CCR-Newsletter-BannerNewsletter 408  |  October 8th 2019

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Welcome to the 408th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

It's a smaller newsletter than usual this week. The highlights of this edition are randomised controlled trials on the effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation & a Bayesian re-analysis of the ANDROMEDA-SHOCK trial; a systematic review and meta analysis comparing general anesthesia with procedural sedation in patients with acute ischemic stroke undergoing thrombectomy; and observational studies on vitamin D and acute respiratory infections & computed tomography angiography accuracy in brain death diagnosis. There are also guidelines on community-acquired pneumonia & prognostication in neurocritical care; narrative reviews on the failing right heart, reappraisal of ventilator-free days in critical care research & prone positioning in ARDS; editorials on patient selection in sepsis & the probability of benefit with the use of neuromuscular blockade in patients with ARDS; and commentaries on the importance of timing for the spontaneous breathing trial & lactate guided resuscitation.

This week's Topic of the Week is lung transplatation, which started yesterday with a paper on the indications for lung transplant referral and listing.

If you only have time to read one review article this week, try this one on emergent polymyxin resistance: end of an era?


CCR20 Oct


Review Articles






CCR20 Meeting

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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