Topic of the Week

November 3rd to 9th

Research Over-Interpretation - part II

Monday

• Collins. Reliable assessment of the effects of treatment on mortality and major morbidity. I. Clinical trials. Lancet 2001;357:373-380

Tuesday

• MacMahon. Reliable assessment of the effects of treatment on mortality and major morbidity, II: observational studies. Lancet 2014;357(9254):455-462

Wednesday

• Concato. Study Design and “Evidence” in Patient-oriented Research. Am J Respir Crit Care Med 2013;187(11):1167-1172

Thursday

• Albert. “Lies, Damned Lies …” and Observational Studies in Comparative Effectiveness Research". Am J Respir Crit Care Med 2013;187(11):1173-1177

Friday

• Wallace. Solving the challenges of large multicenter trials in anesthesia. HSR Proc Intensive Care Cardiovasc Anesth 2009;1(3):46-53

Saturday

• Delaney. Bench-to-bedside review: the evaluation of complex interventions in critical care. Crit Care 2008;12(2):210

Sunday

• Lewis. How to spot bias and other potential problems in randomised controlled trials. J Neurol Neurosurg Psychiatry 2004;75(2):181-7