Newsletter 389 | May 26th 2019
Journal Watch | Newsletters | CCR Meeting 2019 | CCR18 Book | Podcast | Hot Articles | Topic of the Week | Reviews | Top 100 Studies | Guidelines | Journals
The latest addition to the #CCR20 programme is the SPICE III trial
Welcome to the 389th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on the effect of targeting mean arterial pressure during cardiopulmonary bypass by monitoring cerebral autoregulation on postsurgical delirium among older patients & nasal high-flow therapy for newborn infants in special care nurseries; systematic reviews and meta analyses on sodium bicarbonate therapy for critically ill patients with metabolic acidosis & melatonin and melatonin receptor agonists to improve sleep and delirium in the ICU; and observational studies on survival prediction in ICUs based on aggregation of long-term disease history and acute physiology & assessment of anti–factor Xa levels of patients undergoing colorectal surgery given once-daily enoxaparin prophylaxis. There are also guidelines on acute respiratory distress syndrome & classification of cardiogenic shock; narrative reviews on traumatic spinal cord injury & sepsis-associated disseminated intravascular coagulation as well as two series on heart failure, one on improving critical care for Americans with critical illness and another on space medicine. There are also editorials on the pilot SUPERNOVA RCT and awake videolaryngoscope - guided intubation; and commentaries on artificial intelligence in health care & the dangers of the digital age.
Continuing on last week's theme of heart failure, this week's Topic of the Week is based on the Circulation Research series on heart failure, starting with a paper on medical therapy for heart failure caused by ischemic heart disease in tomorrow's Paper of the Day.
If you only have time to read one review article this week, try this one on adjunctive nebulized antibiotics.
Critical Care Reviews Meeting 2020
The big news this week is the addition of the SPICE III trial, investigating dexmedetomidine sedation in mechanically ventilated patients, to the Critical Care Reviews Meeting 2020 programme. Once again we have the best trials of the year so far confirmed for Titanic next January. Registration is open.
Research
- Full Text: Brown. Effect of Targeting Mean Arterial Pressure During Cardiopulmonary Bypass by Monitoring Cerebral Autoregulation on Postsurgical Delirium Among Older Patients. A Nested Randomized Clinical Trial. JAMA Surg 2019;epublished May 22nd
- Abstract: Manley. Nasal High-Flow Therapy for Newborn Infants in Special Care Nurseries (HUNTER trial). N Engl J Med 2019;380(21):2031-2040
- Full Text: Salman. Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial. Lancet Neurology 2019;epublished May 22nd
- Abstract: Montassier. Guideline-Based Clinical Assessment Versus Procalcitonin-Guided Antibiotic Use in Pneumonia: A Pragmatic Randomized Trial. Ann Emerg Med 2019;epublished April 11th
- Full Text: Shi. Effect of perioperative administration of dexmedetomidine on delirium after cardiac surgery in elderly patients: a double-blinded, multi-center, randomized study. Clin Interv Aging 2019;14:571-575
- Abstract: Paonessa. Rapid Detection of Methicillin-Resistant Staphylococcus aureus in BAL. A Pilot Randomized Controlled Trial. Chest 2019;155(5):999–1007
- Abstract: Mavros. Fluoroquinolone-based versus β-lactam-based regimens for complicated intra-abdominal infections: a meta-analysis of randomised controlled trials. International Journal of Antimicrobial Agents 2019;53(6):746-754
- Abstract: Zhang. Prophylactic use of exogenous melatonin and melatonin receptor agonists to improve sleep and delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials. Sleep Breath 2019;epublished May 22nd
