• Abstract:  van Lieshout. Nurses versus physician-led interhospital critical care transport: a randomized non-inferiority trial. Intensive Care Med 2016;epublished May 11th
• Full Text:  Jena. Comparison of suction above cuff and standard endotracheal tubes in neurological patients for the incidence of ventilator-associated pneumonia and in-hospital outcome: A randomized controlled pilot study. Indian J Crit Care Med 2016;20:261-6

• Abstract:  Veldeman. Delayed cerebral ischaemia prevention and treatment after aneurysmal subarachnoid haemorrhage: a systematic review. Br J Anaesth 2016;epublished May 8th
• Full Text:  Liu. Regional citrate versus heparin anticoagulation for continuous renal replacement therapy in critically ill patients: a meta-analysis with trial sequential analysis of randomized controlled trials. Crit Care 2016;20(1):144

• Full Text:  Yeung. Speckle tracking echocardiography in patients with septic shock: a case control study (SPECKSS). Critical Care 2016;20:145
• Full Text: Wafaisade. Prehospital administration of tranexamic acid in trauma patients. Critical Care 2016;20:143
• Full Text: Matsumura. Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study. Critical Care 2016;20:141
• Abstract:  Hagiwara. Can Early Aggressive Administration of Fresh Frozen Plasma Improve Outcomes in Patients with Severe Blunt Trauma?—a Report by the Japanese Association for the Surgery of Trauma. Shock 2016;45(5):495–501
• Abstract:  Cameron. One-Year Outcomes in Caregivers of Critically Ill Patients (RECOVER Program). N Engl J Med 2016;374:1831-1841
• Abstract:  Antonucci. The Impact of Renal Failure and Renal Replacement Therapy on Outcome During Extracorporeal Membrane Oxygenation Therapy. Artificial Organs 2016;epublished May 2nd
• Abstract:  Sjoding. Acute Respiratory Distress Syndrome Measurement Error: Potential Effect on Clinical Study Results. Annals ATS 2016;epublished May 9th
• Abstract:  Maley. Resilience in Survivors of Critical Illness in the Context of the Survivors’ Experience and Recovery. Annals ATS 2016;epublished May 9th

• Moreno. Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm. Cochrane Database of Systematic Reviews 2016, Issue 5. Art. No.: CD011664
• Hewitt. Lateral positioning for critically ill adult patients. Cochrane Database of Systematic Reviews 2016, Issue 5. Art. No.: CD007205
• Estcourt. Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD005339
• Griffiths. Intravenous magnesium sulfate for treating children with acute asthma in the emergency department. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD011050
• Prasad. Corticosteroids for managing tuberculous meningitis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD002244
• Gluud. Non-absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD003044
• Gurusamy. Interventions for necrotising pancreatitis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD011383
• Madrid. Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD009016

Neurological

• Gupta. Intensive care management of status epilepticus. J Neuroanaesthesiol Crit Care 2016;3:83-95
• Bindra. Targeted temperature management in neurocritical care: Boon or bust. J Neuroanaesthesiol Crit Care 2016;3:96-109
• Manara. A case for stopping the early withdrawal of life sustaining therapies in patients with devastating brain injuries. JICS 2016;epublished May 5th
• Kumar. Brain death and care of the organ donor. J Anaesthesiol Clin Pharmacol 2016;32:146-52
• Gorlin. Intravenous sub-anesthetic ketamine for perioperative analgesia. J Anaesthesiol Clin Pharmacol 2016;32:160-7
• Karnjuš. Inhalation sedation with the ‘Anaesthetic Conserving Device’ for patients in intensive care units: A literature review. SIGNA VITAE 2016; 11(1):1-24 

Circulatory

• Kulkarni. Extracorporeal membrane oxygenation in adults: A practical guide for internists. CCJM 2016;83(5):373-384

Respiratory

• Longworth. Tracheostomy in special groups of critically ill patients: Who, when, and where?. Indian J Crit Care Med 2016;20:280-4

Gastrointestinal

• Tang. Pseudomembranous colitis: Not always Clostridium difficile. CCJM 2016;83(5):361-366

Hepatobiliary

•  Gariani. Effects of liver transplantation on endocrine function: A systematic review. Liver Int 2016;epublished May 10th

Trauma

• Aboseif. Role of anesthesiologists in the management of trauma patients: Updates. Ain-Shams J Anaesthesiol 2016;9:153-8
• Godat. Thoracoscopic Management of Traumatic Sequelae. Curr Trauma Rep 2016;epublished April 30th
• Miller. Early Enteral Nutrition in Trauma: Is There Still Any Doubt? Curr Trauma Rep 2016;epublished April 29th
• Robins. Fracture Care Challenges in Austere and Combat Environments. Curr Trauma Rep 2016;epublished April 27th
• Gellman. Fracture Care Challenges in the Austere and Humanitarian Environments. Curr Trauma Rep 2016;epublished April 26th
• Shields. Cutting-Edge Forward Burn Nutrition: from the Battlefield to the Burn Center. Curr Trauma Rep 2016;epublished April 25th
• Kagan. Is Total Parenteral Nutrition (TPN) an Evil in Trauma Patients? Curr Trauma Rep 2016;epublished April 22nd
• Chouinard. The Acute Management of Facial Fractures. Curr Trauma Rep 2016;epublished April 15th
• Stump. Fat Embolism Syndrome: Fact or Myth? Curr Trauma Rep 2016;epublished April 15th

Miscellaneous

• Kaur. Amniotic fluid embolism. J Anaesthesiol Clin Pharmacol 2016;32:153-9
• Lipner. Evaluation of nail lines: Color and shape hold clues. CCJM 2016;83(5):385-391

• Grier. The relocation and road transfer of intensive care patients to a new hospital in Bristol: Our experiences. JICS 2016;epublished May 12th
• Anderson. Can open-source drug development deliver? Lancet 2016;387(10032):1983–1984
• Thomas. The United Kingdom National Audit Projects: a narrative review. South Afr J Anaesth Analg 2016;22(2):38–45
  
  • Editorial:  Kluyts. The United Kingdom National Audit Project Program - an opportunity for South Africa? South Afr J Anaesth Analg 2016;

• Bonaventure. Managing critically ill patients with severe traumatic brain injury: How should we season the recipe? Can J Anesth 2016;63:647–651
• Rasmussen. Enhanced recovery programmes for the elderly. European Journal of Anaesthesiology 2016;33(6):391–392
• Goyal. Dexmedetomidine: The game changer or a team player?. J Anaesthesiol Clin Pharmacol 2016;32:144-5
• Gracious. Maximizing organ yield from deceased Lead donors. J Anaesthesiol Clin Pharmacol 2016;32:143
• Protti. The delicate balance between pro-(risk of thrombosis) and anti-(risk of bleeding) coagulation during extracorporeal membrane oxygenation. Ann Transl Med 2016;4(7):139
• Rijkenberg. Can the critical-care pain observation tool (CPOT) be used to assess pain in delirious ICU patients? J Thorac Dis 2016;8(5):E285-E287
• Revest. Adjuvant corticosteroids for patients hospitalized with community-acquired pneumonia: is it time? J Thorac Dis 2016;8(5):E288-E291
• Trivedi. Utility of the Richmond Agitation-Sedation Scale in evaluation of acute neurologic dysfunction in the intensive care unit. J Thorac Dis 2016;8(5):E292-E294
• Cobianchi. Serum lactate level as a useful predictor of clinical outcome after surgery: an unfulfilled potential? J Thorac Dis 2016;8(5):E295-E297

