Newsletter 334  |  May 7^th 2018

Journal Watch  |  Newsletters  |  CCR Meeting 2019  |  CCR18 Book |  Podcast  |  Hot Articles  |  Topic of the Week  |  Reviews  |  Top 100 Studies  |  Guidelines  |  Journals

European General Data Protection Regulation (GDPR)

The European General Data Protection Regulation comes into force on May 25th 2018 and has major implications worldwide. This is why you have been receiving emails from various companies asking you to agree to updated terms and conditions. European citizens now have multiple digital rights over their personal details, including the right to be asked to provide consent for the storage of personal details, the right to be asked to provide consent to be contacted, the right to see the personal information stored, the right to know who this information is shared with (consent is also required for sharing), the right to be contacted should a significant data breach occur and the right to be forgotten, including having all personal details permanently removed from a database. All of these changes must be prospectively acknowledged by the user and cannot be presumed to have occurred. The onus rests with the database holders (i.e. Critical Care Reviews) to be able to demonstrate consent has been obtained. Fines for non-compliance with this can reach €20 million. As a result, we have updated our privacy policy accordingly........

The current newsletter database will be deleted after next week's newsletter. If you wish to continue to receive the newsletter by email you will need to resubscribe after May 14th. You can resubscribe now, but need to use a different email address. If you wish to use the same email address, just resubscribe after May 14th. Anyone who has subscribed after May 2nd 2018 has already gone through this new process and does not need to resubscribe. The newsletter is freely available on the website at the same time as it is emailed to all subscribers every week, so there is no need to resubscribe if you do not wish to have your details on the CCR database. Please see our updated Privacy Policy if you wish to read more or email me if you need more information. 

Staying on this theme, this week's Topic of the Week is a broad look at data, starting with a paper on “Big Data” in the ICU in tomorrow's Paper of the Day.

Research

+ - Randomised Controlled Trials Click to collapse

• Abstract:  Fetterplace. Targeted Full Energy and Protein Delivery in Critically Ill Patients: A Pilot Randomized Controlled Trial (FEED Trial). JPEN J Parenter Enteral Nutr 2018;epublished April 27th
• Abstract:  Durrmeyer. Effect of Atropine With Propofol vs Atropine With Atracurium and Sufentanil on Oxygen Desaturation in Neonates Requiring Nonemergency IntubationA Randomized Clinical Trial (PRETTINEO Trial). JAMA 2018;319(17):1790-1801
• Abstract:  Skrobik. Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial. Am J Respir Crit Care Med 2018;197(9):1147–1156
• Full Text:  Ahn. Sodium bicarbonate on severe metabolic acidosis during prolonged cardiopulmonary resuscitation: a double-blind, randomized, placebo-controlled pilot study. J Thorac Dis 2018;10(4):2295-2302

+ - Systematic Reviews & Meta Analyses Click to collapse

• Abstract:  Anthon. No firm evidence that lack of blinding affects estimates of mortality in randomised clinical trials of intensive care interventions: a systematic review and meta-analysis. JCE 2018;epublished April 26th
• Full Text:  Tena. Levosimendan versus placebo in cardiac surgery: a systematic review and meta-analysis. Interact Cardiovasc Thorac Surg 2018;epublished April 30th
• Abstract:  Heinrichs. The impact of hyperoxia on outcomes after cardiac surgery: a systematic review and narrative synthesis. Can J Anaesth 2018;epublished May 2nd
• Abstract:  Saillard. Critically ill allogenic HSCT patients in the intensive care unit: a systematic review and meta-analysis of prognostic factors of mortality. Bone Marrow Transplant 2018;epublished April 27th
• Abstract:  Sardo. Nitric Oxide in Cardiac Surgery: A Meta-Analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth 2018;epublished April 24th
• Full Text:  Fuke. Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis. BMJ Open 2018;8:e019998

