CCR-Newsletter-BannerNewsletter 375  |  February 19th 2019

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Welcome to the 375th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are two randomised controlled stroke trials on blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke & minimally invasive surgery with thrombolysis in intracerebral haemorrhage; systematic reviews and meta analyses on fever control in critically ill adultstranexamic acid in cerebral hemorrhage; and observational studies on the association of left ventricular ejection fraction with mortality after elective noncardiac surgery & sepsis-associated mortality in US acute care hospitals There are also guidelines on the role of the cardiac cath lab in the management of patients with out-of-hospital cardiac arrest & antiarrhythmic drugs for cardiac arrest; narrative reviews on septic shock & mobilising patients on cardiac extracorporeal life support; editorials on why bleeding trauma patients are still dying & decisions on withholding "non-beneficial" intensive care; and commentaries on the future of scientific publishing & permissive hypotensive resuscitation in traumatic hemorrhagic shock. There is also an excellent free book on sepsis management in resource-limited settings.

This week's Topic of the Week is spinal cord injury, starting with a paper on critical care for acute spinal cord injury in the setting of polytrauma in yesterday's Paper of the Day.

If you only have time to read one review article this week, try this one on heterogeneity and variability in pressure autoregulation of organ blood flow - lessons learned over 100+ years.



Review Articles







CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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