- Full Text: Nguyen. A scoping review provided a framework for new ways of doing research through mobilizing collective intelligence. J Clin Epidemiol 2019;110:1-11
- Full Text: Wang. Effects of different ascorbic acid doses on the mortality of critically ill patients: a meta-analysis. Annals of Intensive Care 2019;9:58
- Abstract: Fujii. Sodium bicarbonate therapy for critically ill patients with metabolic acidosis: A scoping and a systematic review. J Crit Care 2019;51:184-191
- Abstract: Hamilton. Determinants of Depressive Symptoms at One Year after Intensive Care Unit Discharge in Survivors of ≥7 Days of Mechanical Ventilation: Results from the RECOVER Program - a Secondary Analysis of a Prospective Multi-Centre Cohort Study. Chest 2019;epublished May 15th
- Abstract: Herregodts. Measuring antibiotics in exhaled air in critically ill, non-ventilated patients: A feasibility and proof of concept study. J Critical Care 2019;51:46-50
- Full Text: Pannucci. Assessment of Anti–Factor Xa Levels of Patients Undergoing Colorectal Surgery Given Once-Daily Enoxaparin Prophylaxis. A Clinical Study Examining Enoxaparin Pharmacokinetics. JAMA Surg 2019;epublished May 22nd
- Full Text: Wood. The physiological determinants of near-infrared spectroscopy-derived regional cerebral oxygenation in critically ill adults. Intensive Care Med Exp. 2019;7:23
- Full Text: López. Association between post-procedural hyperoxia and poor functional outcome after mechanical thrombectomy for ischemic stroke: an observational study. Annals of Intensive Care20199:59
- Full Text: Panday. An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial. Critical Care 2019;23:182
- Full Text: Nielsen. Survival prediction in intensive-care units based on aggregation of long-term disease history and acute physiology: a retrospective study of the Danish National Patient Registry and electronic patient records. Lancet Digital Health 2019;1(2):e78–89
Guidelines
- Griffiths. Guidelines on the management of acute respiratory distress syndrome. BMJ Open Respiratory Research 2019;6:e000420
- SCAI clinical expert consensus statement on the classification of cardiogenic shock. Catheter Cardiovasc Interv 2019;epublished May 19th
- Current endovascular strategies for posterior circulation large vessel occlusion stroke: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee. Journal of NeuroInterventional Surgery 2019;epublished May 18th
- Chinese Trauma Surgeon Association for management guidelines of vacuum sealing drainage application in abdominal surgeries—Update and systematic review. Chinese Journal of Traumatology 2019;22(1):1-11
- Saudi Heart Association (SHA) Guidelines for the Management of Heart Failure. Journal of the Saudi Heart Association 2019;epublished May 21st
Review Articles
Neurological
Circulatory
- Patel. Cardiac Ultrasound in the Intensive Care Unit: A Review. Cureus 2019;11(5):e4612
- Amzulescu. Myocardial strain imaging: review of general principles, validation, and sources of discrepancies. Eur Heart J Cardiovasc Imaging 2019;20(6):605–619
- Hausenloy. The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection. Cardiovasc Res. 2019;115(7):1143–1155
- Ziegler. Platelets in cardiac ischaemia/reperfusion injury: a promising therapeutic target. Cardiovasc Res. 2019;115(7):1178-1188
- Burrage. New-Onset Atrial Fibrillation in Adult Patients After Cardiac Surgery. Current Anesthesiology Reports 2019;9(2):174–193
- Curran. Beyond Reperfusion: Acute Ventricular Unloading and Cardioprotection During Myocardial Infarction. J Cardiovasc Transl Res 2019;12(2):95–106
Respiratory
- Finsterer. Neurological Perspectives of Neurogenic Pulmonary Edema. Eur Neurol 2019;81(1-2):94-101
- Niederman. Adjunctive Nebulized Antibiotics: What Is Their Place in ICU Infections? Front Med 2019;6:99
Gastrointestinal
