Welcome to the 210th Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals. It's a short newsletter, as most publishers wind down for the festive season. The highlights of this edition are randomized controlled trials investigating the effect of paracetamol on core temperature in traumatic brain injury and the open lung approach in ARDS, as well as review articles on ECMO and recruitment maneuvers in ARDS.
This week's Topic of the Week is Eye Emergencies, starting with a paper on ophthalmological Issues in the intensive care unit in tomorrow's Paper of the Day.
It's just 6 weeks to the Critical Care Reviews Meeting 2016, on Friday January 29th at the Titanic Centre, Belfast. The promotional video for the event, "It's Coming", is included above. #CCR16 promises to be another fantastic meeting, so don't miss out. If you are travelling for this, please book your hotel room soon, as unused reserved rooms will be released back for general sale in the near future. There may still be vacancies, but not at the reduced meeting rate.
- Full Text: Saxena. The Effect of Paracetamol on Core Body Temperature in Acute Traumatic Brain Injury: A Randomised, Controlled Clinical Trial. PLoS One 2015;10(12):e0144740
- Abstract: Kacmarek. Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial. Critical Care Med 2016;44(1):32-42
- Abstract: Axelrod. A Double-Blinded, Randomized, Placebo-Controlled Clinical Trial of Aminophylline to Prevent Acute Kidney Injury in Children Following Congenital Heart Surgery With Cardiopulmonary Bypass. Pediatr Crit Care Med 2015;epublished December 11th
- Abstract: Walsh. Effects of remote ischemic preconditioning in high-risk patients undergoing cardiac surgery (Remote IMPACT): a randomized controlled trial (Remote IMPACT Study). CMAJ 2015;epublished December 14th
- Abstract: Tolboom. Moderate hypothermia during ex vivo machine perfusion promotes recovery of hearts donated after cardiocirculatory death. Eur J Cardiothorac Surg 2015;49:25-31
- Abstract: Hypes. Video Laryngoscopy Improves Odds of First Attempt Success at Intubation in the ICU: A Propensity-Matched Analysis. Ann Am Thorac Soc 2015;epublished December 14th
- Abstract: Kangelaris. Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Critical Care Med 2016;44(1):120–129
- Abstract: Beitler. Volume Delivered During Recruitment Maneuver Predicts Lung Stress in Acute Respiratory Distress Syndrome. Critical Care Med 2016;44(1):91–99
- Full Text: Schley. Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury. PLoS One 2015;15;10(12):e0145042
- Almeida. Antibiotic prophylaxis for surgical site infection in people undergoing liver transplantation. Cochrane Database of Systematic Reviews 2015, Issue 12. Art. No.: CD010164
- Simancas-Racines. Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion. Cochrane Database of Systematic Reviews 2015, Issue 12. Art. No.: CD009745
- Mosier. Extracorporeal membrane oxygenation (ECMO) for critically ill adults in the emergency department: history, current applications, and future directions. Critical Care 2015;19:431
- van der Lende. Cardiac arrhythmias during or after epileptic seizures. J Neurol Neurosurg Psychiatry 2016;87:69-74
- Parissis. Current randomized control trials, observational studies and meta analysis in off-pump coronary surgery. Journal of Cardiothoracic Surgery 2015;10:185
- Byrne. Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Grüntzig Lecture ESC 2014. Eur Heart J 2015;36:3320-3331
- Géloën. Pressor Response to Noradrenaline in the Setting of Septic Shock: Anything New under the Sun—Dexmedetomidine, Clonidine? A Minireview. BioMed Research International 2015;2015:863715
- Santos. Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way. World J Crit Care Med 2015;4(4):278-286
- Votruba. The Role of Airway and Endobronchial Ultrasound in Perioperative Medicine. BioMed Research International 2015;2015:754626
- Shum. Recent knowledge on the pathophysiology of septic acute kidney injury: A narrative review. J Crit Care 2016;31(1):82–89
- Le Neindre. Thoracic ultrasound: Potential new tool for physiotherapists in respiratory management. A narrative review. J Crit Care 2016;31(1):101-109
- Grover. The why and wherefore of hepatic encephalopathy. International Journal of General Medicine 2015;8:381-390
- Liu. Advances in cirrhosis: Optimizing the management of hepatic encephalopathy. World J Hepatol 2015;7(29):2871-2879
- Memeo. Management of biliary complications after liver transplantation. World J Hepatol 2015;7(29):2890-2895
- Faisal. Recurrence of autoimmune liver diseases after liver transplantation. World J Hepatol 2015;7(29):2896-2905
- Primignani. Therapeutic and clinical aspects of portal vein thrombosis in patients with cirrhosis. World J Hepatol 2015;7(29):2906-2912
- Villa. Extracorporeal Membrane Oxygenation and the Kidney. Cardiorenal Med 2016;6:50-60
- Wybraniec. Renalase and Biomarkers of Contrast-Induced Acute Kidney Injury. Cardiorenal Med 2016;6:25-36
- Kokubo. Evaluation of the Biocompatibility of Dialysis Membranes. Blood Purif 2015;40:293-297
- Martínez. Ebola Virus Infection: Overview and Update on Prevention and Treatment. Infectious Diseases and Therapy 2015;4(4):365-390
- Bergen. Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria. Infectious Diseases and Therapy 2015;4(4):391-415
