Peter Hjortrup discusses the CLASSIC Trial at CCR17
Welcome to the 273rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. The highlights of this week's edition are randomised controlled trials on liberal versus restrictive transfusion in critically ill oncologic patients and inhaled corticosteroid and beta agonist therapy in patients at risk of ARDS; a follow up study from the PermiT Trial; a European Society of Anaesthesiology guideline on antibiotic therapy in the critically ill; as well as reviews on burns, informed consent and gender parity in critical care.
There are another two talks out from the Critical Care Reviews Meeting 2017. Peter Hjortrup discusses the CLASSIC trial and Gonzalo Hernandez examines his high flow nasal oxygen post extubation trial.
- Abstract: Bergamin. Liberal Versus Restrictive Transfusion Strategy in Critically Ill Oncologic Patients: The Transfusion Requirements in Critically Ill Oncologic Patients Randomized Controlled Trial. Crit Care Med 2017;epublished February 24th
- Abstract: Festic. Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome. Crit Care Med 2017;epuvblished February 24th
- Abstract: Williamson. Occupational therapy for delirium management in elderly patients without mechanical ventilation in an intensive care unit: A pilot randomized clinical trial. J Crit Care 2017;epublished February 23rd
- Abstract: Kwiatkowski. Peritoneal Dialysis vs Furosemide for Prevention of Fluid Overload in Infants After Cardiac Surgery: A Randomized Clinical Trial. JAMA Pediatr 2017;epublished February 20th
- Abstract: Engstrøm. Effect of Ischemic Postconditioning During Primary Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction: A Randomized Clinical Trial. JAMA Cardiol 2017;epublished March 1st
- Full Text: Chuang. Instantaneous responses to high-frequency chest wall oscillation in patients with acute pneumonic respiratory failure receiving mechanical ventilation: A randomized controlled study. Medicine (Baltimore) 2017;96(9):e5912
- Abstract: Snowdon. Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial. PLoS Med 2017;14(2):e1002248
- Full Text: Brain. Non anti-coagulant factors associated with filter life in continuous renal replacement therapy (CRRT): a systematic review and meta-analysis. BMC Nephrology 2017;epublished February 20th
- Abstract: Cai. The influence of tracheostomy timing on outcomes in trauma patients: A meta-analysis. Injury 2017;epublished February 22nd
- Abstract: Meade. Severity of Hypoxemia and Effect of High Frequency Oscillatory Ventilation in ARDS. Am J Respir Crit Care Med 2017;epublished February 28th
- Full Text: Bhatt. Early versus late initiation of renal replacement therapy in patients with acute kidney injury-a systematic review & meta-analysis of randomized controlled trials. BMC Nephrol 2017;18(1):78
- Abstract: Solé-Lleonart. Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults: A Systematic Review and Meta-analysis. Anesthesiology 2017;epublished March 1st
- Abstract: Kuriyama. Prophylactic corticosteroids for prevention of post-extubation stridor and reintubation in adults: a systematic review and meta-analysis. Chest 2017;epublished March 2nd
- Abstract: de Crescenzo. Prehospital Hypertonic Fluid Resuscitation for Trauma Patients: a Systematic Review and Meta-analysis. J Trauma Acute Care Surg 2017;epublished March 2nd
- Abstract: Arabi. Permissive Underfeeding or Standard Enteral Feeding in High– and Low–Nutritional-Risk Critically Ill Adults. Post Hoc Analysis of the PermiT Trial. Am J Respir Crit Care Med 2017;195(5):652-662
- Abstract: Joshi. Difficult Airway Characteristics Associated with First-Attempt Failure at Intubation Using Video Laryngoscopy in the Intensive Care Unit. ATS 2017;14(3)
- Abstract: Villar. A Quantile Analysis of Plateau and Driving Pressures: Effects on Mortality in Patients With Acute Respiratory Distress Syndrome Receiving Lung-Protective Ventilation. Crit Care Med 2017;epublished March 1st
- Abstract: Donnelly. Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study. Lancet Infect Dis 2017;epublished March 3rd
- Abstract: Russo. Assessing the Risks Associated with MRI in Patients with a Pacemaker or Defibrillator. N Engl J Med 2017;376:755-764
- Nelson. Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. Cochrane Database of Systematic Reviews 2017, Issue 3. Art. No.: CD004610
- Chevret. Plasma exchange for Guillain-Barré syndrome. Cochrane Database of Systematic Reviews 2017, Issue 2. Art. No.: CD001798
- Dalal. Probiotics for people with hepatic encephalopathy. Cochrane Database of Systematic Reviews 2017, Issue 2. Art. No.: CD008716
- Gawlytta. Internet-based cognitive–behavioural writing therapy for reducing post-traumatic stress after intensive care for sepsis in patients and their spouses (REPAIR): study protocol for a randomised-controlled trial. BMJ Open 2017;7:e014363
