injured patients and association with outcomes: the VENTIBRAIN multicenter observational study. Intensive Care Med 2025;epublished February 24th
• Stadlbauer. Management of high-risk acute pulmonary embolism: an emulated target trial analysis. Intensive Care Med 2025;epublished February 25th

Tuesday 25th

Guidelines & Position Statements

• The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024. Acute Med Surg 2025;12(1):e70037

Narrative Reviews

Clinical

• Al-Husinat. A narrative review on the future of ARDS: evolving definitions, pathophysiology, and tailored management. Crit Care 2025;29:88
• Leon. The Role of Selected Adjuncts in the Management of the Bleeding Trauma Patient: Calcium and Vasopressin. Curr Anesthesiol Rep 2025;15:32

Monday 24th

Narrative Reviews

Clinical

• Hrymak. ECMO for the pregnant and peripartum patient: A practical review of indications, unique management considerations, and an approach framework. Perfusion 2025;epublished February 23rd
• Fosse. Can intubate, cannot ventilate: A proposed algorithm to handle problems with ventilation and oxygenation after intubation. Acta Anaesthesiol Scand 2025;69(3):e70007
• Batarda Sena. Evidence-Based Approach to Cerebral Vasospasm and Delayed Cerebral Ischemia: Milrinone as a Therapeutic Option—A Narrative Literature Review and Algorithm Treatment Proposition. Neurol Int 2025;17:32
• Michard. AI for the hemodynamic assessment of critically ill and surgical patients: focus on clinical applications. Ann Intensive Care 2025;15:26 

Pediatric Critical Care Medicine Series on Phoenix Sepsis Definition

• Watson. The 2024 Phoenix Sepsis Score Criteria: Part 1, the Evolution in Definition of Sepsis and Septic Shock. Pediatr Crit Care Med 2025;26(2):e246-e251
• de Oliveira. The 2024 Phoenix Sepsis Score Criteria: Part 2, What About Using Interventions in the Criteria? Pediatr Crit Care Med 2025;26(2):e252-e255
• Hall. The 2024 Phoenix Sepsis Score Criteria: Part 3, What About Using Stages of Sepsis in the Criteria? Pediatr Crit Care Med 2025;26(2):e256-e261
• Wiens. The 2024 Phoenix Sepsis Score Criteria: Part 4, What About Using World-Oriented Criteria? Pediatr Crit Care Med 2025;26(2):e262-e265
• Randolph. The 2024 Phoenix Sepsis Score Criteria: Part 5, What About “Parsimony” in the Criteria—Is Less Really More? Pediatr Crit Care Med 2025;26(2):e266-e271
  • Editorial:  Tasker. What Do We Know About Pediatric Sepsis Scoring Post-Phoenix? Pediatr Crit Care Med 2025;26(2):e237-e240
  • Commentary:  Polikoff. Phoenix Rising: External Validation of the Phoenix Sepsis Criteria. Pediatr Crit Care Med 2025;26(2):e241-e243

Sunday 23rd

Research

Randomised Controlled Trials

• Li. Cerebral oxygenation and hemodynamic changes during ephedrine and phenylephrine administration for transient intraoperative hypotension in patients undergoing major abdominal surgery: a randomized controlled trial. BMC Anesthesiol 2025;25(1):87
• Gupta. Comparative Study of Terlipressin and Noradrenaline as Vasopressors in Patients With Acute-on-chronic Liver Failure and Septic Shock: A Randomized Controlled Trial. J Clin Exp Hepatol 2025;15(3):102494
• Yang. Low versus high peripheral oxygen saturation directed oxygen therapy in critically ill patients: a multicenter randomized controlled trial. MedComm 2025;6(3):e70098
• Almeida. Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock: A Phase 2, Placebo-Controlled, Randomized Clinical Trial. Crit Care Med 2025;53(2):e269-e281
• Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial. Crit Care Med 2025;53(2):e257-e268
• Zhang. Efficacy and safety of esketamine for emergency endotracheal intubation in ICU patients: a double-blind, randomized controlled clinical trial. Sci Rep 2025;15(1):6089
• Takia. Additional Bicarbonate Infusion Complements WHO Rehydration Therapy in Children with Acute Diarrhea and Severe Dehydration Presenting with Severe Non-anion Gap Metabolic Acidemia: An Open Label Randomized Trial. Indian J Pediatr 2025;92(3):268-276
• Rachana. Non-invasive high-frequency oscillatory ventilation versus non-invasive intermittent mandatory ventilation as a rescue mode in preterm infants with respiratory distress on nasal CPAP-a randomized control trial. Eur J Pediatr 2025;184(3):205

