CCR-Newsletter-BannerNewsletter 443  |  June 11th 2020

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Welcome to the 443rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature last week. It's an absolutely massive newsletter, with the some sections left out of the emailed version for space reasons. They're in this desktop version of the newsletter. The highlights of this week's edition are randomised controlled trials on convalescent plasma therapy for life-threatening COVID-19 & hydroxychloroquine as postexposure prophylaxis for COVID-19; systematic reviews and meta analyses on fluid volumes during the initial management of sepsis & noninvasive oxygenation strategies in adults with acute hypoxemic respiratory failure; observational studies on patterns of use of adjunctive therapies in patients with early moderate to severe ARDS & thrombolytic door-to-needle time in acute ischemic stroke; and multiple COVID-19 trial protocols, including the REALIST-COVID-19 trial.

There are also guidelines on venous thromboembolism in patients with COVID-19 & tracheostomy during the COVID-19 pandemic; narrative reviews on ECMO use in COVID-19 & individualized blood pressure targets postcardiac arrest; editorials on fluid volume trials in sepsis  & COVID-19: first do no harm; and commentaries on reaffirming the value of evidence and equipoise while minimizing cognitive bias in the COVID-19 era & ten things we learned about COVID-19. If you only have time to read one review article this week, try this one on subphenotypes in critical care.



Review Articles









CCR21 Meeting

Due to the phenomenal success of CCR20, the Critical Care Reviews Meeting 2021 has been expanded to 3 days, allowing more time for major trial results presentations, as well as understanding the best clinical trials published during 2020. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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