Welcome to the 499th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are a randomised controlled trial on individualized PEEP guided by electrical impedance tomography in ARDS; a systematic review and meta analysis on invasive mould disease in fatal COVID-19; and an observational study on prone positioning and survival in mechanically ventilated patients with Coronavirus disease 2019-related respiratory failure. There are also guidelines on the management of pediatric patients with oxygen in the acute care setting & the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis; narrative reviews on acute kidney injury in the critically ill & the evolution of the use of extracorporeal membrane oxygenation in respiratory failure; an editorial on preoperative assessment and optimisation; a commentary on delirium in COVID-19; as well as correspondence on the ARREST trial.
If you only have time to read one review article this week, try this one on prehospital resuscitation.
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Research
Randomised Controlled Trials
- He. Early individualized positive end-expiratory pressure guided by electrical impedance tomography in acute respiratory distress syndrome: a randomized controlled clinical trial. Crit Care 2021;25(1):230
- Luckraz. Reduction in acute kidney injury post cardiac surgery using balanced forced diuresis: a randomized, controlled trial. Eur J Cardiothorac Surg 2021;59(3):562-569
Systematic Reviews & Meta Analyses
- Chan. Transmission of Severe Acute Respiratory Syndrome Coronavirus 1 and Severe Acute Respiratory Syndrome Coronavirus 2 During Aerosol-Generating Procedures in Critical Care: A Systematic Review and Meta-Analysis of Observational Studies. Crit Care Med 2021;49(7):1159-1168
- Wang. Effect of dexmedetomidine on delirium during sedation in adult patients in intensive care units: A systematic review and meta-analysis. J Clin Anesth 2021;69:110157
- Shao. Effect of different levels of PEEP on mortality in ICU patients without acute respiratory distress syndrome: systematic review and meta-analysis with trial sequential analysis. J Crit Care 2021;epublished July 3rd
- Tang. Effectiveness and safety of adjunctive inhaled antibiotics for ventilator-associated pneumonia: A systematic review and meta-analysis of randomized controlled trials. J Crit Care 2021;65:133-139
- Yuan. Neurally adjusted ventilatory assist as a weaning mode for adults with invasive mechanical ventilation: a systematic review and meta-analysis. Crit Care 2021;25:222
- Kula. Invasive mould disease in fatal COVID-19: a systematic review of autopsies. Lancet Microbe 2021;epublished June 23rd
Observational Studies
- Rabie. Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and India. Intensive Care Med 2021;epublished June 22nd
- Cohen. The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock. Intensive Care Med 2021;epublished June 29th
- Guinchard. Informed consent in critically ill adults participating to a randomized trial. Brain Behav 2021;11(2):e01965
- Mathews. Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Respiratory Failure. Crit Care Med 2021;49(7):1026-1037
- Vera. Intubation timing as determinant of outcome in patients with acute respiratory distress syndrome by SARS-CoV-2 infection. J Crit Care 2021;65:164-169
- van Kammen. Frequency of Thrombocytopenia and Platelet Factor 4/Heparin Antibodies in Patients With Cerebral Venous Sinus Thrombosis Prior to the COVID-19 Pandemic. JAMA 2021;epublished July 2nd
- Fronczek. Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study. Crit Care 2021;25:231
- Pham. Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study. Eur Respir J 2021;57:2003317
- Chary. Gender disparity in critical care publications: a novel Female First Author Index. Ann Intensive Care 2021;11(1):103
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Guidelines
- AARC Clinical Practice Guideline: Management of Pediatric Patients With Oxygen in the Acute Care Setting. Respir Care 2021;66:1214-1223
- Verweij. Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis. Intensive Care Med 2021;epublished June 23rd
- Nunnally. The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis. Intensive Care Med Exp 2021;9(1):34
- Emergent Truncal Hemorrhage Control Study Group. Determination of optimal deployment strategy for REBOA in patients with non-compressible hemorrhage below the diaphragm. Trauma Surgery & Acute Care Open 2021;6:e000660
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Reviews
COVID-19