• Jones. Publication bias in the anesthesiology literature: shifting the focus from the “positive” to the “truth”. Can J Anesth 2016;63:658-663

• Gattinoni. Ultra-protective ventilation and hypoxemia. Critical Care 2016;20:130
• Bozza. Key points on Zika infection for the intensivist. Intensive Care Med 2016;epublished May 12th
• Kapoor. Robotized surgical assistant in neurosurgery: Anaesthetic implications!. J Neuroanaesthesiol Crit Care 2016;3:151-2
• Bein. From Berlin to Kigali: the sobering journey of acute respiratory distress syndrome. J Thorac Dis 2016;8(5):E282-E284
• Thongprayoon. Serum creatinine level, a surrogate of muscle mass, predicts mortality in critically ill patients. J Thorac Dis 2016;8(5):E305-E311
• Tsirigotis. Balanced control of both hyper and hypo-inflammatory phases as a new treatment paradigm in sepsis. J Thorac Dis 2016;8(5):E312-E316

• Drazen. Data Sharing and the Journal. N Engl J Med 2016;374:e24

There is only one month to SMACC DUB. If you haven't yet booked your pre-conference workshop, then the "Stop Gambling - Applying Evidence to Practice" session comes highly recommended (...cough...). You will be encouraged to doubt the ground on which you stand, then come to terms with how we handle that uncertainty in real life practice – without becoming a nihilist.

The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.

A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day.  Book before 1st May to avail of the Early Bird option of €30 (limited availability).

Please contact Louise at lburke@ucd.ie to register for the meeting and meal.

The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. The meeting programme and registration are available on the brand new, and beautiful, Intensive Care Society of Ireland website.

The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.

• Abstract:  Walsh. Staff education, regular sedation and analgesia quality feedback, and a sedation monitoring technology for improving sedation and analgesia quality for critically ill, mechanically ventilated patients: a cluster randomised trial. Lancet Respir Med 2016;epublished July 26th
• Full Text:  Frazzitta. Effectiveness of a Very Early Stepping Verticalization Protocol in Severe Acquired Brain Injured Patients: A Randomized Pilot Study in ICU. PLoS ONE 2016;11(7):e0158030
• Abstract:  Wang. Association between chloride-rich versus chloride-restrictive intravenous fluid administration and acute kidney injury in cardiovascular patients in ICU wards. Exp Ther Med 2016;12(2):987-990
• Abstract:  Uranga. Duration of Antibiotic Treatment in Community-Acquired PneumoniaA Multicenter Randomized Clinical Trial. JAMA Intern Med 2016;epublished July 25th
• Full Text:  Dugernier. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study. Ann Intensive Care 2016;6(1):73

• Full Text:  Guo. Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis. Critical Care 2016;20:226
• Full Text:  Stevenson. Sepsis: the LightCycler SeptiFast Test MGRADE(R), SepsiTest and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi - a systematic review and economic evaluation. Health Technol Assess 2016;20(46):1-246
• Abstract:  Pettilä. Control groups in recent septic shock trials: a systematic review. Intensive Care Med 2016;epublished July 23rd
• Abstract:  Martins. Palliative care for terminally ill patients in the intensive care unit: Systematic review and metaanalysis. Palliat Support Care 2016;epublished July 27th
• Full Text:  Koster. Milrinone for cardiac dysfunction in critically ill adult patients: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. Intensive Care Med 2016;epublished July 22nd
• Abstract:  de Meirelles Almeida. Diastolic dysfunction as a predictor of weaning failure: A systematic review and meta-analysis. J Crit Care 2016;34:135-141
• Abstract:  Pettilä. Control groups in recent septic shock trials: a systematic review. Intensive Care Med 2016;epublished July 23rd

• Full Text:  Zakharchenko. The Effects of High Level Magnesium Dialysis/Substitution Fluid on Magnesium Homeostasis under Regional Citrate Anticoagulation in Critically Ill. PLoS One 2016;11(7):e0158179
• Abstract:  Zhu. Assessing Protocol Adherence in a Clinical Trial with Ordered Treatment Regimens: Quantifying the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial Experience. Injury 2016;epublished July 20th
• Abstract:  Brown. Predictors of 6-month health utility outcomes in survivors of acute respiratory distress syndrome. Thorax 2016;epublished July 20th
• Abstract:  Braune. The feasibility and safety of extracorporeal carbon dioxide removal to avoid intubation in patients with COPD unresponsive to noninvasive ventilation for acute hypercapnic respiratory failure (ECLAIR study): multicentre case–control study. Intensive Care Med 2016;epublished July 25th
• Abstract:  Kadri. Estimating Ten-Year Trends in Septic Shock Incidence and Mortality in United States Academic Medical Centers Using Clinical Data. Chest 2016;epublished July 28th
• Abstract:  Klouwenberg. Incidence, Predictors and Outcomes of New-onset Atrial Fibrillation in Critically Ill Patients with Sepsis: a Cohort Study. Am J Respir Crit Care Med 2016;epublished July 28th
• Full Text: Coupez. Guidewire exchange vs new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction? Critical Care 2016;20:230
• Abstract:  Ranzani. The Challenge of Predicting Pressure Ulcers in Critically Ill Patients: A Multicenter Cohort Study. Annals ATS 2016;epublished 27 July 2016
• Abstract:  Martin. ALIAS (Albumin in Acute Ischemic Stroke) Trials: Analysis of the Combined Data From Parts 1 and 2. Stroke 2016;epublished July 26th
• Abstract:  Hay. Characteristics and outcome of patients with the ICU Admission diagnosis of status epilepticus in Australia and New Zealand. J Crit Care 2016;34:146–153
• Abstract:  Salih. Intracranial pressure and cerebral perfusion pressure in patients developing brain death. J Crit Care 2016;34:1-6
• Abstract:  Delgado. Safety of peripheral administration of phenylephrine in a neurologic intensive care unit: A pilot study. J Crit Care 2016;34:107-110

• Guay. Epidural local anaesthetics versus opioid-based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery. Cochrane Database of Systematic Reviews 2016, Issue 7. Art. No.: CD001893

• Villar. Evaluating the efficacy of dexamethasone in the treatment of patients with persistent acute respiratory distress syndrome: study protocol for a randomized controlled trial. Trials 2016;17:342

Neurological                     

• Taito. Early mobilization of mechanically ventilated patients in the intensive care unit. Journal of Intensive Care 2016;4:50
• Disma. Pediatric anesthesia and neurotoxicity: can findings be translated from animals to humans? Minerva Anestesiologica 2016;82(7):791-6
• Eytan. Bedside functional brain imaging in critically-ill children using high-density EEG source modeling and multi-modal sensory stimulation. Neuroimage Clin 2016;12:198-211
• D'Andrea. Transcranial Doppler ultrasonography: From methodology to major clinical applications. World J Cardiol 2016;8(7):383-400

Circulatory

• Sen. Mechanical circulatory assist devices: a primer for critical care and emergency physicians. Critical Care 2016;20:153
• Mejía-Rentería. Takotsubo syndrome: Advances in the understanding and management of an enigmatic stress cardiomyopathy. World J Cardiol 2016;8(7):413-424
• Ryerson. Anticoagulation Management and Monitoring during Pediatric Extracorporeal Life Support: A Review of Current Issues. Front Pediatr 2016;4:67

