CCR-Newsletter-BannerNewsletter 405  |  September 17th 2019

Journal Watch  |  Newsletters  |  CCR Meeting 2020  |  CCR18 BookPodcast  |  Hot Articles  |  Topic of the Week  |  Reviews  |  Top 100 Studies  |  Guidelines  |  Journals


Welcome to the 405th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on supplementation of vitamin D in neurocritical care patients & high-flow nasal cannulae versus non-invasive ventilation for preoxygenation of obese patients; systematic reviews and meta analyses on airway pressure release ventilation & selective digestive decontamination vs. selective oropharyngeal decontamination; and observational studies on prolonged versus brief ICU stay & the association between supra-physiologic arterial oxygen levels and mortality. There are also guidelines on acute and chronic heart failure & immune checkpoint inhibitor–related pneumonitis; narrative reviews on malignant hyperthermia & oral anticoagulant reversal strategies; editorials on crystalloids in sepsis & nasal high‐flow therapy; and commentaries on heart recovery after circulatory determination of death perioperative hemodynamic monitoring; as well as a study critique on the EOLIA trial

If you only have time to read one review article this week, try this one on new perspectives for the management of non-ST elevation myocardial infarction after the COACT trial - another great trial being discussed at CCR20!

The latest presentations from the Critical Care Reviews Meeting 2019 released this week are SMART & its editorial and SUP-ICU & its editorial. The previously released talks are available here.

Celebrating 25 years of the UK Intensive Care National Audit and Research Centre, this week's Topic of the Week focuses on some of the major trials ICNARC has undertaken (CALORIESProMISePOPPI - all previously discussed at CCR) and some currently running (65 - being discussed at CCR20) or being assisting with (PEPTIC - results being presented at CCR20; & REST, hopefully being discussed at CCR20something). We started yesterday with their landmark trial PAC-Man and finish on Sunday with the protocol for 65.



Review Articles











CCR20 Meeting

CCR20 010819 Widget

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

ICCCTN logo Circular Text 100x100