- Sion. Step-up approach for the management of pancreatic necrosis: a review of the literature. Trauma Surgery & Acute Care Open 2019;4:e000308
- Sosa. Abdominal compartment syndrome. Dis Mon 2019;65(1):5-19
Renal
- Mistry. Dialysis disequilibrium syndrome prevention and management. Int J Nephrol Renovasc Dis 2019;12:69-77
- Saez-Rodriguez. Big science and big data in nephrology. Kidney International 2019;epublished March 5th
- Tsuyoshi. Organelle crosstalk in the kidney. Kidney International 2019;epublished March 4th
Haematological
Sepsis
- Worapratya. Septic shock in the ER: diagnostic and management challenges. Open Access Emerg Med 2019;11:77–86
- Nation. Polymyxin Acute Kidney Injury: Dosing and Other Strategies to Reduce Toxicity. Antibiotics 2019;8(1):24
- Avedissian. A Review of the Clinical Pharmacokinetics of Polymyxin B. Antibiotics 2019;8(1):31
- Abdul-Mutakabbir. Teaching an Old Class New Tricks: A Novel Semi-Synthetic Aminoglycoside, Plazomicin. Infectious Diseases and Therapy 2019;8(2):155-170
Paediatrics
- Watkins. Interventions for Pediatric Sepsis and Their Impact on Outcomes: A Brief Review. Healthcare 2019;7(1):2
- Orloff. The Current State of Pediatric Acute Respiratory Distress Syndrome. Pediatric Allergy, Immunology, and Pulmonology 2019;epublished May 15th
Perioperative
- Miclescu. Chronic pain patient and anaesthesia. Rom J Anaesth Intensive Care 2019;26(1):59–66
- Porter. Perioperative ketamine for acute analgesia and beyond. Rom J Anaesth Intensive Care 2019;26(1):67–73
- Pawa. Paravertebral Blocks: Anatomical, Practical, and Future Concepts. Current Anesthesiology Reports 2019;epublished April 11th
- Elgendy. Medical Therapy for Heart Failure Caused by Ischemic Heart Disease. Circ Res 2019;24;124(11):1520-1535
- Repetti. Novel Therapies for Prevention and Early Treatment of Cardiomyopathies. Now and in the Future. Now and in the Future. Circ Res 2019;24;124(11):1536–1550
- Zelt. Medical Therapy for Heart Failure Associated With Pulmonary Hypertension. Circ Res 2019;24;124(11):1551–1567
- Tschöpe. Management of Myocarditis-Related Cardiomyopathy in Adults. Circ Res 2019;24;124(11):1568–1583
- Hussein. Cardiac Implantable Electronic Device Therapy in Heart Failure. Circ Res 2019;24;124(11):1584–1597
- Pfeffer. Heart Failure With Preserved Ejection Fraction In Perspective. Circ Res 2019;24;124(11):1598–1617
- Heallen. Stimulating Cardiogenesis as a Treatment for Heart Failure. Circ Res 2019;24;124(11):1647–1657
- Miller. Use of Ventricular Assist Devices and Heart Transplantation for Advanced Heart Failure. Circ Res 2019;24;124(11):1658–1678
- Pinilla-Vera. Leveraging Signaling Pathways to Treat Heart Failure With Reduced Ejection Fraction. Past, Present, and Future. Circ Res 2019;24;124(11):1618–1632
- Cowgill. Anthracycline and Peripartum Cardiomyopathies. Predictably Unpredictable. Circ Res 2019;24;124(11):1633–1646
- Berliner. New drugs: big changes in conservative heart failure therapy? Eur J Cardiothorac Surg 2019;55(Suppl 1):i3–i10
- Lawin. Change in indication for cardiac resynchronization therapy? Eur J Cardiothorac Surg 2019;55(Suppl 1):i11–i16
- Girdauskas. Minimally invasive mitral valve repair for functional mitral regurgitation. Eur J Cardiothorac Surg 2019;55(Suppl 1):i17–i25Eur J Cardiothorac Surg 2019;55(Suppl 1):i17–i25
- Treede. The role of transcatheter mitral valve therapy in heart failure. Eur J Cardiothorac Surg 2019;55(Suppl 1):i26–i30
- Schramm. Current perspectives on mechanical circulatory support. Eur J Cardiothorac Surg 2019;55(Suppl 1):ii31–i37Eur J Cardiothorac Surg 2019;55(Suppl 1):ii31–i37
- Fuchs. Does the heart transplant have a future? Eur J Cardiothorac Surg 2019;55(Suppl 1):i38–i48
- Castelvecchio. Myocardial reconstruction in ischaemic cardiomyopathy. Eur J Cardiothorac Surg 2019;55(Suppl 1):i49–i56