Systematic Reviews & Meta Analyses

• Feng. Safety and effectiveness of inhaled sedation in critically ill patients: a systematic review and meta-analysis. Syst Rev 2025;14(1):44
• Benjamin. Impact of early enteral nutrition in critically ill children: A systematic review and meta-analysis. JPEN J Parenter Enteral Nutr 2025;epublished February 19th
• Chen. Electrical impedance tomography-guided positive end-expiratory pressure titration for perioperative oxygenation and postoperative pulmonary complications: A systematic review and meta-analysis. Medicine 2024;103(52):e40357
• Boulton. Benefits of targeted deployment of physician-led interprofessional pre-hospital teams on the care of critically ill and injured patients: a systematic review and meta-analysis. Scand J Trauma Resusc Emerg Med 2025;33(1):33
• Papazisi. Vasoplegia in cardiac surgery: A systematic review and meta-analysis of current definitions and their influence on clinical outcomes. J Cardiothorac Vasc Anesth 2025;epublished February 21st
• Attachaipanich. Timing of mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock: A systematic review and meta-analysis. Am Heart J Plus 2025;50:100506
• Cai. Effect of restrictive fluid resuscitation on severe acute kidney injury in septic shock: a systematic review and meta-analysis. BMJ Open 2025;15:e086367
• The Effect of Severe Sepsis and Septic Shock Management Bundle (SEP-1) Compliance and Implementation on Mortality Among Patients With Sepsis. Ann Intern Med 2025;epublished February 18th

Observational Studies

• Du. Impact of red blood cell transfusion in massive burn: a multicenter cohort study. Sci Rep 2025;15(1):6196
• Pier Paolo Bocchino. Organ perfusion pressure predicts outcomes in cardiogenic shock patients. Eur J Heart Fail 2025;epublished February 16th
• Alamin. Antibiotic allergy de-labeling in the intensive care unit: The prospective ADE-ICU study. J Crit Care 2025;85:154977
• d'Aranda. Discarded intravenous medication in the ICU: the GAME-OVER multicenter prospective observational study. Crit Care 2025;29(1):84
• Belletti. Intravenous amino acids for renal protection in patients receiving temporary mechanical circulatory support: a secondary subgroup analysis of the PROTECTION study. Eur J Cardiothorac Surg 2025;epublished February 20th
• Murphy. Development of a Core Critical Care Data Dictionary With Common Data Elements to Characterize Critical Illness and Injuries Using a Modified Delphi Method. Crit Care Med 2025;epublished February 21st
• Armaignac. Guiding Principles for Data Sharing and Harmonization: Results of a Systematic Review and Modified Delphi From the Society of Critical Care Medicine Data Science Campaign. Crit Care Med 2025;epublished February 21st
• Attachaipanich. Timing of mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock: A systematic review and meta-analysis. Am Heart J Plus 2025;50:100506
• Cheskes. The impact of alternate defibrillation strategies on time in ventricular fibrillation. Resuscitation 2025;epublished February 17th
• van de Munckhof. Direct oral anticoagulants versus vitamin K antagonists for cerebral venous thrombosis (DOAC-CVT): an international, prospective, observational cohort study. Lancet Neurol 2025;24(3):199-207
• Gelbenegger. Lactated Ringer’s or Normal Saline for Initial Fluid Resuscitation in Sepsis-Induced Hypotension. Crit Care Med 2025;epublished February 19th

Guidelines & Position Statements

• Diaz. Evidence-based, cost-effective management of acute appendicitis: An algorithm of the Journal of Trauma and Acute Care Surgery emergency general surgery algorithms work group. J Trauma Acute Care Surg 2025;98(3):368-373
• Appelbaum. Handoffs and transitions of care in the intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open 2025;10(1):e001677

