CCR-Newsletter-BannerNewsletter 441  |  June 9th 2020

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Welcome to the 441st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature for the week May 18th to 24th. There are two more newsletters coming out tomorrow and Thursday night, catching up on the other two weeks I'm behind on.

The highlights of this week's edition are two COVID-19 randomised controlled trials investigating remdesivir & the triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin; systematic reviews and meta analyses on periprocedural bridging anticoagulation & mortality in sepsis and septic shock in Europe, North America and Australia; and observational studies on the postmortem examination of patients with covid-19, an outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic & the latest publication from the RADAR project, describing the results of a survey on fluid management and deresuscitation practices.

There are guidelines on the treatment of cerebral edema & liver trauma; narrative reviews on acute kidney injury in patients with COVID-19 & non-ST-elevation myocardial infarction; editorials on renal replacement therapy initiation & unconventional approaches to mechanical ventilation; commentaries on accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) & universal masking in hospitals in the Covid-19 era.

This week 's Topic of the Week is cardiogenic shock - part II, continuing with a paper on devices for mechanical circulatory support in tomorrow's Paper of the Day.

If you only have time to read one article this week, try this one on a history of the medical mask and the rise of throwaway culture.





CCR21 Meeting

Due to the phenomenal success of CCR20, the Critical Care Reviews Meeting 2021 has been expanded to 3 days, allowing more time for major trial results presentations, as well as understanding the best clinical trials published during 2020. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until tomorrow night


Supported by the Health Research Board

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