Bolus Versus Continuous Infusion of Meropenem (MERCY)

Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive TransfusionThe PROCOAG Randomized Clinical Trial

A Randomised Multiple Centre Trial of Conservative versus Liberal Oxygenation Targets in Critically Ill Children

Early high-dose cryoprecipitate in adult patients with major trauma haemorrhage

Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial

The Prehospital Antifibrinolytics for Traumatic Coagulopathy and Haemorrhage (PATCH-Trauma) Trial

Early Active Mobilization during Mechanical Ventilation in the ICU

The TEAM Study Investigators and the ANZICS Clinical Trials Group. Early Active Mobilization during Mechanical Ventilation in the ICU. N Engl J Med 2022;387:1747-1758

Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) for trauma patients with uncontrolled torso haemorrhage

Direct versus video laryngoscopy in critically ill adults undergoing emergency tracheal intubation

Haloperidol for the Treatment of Delirium in ICU Patients

Andersen-Ranberg. Haloperidol for the Treatment of Delirium in ICU Patients. N Engl J Med 2022;387:2425-2435

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension

The National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. N Engl J Med 2023;epublished January 21st

Check out this short video from the Critical Care Reviews Meeting 2022. If you're interested in critical care trials, this is the meeting for you.

In June 2022, we hosted 5 major trial results, including LOVIT, SUDDICU, FIRST-ABC, PREPARE2 and CLASSIC, as well as meta analysis on vitamin C in sepsis and hypothermia for cardiac arrest. Four of the major trial result presentations were simultaneously published in the New England Journal of Medicine or JAMA, and two systematic reviews & meta analysis were simultaneously published in NEJM Evidence. A further position paper was published in Nature Medicine.

This is a relative small, intimate, niche meeting. In 2022, delegates attended from 26 countries and every corner of the globe. If you plan on coming, please book as soon as possible to avoid disapointment. As our venue capacity is fixed, when tickets are sold out, we're full!

The Critical Care Reviews Meeting is a truly unique event, where our aim is to share science rather than make money. For those who can't attend in person, we will be livestreaming the event for free. All talks are recorded and made freely available on the CCR website. Our annual book, summarising the best trials of the previous year, is given to delegates and a pdf copy made freely available for downloading. For those who do make it, we aim to have a minimal impact on our environment, with carbon offsetting in the form of tree planting, no plastics, and a focus on local food. We provide unrivalled on-site childcare at minimal cost, reduced maternity and paternity rates and a baby feeding area. We try to match scientific excellence with global equity and environmental responsibility. Critical Care Reviews is not-for-profit.

While we take pride in providing a culturally rounded event, the Critical Care Reviews Meeting is a scientific conference, highlighting the best critical care trials in the world. We host major trial results and review the best trials of the previous 12 months. Every trial result is allocated a full 90 minute session, including 30 minutes for the results presentation, 15 minutes for an independent editorial, 10 minutes open questions and a 30 minute expert panel discussion. Reviews of previously published trials get 40 minutes, again with an independent editorial. In the mornings, we host major trial results; in the early afternoon we review major trials published over the preceding year; and in the late afternoon, we change pace with expert panel discussions on various aspects of trial methodology, design, interpertation, dissemination and publishing.

The vibe of our Meeting is different too, with high class science presented and discussed in a open,friendly format. in Our social programme matches our scientific programme, with superb night events, as well as early morning exercise options. Alternatively, take the time to explore our home city Belfast, which is remarkably vibrant and culturally rich. If you have time to stay for a few days or longer, get outside the city and explore the island - there are few more beautiful places in the world.