Narrative Reviews

Clinical

• Fadlallah. Update on the Complications and Management of Liver Cirrhosis. Med Sci 2025;13(1):13
• Kotani. Intravenous amino acid for kidney protection: current understanding and future perspectives. Clin Kidney J 2024;18(2):sfae409
• Gürtler. Viral sepsis – pathophysiology and disease manifestation. Infection 2025;epublished February 17th
• L'Huillier. The always evolving diagnosis and management of Clostridioides difficile colitis: What you need to know. J Trauma Acute Care Surg 2025;98(3):357-367
• Wall. Tips and tricks in the operative management of esophageal, trachea, and bronchial injuries: What you need to know. J Trauma Acute Care Surg 2025;98(3):347-356
• Maessen. Viral reactivations and fungal infections in nonresolving acute respiratory distress syndrome. Eur Respir Rev 2025;34(175):240153
• Pène. Thrombocytopenia in the intensive care unit: diagnosis and management. Ann Intensive Care 2025;15:25
• Agosta. Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review. Artif Organs 2025;epublished February 20th
• Marrapu. Transition from acute kidney injury to chronic kidney disease in liver cirrhosis patients: Current perspective. World J Nephrol 2025;14(1):102381
• Campos-Sáenz. VExUS Protocol Along Cardiorenal Syndrome: An Updated Review. J Clin Med 2025;14:1334
• Pederson. Controversies in the Management of Acute Pulmonary Embolism in the Emergency Department. J Emerg Med 2024;epublished October 23rd
• Parlati. Biomarkers for Congestion in Heart Failure: State-of-the-art and Future Directions. Card Fail Rev 2025;11:e01
• Guo. Mechanisms of sepsis-induced acute liver injury: a comprehensive review. Front Cell Infect Microbiol 2025;15:1504223
• Cecconi. Unlocking opportunities to transform patient care: an expert insight on limitations and opportunities in patient monitoring. ICMx 2025;13:24
• Skvarce. Multisystem hemodynamic effects of terlipressin in cirrhosis: A scoping review. J Crit Care 2025;87:155038
• Saito. Sepsis in Global Health: Current global strategies to fight against sepsis. Acute Med Surg 2025;epublished February 19th
• Neri. Transient tachypnoea: new concepts on the commonest neonatal respiratory disorder. Eur Respir Rev 2025;34(175):240112
• Gyawali. Biologics in severe asthma: a state-of-the-art review. Eur Respir Rev 2025;34(175):240088
• Ako. Electrical impedance tomography in neonates: a review. Pediatr Res 2025;epublished February 22nd
• Ebrahimi. Incidence of secondary pericardial effusions associated with different etiologies: a comprehensive review of literature. J Cardiothorac Surg 2025;20:141
• Castillo Diaz. A narrative review: Resuscitation of older adults with hemorrhagic shock. Transfusion 2025;epublished February 22nd
• Westphal. Biomarkers of Rejection in Kidney Transplantation. Am J Kidney Dis 2025;85(3):364-374
• Muhs. Anti-inflammatory Therapies for Ischemic Heart Disease. Curr Cardiol Rep 2025;27:57
• Harder. The association of ventilator mechanical power with weaning outcomes in intensive care unit patients: a narrative review. J Thorac Dis 2025;17(1):487-495
• Neilly. Non-Specific Pleuritis: An Update. Curr Pulmonol Rep 2025;14:7

Editorials

• Tempe. The conundrum of perioperative management of patients with diastolic dysfunction undergoing cardiac surgery. J Cardiothorac Vasc Anesth 2025;epublished February 22nd
• Siddiqui. Angiotensin II in Vasoplegia: Expanding Frontiers in Hemodynamic Therapy. J Cardiothorac Vasc Anesth 2025;epublished February 21st
• Joshi. A critical approach to research on perioperative pain management. Br J Anaesth 2025;134(3):621-626
• Scudellari. A Pragmatic View on General Anesthesia in Mechanical Thrombectomy for Acute Ischemic Stroke. Braz J Anesthesiol 2025;epublished February 18th
• Ryan. Mechanical circulatory support in cardiogenic shock: translating trial evidence into real-world practice. Open Heart 2025;12:e002863

Commentaries

• Noitz. Physiologic transfusion thresholds, better than using Hb-based thresholds? Blood Transfus 2024;23(1):96–100
• Thery. Expert Opinion: ECLS-SHOCK Trial. Semin Thorac Cardiovasc Surg 2025;epublished February 20th
• Siddiqui. Angiotensin II in Vasoplegia: Expanding Frontiers in Hemodynamic Therapy. J Cardiothorac Vasc Anesth 2025;epublished February 21st
• Braunwald. From cardiorenal to cardiovascular–kidney–metabolic syndromes. Eur Heart J 2025;46(8):682–684

