CCR-Newsletter-BannerNewsletter 459  |  September 28th 2020

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Welcome to the 459th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on N-acetylcysteine for the treatment of severe acute respiratory syndrome caused by COVID-19, & rezafungin versus caspofungin for the treatment of candidemia and invasive candidiasis; systematic reviews and meta analyses on the attributable mortality of acute kidney injury, & clinical features and outcomes of adults with COVID-19; and observational studies on ECMO in COVID-19 & the association of RNAaemia and severe SARS-CoV-2 disease.

There ia also a guideline on the treatment of SARS-CoV-2 in ICU; narrative reviews on neurological dysfunction of critically ill COVID-19 patients & monitoring in patients receiving oxygen therapy; editorials on how systems engineering can improve care in the ICU & why it's always about numerators and denominators; and commentaries on first-generation COVID-19 vaccines & rapid review methods and knowledge synthesis.

This week's Topic of the Week is ventilator-induced lung injury, starting with a paper on emerging concepts in ventilation-induced lung injury in today's Paper of the Day.

If you only have time to read one review article this week, try this one on new agents in development for sepsis.

 

Research

Review Articles

COVID-19

Neurological

Circulatory

Respiratory

Sepsis

Trauma

Paediatrics

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

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