Struggling to keep up with the literature?
We've been tracking it daily for over 15 years.
Get the most comprehensive collection of the latest critical care literature, delivered straight to your inbox every week. From landmark studies to must-read reviews, the Critical Care Reviews Newsletter ensures you’re always up-to-date, without the hassle.
Individual and unit subscriptions are available. There's nothing like it.
image: shutterstock / Amnaj Khetsamtip
The first trials for the Critical Care Reviews Meeting 2025 have started to be announced.
Join us in June to hear the best critical care trials in the world.
added January 8th
The Critical Care Reviews Meeting is a focused trials meeting. We host the results of the most impactful and important critical care trials in the world. In 2024, between our Belfast and Melbourne meetings, we hosted 19 major trial results, plus many accompanying systematic reviews and meta analyses.
Many of these presentations were in conjunction with simultaneous publications in the New England Journal of Medicine, JAMA and NEJM Evidence.
If you haven't been yet, check out our video - there's no other meeting like it.
Trial Announcements
updated January 10th
PREOXI presentation at CCR24
Jonathan Casey and Kevin Gibbs present the results of the PREOXI trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast. PREOXI investigated non-invasive ventilation for preoxygenation in emergency intubation in the critically ill.
Yonathan Freund delivers an independent editorial. Catriona Kelly chairs a panel discussion with Anthony Gordon, Sheila Myatra, Victoria Cornelius and Jan Gunst.
PREOXI was simultaneously published in the New England Journal of Medicine.
added January 9th
Paper of the Day
Friday, January 10th
Join us to read one paper per day and cover the spectrum of critical care across 2024. Previous papers of the day are available here.
Narrative Review
added January 8th
Guideline
added January 8th
DEFENDER presentation at CCR24
Profs Caio Tavares and Fernando Zampieri present the results of the DEFENDER trial at the Critical Care Reviews Meeting 2024, in Titanic Belfast.
DEFENDER investigated the efficacy of dapagliflozin in the critically ill.
Danny McAuley delivers an independent editorial and Christopher Seymour chairs a panel discussion between Simon Finfer, Lennie Derde, Marion Campbell and Catherine McKenzie.
DEFENDER was simultaneously published in JAMA.
added January 7th
Narrative Review
added January 8th
Editorial
added January 7th
Editorial
added January 7th
REVISE presentation at CCR24
Deborah Cook and Adam Deane present the results of the REVISE trial, plus an accompanying systematic review and meta analysis, at the Critical Care Reviews Meeting 2024, in Titanic Belfast.
REVISE investigates the efficacy of stress ulcer prophylaxis with pantoprazole in critically ill mechanically ventilated patients.
Kathy Rowan delivers an editorial and Darren Taichman chairs a panel discussion between David Harrison, Martina Baiardo Redaelli, Madiha Hasmi and Danny McAuley.
REVISE was simultaneously published in the New England Journal of Medicine. The SRMA was simultaneously published in NEJM Evidence.
added January 6th
Observational Study
Added January 7th
Newsletter 682
Critical Care Reviews Newsletter 682, bringing you the best critical care research and open access articles for the week December 30th to January 5th.
Subscriptions are available to individuals and departments.
added January 5th
Meta Analysis
NAVIGATE presentation at CCR24
Profs Giacomo Monti and Giovanni Landoni present the results of the NAVIGATE trial at the Critical Care Reviews Meeting 2024 in Titanic Belfast.
added January 2nd
RCT
Meta Analysis
Added January 2nd
RCT
Added January 1st
Observational Study
Added January 1st
Narrative Review
Reignier. Nutritional Support in the ICU. BMJ 2025;388:e077979
Added January 3rd
CCR Down Under 2025
Week of December 8th
Due to the success of CCR Down Under, we're heading back to Melbourne in December 2025 for another 2 day event.
Join us in the Edge, Federation Square, to hear the results of the best critical care trials in the world.
Registration will open in May.
CCR Down Under is run in partnership with The Alfred Intensive Care Academic Centre.
Narrative Review
Added December 30th
Narrative Review
Added December 30th
Narrative Review
Added December 30th
Narrative Review
Added December 30th
Narrative Review
Lee. Intracerebral hemorrhage. Cerebrovasc Dis Extra 2025;15(1):1-8
Added December 30th
Editorial
Added December 30th
Editorial
Added December 30th
Commentary
Myriam. Red blood cell transfusion in brain injury: Is it solely a matter of hemoglobin threshold?. Crit Care 2024;28:430
Added December 30th
Commentary
Added December 30th
Commentary
Added December 30th
Latest RCTs
Updated January 2nd
Latest Guidelines
Updated January 2nd