Correspondence

• Ji. Sepsis-induced coagulopathy (SIC) in the management of sepsis. Ann Intensive Care 2025;15:23
• Mesquida. Assessing fluid responsiveness with central venous oxygen saturation: the complex relationship between oxygenation and perfusion. Crit Care 2025;29:85
• Kumar. From Rescue to Prevention: Prophylactic Hydroxocobalamin Shows Promise in Mitigating Vasoplegic Shock Post-Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth 2025;epublished February 20th

Case Reports

• Nanashima. Managing uncontrolled bleeding in elective surgery: The role of damage control techniques. Int J Surg Case Rep 2025;epublished February 19th

Saturday 22nd

Guidelines & Position Statements

• Lee. Nutritional support for critically ill patients by the Korean Society for Parenteral and Enteral Nutrition — part I: a clinical practice guideline. Ann Clin Nutr Metab 2024;16(3):89-111
• Society of Critical Care Medicine Guidelines for the Treatment of Heat Stroke. Crit Care Med 2025;53(2):e490-e500
• Society of Critical Care Medicine Guidelines on Adult Critical Care Ultrasonography: Focused Update 2024. Crit Care Med 2025;53(2):e447-e458
  • Executive Summary: Guidelines on Adult Critical Care Ultrasonography: Focused Update 2024. Crit Care Med 2025;53(2):e441-e446
• Society of Critical Care Medicine Guidelines on Family-Centered Care for Adult ICUs: 2024. Crit Care Med 2025;53(2):e465-e482
  
  • Hwang. Executive Summary: Society of Critical Care Medicine Guidelines on Family-Centered Care for Adult ICUs. Crit Care Med 2025;53(2):e459-e464

Friday 21st

Guidelines & Position Statements

• Choudhury. Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia. Hepatol Int 2025;epublished February 21st
• Environmental Sustainability in ICUs: A Report From the Society of Critical Care Medicine Sustainability Task Force. Crit Care Med 2025;epublished February 21st
• Society of Critical Care Medicine 2024 Guidelines on Adult ICU Design. Crit Care Med 2025;epublished February 21st
  • Society of Critical Care Medicine 2024 Guidelines on Adult ICU Design: Executive Summary. Crit Care Med 2025;epublished February 21st
• The Definition of the Intensivist in the Era of Global Healthcare: 2024 Consensus Statement From the Society of Critical Care Medicine Defining Intensivist Task Force. Crit Care Med 2025;epublished February 21st
• Lewis. A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med 2025;epublished February 21st
  • Lewis. Executive Summary of a Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med 2025;epublished February 21st
• Graham. Reducing global inequities in medical oxygen access: the Lancet Global Health Commission on medical oxygen security. Lancet Glob Health 2025;epublished February 3rd
  • Commentary: Baker. Realising the benefits of oxygen through essential emergency and critical care. Lancet Glob Health 2025;epublished February 3rd

Thursday 20th

Research

Randomised Controlled Trials

• Goret. Impact of non-invasive ventilation before and after cardiac surgery for preventing cardiac and pulmonary complications: a clinical randomized trial. Chest 2025;epublished February 19th
• Qian. Normosol-R versus Lactated Ringers in the Critically Ill: A Randomized Trial. Chest 2025;epublished February 17th
• Franck. Continuous glucose monitoring for hyperglycemia in critically ill patients: a randomized controlled trial. Chest 2025;epublished February 14th

Wednesday 19th

Narrative Review

Clinical

• Marrapu. Transition from acute kidney injury to chronic kidney disease in liver cirrhosis patients: Current perspective. World J Nephrol 2025;14(1):102381
• Ammirati. Acute myocarditis: 2024 state of the art. Eur Heart J Suppl 2025;27(1):i56–i60
• Zedde. Spinal Cord Infarction: Clinical and Neuroradiological Clues of a Rare Stroke Subtype. J Clin Med 2025;14:1293
• Piland. Substance-Use Disorders in Critically Ill Patients: A Narrative Review. Anesth Analg 2025;140(3):604-615

Pre-Clinical

• Yu. Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism. ICMx 2025;13:20

Tuesday 18th

Research

Randomised Controlled Trials

• Enne. INHALE WP3, a multicentre, open-label, pragmatic randomised controlled trial assessing the impact of rapid, ICU-based, syndromic PCR, versus standard-of-care on antibiotic stewardship and clinical outcomes in hospital-acquired and ventilator-associated pneumonia. Intensive Care Med 2025;epublished February 17th

