CCR-Newsletter-BannerNewsletter 231  |  May 15th 2016

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Welcome to the 231st Critical Care Reviews Newsletter, bringing you the most important research and open access articles from the past seven days. For the third and final week, along with some friends, I'm asking for some help! See the message below from Paul Young.


 Effect Size Survey opt

"You are invited to participate in a survey designed to provide estimates of ‘pre-test probability’ that hypotheses for major ongoing trials in critically ill adults are correct.  These probability estimates will then be used to aid our understanding of what the trial results mean when the trials are completed.  We think that you will find the survey interesting to complete because it will provide some information about major ongoing trials in the field.  We estimate that it will take you around 10 minutes to do.  We want as many Critical Care Reviews subscribers as possible to respond to the survey.In order to record the number of people who could complete the survey, we're asking you to register for the newsletter and complete it via this route."

To celebrate the recruitment of the first patient into the REST Trial, this week's Topic of the Week is carbon dioxide, starting with a paper on extracorporeal CO2 removal: Technical and physiological fundaments in tomorrow's Paper of the Day.



Review Articles









There is only one month to SMACC DUB. If you haven't yet booked your pre-conference workshop, then the "Stop Gambling - Applying Evidence to Practice" session comes highly recommended (...cough...). You will be encouraged to doubt the ground on which you stand, then come to terms with how we handle that uncertainty in real life practice – without becoming a nihilist.

Stop Gambling

The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.

A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day.  Book before 1st May to avail of the Early Bird option of €30 (limited availability).

Please contact Louise at to register for the meeting and meal.

The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. The meeting programme and registration are available on the brand new, and beautiful, Intensive Care Society of Ireland website.


The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  The website has caught a cold, but will be back up very soon.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.


I hope you find these links useful.

Until next week


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