- Schober. Neurologic Manifestations of COVID-19 in Children: Emerging Pathophysiologic Insights. Ped Crit Care Med 2021;22(7):655-661
- Saunders. 2020 Year in Review: Pharmacologic Treatments for COVID-19. Respir Care 2021;66(7):1167-1172
- Smarz-Widelska. Pathophysiology and Clinical Manifestations of COVID-19-Related Acute Kidney Injury-The Current State of Knowledge and Future Perspectives. Int J Mol Sci 2021;22(13):708
- Carretta. Cardiac Involvement in COVID-19 Patients: A Contemporary Review. Infect Dis Rep 2021;13(2):494-517
- Bonnemain. The Right Ventricle in COVID-19. J Clin Med 2021;10(12):2535
Neurological
- Khazanova. A matter of timing: EEG monitoring for neurological prognostication after cardiac arrest in the era of targeted temperature management. Minerva Anestesiologica 2021;87(6):704-13
- Chun. Updates on neurologic complications in pediatric regional anesthesia. Minerva Anestesiologica 2021;87(6):695-703
Respiratory
- Feldhaus. The Evolution of the Use of Extracorporeal Membrane Oxygenation in Respiratory Failure. Membranes 2021;11(7):491
- Carteaux. Patient-Self Inflicted Lung Injury: A Practical Review. J Clin Med 2021;10(12):2738
- Andersen. Upper Airway Assessment and Responses During Mechanically Assisted Cough. Respir Care 2021;66:1196-1213
Renal
Haematological
Sepsis
Trauma
Burns
- Zhang. The pathogenesis and diagnosis of sepsis post burn injury. Burns Trauma 2021;9:tkaa047
- Song. Extracorporeal membrane oxygenation combined with continuous renal replacement therapy for the treatment of severe burns: current status and challenges. Burns Trauma 2021;9:tkab017
Paediatrics
Obstetrics
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Editorials
- Clohisey. Genome-wide association studies in ARDS: SNPing the tangled web of heterogeneity. Intensive Care Med 2021;epublished June 26th
- McNally. Preoperative assessment and optimisation: the key to good outcomes after the pandemic. Br J Hosp Med 2021;82(6):1-6
- Credland. Humanizing critical care. Nurs Crit Care 2021;26(4):222-223
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Commentaries
- Wilcox. Delirium in COVID-19: can we make the unknowns knowns?. Intensive Care Med 2021;epublished June 30th
- Xie. Critical care after the COVID-19 outbreak in China: lessons and renaissance. Intensive Care Med 2021;epublished June 22nd
- Bose. Placing the results of the SOLIDARITY trial with regards to remdesivir in perspective. Lung India 2021;38:382-6
- Kirby. Elisa Estenssoro: a career devoted to critical care. Lancet Respir Med 2021;epublished July 2nd
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Correspondence
- Lepper. Lung transplantation for COVID-19-associated ARDS. Lancet Respir Med 2021;epublished July 2nd
- Messika. Lung transplantation for COVID-19-associated ARDS. Lancet Respir Med 2021;epublished July 2nd
- Hutin. Refractory cardiac arrest: when timing is crucial. Lancet 2021;398(10294):22-23
- Jimenez. Tranexamic acid for subarachnoid haemorrhage. Lancet 2021;398(10294):25
- Heldeweg. Determining the optimal number of lung ultrasound zones to monitor COVID-19 patients: can we keep it ultra-short and ultra-simple?. Intensive Care Med 2021;epublished June 26th
- Meersseman. Secondary sclerosing cholangitis: an emerging complication in critically ill COVID-19 patients. Intensive Care Med 2021;epublished June 29th
- Cour. Differential effects of prone position in COVID-19-related ARDS in low and high recruiters. Intensive Care Med 2021;epublished June 28th
- Sanfilippo. COVID-19, pneumomediastinum and echocardiography: friends or foes? Minerva Anestesiologica 2021;87(6):739-40
- Honore. Success rate of naso-jejunal tube placement influenced by CRRT: possible removal of metoclopramide. Crit Care 2021;25:228
- Jouffroy. The impact of frailty on survival in elderly intensive care patients with COVID‑19: do not dismiss intensive care unit overcrowding. Crit Care 2021;25:225
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Case Reports
- Pai. Oxygen delivery failure due to improper installation of carbon dioxide absorbent canister: a case report. Braz J Anesthesiol 2021;71(4):443-446
- Veiga. Omega-shaped epiglottis: a challenge. Braz J Anesthesiol 2021;71(4):464-465
- Ramos Perkis. Challenges in acute care surgery: penetrating vertebral artery injury in ‘extremis’ patient. Trauma Surgery & Acute Care Open 2021;6:e000684
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Multimedia
I hope you find this newsletter useful.
Until next week
Rob
Supported by the Health Research Board