Systematic Review & Meta Analyses

• Blot. Liberal vs. restrictive transfusion strategies for acute brain injury: a systematic review and frequentist-Bayesian meta-analysis. Intensive Care Med 2025;epublished February 17th

Observational Studies

• Gómez. Persistent severe acute kidney injury is a major modifiable determinant of outcome during critical illness. Intensive Care Med 2025;epublished February 17th
• Olmos. Effectiveness of bundle of care on tolerance of awake-prone positioning in patients with acute respiratory failure. A multicenter observational study. Intensive Care Med 2025;epublished February 17th

Editorials

• Hutchings. How we use ultrasound in the initial management of the critically ill trauma patient. Intensive Care Med 2025;epublished February 17th
• Siddiqui. Cultivating cultural competence in ICU communication. Intensive Care Med 2025;epublished February 17th

Narrative Reviews

Clinical

• Epelbaum. Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit. Intensive Care Med 2025;epublished February 17th

Monday 17th

Narrative Reviews

Non-Clinical

• Heuts. Bayesian Analytical Methods in Cardiovascular Clinical Trials: Why, When, and How. Can J Cardiol 2025;41(1):30-44
• Chesnaye. Non-linear relationships in clinical research. Nephrology Dialysis Transplantation 2025;40(2):244–254
• Gorst. Developing Core Outcome (Measurement) Sets for Critical Care Research Using the Modified Delphi Method. A Narrative Review. Chest Crit Care 2025;epublished Jabuary 16th
• Riley. Uncertainty of risk estimates from clinical prediction models: rationale, challenges, and approaches. BMJ 2025;388:e080749

Pre-Clinical

• Zhang. Dysregulation of neutrophil in sepsis: recent insights and advances. Cell Commun Signal 2025;23:87

Sunday 16th

Narrative Reviews

Clinical

• Gómez-Johnson. Point-of-care ultrasound in nephrology: beyond kidney ultrasound. Diagnostics 2025;15(3):297
• Ghabril. Drug‐induced liver injury in patients with chronic liver disease. Liver Int 2025;45(3):e70019
• Leo. Feasibility and role of cardiac magnetic resonance in intensive and acute cardiovascular care. J Clin Med 2025;14(4):1112
• Sardone. Management of vascular access in the setting of percutaneous mechanical circulatory support (pMCS): sheaths, vascular access and closure systems. J Pers Med 2023;13(2):293
• So. The role of a cardiogenic shock team in decision making surrounding mechanical circulatory support. Can J Cardiol 2025;epublished February 7th
• Zakynthinos. Septic cardiomyopathy: difficult definition, challenging diagnosis, unclear treatment. J Clin Med 2025;14(3):986
• Bankole. Minimally invasive surgery for spontaneous intracerebral hemorrhage: a review. J Clin Med 2025;14:1155
• Nasim. Clinical outcomes of machine perfusion and temperature control systems in heart transplantation: where we stand. J Clin Med 2025;14:1152
• Serlis. Complex limb injuries: limb salvage versus amputation—a mini review and meta-analysis. Adv Orthop 2025;2884802
• Siddiqui. Recent advances in cardiac resynchronization therapy: current treatment and future direction. J Clin Med 2025;14(3):889
• Valainathan. Prognosis algorithms for acute decompensation of cirrhosis and ACLF. Liver Int 2024;45(3):e15927
• Garde. Review article: somatization disorders in emergency department: a critical overview of current challenges and future directions. Emerg Med Australas 2025;37(1):e70009
• La Via. Critical care pharmacology of antiretroviral therapy in adults. Eur J Drug Metab Pharmacokinet 2025;epublished February 12th
• Bertini. Rising above the limits of critical care ECMO: a narrative review. Medicina 2025;61:174
• De Rosa. The future of artificial intelligence using images and clinical assessment for difficult airway management. Anesth Analg 2025;140(2):317-325
• Liu. A review of advances in multimodal treatment strategies for chronic disorders of consciousness following severe traumatic brain injury. Int J Gen Med 2025;epublished February 14th
• Zhou. Pathophysiological mechanisms of ARDS: a narrative review from molecular to organ-level perspectives. Respir Res 2025;26(1):54
• Camaj. Drug-coated balloons for the treatment of coronary artery disease: a review. JAMA Cardiol 2025;10(2):189-198
• Koratala. HepatoCardioRenal syndrome: integrating pathophysiology with clinical decision-making via POCUS. Cardiorenal Med 2025;epublished February 11th
• Honoré. Early detection, diagnosis, prevention, and treatment of infection to avoid sepsis and septic shock in severely burned patients: a narrative review. Eur Burn J 2025;6:6
• Guevarra. Point-of-care ultrasonography in the critical care unit: an update. Curr Cardiol Rep 2025;27(1):54
• Dost. Regional anesthesia for pediatric cardiac surgery: a review. BMC Anesthesiol 2025;25:77
• Tarr. Emergency management of intoxication‐type inherited metabolic disorders. J Inherit Metab Dis 2025;48(2):e70007
• Sumi. Pathophysiology, symptoms, outcomes, and evaluation of hyponatremia: comprehension and best clinical practice. Clin Exp Nephrol 2025;29:134–148
• Gunst. On how to feed critically ill children in intensive care: a slowly shifting paradigm. Clin Nutr 2025;46:169-180

