Welcome to the 222nd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a small newsletter this week, whose highlight is likely to be one of my favourite papers of the year, on The Fragility Index in Multicenter Randomized Controlled Critical Care Trials. There are also great reviews on Guillain-Barré syndrome, mechanical circulatory support for destination therapy and massive transfusion protocols, as well as fantastic editorials on vasopressors in shock and early goal-directed therapy. If you only have time to read one article this week, try this thought-provoking commentary on the management of a difficult ethical case.
Following on from last week's selection of papers on central venous catheterisation, this week's Topic of the Week is complications of central venous catheterisation, starting with a general paper in tomorrow's Paper of the Day.
- Full Text: Schmid. Algorithm-guided goal-directed haemodynamic therapy does not improve renal function after major abdominal surgery compared to good standard clinical care: a prospective randomised trial. Critical Care 2016;20:50
- Full Text: Smit. Moderate hyperoxic versus near-physiological oxygen targets during and after coronary artery bypass surgery: a randomised controlled trial. Critical Care 2016;20:55
- Abstract: Wang. Efficacy and Safety of 1-Hour Infusion of Recombinant Human Atrial Natriuretic Peptide in Patients With Acute Decompensated Heart Failure: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial. Medicine 2016;95(9):e2947
- Full Text: Wang. Lung ventilation strategies for acute respiratory distress syndrome: a systematic review and network meta-analysis. Sci Rep 2016;;6:22855
- Abstract: Wetterslev. Systematic review of cardiac output measurements by echocardiography vs. thermodilution: the techniques are not interchangeable. Intensive Care Med 2016;epublished March 1st
- Abstract: Allingstrup. Antithrombin III for critically ill patients: a systematic review with meta-analysis and trial sequential analysis. Intensive Care Med 2016;42(4):505-520
- Full Text: Jiang. Early goal-directed resuscitation for patients with severe sepsis and septic shock: a meta-analysis and trial sequential analysis. Scand J Trauma Resusc Emerg Med 2016;24(1):23
- Full Text: Yu. Effect of early goal-directed therapy on mortality in patients with severe sepsis or septic shock: a meta-analysis of randomised controlled trials. BMJ Open 2016;6:e008330
- Abstract: Ridgeon. The Fragility Index in Multicenter Randomized Controlled Critical Care Trials. Critical Care Med 2016;epublished March 9th
- Full Text: Whitson. Feasibility, utility, and safety of midodrine during recovery phase from septic shock. Chest 2016;epublished March 10th
- Abstract: Rush. Trends in Extracorporeal Membrane Oxygenation for the Treatment of Acute Respiratory Distress Syndrome in the United States. J Intensive Care Med 2016;epublished February 17th
- Abstract: Karagiannidis. Extracorporeal membrane oxygenation: evolving epidemiology and mortality. Intensive Care Med 2016;epublished March 4th
- Abstract: McCauley. Use of Tracheal Aspirate Culture in Newly Intubated Patients with Community-Onset Pneumonia. Annals of the American Thoracic Society 2016;13(3):376-381
- Abstract: Kentish-Barnes. CAESAR: a new tool to assess relatives’ experience of dying and death in the ICU. Intensive Care Med 2016;epublished March 7th
- Full Text: Hayakawa. High d-dimer levels predict a poor outcome in patients with severe trauma, even with high fibrinogen levels on arrival: a multicenter retrospective study. shock 2016;45(3):308–314
- Full Text: Paiva. Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study. Critical Care 2016;20:53
- Full Text: Sundström. Measuring energy expenditure in the intensive care unit: a comparison of indirect calorimetry by E-sCOVX and Quark RMR with Deltatrac II in mechanically ventilated critically ill patients. Critical Care 2016;20:54
- Rodrigo. Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD010406
- Bruschettini. Frequency of endotracheal suctioning for the prevention of respiratory morbidity in ventilated newborns. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD011493
- Robertson. Vascular closure devices for femoral arterial puncture site haemostasis. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD009541
- Willison. Guillain-Barré syndrome. Lancet 2016;epublished February 29th
- Ferri. Endovascular thrombectomy for the treatment of acute ischemic stroke. Arq Neuropsiquiatr 2016;74(1):67-74
