Tuesday, October 29th

See. Metformin-associated lactic acidosis: A mini review of pathophysiology, diagnosis and management in critically ill patients. World J Diabetes 2024;15(6):1178-1186

Join us to read one paper per day and cover the spectrum of critical care across 2024. Previous papers of the day are available here.

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Mazzeffi. Prevention of Healthcare-associated Infections in Intensive Care Unit Patients. Anesthesiol 2021;135(6):1122-1131

Added October 27th

The WOMAN-2 Trial Collaborators. The effect of tranexamic acid on postpartum bleeding in women with moderate and severe anaemia (WOMAN-2): an international, randomised, double-blind, placebo-controlled trial. Lancet 2024;404(10463):1645-1656

Added October 26th

Capdevila. Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study. Intensive Care Med 2024;epublished October 25th

Added October 26th

Cardiac Arrhythmias and Autonomic Dysfunction Associated With COVID-19: A Scientific Statement From the American Heart Association. Circulation 2024;epublished October 14th

Added October 17th

Scott. Best Practices in Telecritical Care: Expert Consensus Recommendations From the Telecritical Care Collaborative Network. Crit Care Med 2024;52(11):1750-1767

Added October 17th

Jozwiak. Biomarkers in cardiogenic shock: old pals, new friends. Ann Intensive Care 2024;14:157

Added October 17th

Titanji. Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies. A Review. JAMA 2024;epublished October 14th

Added October 15th

White. Pathophysiology and Prevention of Manual-Ventilation-Induced Lung Injury (MVILI). Pathophysiology 2024;31:583-595

Added October 15th

Chen. Endovascular Stroke Thrombectomy for Patients With Large Ischemic Core. A Review. JAMA Neurol 2024;81(10):1085-1093

Added October 15th

Luis-Silva. Methylene blue therapy in addition to standard treatment for acute-phase septic shock: a pilot randomized controlled trial. Front Med 2024;11:1431321

Added October 14th

Ashoor. Outcomes of High-Dose Versus Low-Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation: A Randomized Controlled Trial. J Intensive Care Med 2024;39(10):1012-1022

Added October 14th

Wessels. Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage. A Randomized Clinical Trial. JAMA Neurol 2024;81(10):1060-1065

Added October 14th

Critical Care Reviews Newsletter 670, bringing you the best critical care research and open access articles for the week October 6th to 13th, 2024

Subscriptions are available to individuals and departments

added October 13th

Taccone. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury. The TRAIN Randomized Clinical Trial. JAMA 2024;epublished October 9th

Editorial: Turgeon. Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients—Is Less Still More? JAMA 2024;epublished October 9th

Added October 9th

Pereira. Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients. The TELESCOPE Randomized Clinical Trial. JAMA 2024;epublished October 9th

Editorial:  Vranas. Evaluating Complex Technological Innovations in Critical Care—Current Challenges and Future Directions. JAMA 2024;epublished October 9th

Added October 9th

Pérez-Fernández. Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery. The SIRAKI02 Randomized Clinical Trial. JAMA 2024;epublished October 9th

Editorial:  Kwong. Impact of Adsorptive Blood Purification on Kidney Outcomes. JAMA 2024;epublished October 9th

Added October 9th

Burns. Frequency of Screening and Spontaneous Breathing Trial Techniques. A Randomized Clinical Trial. JAMA 2024;epublished October 9th

Editorial:  Webb. Ventilator Weaning Strategies—Managing Interaction Between Randomized Treatments. JAMA 2024;epublished October 9th

Added October 9th

O'Grady. Leg Cycle Ergometry in Critically Ill Patients — An Updated Systematic Review and Meta-Analysis. NEJM Evidence 2024;epublished October 9th

Added October 9th

Cook. Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation. N Engl J Med 2024;391:9-20

(previously published)

Added October 9th

A supplemental Critical Care Reviews Newsletter, bringing you the research presented and published today at the ESICM 2024 Congress Hot Topics Session.

Subscriptions are available to individuals and departments

added October 9th

Egawa. Recovery of consciousness after acute brain injury: a narrative review. J Intensive Care 2024;12:37

Added September 27th

Carenzo. Contemporary management of traumatic cardiac arrest and peri-arrest states: a narrative review. J Anesth Analg Crit Care 2024;4:66

Added September 27th

Greer. Fever Prevention in Patients With Acute Vascular Brain Injury. The INTREPID Randomized Clinical Trial. JAMA 2024;epublished September 25th

Added September 25th

Jia. Effect of Delayed Remote Ischemic Preconditioning on Acute Kidney Injury and Outcomes in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial. Circulation 2024;epublished September 25th

Added September 25th

2024 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2024;epublished September 24th

Added September 25th

Borges. Organ crosstalk and dysfunction in sepsis. Ann Intensive Care 2024;14:147