+ - Observational Studies Click to collapse

• Abstract:  Barbaro. Does Extracorporeal Membrane Oxygenation Improve Survival in Pediatric Acute Respiratory Failure? Am J Respir Crit Care Med 2018;197(9):1177–1186
• Abstract:  Ferrante. Pre–Intensive Care Unit Cognitive Status, Subsequent Disability, and New Nursing Home Admission among Critically Ill Older Adults. Annals ATS 2018;15(5):622–629
• Full Text:  Goto. Relationship Between Emergency Medical Services Response Time and Bystander Intervention in Patients With Out‐of‐Hospital Cardiac Arrest. J Am Heart Assoc 2018;7:e007568
  • Editorial:  Bobrow. Time to Compress the Time to First Compression. J Am Heart Assoc 2018;7:e009247
• Abstract:  Raghunathan. Early Blood Transfusions in Sepsis: Unchanged Survival and Increased Costs. Am J Crit Care 2018;27(3):205–211
• Full Text:  Boshuizen. Iron metabolism in critically ill patients developing anemia of inflammation: a case control study. Ann Intensive Care 2018;8(1):56
• Abstract:  Shoamanesh. Cerebral Microbleeds and the Effect of Intensive Blood Pressure Reduction on Hematoma Expansion and Functional Outcomes: A Secondary Analysis of the ATACH-2 Randomized Clinical Trial. JAMA Neurol 2018;epublished April 16th
• Full Text:  Houston. Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial. Critical Care 2018;22:119

+ - Cochrane Reviews Click to collapse

• Lui. Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth. Cochrane Database of Systematic Reviews 2018, Issue 5. Art. No.: CD010239
• Estcourt. Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia. Cochrane Database of Systematic Reviews 2018, Issue 4. Art. No.: CD011980
• Kahn. Interventions for implementation of thromboprophylaxis in hospitalized patients at risk for venous thromboembolism. Cochrane Database of Systematic Reviews 2018, Issue 4. Art. No.: CD008201

+ - Protocols Click to collapse

• Le Cornec. Is intravenously administered, subdissociative-dose KETAmine non-inferior to MORPHine for prehospital analgesia (the KETAMORPH study): study protocol for a randomized controlled trial. Trials 2018;19(1):260
• Koda. Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury. BMJ Open 2018;8:e019083

Guidelines

• Kiehl. Consensus statement for cancer patients requiring intensive care support. Annals of Hematology 2018;epublished April 27th
• Comprehensive in-hospital monitoring in acute heart failure: applications for clinical practice and future directions for research. A statement from the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur J Heart Fail 2018;epublished April 30th

Review Articles

+ - Clinical Click to collapse

Neurological

• Kengne. Hyponatremia and the Brain. Kidney Int Rep 2018;3(1):24–35

Circulatory

• De Backer. Alternatives to the Swan–Ganz catheter. Intensive Care Med 2018;epublished May 3rd
• Ehrman. Pathophysiology, echocardiographic evaluation, biomarker findings, and prognostic implications of septic cardiomyopathy: a review of the literature. Critical Care 2018;22:112
• Young. Hypertrophic cardiomyopathy: A complex disease. Cleveland Clinic Journal of Medicine 2018;85(5):399-411
• Fudulu. Corticosteroids in Pediatric Heart Surgery: Myth or Reality. Front Pediatr 2018;6:112
• Aneman. Advances in critical care management of patients undergoing cardiac surgery. Intensive Care Med 2018;epublished April 30th

Respiratory

• Pan. Acute Respiratory Distress Syndrome: Challenge for Diagnosis and Therapy. Chin Med J 2018;131:1220-4
• Zhou. Halogen Inhalation-Induced Lung Injury and Acute Respiratory Distress Syndrome. Chin Med J 2018;131:1214-9
• Gust. Single-lung and double-lung transplantation: technique and tips. J Thorac Dis 2018;10(4):2508-2518

Gastrointestinal

• Ladopoulos. Gastrointestinal dysmotility in critically ill patients. Annals of Gastroenterology 2018;31:1-9

Hepatobiliary

•  Mantaka. Portal vein thrombosis in cirrhosis: diagnosis, natural history, and therapeutic challenges. Ann Gastroenterol 2018;31(3):315-329

Renal

• Shah. Using Electrolyte Free Water Balance to Rationalize and Treat Dysnatremias. Front Med 2018;epublished April 23rd
• Zhang. Gut–kidney crosstalk in septic acute kidney injury. Critical Care 2018;22:117
• Abuelo. Treatment of Severe Hyperkalemia: Confronting 4 Fallacies. Kidney Int Rep 2018;3(1):47–55
• Rao. Acute Kidney Injury in Pregnancy: The Changing Landscape for the 21st Century. Kidney Int Rep 2018;3(2):247–257

