• Abstract:  Gordon. Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock. The VANISH Randomized Clinical Trial. JAMA 2016;316(5):509-518
• Full Text:  Hwang. A Randomized Controlled Trial of Compression Rates during Cardiopulmonary Resuscitation. J Korean Med Sci 2016;31(9):1491-1498  {ht @jlvincen)
• Abstract:  Denault. A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients. Can J Anesth 2016;epublished July 28th
• Full Text:  Connelly. Thrombelastography-Based Dosing of Enoxaparin for Thromboprophylaxis in Trauma and Surgical Patients: A Randomized Clinical Trial. JAMA Surg 2016;epublished August 3rd

• Abstract:  O'Connell. The Use of Intermittent Pneumatic Compression in Orthopedic and Neurosurgical Postoperative Patients: A Systematic Review and Meta-analysis. Ann Surg 2016;263:888-889
• Abstract:  Cournoyer. Near-infrared Spectroscopy Monitoring During Cardiac Arrest: A Systematic Review and Meta-analysis. Acad Emerg Med 2016;23(8):1553-2712
• Abstract:  Xu. Timing of initiation of renal replacement therapy for acute kidney injury: a systematic review and meta-analysis of randomized-controlled trials. Clin Exp Nephrol 2016;epublished August 2nd
• Full Text:  Mistry. Corticosteroids in the Management of Hyponatremia, Hypovolemia, and Vasospasm in Subarachnoid Hemorrhage: A Meta-Analysis. Cerebrovasc Dis 2016;42:263-271

• Abstract:  Han. Influence of Daily Fluid Balance prior to Continuous Renal Replacement Therapy on Outcomes in Critically Ill Patients. J Korean Med Sci 2016;31(8):1337-44
• Full Text:  Brevoord. Helium ventilation for treatment of post-cardiac arrest syndrome: a safety and feasibility study. Resuscitation 2016;epublished July 27th
• Full Text:  Stokes. Are lower levels of red blood cell transfusion more cost-effective than liberal levels after cardiac surgery? Findings from the TITRe2 randomised controlled trial. BMJ Open 2016;6:e011311
• Full Text:  Ramsay. Patient and carer experience of hospital-based rehabilitation from intensive care to hospital discharge: mixed methods process evaluation of the RECOVER randomised clinical trial. BMJ Open 2016;6:e012041

• Crawford. D-dimer test for excluding the diagnosis of pulmonary embolism. Cochrane Database of Systematic Reviews 2016, Issue 8. Art. No.: CD010864
• Zhao. Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non-cardiac surgery. Cochrane Database of Systematic Reviews 2016, Issue 8. Art. No.: CD010726

• Madsen. Immunoglobulin for necrotising soft tissue infections (INSTINCT): protocol for a randomised trial. Dan Med J 2016;63(7):A5250
• Arabi. Thromboprophylaxis using combined intermittent pneumatic compression and pharmacologic prophylaxis versus pharmacologic prophylaxis alone in critically ill patients: study protocol for a randomized controlled trial. Trials 2016;17(1):390

Clinical

Neurological

• Zheng. Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage. Cerebrovasc Dis 2016;42:155-169
• Manning. Endovascular Stroke Management: Key Elements of Success. Cerebrovasc Dis 2016;42:170-177
• Venkat. New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain. CMJ 2016;57:223-8

Circulatory

• Mallone. Cardiovascular Regenerative Technologies: Update and Future Outlook. Transfus Med Hemother 2016;43:291-296
• Anton. Challenges Caring for Adults With Congenital Heart Disease in Pediatric Settings: How Nurses Can Aid in the Transition. Crit Care Nurse August 2016 36:e1-e8
• Sharma. Duration of Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients With and Without Acute Coronary Syndrome. A Systematic Review of Randomized Controlled Trials. Mayo Clin Proc. 2016;91(8):1084-1093
• Chia. Overview of implantable cardioverter defibrillator and cardiac resynchronisation therapy in heart failure management. Singapore Med J 2016; 57(7);354-359

