CCR-Newsletter-BannerNewsletter 227  | April 17th 2016

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Welcome to the 227th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

It's a packed newsletter this week, whose highlights are the Brazilian CHECKLIST-ICU randomised controlled trial investigating checklists in the ICU, as well as three guidelines: the latest updated European guideline on management of major bleeding and coagulopathy following trauma, a German guideline on intravascular volume therapy in adults, and an AAGBI guideline on the use of blood components and their alternatives 2016. There are loads of great review articles to choose from, but if you only have time for one, try either this paper on personalizing mechanical ventilation for acute respiratory distress syndrome or this one on Intravenous Fluids in AKI: A Mechanistically Guided Approach.

This week's Topic of the Week is palliation in critical care, starting with a paper on The Changing Role of Palliative Care in the ICU in tomorrow's Paper of the Day.

As anticipation builds to SMACC DUB in just 10 weeks time, here's a taster as to what to expect, with the release of my SMACC Chicago debate with Paul Marik (who is coming to #CCR17) on predicting fluid responsiveness. Huge thanks to Scott Weingart for synching the audio to the animated movie. Also, a small number of print editions of the Critical Care Reviews Book 2016 are still available. They cost little more than the price of postage and packaging. The pdf is available as a free download.


Marik Debate Image cropped opt

 Mac Sweeney vs Marik - Predicting Fluid Responsiveness is a Waste of Time



Review Articles











There are less than three months to SMACC DUB. The presentation podcasts from Chicago are available at Intensive Care Network. See you in Dublin in June!

Dublin opt

(Image from Wikimedia)

The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.

A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day.  Book before 1st May to avail of the Early Bird option of €30 (limited availability).

Please contact Louise at to register for the meeting and meal.

The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. Registration hasn't yet opened, but the meeting programme is available here.


The 13th Annual Critical Care Symposium is on April 28th and 29th in Manchester Town Hall, England. This meeting aims to bring together world renowned speakers for a conference outside London and to provide a conducive environment allowing informal discussion. Most importantly, this event provides good quality education covering various topics in Intensive Care at an affordable price.

The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.


I hope you find these links useful.

Until next week