Newsletter 351 | September 2nd 2018
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2nd World Sepsis Congress Live & Free Online
Welcome to the 351st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are two randomised controlled trials comparing supraglottic airway use with tracheal intubbation in out-of-hospital cardiac arrest; a systematic review and meta analysis on video vs. direct laryngoscopy for emergency intubation; and an observational study on major trauma in the NHS (England) 2008–17. There are also guidelines on myocardial revascularization, arterial hypertension, & heart failure, as well as narrative reviews on oxygen treatment in ICU & ED (timely with the results of the pilot phase of ICU-ROX just published), transfusion strategies in damage control resuscitation, & cardiorenal syndrome; plus commentaries on ECMO & Takotsubo cardiomyopathy as a variant of acute MI.
The correspondence on both the ADRENAL and APPROCCHSS trials was published this week. Additionally, in an unusual move, the CLOVERS trial has been called into question, as an American watchdog group calls for NIH to halt ‘dangerous’ study of sepsis treatment.
This week's Topic of the Week is based on a series of papers published in Pediatric Critical Care Medcine on end-of-life care, starting with a paper on the logistics of withdrawal of life-sustaining therapies in PICU in tomorrow's Paper of the Day.
If you only have time to read one review article this week, try this one on carbapenem-resistant Gram-negative infections.
In meeting news, the 2nd World Sepsis Congress takes place later this week. This unique event is an online conference which is free to watch. With many of the finest researchers in critical care taking part, this is highly recommended. Turning to #CCR19, the annual honorary John Hinds Trauma Lecture at the Critical Care Reviews Meeting 2019 will be delivered by Prof Maureen McCunn, Professor of Anaesthesiology at University of Maryland School of Medicine. Her talk is entitled: "A Culture of Excellence - R Adams Cowley Shock Trauma Center".
Research
- Full Text: Wang. Effect of a Strategy of Initial Laryngeal Tube Insertion vs Endotracheal Intubation on 72-Hour Survival in Adults With Out-of-Hospital Cardiac ArrestA Randomized Clinical Trial. JAMA 2018;320(8):769-778
- Abstract: Benger. Effect of a Strategy of a Supraglottic Airway Device vs Tracheal Intubation During Out-of-Hospital Cardiac Arrest on Functional OutcomeThe AIRWAYS-2 Randomized Clinical Trial. JAMA 2018;320(8):779-791
- Full Text: Iversen. Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis. N Engl J Med 2018;epublished August 25th
- Abstract: Ydemann. Intraoperative clonidine for prevention of postoperative agitation in children anaesthetised with sevoflurane (PREVENT AGITATION): a randomised, placebo-controlled, double-blind trial. Lancet Child Adolesc Health 2018;2(1):15-24
- Full Text: Andrews. Therapeutic hypothermia to reduce intracranial pressure after traumatic brain injury: the Eurotherm3235 RCT. Health Technol Assess 2018;22(45):1-134
- Abstract: Darvall. Frailty indexes in perioperative and critical care: A systematic review. Arch Gerontol Geriatr 2018;79:88-96
- Full Text: Rombey. Video Versus Direct Laryngoscopy for Inpatient Emergency Intubation in Adults. A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Dtsch Arztebl Int 2018;115(26):437-44
- Abstract: Hernandez. Cardiac Resynchronization Therapy in Inotrope-Dependent Heart Failure Patients. A Systematic Review and Meta-Analysis. JACC: Heart Failure 2018;6(9):734-742