Respiratory

• Filosso. When size matters: changing opinion in the management of pleural space—the rise of small-bore pleural catheters. J Thorac Dis 2016;8(7):E503-E510

Gastrointestinal

• Vickers. Ridinilazole: a novel therapy for Clostridium difficile infection. International Journal of Antimicrobial Agent 2016;48(2):137–143

Hepatobiliary

• Bolondi. Predictive factors of short term outcome after liver transplantation: A review. World J Gastroenterol 2016;22(26):5936-5949
• Donnelly. Role of inflammation and infection in the pathogenesis of human acute liver failure: Clinical implications for monitoring and therapy. World J Gastroenterol 2016;22(26):5958-5970
• Shayto. Use of rifaximin in gastrointestinal and liver diseases. World J Gastroenterol 2016;22(29):6638-6651
• Kasarala. Standard liver tests. Clinical Liver Disease 2016;8:13–18
• Volk. Patient-centered liver transplantation. Clinical Liver Disease 2016;8:24–27

Sepsis

• Beloncle. Mean arterial pressure target in patients with septic shock. Minerva Anestesiologica 2016;82(7):777-84
• Leligdowicz. Ebola virus disease and critical illness. Critical Care 2016;20:217
• Hidalgo. Ceftazidime/avibactam: a novel cephalosporin/nonbeta-lactam beta-lactamase inhibitor for the treatment of complicated urinary tract infections and complicated intra-abdominal infections. Drug Design, Development and Therapy 2016;10:2379—2386
• Nathwani. Early clinical assessment of response to treatment of skin and soft-tissue infections: how can it help clinicians? Perspectives from Europe. International Journal of Antimicrobial Agent 2016;48(2):127–136
• Nadel. Treatment of Meningococcal Disease. J Adolesc Health 2016;59(2 Suppl):S21-8

Trauma

• Kumar. Role of magnetic resonance imaging in acute spinal trauma: a pictorial review. BMC Musculoskeletal Disorders 2016;17:310

Toxicology

• Krishnamoorthy. The role of electroencephalography in the diagnosis of serotonin syndrome. JICS 2016;17(3):258-261
• Schuckit. Treatment of Opioid-Use Disorders. N Engl J Med 2016;375:357-368

Miscellaneous

• Warrillow. how to improve communication quality with patients and relatives in the ICU. Minerva Anestesiologica 2016;82(7):797-803 
• Szawarski. Classic cases revisited: Mr David James, futile interventions and conflict in the ICU. JICS 2016;17(3):244-251

• Wood. Wood and Trees do journal club. JICS 2016;17(3):273-274

• Blanch. Dead space in acute respiratory distress syndrome: more than a feeling! Critical Care 2016;20:214
• Cardinal-Fernández. ARDS: Time to “separate the wheat from the chaff”. J Crit Care 201;34:31-32
• Guerin. Assessment of oxygenation response to prone position ventilation in ARDS by lung ultrasonography. Intensive Care Med 2016;epublished July 22nd
• Rady. Neuroscience and awareness in the dying human brain: Implications for organ donation practices. J Crit Care 201;34:31-33
• Jones. Methadone in the critically ill—An unlikely player in intensive care medicine. J Crit Care 201;34:162

• Boyd. The future workforce of our Intensive Care Units – Doctor, physician assistant or no-one? JICS 2016;17(3):18-190

• Abbasi. Infectious Disease Expert Sees Threat From Colistin-Resistant Superbug. JAMA 2016;epublished July 27th
• Doyle. Goal-directed therapy and acute kidney injury: as good as it gets? Critical Care 2016;20:174

• Joyner. What Happens When Underperforming Big Ideas in Research Become Entrenched? JAMA 2016;epublished July 28th
• Williams. Composite Endpoints in Clinical Trials. The Scientist 2016;epublished July 1st

Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.

Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.

Following last year's massively successful event, the UK Intensive Care Society's State-of-the-Art Meeting is starting its build-up to 2016. The ICS completely changed its game in 2015, and relaunched SOA as a new beacon for forward-looking clinical content, open-access education, and medical social media. In keeping with the times, the podcasts and other materials from last year's meeting have been made open access.
 
This year the programme is looking even better, with topics ranging from the futuristic (space medicine, Formula 1 applied technology, Google Deepmind, and AI) through to the human, practical, and controversial (look out for the clinical scenarios, controversies, and the "From Ivory Tower to Desert Island" session).  Speakers include Peter Brindley, Kevin Fong, Jack Iwashyna, Kath Maitland, Louise Rose, Mervyn Singer, and Jean-Louis Vincent among many others.  It runs from Mon 5th - Wed 7th Dec, and I hope I'll see you there.  Keep an eye on http://soa.ics.ac.uk for programme and registration, and meanwhile enjoy the comprehensive FOAM from last year.

The 1st World Sepsis Congress will take place completely online on September 8th and 9th, 2016, as a prelude and introduction to the fifth World Sepsis Day on September 13th, 2016. Participation is open to everyone with an internet connection and free of charge. In 13 distinctive sessions, over 70 speakers from over 20 countries will give 10-minute keynotes and presentations on the number one preventable cause of death worldwide: sepsis. After each talk, the speakers will answer live questions from the audience.

Highlights include the Opening Session, titled "Sepsis - A Global Health Threat", with German Minister Helge Braun, Marie-Paule Kieny, Assistant Director-General of the WHO, Achim Steiner, former Under-Secretary General UN and Director of UNEP, and Joe Kiani, Founder & CEO of the Patient Safety Movement Foundation. To read the full invitation letter from the program chairs, Simon Finfer and Konrad Reinhart, please click here.

Register   |   Program  |   Sponsors

(Image from Chensiyuan via Wikipedia)

This adult and paediatric ICM meeting is jointly organized by the Society of Intensive Care Medicine (SICM), Singapore and the Australia-New Zealand Intensive Care Society (ANZICS) and is scheduled for 20-24 April 2017 in Suntec Convention Centre, Singapore. It has grown from its humble beginnings in a small hospital venue to become one of the best ICM conference in the Asia-Pacific region. Past editions featured prominent speakers such as Jean Louis Vincent, Daniel De Backer, John J Marini, Rinaldo Bellomo amongst many others, and in this edition the list of distinguished international panel of speakers, program schedule and planned workshops look more impressive than ever. Beside the obvious educational benefits, this conference is also a great opportunity to experience the unique Singaporean culture, enjoy its famed gastronomy and visit its attractions. Registration is yet to open so do subscribe to its newsletter at www.sg-anzics.com for updates.