Added September 20th

Rehberg. Landiolol for heart rate control in patients with septic shock and persistent tachycardia. A multicenter randomized clinical trial (Landi-SEP). Intensive Care Med 2024;epublished September 19th

Added September 19th

Richard. Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial. Intensive Care Med 2024;epublished September 17th

Added September 19th

Crippa. Brain hemodynamics in septic patients. Minerva Anestesiol 2024;90(9):814-29

Added September 17th

Luo. Effect of High-Intensity vs Low-Intensity Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseThe HAPPEN Randomized Clinical Trial. JAMA 2024;epublished September 16th

Added September 16th

Woo. Efficacy of Virtual Visitation in ICU During COVID-19 Pandemic: The ICU Visits Randomized Controlled Trial. Crit Care Med 2024;epublished September 17th

Added September 16th

Hariri. New drugs for acute kidney injury. J Intensive Med 2024;epublished September 7th

Added September 9th

von Düring. Understanding ventilator-induced lung injury: The role of mechanical power. J Crit Care 2025;85:154902

Added September 9th

Feys. Influenza-associated and COVID-19-associated pulmonary aspergillosis in critically ill patients. Lancet Respir Med 2024;12(9):728-742

Added September 9th

Helms. Oxygen therapy in acute hypoxemic respiratory failure: guidelines from the SRLF-SFMU consensus conference. Ann Intensive Care 2024;14:140

Added September 8th

Estep. Recommendations for Multimodality Imaging of Patients With Left Ventricular Assist Devices and Temporary Mechanical Support: Updated Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr 2024;37(9):820-871

Added September 8th

Neurological monitoring and management for adult extracorporeal membrane oxygenation patients: Extracorporeal Life Support Organization consensus guidelines. Crit Care 2024;28:296

Added September 8th

Critical illness-related corticosteroid insufficiency: latest pathophysiology and management guidelines. Acute Crit Care 2024;39(3):331-340

Added September 3rd

Acute lung injury and post-cardiac arrest syndrome: a narrative review. J Intensive Care 2024;12:32

Added September 3rd

Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis. Intensive Care Med 2024;epublished September 2nd

Added September 3rd

European Respiratory Journal series on Pulmonary Hypertension

Savale. Transplantation, bridging, and support technologies in pulmonary hypertension. Eur Respir J 2024;epublished August 29th

Added September 2nd

European Respiratory Journal series on Pulmonary Hypertension

Kovacs. Definition, classification and diagnosis of pulmonary hypertension. Eur Respir J 2024;epublished August 29th

Added September 2nd

European Respiratory Journal series on Pulmonary Hypertension

Guignabert. Pathology and pathobiology of pulmonary hypertension: current insights and future directions. Eur Respir J 2024;epublished August 29th

Added September 2nd

Boesing. Positive end-expiratory pressure management in patients with severe ARDS: implications of prone positioning and extracorporeal membrane oxygenation. Crit Care 2024;28:277

Added August 26th

Kill. Airway management and ventilation techniques in resuscitation during advanced life support: an update. J Anesth Analg Crit Care 2024;4:58

Added August 26th

Gaisendrees. Controlled automated reperfusion of the whole body after cardiac arrest: Device profile of the CARL system. Artif Org 2024;epublished August 23rd

Added August 26th

Gil. Venous thromboembolism in the era of machine learning and artificial intelligence in medicine. Thrombosis Research 2022;epublished August 22nd

Added August 25th

Wang. Unveiling the Mysteries of Contrast-Induced Acute Kidney Injury: New Horizons in Pathogenesis and Prevention. Toxics 2024;12:620

Added August 25th

Fernández. Acute liver failure: A practical update. JHEP Rep 2024;6(9):101131

Added August 25th

Sarani. Contemporary management of patients with multiple rib fractures: What you need to know. J Trauma Acute Care Surg 2024;97(3):337-342

Added August 22nd

De Backer. Monitoring cardiac output. Intensive Care Med 2024;epublished August 5th

Added August 9th

Lopez. Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery: A Randomized Clinical Trial. JAMA Surg 2024;epublished August 7th

Added August 7th

The 8th and final trial to be added to the CCR Down Under Programme is ALBICS-AKI, comparing postoperative 20% albumin with standard care on the development of acute kidney injury after high-risk cardiac surgery.

Added August 7th

The 7th trial added to the CCR Down Under Programme is SAHaRA, comparing a liberal transfusion strategy (haemoglobin ≤100g/L) with a restrictive one (haemoglobin value of ≤80g/L) in patients with aneurysmal subarachnoid haemorrhage.

Added August 5th

The latest trial to present its results in Melbourne is SCREEN, investigating electronic early notification of sepsis in hospitalized ward patients

Added August 2nd

The latest trial to present its results in Melbourne is TRAUMOX-2, comparing restrictive with liberal oxygen strategies for trauma patients

Added August 1st