Guidelines & Position Statements

• Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis 2025;epublished February 13th
• Niedzwecki. Early initiation of rehabilitation therapies in children with severe traumatic brain injury: an algorithm based on expert panel recommendations. J Trauma Acute Care Surg 2025;epublished February 6th
• 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery. Br J Anaesth 2025;epublished February 14th
• Indocyanine green fluorescence-guided surgery in the emergency setting: the WSES international consensus position paper. World J Emerg Surg 2025;20(1):13
• ORCHESTRA Delphi Consensus: diagnostic and therapeutic management of SARS-CoV-2 infection in solid organ transplant recipients. Clin Microbiol Infect 2025;epublished February 13th

Editorials

• Twagirumugabe. The new global definition of ARDS: a broader global lens on the care of patients with ARDS. Chest Crit Care 2024;epublished December 19th
• Rubin. Venovenous extracorporeal membrane oxygenation in patients with shock: considerations for candidacy selection. Chest Crit Care 2024;epublished December 19th
• Zanierato. The anesthetist perspective: optimization of cardiac allograft from withdrawal of life support to reperfusion in the controlled donation after circulatory death. Ann Cardiothorac Surg 2025;14(1):58-60
• Clark. Ethical considerations in controlled donation after circulatory death. Ann Cardiothorac Surg 2025;14(1):61-63

Commentaries

• Cotter. Increasing evidence supports the benefits of rapid uptitration of the neurohormonal blockade in HFmrEF/HFpEF patients with AHF. J Card Fail 2025;epublished February 11th
• Mahar. Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials 2025;26(1):49
• Ostertag. My journey through my husband’s coma. Intensive Care Med 2025;epublished February 13th

Saturday 15th

Research

Randomised Controlled Trials

• Dudeja. Early hydrocortisone versus placebo in neonatal shock - a double-blind randomized controlled trial. J Perinatol 2025;epublished February 13th
• Zou. Physiologic comparison of airway pressure release ventilation and low tidal volume ventilation in ARDS: a randomized controlled trial. Chest 2025;167(2):453-465
• Christenson. Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study. Lancet 2025;405(10478):571-582
• Hill. Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial. Lancet 2025;405(10478):560-570
• Capdevila. Ultrasound-guided transcutaneous phrenic nerve stimulation in critically ill patients: a new method to evaluate diaphragmatic function. Anesthesiology 2025;142(3):522-531
• Shankar-Hari. A randomized, double-blind, placebo-controlled trial of IL-7 in critically ill COVID-19 patients. JCI Insight 2025;epublished February 4th
• McMichael. Prospective randomized pilot study comparing bivalirudin versus heparin in neonatal and pediatric extracorporeal membrane oxygenation. Ped Crit Care Med 2025;26(1):e86-e94

Systematic Reviews & Meta Analyses

• Gajardo. Early high-sensitivity troponin elevation and short-term mortality in sepsis: a systematic review with meta-analysis. Crit Care 2025;29:76
• Dahms. Effectiveness of antibiotic prophylaxis in polytrauma patients: a systematic review and meta-analysis. Eur J Trauma Emerg Surg 2025;51(1):105
• Xing. Comparing adsorptive blood purification modalities for sepsis patients: a systematic review and network meta-analysis. Respir Med 2025;epublished February 12th
• Ma. Effect of liberal glucose control on critically ill patients: a systematic review and meta-analysis. BMC Endocr Disord 2025;25:36
• Špoljar. Ethics and end-of-life in pediatric and neonatal ICUs: a systematic review of recommendations. BMC Palliat Care 2025;24:36

