Major Trial Results Livestreams
CCR Livestreams
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Typically 90 minutes to 2 hours in length
Latest Livestream
PILOT trial
The PILOT trial compares three different oxygenation targets in critically ill mechanically ventilated patients - SpO2 90% vs 94% vs 98%
Monday, October 24th
20:00 UTC + 1
Previous Livestreams
2022
2021
BOUGIE | COCA | COVID-STEROID 2 | VAM-IHCA | COVID-19 Anticoagulation | RECOVERY-RS | BaSICS | TTM2 | REMAP-CAP IL-6 RA
NITRIC Trial
NITRIC Trial Results Presentation
Prof Luregn Schlapbach (Zurich, Switzerland)
Editorial
Prof Mark Peters (London, England)
Viewer's Questions
Dr Bronwen Connolly (Belfast, Northern Ireland)
Answers from Prof Luregn Schlapbach (Zurich, Switzerland)
Panel Discussion
Rob Mac Sweeney (Belfast, Northern Ireland) hosts a panel discussion including Prof Paul Checchia (Houston, USA), Prof Wes Diddle (Washington DC, USA), Prof Ranjit Lall (Coventry, England), Prof Kathy Rowan (London, England), as well as the NITRIC trial chief investigator Luregn Schlapbach (Zurich, Switzerland) and editorialist Prof Mark Peters (London, England)
PLUS Trial and Balanced Solutions Systematic Review
PLUS Trial Results Presentation
Prof Simon Finfer (Sydney, Australia)
Balanced Crystalloids Systematic Review Results Presentation
Assoc Prof Naomi Hammond (Sydney, Australia)
Editorial
Prof Deborah Cook (Hamilton, Canada)
Viewer's Questions
Dr Murali Shyamsundar (Belfast, Northern Ireland)
Answers from Prof Simon Finfer & Assoc Prof Naomi Hammond (both Sydney, Australia)
Panel Discussion
Rob Mac Sweeney hosts a panel discussion on the results of the PLUS trial, including Prof John Kellum (Pittsburgh, USA), Prof Gordon Guyatt (Hamilton, Canada), Dr Tomoko Fujii (Tokyo, Japan) & Prof Jeff Drazen (Boston, USA)
BOUGIE Trial
BOUGIE Trial Results Presentation
Drs Jon Casey (Nashville, USA), Stacy Trent (Denver, USA) and Brian Driver (Minneapolis, USA)
Editorial
Prof Sheila Nainan Myatra (Mumbai, India).
Replies from Dr Brian Driver (Minneapolis, USA) & Dr Matt Semler (Nasville, USA), plus comments from Prof Jonathan Benger (Bristol, England).
Viewer's Questions
Dr Chris Nutt (Bellfast, Northern Ireland).
Replies from Dr Brian Driver (Minneapolis, USA) & Dr Matt Semler (Nasville, USA)
Panel Discussion
Prof Jonathan Benger (Bristol, England), Dr Jean-Baptiste Lascarrou (Nantes, France), George Kovacs (Halifax, Canada), Dr Jon Casey (Nasville, USA), Dr Stacy Trent (Denver, USA), Dr Brian Driver (Minneapolis, USA) & Dr Matt Semler (Nasville, USA). Chaired by Dr Rob Mac Sweeney (Bellfast, Northern Ireland).
COCA Trial
COCA Trial Results Presentation
Dr Mikael Fink Vallentin and Lars Andersen (Aarhus, Denmark)
Editorial
Prof Gavin Perkins (Coventry, England)
Viewer's Questions
Dr Chris Nutt (Belfast, Northern Ireland)
Panel Discussion
Prof Theresa Olasveengen (Oslo, Norway), Dr Victoria Cornelius (London, England), Prof Christopher Seymour (Pittsburgh, USA), Prof Gavin Perkins (Coventry, England), Dr Mikael Fink Vallentin & Prof Lars Andersen (Aarhus, Denmark)
COVID-STEROID 2 Trial
COVID STEROID 2 Trial Results Presentation
Prof Sheila Nainan Myatra (Mumbai, India), Prof Bala Ventakesh (Brisbane, Australia), Prof Anders Perner (Copenhagen, Denmark)
Editorial
Prof Marion Campbell (Aberdeen, Scotland)
Viewer's Questions
Dr Chris Nutt (Belfast, Northern Ireland)
Panel Discussion
Prof Bram Rochwerg (Hamilton, Canada), Dr Paul Mouncey (London, England) & Prof Colin McArthur (Auckland, New Zealand), Prof Sheila Nainan Myatra (Mumbai, India), Prof Bala Ventakesh (Brisbane, Australia), Prof Anders Perner (Copenhagen, Denmark), Prof Marion Campbell (Aberdeen, Scotland).
