CCR-Newsletter-BannerNewsletter 260  |  December 4th 2016

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Gattinoni Vincent cropped

The Great Debate at CCR16

RCTs are Killing Critical Care | Vincent: Damn Right! | Gattinoni: You're Having a Laugh?


Welcome to the 260th Critical Care Reviews Newsletter, which marks 5 years of consecutive weekly newsletters. The highlights of this week's newsletter are two RCTs on inhaled amikacin fosfomycin for gram negative VAP and clarithromycin-naproxen-oseltamivir for influenza A (H3N2), as well as reviews on Plasma-Lyte 148 and the inflammatory response to ECMO.

The Intensive Care Society's State-of-the-Art Meeting is on this week, including round two of the Great Debate from #CCR16 earlier this year. This time Jean-Louis Vincent takes on ANZICS' Steve Webb, again disputing the role of randomised controlled trials in critical care. Have a look at the fascinating discussion between Jean-Louis Vincent and Luciano Gattinoni in Belfast last January and make your own mind up. If you'd like to come to next month's Critical Care Reviews Meeting, John Myburgh will continue the theme in a talk called "The Path to Truth". Can't wait for this one! And speaking of talks from recent conferences, the plenary discussion on the future of publishing and knowledge dissemination from SMACC DUB has just been released. The next ticket allocation for dasSMACC in Berlin in June go on sale on Tuesday night, depending on where in the world you are.

There could only be one choice for the Topic of the Week, which is the randomised controlled trial, starting with an introduction to randomized trials in tomorrow's Paper of the Day.

If you'd like to work in the field of critical care social media, there is an opportunity to undertake a fellowship with me in Belfast, where you will learn a wide range of contemporary skills. This post is offered by the Belfast Health and Social Care Trust. Further details can be found here or contact me via email. There are also three other critical care fellowship available, in

The Regional Intensive Care Unit is a world class research hub and the home unit for the REST Trial, investigating extracorporeal CO2 removal in respiratory failure. All fellowships are available for a six month to one year duration, although it may be possible to facilitate longer periods.

See you in London. Please say hi if you're around.




Review Articles










American Journal of Respiratory & Critical Care Medicine



Case Reports




Anesthesia & Analgesia





Minerva Anaesthesiologica



CCR17 Poster

Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.

Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.


Following last year's massively successful event, the UK Intensive Care Society's State-of-the-Art Meeting is starting its build-up to 2016. The ICS completely changed its game in 2015, and relaunched SOA as a new beacon for forward-looking clinical content, open-access education, and medical social media. In keeping with the times, the podcasts and other materials from last year's meeting have been made open access.
This year the programme is looking even better, with topics ranging from the futuristic (space medicine, Formula 1 applied technology, Google Deepmind, and AI) through to the human, practical, and controversial (look out for the clinical scenarios, controversies, and the "From Ivory Tower to Desert Island" session).  Speakers include Peter Brindley, Kevin Fong, Jack Iwashyna, Kath Maitland, Louise Rose, Mervyn Singer, and Jean-Louis Vincent among many others.  It runs from Mon 5th - Wed 7th Dec, and I hope I'll see you there.  Keep an eye on for programme and registration, and meanwhile enjoy the comprehensive FOAM from last year.


The first release of tickets for Das SMACC sold out in just 2.5 hours this week. The next opportunity will be on Wednesday December 7th (depending on where you are in the world). If you haven't yet checked out the programme and workshops, then have a look on the SMACC website. The Hardcore Intensive Care workshop being organised by Steve Mathieu and Sarah Yong will cover all your critical care questions.


(Image from Chensiyuan via Wikipedia)

This adult and paediatric ICM meeting is jointly organized by the Society of Intensive Care Medicine (SICM), Singapore and the Australia-New Zealand Intensive Care Society (ANZICS) and is scheduled for 20-24 April 2017 in Suntec Convention Centre, Singapore. It has grown from its humble beginnings in a small hospital venue to become one of the best ICM conference in the Asia-Pacific region. Past editions featured prominent speakers such as Jean Louis Vincent, Daniel De Backer, John J Marini, Rinaldo Bellomo amongst many others, and in this edition the list of distinguished international panel of speakers, program schedule and planned workshops look more impressive than ever. Beside the obvious educational benefits, this conference is also a great opportunity to experience the unique Singaporean culture, enjoy its famed gastronomy and visit its attractions.

The call for abstracts have started and Education Grants are available for selected delegates. Registration for the conference and pre-conference workshops is now open and can be found here.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.


I hope you find these links useful.

Until next week