Observational Studies

• Wolf. Acute pulmonary embolism in children and adolescents in the USA (2016 and 2019): a nationwide retrospective cohort study. Lancet Respir Med 2025;epublished February 4th
• Mitting. Sedation and ventilator weaning bundle and time to extubation in infants with bronchiolitis: secondary analysis of the Sedation AND Weaning in Children (SANDWICH) trial. Ped Crit Care Med 2025;epublished February 12th
• Betensky. Mechanical thromboprophylaxis and hospital-acquired venous thromboembolism among critically ill adolescents: a U.S. Pediatric Health Information Systems registry study, 2016–2023. Ped Crit Care Med 2025;26(1):e33-e41
• Jakobsen. Semi-autonomous drone delivering automated external defibrillators for real out-of-hospital cardiac arrest: a Danish feasibility study. Resuscitation 2025;epublished February 15th
• Michel-Behnke. Landiolol is effective and safe in paediatric supraventricular tachycardia: evidence from a European prospective multicentre open-label Phase III study (LANDI-PED). EP Europace 2025;epublished February 14th
• Kim. Diastolic blood pressures and end tidal carbon dioxides during cardiopulmonary resuscitations and their association with outcomes in adult out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the Augmented Medication CardioPulmonary Resuscitation (AMCPR) trial. Resuscitation 2025;epublished February 12th
• Buiteman-Kruizinga. Association of ventilation volumes, pressures and rates with the mechanical power of ventilation in patients without acute respiratory distress syndrome: exploring the impact of rate reduction. Anaesthesia 2025;epublished January 13th
• Kyriakopoulos. Informing management of patients developing cardiogenic shock at a spoke and being transferred to a hub. J Am Heart Assoc 2025;epublished February 14th
• Aissaoui. Diagnostic performance and impact on antimicrobial treatment of a multiplex polymerase chain reaction in critically ill patients with pneumonia: a multicenter observational study (The MORICUP-PCR Study: Morocco ICU Pneumonia-PCR study). Crit Care Explor 2025;7(2):e1220

Protocols and SAPS

• Zaloumis. TARGET Protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes—statistical analysis plan for a cluster randomized, cross-sectional, double cross-over, clinical trial. Trials 2025;26:42

Narrative Reviews

Clinical

• Fernández-Sarmiento. The Resuscitation, Equilibrium and De-escalation (RED) strategy: a phased, personalized hemodynamic support in children with sepsis. Front Pediatr 2025;13:1530984
• Cuttone. An Updated Review on the Use of Noninvasive Respiratory Supports in the Management of Severe Asthma Exacerbations. Medicina 2025;61:328

Correspondence

• Gelbenegger. Amiodarone dose in patients with shockable out-of-hospital cardiac arrest. Resuscitation 2025;epublished February 11th
• Wolff. Revisiting priorities in resuscitative hysterotomy. Resuscitation 2025;epublished February 12th
• Diop. The acute microbiota injury. Crit Care 2025;29:74

Case Reports

• Diop. The acute microbiota injury. Crit Care 2025;29:74
• Schram. POCUS and pre-eclampsia: bedside echocardiography to guide resuscitation in cardiogenic shock with pre-eclampsia with severe features – a case report from a low and middle income country. Int J Obstet Anesth 2025;62:104342
• Carron. Near-infrared spectroscopy during organ donation in brain-dead patients. Indian J Anaesth 2024;68(12):1095-1098
• Shi. An immunocompetent 56-year-old woman with multiple enlarged lymph nodes and recurrent fevers. Chest 2025;167(2):e41-e45
• Naiditch. A 40-year-old with prior stem cell transplant for chronic myeloid leukemia presents with dyspnea and respiratory failure. Chest 2025;167(2):e47-e51
• Wade. A 21-year-old man with unilateral chest pain, lobar consolidation, and pleural effusion. Chest 2025;167(2):e53-e56
• Wang. Echocardiographic image of left ventricular thrombus formation during cardiac contractility recovery under extracorporeal membrane oxygenation support. Chest 2025;167(2):e57-e62

Friday 14th

Narrative Reviews

Clinical

• Brooke. Ten tips on how to reduce iatrogenic acute kidney injury. Clin Kid J 2025;18(2):sfae412
• Luk. The Etiology and Management of Critical Acute Right Heart Failure. Can J Cardiol 2025;epublished February 10th

