CCR-Newsletter-BannerNewsletter 402  |  August 26th 2019

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 PEPTIC 2 Announcement 1000


Welcome to the 402nd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

It's been a big week for the Critical Care Reviews Meeting 2020, with the announcement we are to host the results of the ANZICS Clinical Trials Group PEPTIC trial, comparing proton pump inhibitors with histamine 2 receptor blockers in mechanically ventilated ICU patients. This huge multi-centre, cluster randomised, crossover, registry trial has recruited 26,733 patients. For those who can't make it to Titanic to hear Dr Paul Young present the results, we will live stream this worldwide, although it's far better to be there in person. You can also listen to the podcast I recorded with Dr Shay McGuinness, another senior investigator, a few years ago during the recruitment phase of PEPTIC.

If that wasn't enough, we have also added VITAMINS, another great ANZICS trial, to the CCR20 programme. This phase IIb trial investigates vitamin C, thiamine and hydrocortisone in patients with septic shock. It will be presented by Dr Tomoko Fujii from Melbourne. Finally, the videos from CCR19 continue to be released, with APPROCCHSS by Prof Djillali Annane, and its editorial by Dr Manu Shankar-Hari, plus Artificial Intelligence in Sepsis by Prof Anthony Gordon, with its editorial by Prof Kathy Rowan, all available this week just past. Another two sets of trial presentations will be released this week.

Registration for CCR20 is open, so don't delay too long and miss out the opportunity to discuss the best critical care trials of 2019 with their chief investigators, and hear the results of the PEPTIC trial.

I'll add this week's Topic of the Week in the morning.



Review Articles








CCR20 Meeting

CCR20 010819 Widget

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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