Critical Care Reviews Newsletter
Newsletter 501 | July 19th 2021
Three Major Trial Results Livestreams Coming Up
Welcome to the 501st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19 & the impact of nursing delirium preventive interventions in the ICU; systematic reviews and meta analyses on platelet-to-red blood cell ratio and mortality in bleeding trauma patients & higher versus lower positive end-expiratory pressure in patients without ARDS; and observational studies on extracorporeal membrane oxygenation for COVID-19–associated severe ARDS in Chile & 3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation.
There is also a military guideline on whole blood transfusion; narrative reviews on emerging SARS-CoV-2 variants of concern and potential intervention approaches & precision medicine and heterogeneity of treatment effect in therapies for ARDS; editorials on acute myocardial infarction with cardiogenic shock & writing a narrative review article; and a commentary on recovery after prolonged ICU treatment in patients with COVID-19.
If you only have time to read one review article this week, try this one on acute kidney injury.
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Research
Randomised Controlled Trials
- Arabi. Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. Intensive Care Med 2021;epublished July 12th
- Adi. Randomized clinical trial comparing helmet continuous positive airway pressure (hCPAP) to facemask continuous positive airway pressure (fCPAP) for the treatment of acute respiratory failure in the emergency department. Am J Emerg Med 2021;49:385-392
- Rood. The Impact of Nursing Delirium Preventive Interventions in the Intensive Care Unit: A Multicenter Cluster Randomized Controlled Trial (UNDERPIN-ICU). Am J Resp Crit Care Med 2021;epublished June 25th
- Zarbock. Prevention of Cardiac Surgery–Associated Acute Kidney Injury by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI-Multicenter Randomized Controlled Trial. Anesth Analg 2021;133(2):292-302
- Dougan. Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19. N Engl J Med 2021;epublished July 14th
- Preprint: Sholzberg. Heparin for Moderately Ill Patients with Covid-19 (RAPID Trial). MedRxiv 2021;epublished July 12th
Systematic Reviews & Meta Analyses
- Kleinveld. Platelet-to-red blood cell ratio and mortality in bleeding trauma patients: A systematic review and meta-analysis Transfusion 2021;61 Suppl 1:S243-S251
- Pettenuzzo. Higher versus lower positive end-expiratory pressure in patients without acute respiratory distress syndrome: a meta-analysis of randomized controlled trials. Crit Care 2021;25:247
- Ling. Venoarterial extracorporeal membrane oxygenation as mechanical circulatory support in adult septic shock: a systematic review and meta-analysis with individual participant data meta-regression analysis. Crit Care 2021;25:246
- Gracie. The Association of Preoperative Frailty and Postoperative Delirium: A Meta-analysis. Anesth Analg 2021;133(2):314-32
- Haug. Long-term sequelae of critical illness in sepsis, trauma and burns. a systematic review and meta-analysis. J Trauma Acute Care Surg 2021;epublished July 9th
- Gomez. Transcranial Doppler Based Cerebrovascular Reactivity Indices in Adult Traumatic Brain Injury: A Scoping Review of Associations With Patient Oriented Outcomes. Front Pharmacol 2021;epublished July 6th
Observational Studies
- Diaz. Extracorporeal Membrane Oxygenation for COVID-19–associated Severe Acute Respiratory Distress Syndrome in Chile: A Nationwide Incidence and Cohort Study. Am J Respir Crit Care Med 2021;204(1):34–43
- Ray. Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study. Lancet Child Adolesc Health 2021;epublished July 14th
- Ma. Individualized resuscitation strategy for septic shock formalized by finite mixture modeling and dynamic treatment regimen. Crit Care 2021;25:243
- Wu. 3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study. Lancet Respir Med 2021;9(7):747-754
- de Freitas. Resuscitation fluid practices in Brazilian intensive care units: a secondary analysis of Fluid-TRIPS. Rev Bras Ter Intensiva 2021;33(2):206-218
- Wang. Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection. Nature 2021;595:426–431
- Wozniak. Mental health outcomes of ICU and non-ICU healthcare workers during the COVID-19 outbreak: a cross-sectional study. Ann Intensive Care 2021;11:106
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Guidelines
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Reviews
COVID-19
- Khateeb. Emerging SARS-CoV-2 variants of concern and potential intervention approaches. Crit Care 2021;25:244
- Pati. Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products. Transfusion 2021;61 Suppl 1:S336-S347
- van de Veerdonk. COVID-19-associated Aspergillus tracheobronchitis: the interplay between viral tropism, host defence, and fungal invasion. Lancet Respir Med 2021;9(7):795-802
- Nunes. Use of medicines for covid-19 treatment in patients with loss of kidney function: a narrative review. J Bras Nefrol 2021;43(2):254–262
Neurological
Respiratory
- Pelosi. Personalized mechanical ventilation in acute respiratory distress syndrome. Crit Care 2021;25:250
- Khan. Precision Medicine and Heterogeneity of Treatment Effect in Therapies for Acute Respiratory Distress Syndrome. Chest 2021;epublished July 13th
- Wang. The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19. Front Pharmacol 2021;12:698905
- Chong. Comparing Central Venous Blood Gas to Arterial Blood Gas and Determining Its Utility in Critically Ill Patients: Narrative Review. Anesth Analg 2021;133(2):374-378
- da Silva Moura. Extubation in the pediatric intensive care unit: predictive methods. An integrative literature review. Rev Bras Ter Intensiva 2021;33(2):304-311
Renal
- Kellum. Acute kidney injury. Nat Rev Dis Primers 2021;7:52
- Batte. Malaria-Associated Acute Kidney Injury in African Children: Prevalence, Pathophysiology, Impact, and Management Challenges. Int J Nephrol Renovasc Dis 2021 Jul 8;14:235-253
Perioperative
Miscellaneous
Non-Clinical
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Editorials
- Chaney. So You Want to Write a Narrative Review Article? J Cardiothorac Vasc Anesth 2021;epublished June 18th
- Kiefer. Acute Myocardial Infarction with Cardiogenic Shock – navigating the invasive options in clinical management. J Cardiothorac Vasc Anesth 2021;epublished July 13th
- Pospishil. Contemporary Practice of Echocardiography in Transcatheter Aortic Valve Replacement. J Cardiothorac Vasc Anesth 2021;epublished July 14th
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Commentaries
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Correspondence
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Case Reports
- Moses. Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria. N Engl J Med 2021; 385:217-227
- Garg. Triple whammy! Steroids, strongyloidiasis and septic meningitis. Ann Indian Acad Neurol 2021;24:461-3
- Alves da Silva, Neurological dysfunction associated with COVID-19. Rev Bras Ter Intensiva 2021;33(2):325-325
- Guedri. A rare cause of cyanosis: Congenital methemoglobinemia. Clin Case Rep 2021;9(7):e04422
- Bae. Coombs-negative hemolytic anemia in a male with COVID-19. Clin Case Rep 2021;9(7):e04503
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Multimedia
I hope you find this newsletter useful.
Until next week
Rob
Supported by the Health Research Board