Thursday 13th

Narrative Reviews

Clinical

• Silva. Beyond the Lungs: Extrapulmonary Effects of Non-Invasive and Invasive Ventilation Strategies. J Clin Med 2025;14(4):1242

Guidelines & Position Statements

• Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association. Circulation 2025;epublished February 13th

Editorials

• Hemphill. AI in neurocritical care: what to expect. Intensive Care Med 2025;epublished February 11th

Commentaries

• Patel. Death by p-value: the overreliance on p-values in critical care research. Crit Care 2025;29:73
• Smale. A checklist for environmentally responsible research within the ICU. Intensive Care Med 2025;epublished February 12th
• Farbu. Balloon occlusion of the aorta during cardiac arrest -a death blow to the intestines?. Scand J Trauma Resusc Emerg Med 2025;33:24 

Wednesday 12th

Narrative Reviews

Clinical

• Ramirez. Anesthesia and EMI: Ensuring Safe CIED Management During Surgical Procedures. J Cardiothorac Vasc Anesth 2025;epublished February 11th
• Slot. Update on traumatic brain injury in the ICU. Curr Opin Anesthesiol 2025;epublished February 12th
• Algahtani. Ventilation and Oxygenation During and After Adult Cardiopulmonary Resuscitation: Changing Paradigms. Respir Care 2024;69(12):1573-1586
• Rowland. Supporting the bereaved child in the adult ICU: a narrative review. Intensive Care Med 2025;epublished February 12th

Tuesday 11th

Research

Randomised Controlled Trials

• Dijk. Evaluation of a Clinical Decision Support System for Imaging Requests. A Cluster Randomized Clinical Trial. JAMA 2025;epublished February 10th
• Cosgrave. Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study. Intensive Care Med Exp 2025;13(1):15

Systematic Reviews & Meta Analyses

• Farley. The Effects of Inspiratory Muscle Training in Critically ill Adults: A Systematic Review and Meta-Analysis. J Intensive Care Med 2025;epublished February 9th
• Guan. High-flow nasal oxygen therapy in patients with hypercapnic respiratory failure: A systematic review and meta-analysis. Eur J Intern Med 2025;epublished February 8th

Observational Studies

• Ramanan. Serum chloride concentration and outcomes in adults receiving intravenous fluid therapy with a balanced crystalloid solution or 0.9% sodium chloride. Intensive Care Med 2025;epublished February 10th
• Kumta. Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. Int J Antimicrob Agents 2025;epublished February 7th
• Hollmén. Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial. Neurocrit Care 2025;42(1):131-141
• Petrosino. Neurological Pupil Index and Intracranial Hypertension in Patients With Acute Brain Injury: A Secondary Analysis of the ORANGE Study. JAMA Neurol 2025;82(2):176-184

Guidelines & Position Statements

• Frontera. Guidelines for Seizure Prophylaxis in Patients Hospitalized with Nontraumatic Intracerebral Hemorrhage: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society. Neurocrit Care 2025;42:1–21

Commentaries

• Rossetti. Epileptiform Electrographic Patterns After Cardiac Arrest. Give Up or Treat? JAMA Neurol 2025;82(2):119-120

Monday 10th

Narrative Reviews

Clinical

• Zhang. Sepsis subphenotypes: bridging the gaps in sepsis treatment strategies. Front Immunol 2025;16:1546474
• Hung. Enhancing Care in Cardiogenic Shock: The Role of Palliative Care in Acute Cardiogenic Shock Through Destination Therapy. Can J Cardiol 2025;epublished February 4th
• Franciosi. Diffuse Cystic Lung Disease. A Clinical Guide to Recognition and Management. Chest 2025;167(2):529-547
• So. The Role of a Cardiogenic Shock Team in Decision Making Surrounding Mechanical Circulatory Support. Can J Cardiol 2025;epublished February 7th
• Karunakaran.Trace elements: Clinical perspectives in the critically ill. J Intensive Care Soc 2025;epublished February 5th
• Goldin. Reversal of Direct Oral Anticoagulants (DOACs) for Critical Bleeding or Urgent Procedures. J Clin Med 2025;14(3):1013

Guidelines & Position Statements

• Red Blood Cell Transfusion in Critically Ill Adults. An American College of Chest Physicians Clinical Practice Guideline. Chest 2025;167(2):477-489