Respiratory

• Beurskens. Use of heliox mechanical ventilation in acute respiratory distress syndrome in adults. Neth J Crit Care 2016;24(4):6-9
• Faßbender. Obstructive Sleep Apnea — a Perioperative Risk Factor. Dtsch Arztebl Int 2016;113(27-28):463-9

Gastrointestinal

• Mössner. The Indications, Applications, and Risks of Proton Pump Inhibitors. A Review After 25 Years. Dtsch Arztebl Int 2016;113(27-28):477-83
• Feuerstein. Diverticulosis and Diverticulitis. Mayo Clin Proc. 2016;91(8):1094–1104

Nutrition

•  Dambaugh. Progressive Care of Obese Patients. Crit Care Nurse 2016;36:58-63

 Renal

• Claure-Del Granado. Fluid overload in the ICU: evaluation and management. BMC Nephrology 2016;17:109
• Lameire. Acute kidney injury in critically ill cancer patients: an update. Critical Care 2016;20:209

Haematological

• Rogers. Thrombotic thrombocytopenic purpura: The role of ADAMTS13. CCJM 2016;83(8):597-603

Sepsis

• Holt. Treating Central Catheter–Associated Bacteremia Due to Methicillin-Resistant Staphylococcus aureus: Beyond Vancomycin. Crit Care Nurse 2016;36:46-57
• Wilson. Role of isavuconazole in the treatment of invasive fungal infections. Therapeutics and Clinical Risk Management 2016;12:1197-1206

Paediatrics

• de Graeff. End-of-life practices: ensuring ‘quality of dying’ during withdrawal of life-sustaining measures. Neth J Crit Care 2016;24(4):10-4

Perioperative

• Misra. Angioedema: Classification, management and emerging therapies for the perioperative physician. Indian J Anaesth 2016;60:534-41

Miscellaneous

• Müller. Hematopoietic Stem Cells in Regenerative Medicine: Astray or on the Path? Transfus Med Hemother 2016;43:247-254
• Cambria. Cardiac Regenerative Medicine: The Potential of a New Generation of Stem Cells. Transfus Med Hemother 2016;43:275-281
• Trimble. The thinking doctor: clinical decision making in contemporary medicine. Clin Med 2016;16:343-346

• Iwashyna. Individualizing endpoints in randomized clinical trials to better inform individual patient care: the TARGET proposal. Critical Care 2016;20:218
• Mehta. Information management for clinicians. CCJM 2016;83(8):589-595
• Niessen. Selection of medical students on the basis of non-academic skills: is it worth the trouble? Clin Med 2016;16:339-342

American Journal of Respiratory & Critical Care Medicine

Commentary

• Redelmeier. Missing the Diagnosis of Brain Death as a Self-Erasing Error. Am J Respir Crit Care Med 2015;192(3):280-282

Chest

Reviews

• Feldman. Community-Acquired Pneumonia: Pathogenesis of Acute Cardiac Events and Potential Adjunctive Therapies. Chest 2015;148(2):523-532
• Davidson. Workplace Blame and Related Concepts: An Analysis of Three Case Studies. Chest 2015;148(2):543-549
• Al-Khafaji. Hepatorenal Disorders. Chest 2015;148(2):550-558

Editorials

• Nathan. Organ Donors: Making the Most of What Is Offered. Chest 2015;148(2):303-305

Case Reports

• Frizzell. A 73-Year-Old Man With Left Lung “White Out”. Chest 2015;148(2):e38-e41
• Thomas. A 37-Year-Old Man With Nonresolving Pneumonia and Endobronchial Lesion. Chest 2015;148(2):e52-e55

