Welcome to the 231st Critical Care Reviews Newsletter, bringing you the most important research and open access articles from the past seven days. For the third and final week, along with some friends, I'm asking for some help! See the message below from Paul Young.
"You are invited to participate in a survey designed to provide estimates of ‘pre-test probability’ that hypotheses for major ongoing trials in critically ill adults are correct. These probability estimates will then be used to aid our understanding of what the trial results mean when the trials are completed. We think that you will find the survey interesting to complete because it will provide some information about major ongoing trials in the field. We estimate that it will take you around 10 minutes to do. We want as many Critical Care Reviews subscribers as possible to respond to the survey.In order to record the number of people who could complete the survey, we're asking you to register for the newsletter and complete it via this route."
To celebrate the recruitment of the first patient into the REST Trial, this week's Topic of the Week is carbon dioxide, starting with a paper on extracorporeal CO2 removal: Technical and physiological fundaments in tomorrow's Paper of the Day.
- Abstract: van Lieshout. Nurses versus physician-led interhospital critical care transport: a randomized non-inferiority trial. Intensive Care Med 2016;epublished May 11th
- Full Text: Jena. Comparison of suction above cuff and standard endotracheal tubes in neurological patients for the incidence of ventilator-associated pneumonia and in-hospital outcome: A randomized controlled pilot study. Indian J Crit Care Med 2016;20:261-6
- Abstract: Veldeman. Delayed cerebral ischaemia prevention and treatment after aneurysmal subarachnoid haemorrhage: a systematic review. Br J Anaesth 2016;epublished May 8th
- Full Text: Liu. Regional citrate versus heparin anticoagulation for continuous renal replacement therapy in critically ill patients: a meta-analysis with trial sequential analysis of randomized controlled trials. Crit Care 2016;20(1):144
- Full Text: Yeung. Speckle tracking echocardiography in patients with septic shock: a case control study (SPECKSS). Critical Care 2016;20:145
- Full Text: Wafaisade. Prehospital administration of tranexamic acid in trauma patients. Critical Care 2016;20:143
- Full Text: Matsumura. Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study. Critical Care 2016;20:141
- Abstract: Hagiwara. Can Early Aggressive Administration of Fresh Frozen Plasma Improve Outcomes in Patients with Severe Blunt Trauma?—a Report by the Japanese Association for the Surgery of Trauma. Shock 2016;45(5):495–501
- Abstract: Cameron. One-Year Outcomes in Caregivers of Critically Ill Patients (RECOVER Program). N Engl J Med 2016;374:1831-1841
- Abstract: Antonucci. The Impact of Renal Failure and Renal Replacement Therapy on Outcome During Extracorporeal Membrane Oxygenation Therapy. Artificial Organs 2016;epublished May 2nd
- Abstract: Sjoding. Acute Respiratory Distress Syndrome Measurement Error: Potential Effect on Clinical Study Results. Annals ATS 2016;epublished May 9th
- Abstract: Maley. Resilience in Survivors of Critical Illness in the Context of the Survivors’ Experience and Recovery. Annals ATS 2016;epublished May 9th
- Moreno. Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm. Cochrane Database of Systematic Reviews 2016, Issue 5. Art. No.: CD011664
- Hewitt. Lateral positioning for critically ill adult patients. Cochrane Database of Systematic Reviews 2016, Issue 5. Art. No.: CD007205
- Estcourt. Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD005339
- Griffiths. Intravenous magnesium sulfate for treating children with acute asthma in the emergency department. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD011050
- Prasad. Corticosteroids for managing tuberculous meningitis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD002244
- Gluud. Non-absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD003044
- Gurusamy. Interventions for necrotising pancreatitis. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD011383
- Madrid. Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database of Systematic Reviews 2016, Issue 4. Art. No.: CD009016
- Gupta. Intensive care management of status epilepticus. J Neuroanaesthesiol Crit Care 2016;3:83-95
- Bindra. Targeted temperature management in neurocritical care: Boon or bust. J Neuroanaesthesiol Crit Care 2016;3:96-109
- Manara. A case for stopping the early withdrawal of life sustaining therapies in patients with devastating brain injuries. JICS 2016;epublished May 5th
- Kumar. Brain death and care of the organ donor. J Anaesthesiol Clin Pharmacol 2016;32:146-52
- Gorlin. Intravenous sub-anesthetic ketamine for perioperative analgesia. J Anaesthesiol Clin Pharmacol 2016;32:160-7
- Karnjuš. Inhalation sedation with the ‘Anaesthetic Conserving Device’ for patients in intensive care units: A literature review. SIGNA VITAE 2016; 11(1):1-24
- Kulkarni. Extracorporeal membrane oxygenation in adults: A practical guide for internists. CCJM 2016;83(5):373-384
- Longworth. Tracheostomy in special groups of critically ill patients: Who, when, and where?. Indian J Crit Care Med 2016;20:280-4
- Gariani. Effects of liver transplantation on endocrine function: A systematic review. Liver Int 2016;epublished May 10th