• Full Text:  Hutchinson. Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension (RESCUEicp). N Engl J Med 2016;epublished September 7th
  
  • Editorial:  Shutter. Intracranial Pressure Rescued by Decompressive Surgery after Traumatic Brain Injury. N Engl J Med 2016;epublished September 7th
• Full Text:  Abdalla. A comparative study between terlipressin alone and dobutamine and terlipressin in septic shock patients. Ain-Shams J Anaesthesiol 2016;9:330-6
• Abstract:  Jabaudon. Sevoflurane for Sedation in ARDS: A Randomized Controlled Pilot Study. Am J Respir Crit Care Med 2016;epublished September 9th
• Abstract:  Kelly. Haemodynamic effects of parenteral vs. enteral paracetamol in critically ill patients: a randomised controlled trial. Anaesthesia 2016;71(10):1153-1162
• Abstract:  Wallentin. Early invasive versus non-invasive treatment in patients with non-ST-elevation acute coronary syndrome (FRISC-II): 15 year follow-up of a prospective, randomised, multicentre study. Lancet 2016;epublished August 25th

• Abstract:  Huang. Intravenous immunoglobulin for the treatment of toxic epidermal necrolysis: a systematic review and meta-analysis. Giornale Italiano di Dermatologia e Venereologia 2016;151(5):515-24
• Abstract:  Laina. Amiodarone and cardiac arrest: Systematic review and meta-analysis. International Journal of Cardiology 2016;221(15):780-788
• Full Text:  Tan. Vasopressin and its analog terlipressin versus norepinephrine in the treatment of septic shock: a meta-analysis. Int J Clin Exp Med 2016;9(7):14183-14190

• Full Text:  Colson. Active Bleeding after Cardiac Surgery: A Prospective Observational Multicenter Study. PLoS One 2016;11(9):e0162396
• Full Text:  Gershengorn. Association Between Overnight Extubations and Outcomes in the Intensive Care Unit. JAMA Intern Med 2016;epublished September 6th
• Full Text:  Rochwerg. Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study. Can Respir J 2016;2016:8671742
• Abstract:  Deakin. Effects of epinephrine on cerebral oxygenation during cardiopulmonary resuscitation: A prospective cohort study. Resuscitation 2016;epublished August 31st
• Full Text:  Bihari. Maintenance fluid practices in intensive care units in Australia and New Zealand. Crit Care Resusc 2016;18(2):89-94
• Full Text:  Kasenda. Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS. BMJ Open 2016;6(9):e011148
• Full Text:  Shahin. Predicting invasive fungal disease due to Candida species in non-neutropenic, critically ill, adult patients in United Kingdom critical care units. BMC Infectious Diseases 2016;16:480

• Kakkos. Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism. Cochrane Database of Systematic Reviews 2016, Issue 9. Art. No.: CD005258

• Allingstrup. Early goal-directed nutrition in ICU patients (EAT-ICU): protocol for a randomised trial. Dan Med J 2016;63(9):A5271

Neurological

• Dholke. Cerebral salt wasting syndrome. J Neuroanaesthesiol Crit Care 2016;3:205-10
• Abraham. Perioperative management of patients with pituitary tumours. J Neuroanaesthesiol Crit Care 2016;3:211-8
• Bindu. Anaesthesia and deep brain stimulation. J Neuroanaesthesiol Crit Care 2016;3:197-204

Circulatory

• Boyd. Echocardiography as a guide for fluid management. Critical Care 2016;20:274
• Martin. The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in Sepsis. BioMed Research International 2016;2016:3758278
• Ushiyama. Glycocalyx and its involvement in clinical pathophysiologies. Journal of Intensive Care 2016;4:59
• Magder. Volume and its relationship to cardiac output and venous return. Critical Care 2016;20:271
• Walley. Left ventricular function: time-varying elastance and left ventricular aortic coupling. Critical Care 2016;20:270
• Pinsky. The right ventricle: interaction with the pulmonary circulation. Critical Care 2016;20:266
• Halkar. Dual antiplatelet therapy for acute coronary syndromes: How long to continue? CCJM 2016;83(9):675-688
• Meineri. Transesophageal echocardiography: what the anesthesiologist has to know. Minerva Anestesiologica 2016;82(8):895-907

Respiratory

• Hew. The efficacy of bedside chest ultrasound: from accuracy to outcomes. European Respiratory Review 2016;25:230-246
• Lee. Lung ultrasound-a primary survey of the acutely dyspneic patient. J Intensive Care 2016;31;4(1):57
• George. An emerging interstitial lung disease. Lancet Respir Dis 2016;4(9):762  (free registration required)
• Beck. Neurally-adjusted ventilatory assist (NAVA) in children: a systematic review. Minerva Anestesiologica 2016;82(8):874-83

Hepatobiliary

•  Robles-Díaz. Biomarkers in DILI: One More Step Forward. Front Pharmacol 2016;epublished August 22nd

Endocrine

• Langsang. Inpatient hyperglycemia management: A practical review for primary medical and surgical teams. CCJM 2016 May;83 Suppl 1(5):S34-S43

Haematological

• Vargas. Bleeding management in patients with new oral anticoagulants. Minerva Anestesiologica 2016;82(8):884-94

Sepsis

• Patel. New Developments in Clinical Bacteriology Laboratories. Mayo Clin Proc 2016;epublished August 20th

• Hazra. Biostatistics series module 5: Determining sample size. Indian J Dermatol 2016;61:496-504
• Setia. Methodology series module 5: Sampling strategies. Indian J Dermatol 2016;61:505-9

Chest

Reviews

• Paikin. Timing the First Postoperative Dose of Anticoagulants: Lessons Learned From Clinical Trials. Chest 2015;148(3):587-595
• Jecker. Ebola Virus Disease: Ethics and Emergency Medical Response Policy. Chest 2015;148(3):794-800
• Sinha. CPAP and High-Flow Nasal Cannula Oxygen in Bronchiolitis. Chest 2015;148(3):810-823

Case Reports

• Blanco. A 43-Year-Old Man Presenting With Severe Chest Pain. Chest 2015;148(3):e76-e79

Anesthesiology

Reviews

• Kalkman. Survival after Perioperative Cardiopulmonary Resuscitation: Providing an Evidence Base for Ethical Management of Do-not-resuscitate Orders. Anesthesiology 2016;124:723-729

Case Reports

• Serdiuk. An Unexpected Embolism during a Craniotomy. Anesthesiology 2016;124:721
• Munoz. Severe Bilateral Ocular Hypotony after Emergent Coronary Artery Bypass Graft Surgery Complicated with Cardiogenic Shock. Anesthesiology 2016;124:72

Anesthesia & Analgesia

Reviews

• Tousignant. Pulmonary Impedance and Pulmonary Doppler Trace in the Perioperative Period. Anesth Analg 2015;121(3):601-609
• Crystal. Carbon Dioxide and the Heart: Physiology and Clinical Implications. Anesth Analg 2015;121(3):610-623
• Murray. Ebola Virus Disease: A Review of Its Past and Present. Anesth Analg 2015;121(3):798-809
• Missair. Anesthetic Implications of Ebola Patient Management: A Review of the Literature and Policies. Anesth Analg 2015;121(3):810-821

Commentary

• Kempen. A Tale of Silent Aspiration: Are Guidelines Good for Every Patient? Anesth Analg 2015;121(3):829-831

British Journal of Anaesthesia

Editorials

• Sear. Beta-blockade and other perioperative pharmacological protectors: what is now available and efficacious? Br J Anaesth 2015;115(3):333-336
• Gibbs. Misuse of ‘trend’ to describe ‘almost significant’ differences in anaesthesia research. Br J Anaesth 2015;115(3):337-339
• Giambrone. Information technology innovation: the power and perils of big data. Br J Anaesth 2015;115(3):339-342
• Devinney. Climbing the delirium mountain: is alpine anaesthesia the perioperative cause? Br J Anaesth 2015;115(3):342-344
• Pryor. The elusive promise of perioperative hyperoxia. Br J Anaesth 2015;115(3):344-346
• Marik. Fluid therapy in 2015 and beyond: the mini-fluid challenge and mini-fluid bolus approach. Br J Anaesth 2015;115(3):347-349