Correspondence

• Bordes. Caring for Critically Ill Patients Infected With the Ebola Virus: Logistic and Human Challenges. Chest 2015;148(2):e64-e65
  • Torabi-Parizi. Response. Chest 2015;148(2):e65
• Rho. Another Meaningful End Point for Nighttime Intensivist Coverage. Chest 2015;148(2):e66
• Sriratanaviriyakul. Should Quality of Care Provided by Nighttime Intensivists Be Judged by Mortality? Chest 2015;148(2):e66-e67
  • Kerlin. Response. Chest 2015;148(2):e67-e68
• Pope. Brain Death: Legal Duties to Accommodate Religious Objections. Chest 2015;148(2):e69
• Yanke. The US Uniform Determination of Death Act: Will It Survive a Constitutional Challenge? Chest 2015;148(2):e69-e70
  • Luce. Response. Chest 2015;148(2):e70-e71

Anesthesiology

Reviews

• Dell’Anna. Perioperative Management of a Young Woman with Fontan Repair for Major Gynecologic Surgery. Anesthesiology 2016;124:464-470
• Hayhurst. Differential Opioid Tolerance and Opioid-induced Hyperalgesia: A Clinical Reality. Anesthesiology 2016;124:483-488
• Neudecker. Emerging Roles for MicroRNAs in Perioperative Medicine. Anesthesiology 2016;124:489-506
• Matioc. An Anesthesiologist’s Perspective on the History of Basic Airway Management: The “Preanesthetic” Era—1700 to 1846. Anesthesiology 2016;124:301-311
  • Editorial:  Bause. Airway Command from 1700 to 1846: An Historical Review. Anesthesiology 2016;124:264

Commentaries

• Avidan. Persistent Postoperative Cognitive Decline?: The Pyramid of Evidence. Anesthesiology 2016;124:A23

Anesthesia & Analgesia

Reviews

• Solomon. Can the Viscoelastic Parameter α-Angle Distinguish Fibrinogen from Platelet Deficiency and Guide Fibrinogen Supplementation? Anesth Analg 2015;121(2):289–301
• Lohser. Lung Injury After One-Lung Ventilation: A Review of the Pathophysiologic Mechanisms Affecting the Ventilated and the Collapsed Lung. Anesth Analg 2015;121(2):302–318
• Goucher. Cell Salvage in Obstetrics. Anesth Analg 2015;121(2):465-468
• Grigg. Smarter Clinical Checklists: How to Minimize Checklist Fatigue and Maximize Clinician Performance. Anesth Analg 2015;121(2):570–573
• Morey. Joint Commission and Regulatory Fatigue/Weakness/Overabundance/Distraction: Clinical Context Matters. Anesth Analg 2015;121(2):394–396
• Schonberger. The Surgical Care Improvement Project Antibiotic Guidelines: Should We Expect More Than Good Intentions? Anesth Analg 2015;121(2):397-403

Ultrasound

• Cherry. Multimodal Evaluation of Aortic Regurgitation After Mitral and Tricuspid Valve Repairs. Anesth Analg 2015;121(2):319–322
• Weiner. Transesophageal Echocardiographic Assessment of Left Ventricular Mass. Anesth Analg 2015;121(2):323-328
• Konoske. Intraoperative Evaluation of Paravalvular Regurgitation by Transesophageal Echocardiography. Anesth Analg 2015;121(2):329–336

British Journal of Anaesthesia

Reviews

• Veselis. Memory formation during anaesthesia: plausibility of a neurophysiological basis. Br J Anaesth 2015;115(suppl 1):i13-i19
• Mashour. Intraoperative awareness: controversies and non-controversies. Br J Anaesth 2015;115(suppl 1):i20-i26
• Hagihira. Changes in the electroencephalogram during anaesthesia and their physiological basis. Br J Anaesth 2015;115(suppl 1):i27-i31 
• Pandit. Interpretations of responses using the isolated forearm technique in general anaesthesia: a debate. Br J Anaesth 2015;115(suppl 1):i32-i45
• Mahmoud. Dexmedetomidine: review, update, and future considerations of paediatric perioperative and periprocedural applications and limitations. Br J Anaesth 2015;115(2):171-182 
• Lu. Perioperative acupuncture modulation: more than anaesthesia. Br J Anaesth 2015;115(2):183-193
• Tzimas. Impact of metabolic syndrome in surgical patients: should we bother? Br J Anaesth 2015;115(2):194-202
• Gennai. Cell-Based therapy for traumatic brain injury. Br J Anaesth 2015;115(2):203-212