- Abstract: Moran. Changing the System - Major Trauma Patients and Their Outcomes in the NHS (England) 2008–17. EClinicalMedicine 2018;epublished August 5th
- Abstract: Zelop. Characteristics and Outcomes of Maternal Cardiac Arrest: A descriptive analysis of Get with the Guidelines data. Resuscitation 2018;epublished August 28th
- Abstract: Fatuzzo. Does continuous EEG influence prognosis in patients after cardiac arrest? Resuscitation 2018;epublished August 25th
- Couper. Mechanical versus manual chest compressions in the treatment of in-hospital cardiac arrest patients in a non-shockable rhythm: a randomised controlled feasibility trial (COMPRESS-RCT). Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2018;26:70
- Mauri. Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: study protocol for a pilot randomized controlled trial, the PROTECTION trial. Trials 2018;19(1):460
Guidelines
- 2018 ESC/EACTS Guidelines on myocardial revascularization. European Journal of Cardio-Thoracic Surgery 2018;ezy289
- 2018 ESC/ESH Guidelines for the management of arterial hypertension. European Heart Journal 2018;epublished August 25th
- National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Guidelines for the Prevention, Detection, and Management of Heart Failure in Australia 2018. Heart, Lung and Circulation 2018;27:1123–1208
- National Heart Foundation of Australia and the Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Diagnosis and Management of Atrial Fibrillation 2018. Heart, Lung and Circulation 2018;27:1209–1266
Review Articles
Neurological
- Heckmann. Neuro-Ophthalmology at the bedside: A clinical guide. J Neurosci Rural Pract 2018;9:561-73
Circulatory
- Zannad. Cardiorenal Syndrome Revisited. Circulation 2018;138:929-944
- Möller. Ventricular arrhythmias in patients with Takotsubo syndrome. J Arrhythmia 2018;34(4):369-375
- Döring. The Diagnosis and Treatment of Pacemaker-Associated Infection. Dtsch Arztebl Int 2018;115(26):445-52
- Smid. Cardiogenic Causes of Fever. Dtsch Arztebl Int 2018;115(12):193-9
Respiratory
Renal
Haematological
Sepsis
- Chernyadyev. Fournier's Gangrene: Literature Review and Clinical Cases. Urol Int 2018;101(1):91–97
- Fritzenwanker. Treatment Options for Carbapenem-Resistant Gram-Negative Infections. Dtsch Arztebl Int 2018;115(20-21):345-52
- Kiu. An update on the human and animal enteric pathogen Clostridium perfringens. Emerging Microbes & Infections 2018;7:141
Trauma
Immunology
- Ring. Adrenaline in the Acute Treatment of Anaphylaxis. Dtsch Arztebl Int 2018;115(31-32):528-534
- Böhm. Drug Hypersensitivity: Diagnosis, Genetics, and Prevention. Dtsch Arztebl Int 2018;115(29-30):501-12Böhm. Drug Hypersensitivity: Diagnosis, Genetics, and Prevention. Dtsch Arztebl Int 2018;115(29-30):501-12
- Lerkvaleekul. Macrophage activation syndrome: early diagnosis is key. Open Access Rheumatology: Research and Reviews 2018:10 117–128
- Bortolotti. Inflammasomes in Tissue Damages and Immune Disorders After Trauma. Front Immunol 2018;9:1900
Toxicology
Paediatrics
Pediatric Critical Care Medicine Series on "Paediatric End-of-Life Care"
- Nakagawa. Organ Donation Following Neurologic and Circulatory Determination of Death. Ped Crit Care Med 2018;19(8S):S26–S32
- Dryden-Palmer. Logistics of Withdrawal of Life-Sustaining Therapies in PICU. Ped Crit Care Med 2018;19(8S):S19–S25
- Lewis-Newby. When a Child Dies in the PICU Despite Ongoing Life Support. Ped Crit Care Med 2018;19(8S):S33–S40
- Kang. Compassionate Discharges From the PICU. Ped Crit Care Med 2018;19(8S):S41–S47
- Grosek. Notes on the Development of the Slovenian Ethical Recommendations for Decision-Making on Treatment and Palliative Care of Patients at the End of Life in Intensive Care Medicine. Ped Crit Care Med 2018;19(8S):S48–S52
