CCR-Newsletter-BannerNewsletter 420  |  December 29th 2019

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65 Session Programme

Just over two weeks to CCR20...

Happy New Year

Welcome to the 420th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are a randomised controlled trial on timing of staged nonculprit artery revascularization in patients with ST-segment elevation myocardial infarction; systematic reviews and meta analyses investigating terlipressin vs norepinephrine in septic shock & ketamine sedation in mechanically ventilated patients; and an observational study on a post hoc analysis of the ADRENAL trial. There are also guidelines on central venous access & management of the child's airway under anaesthesia; narrative reviews on neuroimaging in traumatic brain injury & the microcirculation; editorials on adjuvant vitamin C for sepsis & transcranial doppler; and commentaries on the responsibility of physicians to maintain competency & when could human challenge trials be deployed to combat emerging infectious diseases; as well as correspondence on global warming “heating up” the ICU through Candida auris infections & dynamic hyperinflation and intrinsic PEEP in ARDS patients.

This week's Topic of the Week is the COACT trial, starting with a paper on new perspectives for the management of non-ST elevation myocardial infarction after the COACT trial in tomorrow's Paper of the Day.

If you only have time to read one review article this week, try this one on organ dysfunction in sepsis.

 

Research

Review Articles

Neurological

Circulatory

Renal

Sepsis

Trauma

Miscellaneous

CCR20 Meeting

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation, as well as a panel discission on the proposed MEGA-ROX trial, potentially a game changer for critical care trials. We are delighted to have the opportunity to conduct a one-on-one interview with the editor-in-chief of JAMA, Prof Howard Bauchner, in discussion with Prof Marion Campbell. As usual, we eound off the formal programme with the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

For CCR20, we are hosting 3 major trial results presentations, PEPTIC, 65 & VITAMINS, plus the IHME Sepsis Study results, as well as discussing 9 of the best trials from 2019 - COACT, TRACT, ICU-ROX, SPICE III, BiRDS, ROSE, CITRIS-ALI, SEPSIS-ACT & HYPERION.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

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