- Aboseif. Role of anesthesiologists in the management of trauma patients: Updates. Ain-Shams J Anaesthesiol 2016;9:153-8
- Godat. Thoracoscopic Management of Traumatic Sequelae. Curr Trauma Rep 2016;epublished April 30th
- Miller. Early Enteral Nutrition in Trauma: Is There Still Any Doubt? Curr Trauma Rep 2016;epublished April 29th
- Robins. Fracture Care Challenges in Austere and Combat Environments. Curr Trauma Rep 2016;epublished April 27th
- Gellman. Fracture Care Challenges in the Austere and Humanitarian Environments. Curr Trauma Rep 2016;epublished April 26th
- Shields. Cutting-Edge Forward Burn Nutrition: from the Battlefield to the Burn Center. Curr Trauma Rep 2016;epublished April 25th
- Kagan. Is Total Parenteral Nutrition (TPN) an Evil in Trauma Patients? Curr Trauma Rep 2016;epublished April 22nd
- Chouinard. The Acute Management of Facial Fractures. Curr Trauma Rep 2016;epublished April 15th
- Stump. Fat Embolism Syndrome: Fact or Myth? Curr Trauma Rep 2016;epublished April 15th
- Kaur. Amniotic fluid embolism. J Anaesthesiol Clin Pharmacol 2016;32:153-9
- Lipner. Evaluation of nail lines: Color and shape hold clues. CCJM 2016;83(5):385-391
- Grier. The relocation and road transfer of intensive care patients to a new hospital in Bristol: Our experiences. JICS 2016;epublished May 12th
- Anderson. Can open-source drug development deliver? Lancet 2016;387(10032):1983–1984
- Thomas. The United Kingdom National Audit Projects: a narrative review. South Afr J Anaesth Analg 2016;22(2):38–45
- Bonaventure. Managing critically ill patients with severe traumatic brain injury: How should we season the recipe? Can J Anesth 2016;63:647–651
- Rasmussen. Enhanced recovery programmes for the elderly. European Journal of Anaesthesiology 2016;33(6):391–392
- Goyal. Dexmedetomidine: The game changer or a team player?. J Anaesthesiol Clin Pharmacol 2016;32:144-5
- Gracious. Maximizing organ yield from deceased Lead donors. J Anaesthesiol Clin Pharmacol 2016;32:143
- Protti. The delicate balance between pro-(risk of thrombosis) and anti-(risk of bleeding) coagulation during extracorporeal membrane oxygenation. Ann Transl Med 2016;4(7):139
- Rijkenberg. Can the critical-care pain observation tool (CPOT) be used to assess pain in delirious ICU patients? J Thorac Dis 2016;8(5):E285-E287
- Revest. Adjuvant corticosteroids for patients hospitalized with community-acquired pneumonia: is it time? J Thorac Dis 2016;8(5):E288-E291
- Trivedi. Utility of the Richmond Agitation-Sedation Scale in evaluation of acute neurologic dysfunction in the intensive care unit. J Thorac Dis 2016;8(5):E292-E294
- Cobianchi. Serum lactate level as a useful predictor of clinical outcome after surgery: an unfulfilled potential? J Thorac Dis 2016;8(5):E295-E297
- Gattinoni. Ultra-protective ventilation and hypoxemia. Critical Care 2016;20:130
- Bozza. Key points on Zika infection for the intensivist. Intensive Care Med 2016;epublished May 12th
- Kapoor. Robotized surgical assistant in neurosurgery: Anaesthetic implications!. J Neuroanaesthesiol Crit Care 2016;3:151-2
- Bein. From Berlin to Kigali: the sobering journey of acute respiratory distress syndrome. J Thorac Dis 2016;8(5):E282-E284
- Thongprayoon. Serum creatinine level, a surrogate of muscle mass, predicts mortality in critically ill patients. J Thorac Dis 2016;8(5):E305-E311
- Tsirigotis. Balanced control of both hyper and hypo-inflammatory phases as a new treatment paradigm in sepsis. J Thorac Dis 2016;8(5):E312-E316
- Perner. Is the concept of fluid responsiveness evidence-based? Response to comments by Saleh. Intensive Care Med 2016;epublished May 3rd
- Buck. More on Data Sharing. N Engl J Med 2016;374:1895-1897
- Platt. Challenges for Sharing Data from Embedded Research. N Engl J Med 2016;374:1897
- Kalager. Recognizing Data Generation. N Engl J Med 2016; 374:1898
- May. This is not an acute coronary syndrome. CCJM 2016;83(5):335-336
- Paliwal. Off-pump awake coronary artery bypass grafting under high thoracic epidural anesthesia. J Anaesthesiol Clin Pharmacol 2016;32:261-2
- Garg. Extracorporeal treatment with high-volume continuous venovenous hemodiafiltration and charcoal-based sorbent hemoperfusion for severe metformin-associated lactic acidosis. Indian J Crit Care Med 2016;20:295-8
- Yuan. Postperfusion lung syndrome and related sequelae. J Thorac Dis 2016;8(5):E340-E344
There is only one month to SMACC DUB. If you haven't yet booked your pre-conference workshop, then the "Stop Gambling - Applying Evidence to Practice" session comes highly recommended (...cough...). You will be encouraged to doubt the ground on which you stand, then come to terms with how we handle that uncertainty in real life practice – without becoming a nihilist.
The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.
A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day. Book before 1st May to avail of the Early Bird option of €30 (limited availability).
Please contact Louise at firstname.lastname@example.org to register for the meeting and meal.
The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. The meeting programme and registration are available on the brand new, and beautiful, Intensive Care Society of Ireland website.
The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. The website has caught a cold, but will be back up very soon.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week