Reviews

• Simpao. Big data and visual analytics in anaesthesia and health care. Br J Anaesth 2015;115(3):350-356 
• De Santis. Tissue oxygen tension monitoring of organ perfusion: rationale, methodologies, and literature review. Br J Anaesth 2015;115(3):357-365
• Moore. Microcirculatory dysfunction and resuscitation: why, when, and how. Br J Anaesth 2015;115(3):366-375

Anaesthesia

Editorials

• Sear. Beta-blockade and other perioperative pharmacological protectors: what is now available and efficacious? Br J Anaesth 2015;115(3):333-336
• Gibbs. Misuse of ‘trend’ to describe ‘almost significant’ differences in anaesthesia research. Br J Anaesth 2015;115(3):337-339
• Giambrone. Information technology innovation: the power and perils of big data. Br J Anaesth 2015;115(3):339-342
• Devinney. Climbing the delirium mountain: is alpine anaesthesia the perioperative cause? Br J Anaesth 2015;115(3):342-344
• Pryor. The elusive promise of perioperative hyperoxia. Br J Anaesth 2015;115(3):344-346
• Marik. Fluid therapy in 2015 and beyond: the mini-fluid challenge and mini-fluid bolus approach. Br J Anaesth 2015;115(3):347-349

Reviews

• Simpao. Big data and visual analytics in anaesthesia and health care. Br J Anaesth 2015;115(3):350-356
• De Santis. Tissue oxygen tension monitoring of organ perfusion: rationale, methodologies, and literature review. Br J Anaesth 2015;115(3):357-365
• Moore. Microcirculatory dysfunction and resuscitation: why, when, and how. Br J Anaesth 2015;115(3):366-375

Minerva Anesthesiologica

Reviews

• Girardis. A critical appraisal of the quality of analgosedation guidelines in critically ill patients. Minerva Anestesiologica 2016;82(2):230-5
• Massimo. Could “safe practice” be compromising safe practice? Should anesthetists have to deflate the cuff of the endotracheal tube before extubation? Minerva Anestesiologica 2016;82(2):236-9

Anaesthesia

Editorial

• McCombe. Paternalism and consent: has the law finally caught up with the profession?. Anaesthesia 2015;70:1016–1019

Respiratory Care

Reviews

• Verceles. Use of Accelerometry to Monitor Physical Activity in Critically Ill Subjects: A Systematic Review. Respir Care 2015;60(9):1330-1336

Medicina Intensiva

Reviews

• Álvarez-Fernández. Clinical ultrasound in the ICU: Changing a medical paradigm. Med Intensiva 2016;40:246-9

Critical Care & Resuscitation

Editorials

• Darvall. Shedding (infrared) light on the septic brain. Crit Care Resusc 2016;18(2):67-68

Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.

Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.

Following last year's massively successful event, the UK Intensive Care Society's State-of-the-Art Meeting is starting its build-up to 2016. The ICS completely changed its game in 2015, and relaunched SOA as a new beacon for forward-looking clinical content, open-access education, and medical social media. In keeping with the times, the podcasts and other materials from last year's meeting have been made open access.
 
This year the programme is looking even better, with topics ranging from the futuristic (space medicine, Formula 1 applied technology, Google Deepmind, and AI) through to the human, practical, and controversial (look out for the clinical scenarios, controversies, and the "From Ivory Tower to Desert Island" session).  Speakers include Peter Brindley, Kevin Fong, Jack Iwashyna, Kath Maitland, Louise Rose, Mervyn Singer, and Jean-Louis Vincent among many others.  It runs from Mon 5th - Wed 7th Dec, and I hope I'll see you there.  Keep an eye on http://soa.ics.ac.uk for programme and registration, and meanwhile enjoy the comprehensive FOAM from last year.

(Image from Chensiyuan via Wikipedia)

This adult and paediatric ICM meeting is jointly organized by the Society of Intensive Care Medicine (SICM), Singapore and the Australia-New Zealand Intensive Care Society (ANZICS) and is scheduled for 20-24 April 2017 in Suntec Convention Centre, Singapore. It has grown from its humble beginnings in a small hospital venue to become one of the best ICM conference in the Asia-Pacific region. Past editions featured prominent speakers such as Jean Louis Vincent, Daniel De Backer, John J Marini, Rinaldo Bellomo amongst many others, and in this edition the list of distinguished international panel of speakers, program schedule and planned workshops look more impressive than ever. Beside the obvious educational benefits, this conference is also a great opportunity to experience the unique Singaporean culture, enjoy its famed gastronomy and visit its attractions. 

Registration is yet to open so do subscribe to its newsletter at www.sg-anzics.com for updates.

• Full Text:  Hofmann. Oxygen Therapy in Suspected Acute Myocardial Infarction (DETO2X–SWEDEHEART). N Engl J Med 2017;epublished August 28th
  
  • Editorial:  Loscalzo. Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer. N Engl J Med 2017;epublished August 28th
• Full Text:  Ridker. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med 2017;epublished August 27th
  
  • Editorial:  Harrington. Targeting Inflammation in Coronary Artery Disease. N Engl J Med 2017;epublished August 27th
• Full Text:  Litton. Quality sleep using earplugs in the intensive care unit: the QUIET pilot randomised controlled trial. Crit Care Resus 2017;19(2):128-133
• Abstract:  Stöckl. Continuous versus intermittent neuromuscular blockade in patients during targeted temperature management after resuscitation from cardiac arrest - A randomized, double blinded, double dummy, clinical trial. Resuscitation 2017;epublished August 28th
• Abstract:  El-Kersh. Enteral nutrition as stress ulcer prophylaxis in critically ill patients: A randomized controlled exploratory study. J Crit Care 2017;epublished August 26th
• Full Text:  Pu. Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment-Elevation Myocardial Infarction: EARLY-MYO Trial (Early Routine Catheterization After Alteplase Fibrinolysis Versus Primary PCI in Acute ST-Segment-Elevation Myocardial Infarction). Circulation 2017;epublished August 27th
  • Editorial:  Armstrong. Recalibrating Reperfusion Waypoints. Circulation 2017;epublished August 27th
• Abstract:  Weinberg. Effects of intraoperative and early postoperative normal saline or Plasma-Lyte 148® on hyperkalaemia in deceased donor renal transplantation: a double-blind randomized trial. Br J Anaesth 2017;epublished August 30th 
• Abstract:  de la Gala. Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia. Br J Anaesth 2017;epublished August 30th
• Abstract:  Göcze. Biomarker-guided Intervention to Prevent Acute Kidney Injury After Major Surgery: The Prospective Randomized BigpAK Study. Ann Surg 2017;epublished August 29th