- Tozzi. Mechanical circulatory support for destination therapy. Swiss Med Wkly. 2016;146:w14267
- Naegele. Medical therapy of heart failure with reduced ejection fraction: current evidence and new developments. Swiss Med Wkly 2016;146:w14295
- Biedrzycka. Tissue oximetry in anaesthesia and intensive care. Anaesthesiol Intensive Ther 2016;48(1):41-48
- Maraví-Poma. Current Status in the Management of Acute Pancreatitis. Emergency Med 2015;6:297
- Williams. Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms. World J Nephrol 2016;5(2):152-157
- Valerio. Human albumin solution for patients with cirrhosis and acute on chronic liver failure: Beyond simple volume expansion. World J Hepatol 2016;8(7):345-354
- Gasperi. Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery? World J Hepatol 2016;8(7):345-354
- Bunchorntavakul. Bacterial infections in cirrhosis: A critical review and practical guidance. World J Hepatol 2016;8(6):307-321
- Farooqi. Major comorbid disease processes associated with increased incidence of acute kidney injury. World J Nephrol 2016;5(2):139-146
- Hsu. Use of percutaneous nephrostomy and ureteral stenting in management of ureteral obstruction. World J Nephrol 2016;5(2):172-181
- Hsu. Massive transfusion protocols: current best practice. International Journal of Clinical Transfusion Medicine 2016;4:15-27
- Ieko. Profiles of direct oral anticoagulants and clinical usage—dosage and dose regimen differences. Journal of Intensive Care 2016;4:19
- Fontana. Direct oral anticoagulants: a guide for daily practice. Swiss Med Wkly. 2016;146:w14286
- Kellum. Acute Dialysis Quality Initiative (ADQI) XIV sepsis phenotypes and targets for blood purification in sepsis: The Bogotá Consensus. Shock 2016;45:242–248
- Guido. In vitro diagnosis of sepsis: a review. Pathology and Laboratory Medicine International 2016;8:1-14
- McGill. The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults. Journal of Infection 2016;72:405-438 (ht Manu Malbrain)
- People’s Liberation Army Professional Committee of Critical Care Medicine. Expert consensus on standardized diagnosis and treatment for heat stroke. Mil Med Res 2016;3:1
- Dünser. Vasopressors in shock: are we meeting our target and do we really understand what we are aiming at? Intensive Care Med 2016;epublished March 1st
- Brower. What’s new in ARDS: can we prevent it? Intensive Care Med 2016;epublished March 1st
- De Backer. Early goal-directed therapy: do we have a definitive answer? Intensive Care Med 2016;epublished March 7th
- Bernard. The definition of ARDS revisited: 20 years later. Intensive Care Med 2016;epublished March 4th
- Danz. Hyponatremia among Triathletes in the Ironman European Championship. N Engl J Med 2016;374:997-998
- Skoczyński. Cut-off point for switching from non- -invasive ventilation to intubation in severe ARDS. Still a spectrum of greys and whites. Anaesthesiol Intensive Ther 2016;48(1):61-62
- Quintin. Cut-off point for switching from non- -invasive ventilation to intubation in severe ARDS. Fifty shades of grey? Anaesthesiol Intensive Ther 2016;48(1):62-64
- Taylor. Ketamine—the real perspective. Lancet 2016;epublished March 11th
- Pereira. When one port does not return blood: two case reports of rare causes for misplaced central venous catheters. Rev Bras Anestesiol 2016;66(1)
- Dinh. Critical illness myopathy and whole body MRI. Intensive Care Med 2016;42(4):587-587
- Starzyk. Snaring swans: intraoperative knotting of pulmonary artery catheters. Anaesthesiol Intensive Ther 2016;48(1):66-70
- Dahine. Ultrasound findings in critical care patients: the “liver sign” and other abnormal abdominal air patterns. Critical Ultrasound Journal 2016;8:2
The 13th Annual Critical Care Symposium is on April 28th and 29th in Manchester Town Hall, England. This meeting aims to bring together world renowned speakers for a conference outside London and to provide a conducive environment allowing informal discussion. Most importantly, this event provides good quality education covering various topics in Intensive Care at an affordable price.
The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.
The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. Registration hasn't yet opened, but the meeting programme is available here.
The Irish Association of Critical Care Nurses (IACCN) are holding their Annual Conference in Limerick on April 7th. Further details and the meeting programme are available here.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week