- Rocha. Thromboelastometry versus standard coagulation tests versus restrictive protocol to guide blood transfusion prior to central venous catheterization in cirrhosis: study protocol for a randomized controlled trial. Trials 2017;18:85
- Jones. Brain Monitoring in Critically Neurologically Impaired Patients. Int J Mol Sci 2017;(1):43
- Reis. Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury. Int J Mol Sci 2017;18(1):129
- Sommer. Ischemic stroke: experimental models and reality. Acta Neuropathol 2017;133(2):245–261
- Schurman. Endocannabinoids: A Promising Impact for Traumatic Brain Injury. Front Pharmacol 2017;8:69
- Borne. Implantable Cardioverter‐Defibrillators for Secondary Prevention of Sudden Cardiac Death: A Review. J Am Heart Assoc 2017;6:e005515
- Leclerc. Cardiopulmonary exercise testing: A contemporary and versatile clinical tool. Cleveland Clinic Journal of Medicine 2017;84(2):161-168
- Park. A review of current status of living donor liver transplantation. Hepatobiliary Surg Nutr 2016;5(2):107-117
- Bainbridge. Current evidence on fast track cardiac recovery management. Eur Heart J Suppl 2017;19(suppl_A):A3-A7
- Wilson. Duration of dual antiplatelet therapy in acute coronary syndrome. Heart 2017;epublished March 1st
- Ranucci. Anaesthesia and cardiopulmonary bypass aspects of fast track. Eur Heart J Suppl 2017;19(suppl_A):A15-A17
- Schreiber. High flow nasal cannula oxygen therapy, work in progress in respiratory critical care. Minerva Medica 2016;107(6 Suppl 1):14-20
- Bajaj. Introduction and setting the scene: New nomenclature of hepatic encephalopathy and American Association for the Study of Liver Diseases/European Association for the Study of the Liver guidelines. Clinical Liver Disease 2017;9:48–51
- Stocker. Small but mighty: Platelets as central effectors of host defense. Thromb Haemost 2017;epublished February 16th
- Nielson. Burns: Pathophysiology of Systemic Complications and Current Management. J Burn Care Res 2017;38(1):e469–e481
- Carli. Preoperative functional assessment and optimization in surgical patient: changing the paradigm. Minerva Anestesiologica 2017;83(2):214-8
- Chaggar. The future of general anaesthesia in obstetrics. BJA Educ 2017;17(3):79-83
- Chew. Improving perioperative outcome: time to update protocols. European Journal of Anaesthesiology 2017;34(4):185-188
- Batt. Mechanism of ICU-acquired weakness: muscle contractility in critical illness. Intensive Care Med 2017;epublished March 3rd
- Anonymous. Research matters: challenges of replication. Lancet 2017;389(10072):882
- Related Article: Mogil. No publication without confirmation. Nature 2017;542:409–411
- Rifai. Bleeding esophageal varices: Who should receive a shunt? Cleveland Clinic Journal of Medicine 2017;84(3):199-201
- Abbasi. Israeli Physician Salman Zarka, MD: Caring for Syrian Patients Is Our Duty. JAMA 2017;epublished March 1st
- Raffa. Migrants crossing the Mediterranean Sea: an opportunity or a duty?. Intensive Care Med 2017;epublished March 2nd
- Ciarleglio. Sample size determination for a binary response in a superiority clinical trial using a hybrid classical and Bayesian procedure. Trials 2017;18:83
- Mbuagbaw. Challenges to complete and useful data sharing. Trials 2017;18:71
There are just 5 months left unit Das SMACC and all tickets have now been sold for the main conference. If you are interested in attending the workshops, there are a very small number of tickets left for the Hardcore Intensive Care workshop being organised by Steve Mathieu and Sarah Yong. With a superb international faculty, this half-day event will address your burning critical care questions.
(Image from Chensiyuan via Wikipedia)
The Critical Care Symposium (CCS) was initiated to satisfy the purpose of creating a world-class environment for medical enrichment in the North of England, particularly in Manchester. It was envisioned as a common informal platform wherein professionals from the field of critical care could provide and enhance the knowledge of delegates on current practices and related fields of interest.
Now in its 14th year, the annual conference regularly has renowned speakers from around the world and attracts more than 400 delegates. And this year is no different. In recent years a parallel course on ultrasound has been conducted alongside the conference that provides ample hand-on experience over two days. This year will host the 7th Ultrasound in Acute Care. For more information please visit http://critcaresymposium.co.uk.
The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.
The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring. A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.
Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week