Editorials

• Avidan. The diving bell and the butterfly Br J Anaesth 2015;115(suppl 1):i8-i10
• Schneider. Restrict relaxants, be aware, and know the limitations of your depth of anaesthesia monitor. Br J Anaesth 2015;115(suppl 1):i11-i12
• McGrath. The NCEPOD study: on the right trach? lessons for the anaesthetist. Br J Anaesth 2015;115(2):155-158
• Bolliger. Haemostatic efficacy of fibrinogen concentrate: is it the threshold or the timing of therapy? Br J Anaesth 2015;115(2):158-161
• Sundaram. Reliable critical care: making it easy to do the right thing. Br J Anaesth 2015;115(2):161-163
• Pilge. BIS and state entropy of the EEG - comparing apples and oranges. Br J Anaesth 2015;115(2):164-166 
• Wong. Anaesthesia for preterm Caesarean delivery: is it different from term deliveries? Br J Anaesth 2015;115(2):166-168
• Noppens. Ventilation through a ‘straw’: the final answer in a totally closed upper airway? Br J Anaesth 2015;115(2):168-170

Anaesthesia

Editorials

• Wiles. ATLS: Archaic Trauma Life Support?. Anaesthesia 2015;70:893–897
• Jenkins. Training and assessment of non-technical skills in the operating theatre: where next?. Anaesthesia 2015;70:897–902

Respiratory Care

Reviews

• Naik. Variability in Mechanical Ventilation: What's All the Noise About? Respir Care 2015;60:8 1203-1210
• Sathe. Pharmacologic Agents That Promote Airway Clearance in Hospitalized Subjects: A Systematic Review. Respir Care 2015;60:81061-1070
• Restrepo. Aerosolized Antibiotics. Respir Care 2015;60(6):762-773
• Willson. Aerosolized Surfactants, Anti-Inflammatory Drugs, and Analgesics. Respir Care 2015;60(6):774-793
• Ari. Aerosol Therapy in Pulmonary Critical Care. Respir Care 2015;60(6):858-879
• Hess. Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula. Respir Care 2015;60(6):880-893
• O'Malley. Device Cleaning and Infection Control in Aerosol Therapy. Respir Care 2015;60(6):917-930
• Hartland. Alveolar Recruitment Maneuvers Under General Anesthesia: A Systematic Review of the Literature. Respir Care 2015;60(4):609-620
• Jeganathan. Ventilator Liberation for High-Risk-for-Failure Patients: Improving Value of the Spontaneous Breathing Trial. Respir Care 2015;60(2):290-296
  
  • Editorial:  Loik. The Spontaneous Breathing Trial: Separating Fact From Fiction. Respir Care 2015;60(2):306

Editorials

• Willis. Mechanical Insufflation-Exsufflation: The Good, the Bad, and the Ugly. Respir Care 2015;60(7):1081-1082

Case Reports

• Sugiyama. Severe Re-expansion Pulmonary Edema Induced by One-Lung Ventilation. Respir Care 2015;60(8):e134-e140
• Dooley. Pneumothoraces Post Mechanical Cardiopulmonary Resuscitation: A Case Series. Respir Care 2015;60(7):e118-e121
• Dugernier. Neurally Adjusted Ventilatory Assist During Weaning From Respiratory Support in a Case of Guillain-Barré Syndrome. Respir Care 2015;60(4):e68-e72
• Kallet. The Complexity of Interpreting Plateau Pressure in ARDS. Respir Care 2015;60(1):147-149

Medicina Intensiva

Reviews

• Cardinal-Fernández. Acute Respiratory Distress: From syndrome to disease. Med Intensiva 2016;40:169-75
• Hidalgo. Infections in critically ill burn patients. Med Intensiva 2016;40:179-85

