CCR-Newsletter-BannerNewsletter 428  |  February 23rd 2020

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Welcome to the 428th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's been a quiet week for research publications, but there are still loads of great articles to read, including a guideline on assessment of sublingual microcirculation, narrative reviews on paediatric traumatic brain injury, anaphylaxiscerebral venous thrombosis and integration of bedside ultrasound into the ICU; editorials on nutritional management during noninvasive ventilation and maternal sepsis; commentaries on acute-on-chronic liver failure and cardiac output monitoring; plus correspondence on the long overdue banning of hydroxyethyl starch solutions.

This week's Topic of the Week is a selection of recent sepsis guidelines, starting with the Japanese guidelines for the management of sepsis and septic shock 2016 in tomorrow's Paper of the Day.


CCR21 Chair on Stage


Welcome to the 428th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. I'm going to restart with this week's newsletter and catch up with the missing newsletters as I can, so their numbering will reflect the week they cover, rather than the order they will be published in.

The highlights of this week's edition are randomised controlled trials on a driving pressure-limited strategy for ARDS & intrapulmonary concentrations of meropenem administered by continuous infusion; systematic reviews and meta analyses on neuromuscular blocking agent use in ARDS & the effect of continuous epinephrine infusion on survival in critically ill patients; and observational studies on the association of low baseline diaphragm muscle mass with prolonged mechanical ventilation and mortality among critically ill adults & a post hoc analysis of ANDROMEDA-SHOCK trial - capillary refill time status could identify different clinical phenotypes among septic shock patients fulfilling Sepsis-3 criteria.

There are also two guidelines on nutrition, in critically ill children & in acute pancreatitis, as well as a guideline on the management of adult acute and acute-on-chronic liver failure in the ICU. There are narrative reviews on airway pressure release ventilation & community-acquired pneumonia in critically ill very old patients; editorials on stress ulcer prophylaxis & intensive care during the coronavirus epidemic; and commentaries on ECMO for COVID-19-induced respiratory failure & what has been learned in responding to emerging zoonotic viruses; as well as correspondence on Immune biomarker-based enrichment in sepsis trials & plasma-first resuscitation to treat haemorrhagic shock in urban areas. 

This week's Topic of the Week will be out in the morning.

If you only have time to read one paper this week, try this one on Coronavirus disease 2019 (covid-19): a (radiological) perspective from china.



Review Articles

CCR21 Meeting

Registration is open!

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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