Topic of the Week May 16th to 22nd 2016 The REST Trial (Carbon Dioxide) Monday Romay. Extracorporeal CO2 removal: Technical and physiological fundaments and principal indications. Med Intensiva 2016;40:33-8 Tuesday Camporota. Current Applications for the Use of Extracorporeal Carbon Dioxide Removal in Critically Ill Patients. BioMed Research International 2016;2016:9781695 Wednesday Briva. Permissive and Non-permissive Hypercapnia: Mechanisms of Action and Consequences of High Carbon Dioxide Levels. Arch Bronconeumol 2010;46:378-82 Thursday Curley. Bench-to-bedside review: Carbon dioxide. Critical Care 2010, 14:220 Friday Kodali. Capnography during cardiopulmonary resuscitation: Current evidence and future directions. J Emerg Trauma Shock 2014;7:332-40 Saturday Vadász. Hypercapnia: a nonpermissive environment for the lung. Am J Respir Cell Mol Biol 2012;46(4):417-21 Sunday Bautista. Hypercapnia: is it protective in lung injury? Medical Gas Research 2013;3:23