CCR-Newsletter-BannerNewsletter 436  |  April 19th 2020

Journal Watch  |  Newsletters  |  CCR Meeting 2021  |  CCR18 BookPodcast  |  Hot Articles  |  Topic of the Week  |  Reviews  |  Top 100 Studies  |  Guidelines  |  Journals


Welcome to the 436th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature for the week of April 13th to 19th, 2020 (apologies - I'm slightly behind this week).

The highlights of this week's edition are randomised controlled trials on empirical high-dose meropenem in critically ill patients with sepsis and septic shock & the effect of intermittent or continuous feeding on muscle wasting in critical illness; systematic reviews and meta analyses on ventilator-associated pneumonia & antibiotic discontinuation strategies; and observational studies on prognosis for COVID-19 patients receiving ECMO in China & SARS-CoV-2 viral load in clinical samples of critically ill patients. There are also guidelines on COVID-19 airway management & triage of scarce critical care resources in COVID-19; narrative reviews on vasopressor and inotrope support in shock & basing respiratory management of coronavirus on physiological principles; editorials on different respiratory treatments for COVID-19 pneumonia phenotypes & drainage insufficiency on ECMO; and commentaries on scientific integrity and public confidence in a time of crisis & drug evaluation during the Covid-19 pandemic; as well as correspondence on ST-segment elevation in patients with Covid-19 & why driving pressure is not associated with mortality in non-ARDS patients.

The Topic of the Week is brain pathologies, starting with a paper on seizures in the ICU.

If you only have time to read one review article this week, try this old paper from JAMA, 1918, describing the Spanish influenza pandemic.



Review Articles









CCR21 Meeting

Due to the phenomenal success of CCR20, the Critical Care Reviews Meeting 2021 has been expanded to 3 days, allowing more time for major trial results presentations, as well as understanding the best clinical trials published during 2020. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until later in the week


Supported by the Health Research Board

ICCCTN logo Circular Text 100x100