Case Reports

• Agudo. Atypical hemolytic uremic syndrome in intensive care: Case report in an adult. Med Intensiva 2016;40:189-91

Critical Care & Resuscitation

Editorials

• Anstey. Can we tell what patients die of? Does it matter? Crit Care Resusc 2016;18(1):3-4
• Anstey. Choices, consequences and cost: low-value treatments and intensive care medicine. Crit Care Resusc 2016;18(1):5-7

Correspondence

• Grace. The case for legislation: explicit rather than implicit rationing (who gets into the ICU and who doesn’t. Crit Care Resusc 2016;18(1):62

• Kundra. Are we ready for submental diversions?. Indian J Anaesth 2016;60:531-3
• Singer. Focus on nutrition. Intensive Care Med 2016;epublished August 3rd
• Michalsen. How to implement the withdrawal of life-sustaining measures: a Dutch perspective. Neth J Crit Care 2016;24(4):4-5

• Šućur. Nobel Peace Prize nomination for Doctors Against Forced Organ Harvesting (DAFOH) – a recognition of upholding ethical practices in medicine. CMJ 2016;57:219-22

Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.

Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.

Following last year's massively successful event, the UK Intensive Care Society's State-of-the-Art Meeting is starting its build-up to 2016. The ICS completely changed its game in 2015, and relaunched SOA as a new beacon for forward-looking clinical content, open-access education, and medical social media. In keeping with the times, the podcasts and other materials from last year's meeting have been made open access.
 
This year the programme is looking even better, with topics ranging from the futuristic (space medicine, Formula 1 applied technology, Google Deepmind, and AI) through to the human, practical, and controversial (look out for the clinical scenarios, controversies, and the "From Ivory Tower to Desert Island" session).  Speakers include Peter Brindley, Kevin Fong, Jack Iwashyna, Kath Maitland, Louise Rose, Mervyn Singer, and Jean-Louis Vincent among many others.  It runs from Mon 5th - Wed 7th Dec, and I hope I'll see you there.  Keep an eye on http://soa.ics.ac.uk for programme and registration, and meanwhile enjoy the comprehensive FOAM from last year.

The 1st World Sepsis Congress will take place completely online on September 8th and 9th, 2016, as a prelude and introduction to the fifth World Sepsis Day on September 13th, 2016. Participation is open to everyone with an internet connection and free of charge. In 13 distinctive sessions, over 70 speakers from over 20 countries will give 10-minute keynotes and presentations on the number one preventable cause of death worldwide: sepsis. After each talk, the speakers will answer live questions from the audience.

Highlights include the Opening Session, titled "Sepsis - A Global Health Threat", with German Minister Helge Braun, Marie-Paule Kieny, Assistant Director-General of the WHO, Achim Steiner, former Under-Secretary General UN and Director of UNEP, and Joe Kiani, Founder & CEO of the Patient Safety Movement Foundation. To read the full invitation letter from the program chairs, Simon Finfer and Konrad Reinhart, please click here.

Register   |   Program   |   Sponsors

(Image from Chensiyuan via Wikipedia)

This adult and paediatric ICM meeting is jointly organized by the Society of Intensive Care Medicine (SICM), Singapore and the Australia-New Zealand Intensive Care Society (ANZICS) and is scheduled for 20-24 April 2017 in Suntec Convention Centre, Singapore. It has grown from its humble beginnings in a small hospital venue to become one of the best ICM conference in the Asia-Pacific region. Past editions featured prominent speakers such as Jean Louis Vincent, Daniel De Backer, John J Marini, Rinaldo Bellomo amongst many others, and in this edition the list of distinguished international panel of speakers, program schedule and planned workshops look more impressive than ever. Beside the obvious educational benefits, this conference is also a great opportunity to experience the unique Singaporean culture, enjoy its famed gastronomy and visit its attractions. 

Registration is yet to open so do subscribe to its newsletter at www.sg-anzics.com for updates.