- Wells. Improvements in the management of neutropenic sepsis: lessons learned from a district general hospital. Clin Med 2015;15(6):526-530
- Oostdijk. Selective decontamination in ICU patients: Dutch guideline. Neth J Crit Care 2015;23(5):5-9
- Cotogni. Deep sternal wound infection after cardiac surgery: Evidences and controversies. World J Crit Care Med 2015;4(4):265-273
- Papathanasiou. Why there is a need to discuss pulmonary hypertension other than pulmonary arterial hypertension? World J Crit Care Med 2015;4(4):274-277
- Shelley. A value forgotten in doctoring: Empathy. Arch Med Health Sci 2015;3:169-73
- Meckel. Proper Patient Selection - The Key to Beneficial Mechanical Thrombectomy in Acute Stroke Therapy. Cerebrovasc Dis 2015;40:304-306
- Marrone. New Era for Stroke Therapy: Is This a Global Perspective? Cerebrovasc Dis 2015;40:307
- Horn. Hot topics in intensive Care 2015. Neth J Crit Care November 2015;23(5):26-8
- Walter. Manganese toxicity in critical care: Case report, literature review and recommendations for practice. JICS 2015;epublished December 10th
- de Gier. Respiratory insufficiency due to acute bulbar palsy. Neth J Crit Care 2015;23(5):18-20
- Beernink. Pneumoperitoneum after a bilateral pneumothorax. Neth J Crit Care 2015;23(5):21-2
Due to hugely successful previous events, the Critical Care Reviews Meeting 2016 has been moved to a brand new venue, the stunning, multi-million pound Titanic Centre, birthplace of RMS Titanic, As before, the meeting theme is to review the biggest studies of the previous year, with chief investigators present where possible to discuss their work in person. From Wellington, New Zealand, Dr Paul Young will talk on his studies SPLIT (saline versus plasmalyte) and HEAT (paracetamol for pyrexia control). Dr John Holcomb (Houston, USA) will review his mega trial PROPPR, evaluating blood product transfusion ratios in traumatic haemorrhage. Dr Anthony Gordon (London, England), will review his VANISH study, a multi-centre randomized controlled trial comparing vasopressin with noradrenaline, with or without hydrocortisone, for first-line vasopressor support in septic shock. Prof Tim Walsh (Edinburgh, Scotland) will review the ABLE study, including his ABLE UK component, evaluating age of transfused red cells, as well as RECOVER, a post-ICU rehab study. In addition, two of the most eminent intensivists in global critical care, Prof Jean-Louis Vincent (Brussels, Belgium) and Prof Luciano Gattinoni (Milan, Italy) will be on hand to discuss the significance of these findings. A new feature for the meeting is the John Hinds' Trauma Lecture, with Dr Brian Burns (Sydney HEMS, Australia) travelling across the world to deliver the inaugural presentation. It won't be all study discussion, with other elements to the meeting, including the spectacularly popular "Informal Chat", taking place that evening.
If you haven't yet attended this modern, niche meeting, then put the date Friday January 29th in your diary. Both delegate and speaker feedback from previous meetings has been incredibly positive, allowing the event to grow and attract some of the biggest names in critical care. The Titanic Centre is just minutes from Belfast City Airport, with a hotel within 3 minutes walking distance, and is a 20 minute walk from the city centre, including the Cathedral Quarter, Belfast's cultural centre full of great restaurants and pubs. Further details regarding delegate rate accommodation should be available in the next week or two. Talks are given in the setting of the rebuilt famous staircase from the great ship, while both the "Informal Chat" session and dinner overlook the floodlit slipways where Titanic and Olympic were launched. Ton finish a fantastic day, we have a pre-dinner talk from a colleague of mine, Mr Chris Andrews, on "My Great Great Uncle Thomas Andrews - The Man Who Built Titanic".
With some exciting new innovations planned, this new meeting promises to delivery on its burgeoning reputation. Don't wait too long before registering, as numbers are capped to keep this an intimate event. It is as strong a one day programme as you could possibly find. If you think your colleagues would find this event interesting, please circulate this information - this is a not-for-profit event, run in association with the Northern Ireland Intensive Care Society.
The next SMACC Conference is on June 13th to 16th, in Dublin, Ireland. Registration opened on October 28th, sold out in a few hours, and closed again. It opened again on December 2nd and sold out in just 15 minutes. Luckily, there is on further batch of tickets available on Wednesday February 3rd. With world leading academics and high profile clincians from the FOAMed critical care world, this conference fuses knowledge, dynamism and enthusiasm with an altruisitic desire to be the best we can be for the benefit of our patients. It's the most fun, modern critical care conference in the world. If you've been lucky enough to register for #smaccDUB, the presentations from SMACC Chicago, which are now online at Intensive Care Network, will give you an idea as to what to expect.
(Image from Wikimedia)
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Have a great Christmas