CCR-Newsletter-BannerNewsletter 460  |  October 4th 2020

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Welcome to the 460th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on early mechanical ventilation in patients with Guillain-Barré syndrome at high risk of respiratory failure & hydroxychloroquine for pre-exposure SARS-CoV-2 prophylaxis among health care workers; systematic reviews and meta analyses on the efficacy and safety of in–ICU leg-cycle ergometry & the association of weaning failure from mechanical ventilation with transthoracic echocardiography parameters; and observational studies on epinephrine’s effects on cerebrovascular and systemic hemodynamics during CPR & surgical mask on top of high-flow nasal cannula in critically ill COVID-19 patients with hypoxemic respiratory failure.

There are also guidelines on critically ill children with COVID-19 & anaesthesia during the COVID-19 pandemic; narrative reviews on hospital-acquired and ventilator-associated pneumonia & Ileus in the critically ill; editorials on whether mortality is a useful endpoint in stress ulcer prophylaxis & COVID-19-related and non-COVID-related ARDS; and commentaries on mechanical ventilation in the obese patient, de-adopting low-value care & survival time as an endpoint in COVID-19 trials.

This week's Topic of the Week is diaphragmatic conditions, starting with a paper on critical illness-associated diaphragm weakness in tomorrow's Paper of the Day. If you only have time to read one review article this week, try this one on respiratory viral sepsis.

 

Research

Review Articles

COVID-19

Neurological

Circulatory

Respiratory

Gastrointestinal

Hepatobiliary

Renal

Endocrine

Sepsis

Trauma

Paediatrics

Miscellaneous

Commentaries

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

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