• Full Text:  Davies. Protein delivery and clinical outcomes in the critically ill: a systematic review and meta-analysis. Crit Care Resus 2017;19(2):117-127
• Full Text:  Serpa Neto. Balanced versus isotonic saline resuscitation-a systematic review and meta-analysis of randomized controlled trials in operation rooms and intensive care units. Ann Transl Med 2017;(16):323
• Abstract:   Lewis. Videolaryngoscopy versus direct laryngoscopy for adult patients requiring tracheal intubation: a Cochrane Systematic Review. Br J Anaesth 2017;epublished August 30th
• Abstract:   Walkey. Low Tidal Volume versus Non-Volume-Limited Strategies for Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis. Ann Am Thorac Soc 2017;epublished August 28th
• Abstract:  Tsivgoulis. Noninvasive Ventilatory Correction in Patients With Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Stroke 2017;48(8):2285-2288
• Abstract:  Duyx. Scientific citations favor positive results: a systematic review and meta-analysis. Journal of Clinical Epidemiology 2017;88:92-101
• Abstract:  Dupont. Antifungal Prevention of Systemic Candidiasis in Immunocompetent ICU Adults: Systematic Review and Meta-Analysis of Clinical Trials. Crit Care Med 2017;epublished August 28th
• Abstract:  van de Weerdt. Central venous catheter placement in coagulopathic patients: risk factors and incidence of bleeding complications. Transfusion 2017;epublished August 30th
• Abstract:  Chowdhury. Antiarrhythmics in Cardiac Arrest: A Systematic Review and Meta-Analysis. Heart Lung Circ 2017;epublished August 22nd

• Abstract:  Jolley. Relationship between Race and the Effect of Fluids on Long-term Mortality after Acute Respiratory Distress Syndrome. Secondary Analysis of the National Heart, Lung, and Blood Institute Fluid and Catheter Treatment Trial. Annals ATS 2017;14(9):1443–1449
• Abstract:  Haas. Descriptive analysis of extracorporeal cardiopulmonary resuscitation following out-of-hospital cardiac arrest—An ELSO registry study. Resuscitation 2017;119:56–62
• Abstract:  Moseby-Knappe. Head computed tomography for prognostication of poor outcome in comatose patients after cardiac arrest and targeted temperature management. Resuscitation 2017;119:89–94
• Abstract:  Huis in 't Veld. Ultrasound use during cardiopulmonary resuscitation is associated with delays in chest compressions. Resuscitation 2017;119:95–98
• Abstract:  Biais. Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room. Anesthesiology 2017;127(3):450-456
• Abstract:  Perneger. The distribution of P-values in medical research articles suggested selective reporting associated with statistical significance. Volume Journal of Clinical Epidemiology 2017;87:70-77
• Abstract: Stelfox. A multi-center prospective cohort study of patient transfers from the intensive care unit to the hospital ward. Intensive Care Med 2017;epublished August 29th
• Abstract: Faguer. Heparin-Free Prolonged Intermittent Hemodialysis Using Calcium-Free Citrate Dialysate in Critically Ill Patients. Crit Care Med 2017;epublished August 28th
• Full Text:  Bennett. Functional Outcome After Intracranial Pressure Monitoring for Children With Severe Traumatic Brain Injury. JAMA Pediatr 2017;epublished August 28th
  • Editorial:  Horvat. Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury. JAMA Pediatr 2018;epublished August 28th
• Abstract:  Fisher. Balanced haemostasis with both hypo- and hyper-coagulable features in critically ill patients with acute-on-chronic-liver failure. J Crit Care 2017;43:54-60

• Billot. Statistical analysis plan for the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock (ADRENAL) trial. Crit Care Resus 2017;19(2):183-191
  • Appendix
• Macdonald. REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial. Trials 2017;18:399
• Zampieri. Study protocol for the Balanced Solution versus Saline in Intensive Care Study (BaSICS): a factorial randomised trial. Crit Care Resus 2017;19(2):175-182
  
  • Appendix
• Huang. Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection. BMC Emergency Medicine 2017;17:25
• Da Collina. Oral hygiene in intensive care unit patients with photodynamic therapy: study protocol for randomised controlled trial. Trials 2017;18:385

Neurological

• Udy. Critical care management of aneurysmal subarachnoid haemorrhage in Australia and New Zealand: what are we doing, and where to from here? Crit Care Resus 2017;19(2):103-109

Circulatory

• Liu. Sepsis-Induced Cardiomyopathy: Mechanisms and Treatments. Front Immunol 2017;8:1021
• Zochios. The Right Ventricle in ARDS. Chest 2017;152(1):181-193
• Rymer. Failure to Launch : Targeting Inflammation in Acute Coronary Syndromes. J Am Coll Cardiol Basic Trans Science 2017;2:484
• Saugel. Ultrasound-guided central venous catheter placement: a structured review and recommendations for clinical practice. Critical Care 2017;21:225
• Miller. Computed Tomography Angiographic Assessment of Acute Chest Pain. Journal of Thoracic Imaging 2017;32(3):137–150
• Latson. Imaging of the Postsurgical Thoracic Aorta: A State-of-the-Art Review. Journal of Thoracic Imaging 2017;32(1):1–25
• Martin. Pathophysiology, diagnosis and treatment of tachycardiomyopathy. Heart 2017;epublished August 30th

Respiratory

• Siddiqui. Three decades of transtracheal oxygen therapy: A review of the associated complications with an illustrative case presentation. Lung India 2017;34:448-51
• Akca. WHO Needs High FIO₂? Turk J Anaesthesiol Reanim 2017; 45: 181-92

Gastrointestinal

• Evans. Pancreatitis: Preventing catastrophic haemorrhage. World J Gastroenterol 2017;23(30):5460-5468

Hepatobiliary

•  Alexopoulou. Bacterial translocation markers in liver cirrhosis. Ann Gastroenterol 2017;30(5):486-497

 Renal

• Jaswani. MicroRNAs involvement in renal pathophysiology: A bird's eye view. Indian J Nephrol 2017;27:337-41

Haematological

• Pyropoulos. New paradigms in venous thromboprophylaxis of medically ill patients. Thromb Haemost 2017;117:1662–1670

Sepsis

• Laroye. Mesenchymal Stromal/Stem Cells: A New Treatment For Sepsis And Septic Shock? Stem Cells 2017;epublished August 30th
• Wiederhold. Antifungal resistance: current trends and future strategies to combat. Infection and Drug Resistance 2017;10:249—259

• Zuidgeesta. Series: Pragmatic trials and real world evidence: Paper 1. Introduction. Journal of Clinical Epidemiology 2017;88:7-13
• Worsley. Series: Pragmatic trials and real world evidence: Paper 2. Setting, sites, and investigator selection. Journal of Clinical Epidemiology 2017;88:14-20
• Streetera. Adjusting for unmeasured confounding in nonrandomized longitudinal studies: a methodological review. Journal of Clinical Epidemiology 2017;88:23-34
• Rucker. Flipped classroom model for learning evidence-based medicine. Advances in Medical Education and Practice 2017;8:619—625

• Chertoff. A 45-Year-Old Woman with Acute Interstitial Pneumonia (Hamman–Rich Syndrome). Turk J Anaesthesiol Reanim 2017; 45: 244Turk J Anaesthesiol Reanim 2017; 45: 244

• Kaestner. Conflicts of interest in Twitter. Lancet Haematology 2017;4(9):e408–e409
• Meroni. Biomarkers in acute kidney injury: that’s all the story? Intensive Care Med 2017;epublished August 29th

• Bag-mask ventilation vs endotracheal intubation in out-of-hospital cardiac arrest (CAAM Trial) - presented at the European Society of Cardiology Congress in Barcelona August 28th

