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image: shutterstock / Amnaj Khetsamtip


The first trials for the Critical Care Reviews Meeting 2025 have started to be announced.

Join us in June to hear the best critical care trials in the world.

added January 8th

The Critical Care Reviews Meeting is a focused trials meeting. We host the results of the most impactful and important critical care trials in the world. In 2024, between our Belfast and Melbourne meetings, we hosted 19 major trial results, plus many accompanying systematic reviews and meta analyses.

Many of these presentations were in conjunction with simultaneous publications in the New England Journal of Medicine, JAMA and NEJM Evidence.

If you haven't been yet, check out our video - there's no other meeting like it.

Trial Announcements


updated January 10th


PREOXI presentation at CCR24

Jonathan Casey and Kevin Gibbs present the results of the PREOXI trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast. PREOXI investigated non-invasive ventilation for preoxygenation in emergency intubation in the critically ill.

Yonathan Freund delivers an independent editorial. Catriona Kelly chairs a panel discussion with Anthony Gordon, Sheila Myatra, Victoria Cornelius and Jan Gunst.

PREOXI was simultaneously published in the New England Journal of Medicine.

added January 9th


FAST scan with liver and kidney identified

Paper of the Day

Friday, January 10th

Meyfroidt. Management of moderate to severe traumatic brain injury: an update for the intensivist. Intensive Care Med 2022;48:649–666

Join us to read one paper per day and cover the spectrum of critical care across 2024. Previous papers of the day are available here.

Have it emailed to you!

image: Shutterstock / Aleksandr Finch

DEFENDER presentation at CCR24

Profs Caio Tavares and Fernando Zampieri present the results of the DEFENDER trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

DEFENDER investigated the efficacy of dapagliflozin in the critically ill.

Danny McAuley delivers an independent editorial and Christopher Seymour chairs a panel discussion between Simon Finfer, Lennie Derde, Marion Campbell and Catherine McKenzie.

DEFENDER was simultaneously published in JAMA.

added January 7th


REVISE presentation at CCR24

Deborah Cook and Adam Deane present the results of the REVISE trial, plus an accompanying systematic review and meta analysis, at the Critical Care Reviews Meeting 2024, in Titanic Belfast.

REVISE investigates the efficacy of stress ulcer prophylaxis with pantoprazole in critically ill mechanically ventilated patients.

Kathy Rowan delivers an editorial and Darren Taichman chairs a panel discussion between David Harrison, Martina Baiardo Redaelli, Madiha Hasmi and Danny McAuley.

REVISE was simultaneously published in the New England Journal of Medicine. The SRMA was simultaneously published in NEJM Evidence.

added January 6th


CCR Newsletter logo

Newsletter 682

Critical Care Reviews Newsletter 682, bringing you the best critical care research and open access articles for the week December 30th to January 5th.

Subscriptions are available to individuals and departments.

added January 5th


CCR Down Under 2025

Week of December 8th

Due to the success of CCR Down Under, we're heading back to Melbourne in December 2025 for another 2 day event.

Join us in the Edge, Federation Square, to hear the results of the best critical care trials in the world.

Registration will open in May.

CCR Down Under is run in partnership with The Alfred Intensive Care Academic Centre.

Audience at CCR Down Under raising their hands




Latest RCTs


Updated January 2nd


Latest Guidelines


Updated January 2nd