The HOPE Trial
Research Challenges during a Pandemic
Dr Bharath Kumar (Chennai, India)
VAM-IHCA Trial
VAM-IHCA Trial Results Presentation
Asger Granfeldt and Lars Wiuff Andersen (both Aarhus, Denmark)
Editorial
Prof Spyros Mentzelopoulos (Athens)
Viewer's Questions
Dr Chris Nutt (Belfast, Northern Ireland)
Panel Discussion
Katherine Berg (Boston), Bernd Böttiger (Cologne), Ranjit Lall (Coventry), Louise Morrison (Toronto), Spyros Mentzelopoulos (Athens), Lars Wiuff Andersen & Asger Granfeldt (Aarhus), Spyros Mentzelopoulos (Athens). Hosted by Rob Mac Sweeney (Belfast)
COVID-19 Anticoagulation Multi-Platform Trial
VAM-IHCA Trial Results Presentation
Drs Patrick Lawler (Toronto), Lindsay Berry (Austin) & Ewan Goligher (Toronto)
Editorial
Charlotte Summers (Cambridge)
Viewer's Questions
Dr Peter McGuigan (Belfast)
Panel Discussion
An international panel of experts discuss the robustness and implications of the COVID-19 Anticoagulation Trial at a livestreamed Critical Care Reviews Trial Results Meeting, on August 4th, 2021.The panel include Profs Judith Hochman (New York), Saskia Middledorp (Nijmegen) and James Douketis (Hamilton).
RECOVERY-RS Trial
RECOVERY-RS Trial Results Presentation
Drs Bronwen Connolly (Belfast) and Keith Couper (Coventry)
Editorial
Prof Manu Shankar-Hari (London)
Viewer's Questions
Dr Chris Nutt (Belfast)
Panel Discussion
Dr Rob Mac Sweeney (Belfast) hosts a panel discussion on the RECOVERY-RS trial. The panelists include Profs Leticia Kawano-Dourado (Sao Paulo), Janet Diaz (San Francisco) & John Norrie (Edinburgh), plus Dr Stephen Webb (Cambridge).
BaSICS Trial
BaSICS Trial Results Presentation
Dr Fernando Zampieri & Alexandre Biasi Cavalcante (São Paulo)
Editorial
Prof Simon Finfer (Sydney)
Viewer's Questions
Dr Bronwen Connolly (Belfast)
Panel Discussion
Rob Mac Sweeney hosts an international panel discussion on the results of the BaSICS trial. The panelists are Prof Kathryn Maitland (Kenya), Dr Tine Sylvest Meyhoff (Denmark), Assoc Prof Christopher Seymour (USA) & Asst. Prof Andrew Althouse (USA). They are joined by the lead trialists Drs Fernando Zampieri & Alexandre Biasi Cavalcante (both Brazil), as well Simon Finfer (Australia), who delivered an editorial on the trial.
Learnings from the BaSICS Trial
Dr Fernando Zampieri (São Paulo)
TTM2 Trial
Livestreamed June 16th, 2021
TTM2 Trial Results Presentation
Niklas Nielsen, Josef Dankiewicz and Gisela Lilja (all Lund)
Editorial
Stephen Bernard (Melbourne)
Viewer's Questions
Phil Gillen (Belfast)
Panel Discussion
Jerry Nolan (Bath), Kathy Rowan (London) and Terri Hough (Portland), join Stephen Bernard plus the TTM2 trial team of Niklas Nielsen, Josef Dankiewicz and Gisela Lilja (all Lund). Hosted by Rob Mac Sweeney (Belfast)
REMAP-CAP IL-6 Receptor Antagonist Domain Results Livestream
Livestreamed February 26th, 2021
Published Paper: The REMAP-CAP Investigators. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. N Engl J Med 2021;epublished February 25th
Dr Lennie Derde (Utrecht, The Netherlands)
This is the REMAP-CAP IL-6 receptor antagonist domain results presentation, recorded February 25th. The presentation was accompanied by a simultaneous publication in the New England Journal of Medicine.
Prof Derek Angus (Pittsburgh, USA) & Dr Liz Lorenzi (Berry Consultants, Austin, USA), set the scene with talks on the adaptive platform design of REMAP-CAP, and its underlying Bayesian framework, respectively. Next, Dr Lennie Derde (Utrecht, The Netherlands) presents the full results of the IL-6 receptor antagonist domain, followed by an independent editorial by Prof Tim Walsh (Edinburgh, Scotland). Lennie and her co-investigators reply to the editorial and questions from viewers. The session ends with a panel discussion, including external experts Dr David Harrison (Chief Statistician, ICNARC, London), Prof Anders Perner (Copenhagen, Denmark), and Prof Anthony Gordon (London, England), the lead investigator for the IL-6 RA domain at REMAP-CAP.
Session Timings
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1:37 - Derek Angus - The Beauty of Adaptive Designs
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19:22 - Liz Lorenzi -.The Statistical Framework of REMAP-CAP
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42:50 - Lennie Derde - The Results
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1:09:05 - Tim Walsh - The Editorial
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1:35:40 - Lennie Derde et al - Reply to the Editorial
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1:43:52 - Questions va Chris Nutt
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1:54:10 - Panel Discussion