It's now just 4 months until the Critical Care Reviews Meeting 2018, where the chief investigators for the best critical care trials of 2017 come to discuss their work and try to answer the question clinicians want to know - should I change my practice based on this trial? From Brisbane, Australia, Prof Bala Ventakesh will explore the ADRENAL trial, examining hydrocortisone in septic shock in the biggest sepsis trial ever undertaken. Working between Dublin and Melbourne, Prof Alistair Nichol will explain the findings of the TRANSFUSE trial, comparing transfusion of the freshest available blood with standard issued red cells. From Nantes, France, Dr Jean-Baptiste Lascarrou will consider the findings of the MACMAN trial, evaluating video laryngoscopy in the ICU. Dr Ashish Khanna, from the Cleveland Clinic, USA, will reflect on ATHOS-3 the first large clinical trial examining angiotensin II in septic shock. Prof Gavin Perkins, from Warwick in England, will discuss his multi-centre randomized controlled trial Breathe, evaluating the role of extubation to non-invasive ventilation in patients failing spontaneous breathing trials. Prof John Simpson, from Newcastle, England, will discuss the VAP-RAPID trial, evaluating the use of a biomarker-guided approach to exclude ventilator-associated pneumonia. We also have Prof Andrew Rhodes from London, exploring the latest iteration of the Surviving Sepsis Campaign, published earlier this year, and Dr Sophie Wallace (Perth, Australia), who will deliver the honorary John Hinds Trauma Lecture, entitled "Disaster on Everest - Trauma at the Top of the World".

There is still an announcement or two to come, so watch this space!

We sold out #CCR17 and had to turn people away. At present we are way up on registrations compared to the same time-point in 2016. So, if you intend on coming, don't leave it too late to register. There is plenty of space still at present, but I expect the meeting will sell out well before it's date of Friday January 19th. Don't worry if you can't make it, as the talks will be recorded and put online for free viewing as usual. However, there is nothing like being there in person and having the opportunity to chat with these chief investigators. Numbers are strictly limited to ensure this remains a small, intimate meeting. It would be a shame to miss out......

The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.

The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring.  A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.

Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.

#BMBTL17 is a conference  on resuscitation that focuses on the skills and knowledge needed to bring your critically ill patients…back to life !

With cutting edge topics and a world class faculty, the conferences will be packed with clinical pearls and only the stuff that matters !

Ventilation, airway, EKGs, pediatric pearls, ultrasound and so much more…don’t miss this amazing conference ! It will be held on October 16th 2017 in downtown Montreal.

www.BringMeBackToLIFE.ca

FemInEM.org is excited to bring you our first ever, in person conference, FIX2017! The FemInEM Idea Exchange is all about education, inspiration and motivation.  Our world renowned faculty will speak from their hearts and minds, providing the substance and spark for you to change the world. We will meet, greet and motivate each other, pushing the limits of our previous selves.  You won't want to miss it - October 4th to 6th, NYC.

State-of-the-Art is back, for the 3rd year of its new format and an all-new venue in Liverpool for 2017. The futurism and innovation theme continues with novel topics including robotics, optical imaging of bacterial infection, new technology in patient recovery, and new device interventions in acute cardiology.  

However, the focus on day-to-day care is not lost, and there are clinical updates in acute medicine, ARDS, mechanical ventilation, trauma, nutrition, rehabilitation, endocrine management in ICU,  cancer patients in ICU, the difficult and altered airway, and much more.  Pragmatic "how I treat..." sessions proved popular last year and will continue, along with meaningful debates on UK critical care, including the trend toward centralisation.  

In addition, the trademark vibe of SOA will still be there with pop-up talks, panel debates, 'meet the expert' booths, new generation video e-posters, parent and infant facilities, two drinks evenings, and a new final night after-party.  Registration and abstract submission is now open at http://soa.ics.ac.uk.

We are very pleased to announce the 6th International Fluid Academy Days (iFAD), which will take place on November 23-25th 2017 at the Hilton Hotel in Antwerp, Belgium. The iFAD is an innovative Critical Care Educational meeting in true SMACC spirit. This conference provides the highest quality of Critical Care education and is guaranteed to innovate and inspire. Recent advances in fluid management, and hemodynamic and organ function monitoring in the critical care setting will be reviewed in a comprehensive manner for intensivists, anaesthesiologists and emergency physicians as well as interested internists and surgeons.

The iFAD Faculty is the most provocative, engaging, motivating and inspiring group of international educational speakers and as organizing committee we want to ensure we have the participants, sponsors and endorsers to match. Together, we make iFAD stand apart from other Critical Care conferences.

• Full Text:  Janz. A multicenter, randomized trial of a checklist for endotracheal intubation of critically ill adults (Check-UP Trial). Chest 2017;epublished September 13th
• Abstract:  Hassan. Nebulized Versus IV Amikacin as Adjunctive Antibiotic for Hospital and Ventilator-Acquired Pneumonia Postcardiac Surgeries: A Randomized Controlled Trial. Crit Care Med 2017;epublished August 28th
• Abstract:  Palmieri. Transfusion Requirement in Burn Care Evaluation (TRIBE): A Multicenter Randomized Prospective Trial of Blood Transfusion in Major Burn Injury. Annals of Surgery 2017;266(4):595-602
• Abstract:  Logallo. Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial. Lancet Neurology 2017;16(10):781–788
• Abstract:  Delorme. Effects of High-Flow Nasal Cannula on the Work of Breathing in Patients Recovering From Acute Respiratory Failure. Crit Care Med 2017;epublished August 28th
• Abstract:  Glumac. Effects of dexamethasone on early cognitive decline after cardiac surgery: A randomised controlled trial. Eur J Anaesth 2017;epublished May 18th
• Full Text:  Liu. The influence of analgesic-based sedation protocols on delirium and outcomes in critically ill patients: A randomized controlled trial. PLoS One 2017;12(9):e0184310

• Abstract:  Ng. Effect of nicotine replacement therapy on mortality, delirium, and duration of therapy in critically ill smokers: a systematic review and meta-analysis. Anaesth Intensive Care 2017;45(5):556-561
• Abstract:  Liu. Effect of simvastatin in patients with aneurysmal subarachnoid hemorrhage: A systematic review and meta-analysis. Am J Emerg Med 2017;epublished September 5th
• Abstract:  Pavasini. Extracorporeal Circulatory Support in Acute Coronary Syndromes: A Systematic Review and Meta-Analysis. Crit Care Med 2017;epublished August 24th
• Abstract:  Dupont. Antifungal Prevention of Systemic Candidiasis in Immunocompetent ICU Adults: Systematic Review and Meta-Analysis of Clinical Trials. Crit Care Med 2017;epublished August 28th
• Abstract:  Trauer. Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching. Crit Care Med 2017;epublished August 9th
• Abstract:  Goldfarb. Outcomes of Patient- and Family-Centered Care Interventions in the ICU: A Systematic Review and Meta-Analysis. Crit Care Med 2017;epublished July 26th
• Abstract:  Meade. Severity of Hypoxemia and Effect of High-Frequency Oscillatory Ventilation in Acute Respiratory Distress Syndrome. Am J Resp Crit Care Med 2017;196(6):727-733
• Abstract:  Yao. Enteral versus parenteral nutrition in critically ill patients with severe pancreatitis: a meta-analysis. Eur J Clin Nutr 2017;epublished September 13th
• Abstract:  Simon. Outcomes of restrictive versus liberal transfusion strategies in older adults from nine randomised controlled trials: a systematic review and meta-analysis. Lancet Haematology 2017;epublished September 11th

