CCR-Newsletter-BannerNewsletter 411  |  October 27th 2019

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Welcome to the 411th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. The highlights of this week's edition are randomised controlled trials comparing fibrinogen concentrate with cryoprecipitate after cardiac surgery & depths of anaesthesia in major surgery; systematic reviews and meta analyses on timing of initiation of renal replacement therapy for acute kidney injury & procalcitonin-guided antibiotic therapy; and observational studies on laryngeal injury after prolonged mechanical ventilation & IMPELLA mechanical support in patients with acute myocardial infarction complicated by cardiogenic shock. There are also narrative reviews on the perioperative stress response & technology-enabled clinical trials; and editorials on optimising power to avoid VILI & the role of sugammadex; as well as correspondence which has caused some controvery on social media, on sepsis hysteria

Continuing the build up to the Critical Care Reviews Meeting 2020, this week's Topic of the Week is the SPICE III trial, investigating dexmedetomidine sedation in ICU, starting with a paper on dexmedetomidine: present and future directions in tomorrow's Paper of the Day.

If you only have time to read one review article this week, try this one on complications of temporary percutaneous mechanical circulatory support for cardiogenic shock.

 

CCR20 201019

Research

Review Articles

Neurological

Circulatory

Respiratory

Hepatobiliary

Renal

Haematological

Sepsis

Perioperative

CCR20 Meeting

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

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