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CCR Book 2016

Summarising, critiquing and putting in context the best critical care trials of 2015

We also provide one page summaries of the "best of the rest" trials, as well as a collection of the best free critical care guidelines

Selected Trials

HEAT Trial

Paracetamol for fever in patients with suspected infection

PROPPER Trial

Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio in patients with severe trauma:

SPLIT Trial

Effects of plasma-lyte vs 0.9% saline on acute kidney injury in the ICU

EUROTHERM 3235 Trial

Hypothermia for intracranial hypertension after traumatic brain injury

ProMISe Trial

Early, goal-directed therapy for septic shock

More Trials

Which site for central lines

3Sites Study

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An age old question

Steroids for Community-Acquired Pneumonia

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High Flow Nasal Oxygen

Florali Trial

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How effective is early CPR

Early CPR in Out-of-Hospital Cardiac Arrest

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Book Authors

Dr Peter McGuigan

Peter McGuigan is a consultant in ICM & anaesthesia in the Royal Victoria Hospital, Belfast. He attended Queen’s University Belfast and trained in Northern Ireland. He subsequently undertook a fellowship in the Royal Melbourne Hospital, Australia where he developed an interest in clinical governance. His main clinical interests are in post cardiac arrest care and anaesthesia for head and neck surgery.

Dr Chris Nutt

Chris is an intensivist & anaesthetist in the Royal Victoria Hospital, Belfast. He graduated from Queen’s University Belfast in 2001 and began training in Anaesthesia and Intensive Care in 2003. He has a strong research interest, publishing on pre operative risk assessment & has collaborated on several major international trials.

Dr Rob Mac Sweeney

Rob is an intensivist in the Regional Intensive Care Unit at the Royal Victoria Hospital, Belfast. He attended medical school at University College Dublin, undertook a PhD at Queen’s University Belfast and completed his anaesthetic and ICM training in Northern Ireland. He started Critical Care Reviews in 2009.

Yet More Trials

Erythropoietin in traumatic brain injury

EPO-TBI Trial

Age of Transfused Red cells in ICU Patients

ABLE Trial

Blood transfusion thresholds in upper GI bleeding

TRIGGER Trial

Prednisolone or Pentoxifylline for Alcoholic Hepatitis.

STOPAH Trial

Permissive Underfeeding or Standard Feeding

PERMIT Trial

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