• Full Text:  Rhee. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA 2017;epublished September 13th
  • Editorial:  Rudd. Counting Sepsis, an Imprecise but Improving Science. JAMA 2017;epublished September 13th
• Abstract:  Debaty. Long-Term Prognostic Value of Gasping During Out-of-Hospital Cardiac Arrest. Journal of the American College of Cardiology 2017;70(12):
• Full Text:  Caironi. Circulating Biologically Active Adrenomedullin (bio-ADM) Predicts Hemodynamic Support Requirement and Mortality During Sepsis. Chest 2017;152(2):312-320
• Abstract:  Salih. Intracranial pressure and cerebral perfusion pressure in patients developing brain death. J Crit Care 2016;34:1-6
• Full Text:  Chan. Association of Trial Registration With Reporting of Primary Outcomes in Protocols and Publications. JAMA 2017;epublished September 11th
• Abstract:  Chan. Are physical measures related to patient-centred outcomes in ARDS survivors? Thorax 2017;72:884-892
• Abstract:  Uhl. Laboratory predictors of bleeding and the effect of platelet and RBC transfusions on bleeding outcomes in the PLADO trial. Blood 2017;130:1247
• Abstract:  Dupuis. Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model. Crit Care Med 2017;epublished September 12th
• Abstract:  Faguer. Heparin-Free Prolonged Intermittent Hemodialysis Using Calcium-Free Citrate Dialysate in Critically Ill Patients. Crit Care Med 2017;epublished August 28th
• Abstract:  Kentish-Barnes. "It Was the Only Thing I Could Hold Onto, But....": Receiving a Letter of Condolence After Loss of a Loved One in the ICU: A Qualitative Study of Bereaved Relatives' Experience. Crit Care Med 2017;epublished August 28th
• Abstract:  Duan. Management of ARDS and Refractory Hypoxemia: A Multicenter Observational Study. Ann Am Thorac Soc 2017;epublished September 14th
• Abstract:  Soltész. The effect of neuromuscular blockade on the efficiency of facemask ventilation in patients difficult to facemask ventilate: a prospective trial. Anaesthesia 2017;epublished September 14th
• Abstract:  Sjövall. Maximally effective dosing regimens of meropenem in patients with septic shock. Journal of Antimicrobial Chemotherapy 2017;epublished September 12th
• Abstract:  Kamdar. Return to work and lost earnings after acute respiratory distress syndrome: a 5-year prospective, longitudinal study of long-term survivors. Thorax 2017;epublished September 16th

• Gillies. Heat and moisture exchangers versus heated humidifiers for mechanically ventilated adults and children. Cochrane Database of Systematic Reviews 2017, Issue 9. Art. No.: CD004711

• Márta. High versus low energy administration in the early phase of acute pancreatitis (GOULASH trial): protocol of a multicentre randomised double-blind clinical trial. BMJ Open 2017;7:e015874

It's now just 4 months until the Critical Care Reviews Meeting 2018, where the chief investigators for the best critical care trials of 2017 come to discuss their work and try to answer the question clinicians want to know - should I change my practice based on this trial? From Brisbane, Australia, Prof Bala Ventakesh will explore the ADRENAL trial, examining hydrocortisone in septic shock in the biggest sepsis trial ever undertaken. Working between Dublin and Melbourne, Prof Alistair Nichol will explain the findings of the TRANSFUSE trial, comparing transfusion of the freshest available blood with standard issued red cells. From Nantes, France, Dr Jean-Baptiste Lascarrou will consider the findings of the MACMAN trial, evaluating video laryngoscopy in the ICU. Dr Ashish Khanna, from the Cleveland Clinic, USA, will reflect on ATHOS-3 the first large clinical trial examining angiotensin II in septic shock. Prof Gavin Perkins, from Warwick in England, will discuss his multi-centre randomized controlled trial Breathe, evaluating the role of extubation to non-invasive ventilation in patients failing spontaneous breathing trials. Prof John Simpson, from Newcastle, England, will discuss the VAP-RAPID trial, evaluating the use of a biomarker-guided approach to exclude ventilator-associated pneumonia. The final trial added to the programme is the ART Trial. Prof Alexandre Biasi Cavalcanti (São Paulo) will explain this Brazilian investigation testing alveolar recruitment in ARDS.

We also have Prof Andrew Rhodes, from London, exploring the latest iteration of the Surviving Sepsis Campaign, published earlier this year and Dr Sophie Wallace (Perth, Australia), who will deliver the honorary John Hinds Trauma Lecture, entitled "Disaster on Everest - Trauma at the Top of the World"

We sold out #CCR17 and had to turn people away. At present we are way up on registrations compared to the same time-point in 2016. So, if you intend on coming, don't leave it too late to register. There is plenty of space still at present, but I expect the meeting will sell out well before it's date of Friday January 19th. Don't worry if you can't make it, as the talks will be recorded and put online for free viewing as usual. However, there is nothing like being there in person and having the opportunity to chat with these chief investigators. Numbers are strictly limited to ensure this remains a small, intimate meeting. It would be a shame to miss out......

The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.

The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring.  A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.

Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.

#BMBTL17 is a conference  on resuscitation that focuses on the skills and knowledge needed to bring your critically ill patients…back to life !

With cutting edge topics and a world class faculty, the conferences will be packed with clinical pearls and only the stuff that matters !

Ventilation, airway, EKGs, pediatric pearls, ultrasound and so much more…don’t miss this amazing conference ! It will be held on October 16th 2017 in downtown Montreal.

www.BringMeBackToLIFE.ca

FemInEM.org is excited to bring you our first ever, in person conference, FIX2017! The FemInEM Idea Exchange is all about education, inspiration and motivation.  Our world renowned faculty will speak from their hearts and minds, providing the substance and spark for you to change the world. We will meet, greet and motivate each other, pushing the limits of our previous selves.  You won't want to miss it - October 4th to 6th, NYC.

State-of-the-Art is back, for the 3rd year of its new format and an all-new venue in Liverpool for 2017. The futurism and innovation theme continues with novel topics including robotics, optical imaging of bacterial infection, new technology in patient recovery, and new device interventions in acute cardiology.  

However, the focus on day-to-day care is not lost, and there are clinical updates in acute medicine, ARDS, mechanical ventilation, trauma, nutrition, rehabilitation, endocrine management in ICU,  cancer patients in ICU, the difficult and altered airway, and much more.  Pragmatic "how I treat..." sessions proved popular last year and will continue, along with meaningful debates on UK critical care, including the trend toward centralisation.  

In addition, the trademark vibe of SOA will still be there with pop-up talks, panel debates, 'meet the expert' booths, new generation video e-posters, parent and infant facilities, two drinks evenings, and a new final night after-party.  Registration and abstract submission is now open at http://soa.ics.ac.uk.

We are very pleased to announce the 6th International Fluid Academy Days (iFAD), which will take place on November 23-25th 2017 at the Hilton Hotel in Antwerp, Belgium. The iFAD is an innovative Critical Care Educational meeting in true SMACC spirit. This conference provides the highest quality of Critical Care education and is guaranteed to innovate and inspire. Recent advances in fluid management, and hemodynamic and organ function monitoring in the critical care setting will be reviewed in a comprehensive manner for intensivists, anaesthesiologists and emergency physicians as well as interested internists and surgeons.

The iFAD Faculty is the most provocative, engaging, motivating and inspiring group of international educational speakers and as organizing committee we want to ensure we have the participants, sponsors and endorsers to match. Together, we make iFAD stand apart from other Critical Care conferences.