CCR-Newsletter-BannerNewsletter 389  |  May 26th 2019

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The latest addition to the #CCR20 programme is the SPICE III trial


Welcome to the 389th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on the effect of targeting mean arterial pressure during cardiopulmonary bypass by monitoring cerebral autoregulation on postsurgical delirium among older patients & nasal high-flow therapy for newborn infants in special care nurseries; systematic reviews and meta analyses on sodium bicarbonate therapy for critically ill patients with metabolic acidosis & melatonin and melatonin receptor agonists to improve sleep and delirium in the ICU; and observational studies on survival prediction in ICUs based on aggregation of long-term disease history and acute physiology & assessment of anti–factor Xa levels of patients undergoing colorectal surgery given once-daily enoxaparin prophylaxis. There are also guidelines on acute respiratory distress syndrome & classification of cardiogenic shock; narrative reviews on traumatic spinal cord injury & sepsis-associated disseminated intravascular coagulation as well as two series on heart failure, one on improving critical care for Americans with critical illness and another on space medicine. There are also editorials on the pilot SUPERNOVA RCT and awake videolaryngoscope - guided intubation; and commentaries on artificial intelligence in health care & the dangers of the digital age.

Continuing on last week's theme of heart failure, this week's Topic of the Week is based on the Circulation Research series on heart failure, starting with a paper on medical therapy for heart failure caused by ischemic heart disease in tomorrow's Paper of the Day.

If you only have time to read one review article this week, try this one on adjunctive nebulized antibiotics.

Critical Care Reviews Meeting 2020

The big news this week is the addition of the SPICE III trial, investigating dexmedetomidine sedation in mechanically ventilated patients, to the Critical Care Reviews Meeting 2020 programme. Once again we have the best trials of the year so far confirmed for Titanic next January. Registration is open.



Review Articles










CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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