CCR-Newsletter-BannerNewsletter 202 |  October 25th 2015


Welcome to the 202nd Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals.

The highlights of this week's newsletter are randomized controlled trials on combined ECCO2R and RRT for ARDS with AKI and fever control in traumatic brain injury; observational studies on fluid balance in acute kidney injury and the prognostic significance of bradycardia in survivors of out-of-hospital cardiac arrest; guidelines on PCI for STEMI, infective endocarditis and post-cardiac arrest care; commentaries on the care of migrants; a very public rebuke from the editor-in-chief of the BMJ to the British Secretary of State for Health for the continued deliberate misuse of observational data for political gain, plus review articles on decompressive craniectomy, hypervolaemia and fluid resuscitation in burns.

If you only have time for one paper this week, try this one from my colleagues in the Royal Victoria Hospital in Belfast, proposing a potential role for aspirin in the management of ARDS and providing the rationale for the phase II randomized controlled STAR study.

This week's Topic of the Week is Pelvic Trauma, starting with a paper on angioembolization in tomorrow's Paper of the Day.



If you haven't yet heard, registration for SMACC Dublin opens in just two days time. The exact countdown is available on the SMACC website, but as a guide, registration opens at 21:00 Irish time on Tuesday night.


SMACC Registration opt



Review Articles











Due to hugely successful previous events, the Critical Care Reviews Meeting 2016 has been moved to a brand new venue, the stunning, multi-million pound Titanic Centre, birthplace of RMS Titanic,  As before, the meeting theme is to review the biggest studies of the previous year, with chief investigators present where possible to discuss their work in person. From Wellington, New Zealand, Dr Paul Young will talk on his studies SPLIT (saline versus plasmalyte) and HEAT (paracetamol for pyrexia control). Dr John Holcomb (Houston, USA) will review his mega trial PROPPR, evaluating blood product transfusion ratios in traumatic haemorrhage. Dr Anthony Gordon (London, England), will review his VANISH study, a multi-centre randomized controlled trial comparing vasopressin with noradrenaline, with or without hydrocortisone, for first-line vasopressor support in septic shock. Prof Tim Walsh (Edinburgh, Scotland) will review the ABLE study, including his ABLE UK component, evaluating age of transfused red cells, as well as RECOVER, a post-ICU rehab study. In addition, two of the most eminent intensivists in global critical care, Prof Jean-Louis Vincent (Brussels, Belgium) and Prof Luciano Gattinoni (Milan, Italy) will be on hand to discuss the significance of these findings. A new feature for the meeting is the John Hinds' Trauma Lecture, with Dr Brian Burns (Sydney HEMS, Australia) travelling across the world to deliver the inaugural presentation. It won't be all study discussion, with other elements to the meeting, including the spectacularly popular "Informal Chat", taking place that evening.

If you haven't yet attended this modern, niche meeting, then put the date Friday January 29th in your diary. Both delegate and speaker feedback from previous meetings has been incredibly positive, allowing the event to grow and attract some of the biggest names in critical care. The Titanic Centre is just minutes from Belfast City Airport, with a hotel within 3 minutes walking distance, and is a 20 minute walk from the city centre, including the Cathedral Quarter, Belfast's cultural centre full of great restaurants and pubs. Further details regarding delegate rate accommodation should be available in the next week or two. Talks are given in the setting of the rebuilt famous staircase from the great ship, while both the "Informal Chat" session and dinner overlook the floodlit slipways where Titanic and Olympic were launched. With some exciting new innovations planned, this new meeting promises to delivery on its burgeoning reputation. The finalised programme won't be released until later this Autumn, but don't wait too long before registering, as numbers are capped to keep this an intimate event. It is as strong a one day programme as you could possibly find. If you think your colleagues would find this event interesting, please circulate this information - this is a not-for-profit event, run in association with the Northern Ireland Intensive Care Society.




The next SMACC Conference is on June 13th to 16th, in Dublin, Ireland. Registration opens at 21:00 October 27th Irish time and early registration is highly advised, as the event could book out within 24 hours. With its informal manner and flat hierarchy, this event delivers on its promise to provide top class critical care education in a fun, modern way. Speakers are deliberately chosen for their ability to present and convey information, rather than their academic or social media status, marking this as the field leader in medical conferencing. On a related note, the first presentations from SMACC Chicago are now online also at Intensive Care Network.

This year's State-of-the-Art Meeting promises an exciting programme in a new dynamic format.  It aims to be the first major national society to fully embrace social media and free open access medical education, with an opening plenary session and a workshop, as well full integration of Twitter questions into sessions, live blogging, and open-access AV materials. 

State-of-the-Art is the biggest critical care meeting in the UK, and it's on the move: by combining the resources and influence of the ICS, with a radical redesign and the input of a whole new committee, including several from the FOAMed world, such as Steve Mathieu (The Bottom Line), Jonathan Downham (Critical Care Practitioner), and me. The result should be something unique. It's also the only meeting of this size where the delegates get to steer how the meeting evolves, so have your say.

Take a look at the website or the flyer. The meeting is at London ExCeL, 20 minutes from the West End.



CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.


I hope you find these links useful.

Until next week