- October. Caring for Parents After the Death of a Child. Ped Crit Care Med 2018;19(8S):S61–S68
- Griffiths. Learning From Investigation After Death. Ped Crit Care Med 2018;19(8S):S72–S78
- Dryden-Palmer. Care for Dying Children and Their Families in the PICU: Promoting Clinician Education, Support, and Resilience. Ped Crit Care Med 2018;19(8S):S79–S85
- Morrison. Integrating Palliative Care Into the ICU: From Core Competency to Consultative Expertise. Ped Crit Care Med 2018;19(8S):S86–S91
- Gilleland. Discussing Death as a Possible Outcome of PICU Care. Ped Crit Care Med 2018;19(8S):S4–S9
- Kirsch. Ethical, Cultural, Social, and Individual Considerations Prior to Transition to Limitation or Withdrawal of Life-Sustaining Therapies. Ped Crit Care Med 2018;19(8S):S10–S18
Miscellaneous
- Matsunaga. Fibrinogen for the management of critical obstetric hemorrhage. J Obstet Gynaecol Res 2018;epublished August 28th
- Rosendale. Acute Clinical Care for Transgender Patients. A Review. JAMA Intern Med 2018;epublished August 27th
Commentaries
- Mi. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. N Engl J Med 2018;379:884-887
- Geller. Critical Care Cardiology. Implementing a Training Paradigm. JACC 2018;72(10):1171-1175
- Sharkey. The Case for Takotsubo Cardiomyopathy (Syndrome) as a Variant of Acute Myocardial Infarction. Circulation 2018;138:855–857
- Rubin. Addressing Barriers to Inclusion of Pregnant Women in Clinical Trials. JAMA 2018;320(8):742-744
- Bohn. Investigations After Death in Children. Ped Crit Care Med 2018;19(8S):S69–S71
- Hinton. Deep Learning—A Technology With the Potential to Transform Health Care. JAMA 2018;epublished August 30th
- Naylor. On the Prospects for a (Deep) Learning Health Care System. JAMA 2018;epublished August 30th
Miscellaneous
- Various. Glucocorticoids with or without Fludrocortisone in Septic Shock. N Engl J Med 2018;379(9):893-896
- Argent. Death and Dying Over 30 Years in the ICU: Personal Reflection. Ped Crit Care Med 2018;19(8S):S53–S54
- Cox. Death and Dying 1987–2017: The Destination Is the Same, the Journey Is Different. Ped Crit Care Med 2018;19(8S):S55–S56
- Butt. Death and Dying in the ICU: Personal Reflection of 30 Years’ Experience. Ped Crit Care Med 2018;19(8S):S57–S58
- Piva. Modes of Death and the Dying Process in Brazilian PICU Over the Last 30 Years: Personal Reflections. Ped Crit Care Med 2018;19(8S):S59–S60
- Dirks. Cullen’s Sign in Necrotizing Pancreatitis. Dtsch Arztebl Int 2018;115(20-21):353
- Bösche. A 21-Year-Old Man With Coronary Artery Dissection After Blunt Trauma to the Chest. Dtsch Arztebl Int 2018;115(12):209
- Laqmani. Sudden Dyspnea in a Liver Transplant Recipient. Dtsch Arztebl Int 2018;115(18):323
- Christ. Chest Pain Due to Pacemaker Lead Perforation. Dtsch Arztebl Int 2018;115(14):242
- Drinhaus. Heart in the Wrong Place: Cardiac Herniation after Pulmonectomy. Dtsch Arztebl Int 2018;115(14):249
- Arbiol. Dangerous ECG in the Ward. Circulation 2018;138:947-950
- Begley. Watchdog group calls for NIH to halt ‘dangerous’ study of sepsis treatment. STAT News 2018;epublished August 28thWatchdog group calls for NIH to halt ‘dangerous’ study of sepsis treatment. STAT News 2018;epublished August 28th
- Charuchandra. Indian Government Aims to Take Down Predatory Journals. Scientist 2018;epublished August 29th
Meetings
CCR19
Belfast, 18-19th January 2019
SMACC Sydney
Sydney, 26-29th March 2019
Women in ICM
London, February 6th
CCH Journal
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
Rob
Supported by the Health Research Board