- Turnbull. Aligning use of intensive care with patient values in the USA: past, present, and future. Lancet Respir Med 2019;epublished May 20th
- Anesi. Understanding irresponsible use of intensive care unit resources in the USA. Lancet Respir Med 2019;epublished May 20th
- Khandelwal. Pragmatic methods to avoid intensive care unit admission when it does not align with patient and family goals. Lancet Respir Med 2019;epublished May 20th
Editorials:
- Nair. Challenges to human spaceflight program: The emerging role of Bioastronautics. Neurol India 2019;67, Suppl S2:167-8
- Agarwal. Human spaceflight from one's own soil. Neurol India 2019;67, Suppl S2:169
- Sharma. Likely challenges facing future astronauts assigned to long duration space flights. Neurol India 2019;67, Suppl S2:170-1
- Andrews. Fallout of space technology for neurosciences on earth. Neurol India 2019;67, Suppl S2:172-3
Commentaries:
- Kandarpa. Human health during space travel: An overview. Neurol India 2019;67, Suppl S2:176-81Kandarpa. Human health during space travel: An overview. Neurol India 2019;67, Suppl S2:176-81
- Frantzidis. Current trends and future perspectives of space neuroscience towards preparation for interplanetary missions. Neurol India 2019;67, Suppl S2:182-7
Reviews:
- Doarn. Health challenges including behavioral problems in long-duration spaceflight. Neurol India 2019;67, Suppl S2:190-5
- Mann. Effects of microgravity and other space stressors in immunosuppression and viral reactivation with potential nervous system involvement. Neurol India 2019;67, Suppl S2:198-203
- Mader. An overview of spaceflight-associated neuro-ocular syndrome (SANS). Neurol India 2019;67, Suppl S2:206-11
- Nday. Neurophysiological changes in simulated microgravity: An animal model. Neurol India 2019;67, Suppl S2:221-6
- Russomano. Space motion sickness: A common neurovestibular dysfunction in microgravity. Neurol India 2019;67, Suppl S2:214-8
Editorials
- Bein. SUPERNOVA: will its energy trigger the formation of a new therapeutic star? Intensive Care Med 2019;epublished May 20th
- Hodzovic. Awake videolaryngoscope - guided intubation - well worth adding to your skill-mix. Rom J Anaesth Intensive Care 2019;26(1):5-7
- Knottnerus. Inadequate comparators produce misleading results – the importance of good comparison practice. J Clin Epidemiol 2019;110:v-vi
Commentaries
- Emanuel. Artificial Intelligence in Health Care. Will the Value Match the Hype? JAMA 2019;epublished May 20th
- Farrell. Systole and Diastole, Strength and Openness. JAMA 2019;321(19):1871-1872
- Mantle. Nasal Decolonisation of MRSA. Antibiotics 2019;8(1):14
- Burki. The dangers of the digital age. Lancet Digital Health 2019;1(2):e61-e62
Correspondence
- Iba. The wind changed direction and the big river still flows: from EUPHRATES to TIGRIS. Journal of Intensive Care 2019;7:31
- Guervilly. Prone positioning and extracorporeal membrane oxygenation for severe acute respiratory distress syndrome: time for a randomized trial? Intensive Care Med 2019;epublished March 9th
Case Reports
- Maïer. Mechanical thrombectomy for a cerebral fat embolism. Intensive Care Med 2019;epublished January 14th
- Islam. A Woman in Her 70s on Anticoagulation With Sudden Shock. Chest 2019;155(5):e123–e126
- Korotun. A 69-Year-Old Man Presented With Abdominal Pain and Dark, Tarry Stools. Chest 2019;155(5):e127–e129
- Shostak. Progressive Tubular Lung Mass in Asymptomatic Young Woman. Chest 2019;155(5):e131–e135
- Henson. A 76-Year-Old Woman With Incidental Right Middle Lobe Atelectasis. Chest 2019;155(5):e137–e140
- Millar. A 42-Year-Old Man With Shortness of Breath, Fever, and Pleural Effusions. Chest 2019;155(5):e141–e144
- Bulnes. A 45-Year-Old Man With Progressive Dyspnea, Chest Pain, and Hypereosinophilia. Chest 2019;155(5):e149–e154
CCH Journal
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
Rob
Supported by the Health Research Board
