Welcome to the 384th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on restrictive IV fluids in sepsis and septic shock & screening for weaning from mechanical ventilation; systematic reviews and meta analyses on airway management during cardiac arrest & vasopressors during cardiac arrest; and observational studies on lactatemia in sepsis & quality of life and 1-year survival in the ARISE trial. There are also guidelines on diversity & cardiorenal syndrome; narrative reviews on cardiogenic shock, upper gastrointestinal bleeding & hepatorenal syndrome; and commentaries on broad spectrum vasopressors, early prophylactic hypothermia for patients with severe traumatic injury & liberal versus conservative oxygen therapy in critically ill patients.
If you only have time to read one review article this week, try this one on sepsis: evolving concepts and challenges.
- Abstract: Corl. The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS). A Randomized Pilot Study. Crit Care Med 2019;epublished April 12th
- Abstract: Burns. Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials. Crit Care Med 2019;epublished March 27th
- Full Text: Hotchkiss. Immune Checkpoint Inhibition in Sepsis. A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559). Crit Care Med 2019;47(5):632–642
- Abstract: Ferrando. High-flow nasal cannula oxygenation reduces postoperative hypoxemia in morbidly obese patients: a randomized controlled trial. Minerva Anestesiol 2019;epublished April 16th
- Full Text: Armstrong. The incidence of cardiac arrest in the intensive care unit: A systematic review and meta-analysis. JICS 2019;epublished May 10th
- Full Text: Cho. Impact of Preoperative Erythropoietin on Allogeneic Blood Transfusions in Surgical Patients: Results From a Systematic Review and Meta-analysis. Anesth Analg 2019;128(5):981-992
- Abstract: Granfeld. Advanced airway management during adult cardiac arrest: A systematic review. Resuscitation 2019;epublished April 11th
- Abstract: Holmberg. Vasopressors during adult cardiac arrest: A systematic review and meta-analysis. Resuscitation 2019;epublished April 10th
- Abstract: Cabrini. Awake Fiberoptic Intubation Protocols in the Operating Room for Anticipated Difficult Airway. A Systematic Review and Meta-analysis of Randomized Controlled Trials. Anesth Analg 2019;128(5):971–980
- Abstract: Gattinoni. Understanding lactatemia in human sepsis: potential impact for early management. Am J Respir Crit Care Med 2019;epublished April 15th
- Full Text: Aragón. Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort. Critical Care 2019;23:130
- Abstract: Higgins. Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial. Crit Care Med 2019;epublished April 8th
- Full Text: Merck. The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury. Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial. Crit Care Med 2019;47(5):623–631
- Full Text: Pepper. Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients. Crit Care Med 2019;47(5):643–650
- Abstract: Sprügel. Heparin for prophylaxis of venous thromboembolism in intracerebral haemorrhage. J Neurol Neurosurg Psychiatry 2019;epublished April 16th
- Full Text: Takegawa. Usefulness of Cerebral rSO2 Monitoring During CPR to Predict the Probability of Return of Spontaneous Circulation. Resuscitation 2019;epublished April 17th.
- Abstract: Sigal. Impact of adrenaline dose and timing on out-of-hospital cardiac arrest survival and neurological outcomes. Resuscitation 2019;epublished April 13th
- Vlaar. A consensus redefinition of transfusion‐related acute lung injury. Transfusion 2019;epublished April 16th
- Statement paper on diversity for the European Society of Intensive Care Medicine (ESICM). Intensive Care Med 2019;epublished April 4th
- Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association. Circulation 2019;139:e840–e878
- Leng. Treatment for ischemic stroke: From thrombolysis to thrombectomy and remaining challenges. Brain Circ 2019;5:8-11
- Gregori. Treatment algorithm for spontaneous spinal infections: A review of the literature. J Craniovertebr Junction Spine 2019;10(1):3–9
- Oddo. Update in Neurocritical Care: a summary of the 2018 Paris international conference of the French Society of Intensive Care. Annals of Intensive Care 2019;9:47
- Park. Endovascular Treatment of Acute Stroke Due to Intracranial Atherosclerotic Stenosis–Related Large Vessel Occlusion. Front Neurol 2019;10:308
- Samagh. Monitoring cerebral vasospasm: How much can we rely on transcranial Doppler. J Anaesthesiol Clin Pharmacol 2019;35:12-8
- Vahdatpour. Cardiogenic Shock. J Am Heart Assoc 2019;8:e011991
- Maisch. Cardio-Immunology of Myocarditis: Focus on Immune Mechanisms and Treatment Options. Front Cardiovasc Med 2019;6:48
- Xie. Drug Prevention and Control of Ventilator-Associated Pneumonia. Front Pharmacol 2019;10:298
- Kollisch-Singule. The time-controlled adaptive ventilation protocol: mechanistic approach to reducing ventilator-induced lung injury. Eur Respir Rev 2019;28:180126
- Long. Perioperative Considerations for Evolving Artificial Pancreas Devices. Anesth Analg 2019;128(5):902-906
- Lewis. Perioperative Management of Infants and Children With Diabetes. Anaesthesia Tutorial of the Week;epublished April 16th
- Salomão. Sepsis: evolving concepts and challenges. Brazilian Journal of Medical and Biological Research 2019;52(4):e8595
- Devauchelle. Mucormycosis in Burn Patients. J Fungi (Basel) 2019;5(1):25
- Beck. Biomarkers in Human Anaphylaxis: A Critical Appraisal of Current Evidence and Perspectives. Front Immunol 2019;10:494
- Meissen. Integrating Advanced Practice Providers Into the Multiprofessional Critical Care Team. Crit Care Med 2019;47(5):737–738
- Moningi. Enhanced recovery after surgery: An anesthesiologist's perspective. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:5-13
- Iqbal. Preoperative patient preparation in enhanced recovery pathways. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:14-23
- Patil. Implementing enhanced recovery pathways to improve surgical outcomes. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:24-8
- Kendrick. Goal-directed fluid therapy in the perioperative setting. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:29-34
- Kaye. Enhanced recovery pathways in orthopedic surgery. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:35-9
- Kaye. Multimodal analgesia as an essential part of enhanced recovery protocols in the ambulatory settings. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:40-5
- Elhassan. Perioperative surgical home models and enhanced recovery after surgery. J Anaesthesiol Clin Pharmacol 2019;35, Suppl S1:46-50
- Chawla. Broad spectrum vasopressors: a new approach to the initial management of septic shock? Critical Care 2019;23:124
- Chin. Early Prophylactic Hypothermia for Patients With Severe Traumatic Injury: Premature to Close the Case. Front Neurol 2019;10:344
- Farrington. Management of the Hemodialysis Patient with Catheter-Related Bloodstream Infection. Clin J Am Soc Nephrol 2019;14(4):611-613
- Shaw. Kidney Xenotransplantation. Clin J Am Soc Nephrol 2019;14(4):620-622
- Tomson. Stopping RAS Inhibitors to Minimize AKI. Clin J Am Soc Nephrol 2019;14(4):617-619
- Vargas. Liberal versus conservative oxygen therapy in critically ill patients: using the fragility index to determine robust results. Critical Care 2019;23:132
- Wood. Wood and Trees attend a conference. JICS 2019;20(2):187-188
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
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Until next week
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