Burns

• Al-Tarrah. Vitamin D status and its influence on outcomes following major burn injury and critical illness. Burns & Trauma 2018;6:11
• King. Body image in paediatric burns: a review. Burns & Trauma 2018;6:12
• Boyce. Tissue engineering of skin and regenerative medicine for wound care. Burns & Trauma 2018;6:4
• He. Bioprinting of skin constructs for wound healing. Burns & Trauma 2018;6:5

+ - Non-Clinical Click to collapse

• Textoris. Data-driving methods: More than merely trendy buzzwords? Annals of Intensive Care 2018;8:58

+ - Pre-Clinical Click to collapse

• Chen. Molecular Mechanisms of Ventilator-Induced Lung Injury. Chin Med J 2018;131:1225-31hen. Molecular Mechanisms of Ventilator-Induced Lung Injury. Chin Med J 2018;131:1225-31

Editorials

• Yin. Pharmacotherapy for Adult Patients with Acute Respiratory Distress Syndrome. Chin Med J 2018;131:1138-41
• Wu. Contrast-Enhanced Ultrasonography: A Promising Method for Blood Flow and Perfusion Evaluation in Critically Ill Patients. Chin Med J 2018;131:1135-7
• Lange. Prompt admission to the ICU: an instrument to improve mortality for deteriorating ward patients. Intensive Care Med 2018;epublished April 28th
• Aygencel. Does immunosuppression affect the course of septic shock? J Thorac Dis 2018;10(Suppl 9):S1119-S1121
• Marik. Steroids for sepsis: yes, no or maybe. J Thorac Dis 2018;10(Suppl 9):S1070-S1073
• Mireles-Cabodevila. APRV for ARDS: the complexities of a mode and how it affects even the best trials. J Thorac Dis 2018;10(Suppl 9):S1058-S1063
• Cutuli. Improving the care for elective surgical patients: post-operative ICU admission and outcome. J Thorac Dis 2018;10(Suppl 9):S1047-S1049
• Hepokoski. Prone positioning in acute respiratory distress syndrome: why aren’t we using it more? J Thorac Dis 2018;10(Suppl 9):S1020-S1024
• Singer. Editorial on “enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2)”. J Thorac Dis 2018;10(Suppl 9):S974-S977
• Di Tommaso. Endovascular treatment for chronic type B aortic dissection: current opinions. J Thorac Dis 2018;10(Suppl 9):S978-S982
• Margaryan. Individualized clopidogrel suspension strategy coronary artery bypass surgery: what is the best choice? J Thorac Dis 2018;10(Suppl 9):S969-S971

Commentaries

• Su. Personalized Critical Hemodynamic Therapy Concept for Shock Resuscitation. Chin Med J 2018;131:1240-3
• Borthwick. The role of the pharmacist in the intensive care unit. JICS 2018;epublished April 23rd
• Voelker. Taking a Closer Look at the Biomarker Test for Mild Traumatic Brain Injury. JAMA 2018;epublished May 2nd
• Darmon. What’s new in cardiorenal syndrome? Intensive Care Med 2018;epublished April 26th
• McLean. Does this patient have takotsubo syndrome? Intensive Care Med 2018;epublished April 27th
• Dessap. Cardiac tamponade. Intensive Care Med 2018;epublished April 27th
• Brown. The ten things you need to know about long-term outcomes following paediatric cardiac surgery. Intensive Care Med 2018;epublished April 25th
• Reilly. The Best Medical Care in the World. N Engl J Med 2018; 378:1741-1743
• Morrison. Fifty Years of Pediatric Critical Care: An Interview With Dr. Jack Downes. Ped Crit Care Med 2018;19(5):e259–e262
• Suffredini. Management of Antiretrovirals in Critically Ill Patients: Great Progress But Potential Pitfalls. Crit Care Med 2018;46(5):663–665
• Bruce. Legislating Medicine: The Need for Evidence, Argument, and Alliance. Crit Care Med 2018;46(5):788-790

Miscellaneous

+ - Correspondence Click to collapse

• McKown. Best PEEP trials are dependent on tidal volume. Critical Care 2018;22:115
• Various. Angiography with Sodium Bicarbonate and Acetylcysteine. N Engl J Med 2018; 378:1748-1749

+ - Case Reports Click to collapse

• Li. Multidisciplinary team approach on a case of bilateral tension pneumothorax. J Thorac Dis 2018;10(4):2528-2536

Meetings

CCR19

Belfast, 18-19th January 2019

SMACC Sydney

Sydney, 26-29th March 2019

Women in ICM

London, February 6th

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week

Rob

Supported by the Health Research Board