CCR-Newsletter-BannerNewsletter 234  |  June 5th 2016

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CCR Muhammad Ali opt

Muhammed Ali (1942 - 2016)


Welcome to the 234th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a massive newsletter this week, so just get stuck in and see what takes your interest. This week's Topic of the Week is gastrointestinal haemorrhage, starting with a paper on the management of variceal and nonvariceal upper gastrointestinal bleeding in patients with cirrhosis in tomorrow's Paper of the Day.


Many thanks to those of you who completed our effect size survey. If you have 5 minutes, I have one final survey for you to consider helping with. The RADAR study aims to understand the perspectives of intensivists regarding fluid management in ICU patients. Your views will help to inform the design of future trials in which it is planned to test the hypothesis that active deresuscitation (minimisation of fluid administration, together with diuretics and perhaps ultrafiltration) of critically ill patients who have fluid accumulation may lessen the morbidity of critical illness.  This survey is supported by the UK Intensive Care Foundation, European Society of Intensive Care Medicine and the Canadian Critical Care Trials Group. As with all such surveys involving multiple choice questions, there may not be an answer which perfectly fits with your preferred answer - in that case please select the closest match.



Review Articles











American Journal of Respiratory and Critical Care Medicine





Case Reports





Anesthesia & Analgesia


British Jouranl of Anaesthesia


BJA Education

Critical Care & Resuscitation





  • Sharing clinical trial data. Lancet 2016;387(10035):2287 -  Hayes  |  Dugas


SMACC DUB is just one week away! If you haven't yet booked your pre-conference workshop, then the "Stop Gambling - Applying Evidence to Practice" session comes highly recommended (...cough...). You will be encouraged to doubt the ground on which you stand, then come to terms with how we handle that uncertainty in real life practice – without becoming a nihilist.

Stop Gambling

The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday 11th June 2016, and two Clinical Research Foundation Workshops on Sunday 12th & Monday 13th June 2016. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. Inaddition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.

A networking dinner will be hosted on Monday 13th June 2016 in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day.  Please contact Louise at to register for the meeting and meal.

The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. The meeting programme and registration are available on the brand new, and beautiful, Intensive Care Society of Ireland website.



The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.


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(image from Wikimedia)

CCH Journal

After being offline for a few months with a technical problem with our website, Critical Care Horizons is back this week with a new paper to be published. If you have something interesting to say, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.


I hope you find these links useful.

Until next week