Newsletter 120 / March 22nd 2014
Welcome
Hello Rob
Welcome to the 120th Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries and editorials from hundreds of clinical and scientific journals. It's another abbreviated, and slightly early, newsletter, due to conference committments at SMACCgold and travel.
This week's research studies include randomized controlled trials on decompressive hemicraniectomy for stroke, APC for ARDS, sodium nitroprusside in acute myocardial infarction and a summary of results from the Heparin Citrate study. There are a multitude of observational studies which focus on delirium, NT-proBNP, venous thrombosis, healthcare-associated pneumonia and a nutritional substudy from the RENAL trial, while additional studies investigate echcinocandins, hepatorenal syndrome, parenteral nutrition, septic shock and post-stroke blood pressure.
There is one guideline this week, focusing on pelvic trauma, one editorial on medical training and autonomy, and one commentary on antimicrobial resistance. There are two case reports, including a potential game changer for communication with the intubated patient. Amongst the clinical review articles are papers on post-traumatic stress disorder, cardiac resuscitation and coagulation, tracheostomy progression, cirrhosis, critical illness anaemia, sepsis biomarkers, ultrasound and hypertensive disorders of pregnancy.
The topic for This Week's Papers is embolization for haemorrhage, starting with a paper on GI embolization in tomorrow's Paper of the Day.
SMACCgold
The second Social Media and Critical Care conference took place this week on the Gold Coast in Australia. It was an eclectic mix of critical care clinicians and practioners from around the globe, with world class researchers, leading bloggers and high functioning medics all combining to produce a cutting edge conference of science, practicalities and fun. Lots of fun. It's a conference like no other, and next year will be in Chicago May 20 to 22nd. This is a not-for-profit endevour superbly organised by a group of enthusiasts committed to providing free open access medical education. All talks will be made freely available over the next few months on the affiliated websites. The twitter impression left by SMACCgold has already exceeded 25 million, completely dwarfing the traditional (and excellent) Brussels meeting, which, incidently, had as it's top tweeter, the SMACCteam! Social media is changing the landscape of medicine irrevocably and this meeting is going to grow and grow. Hopefully I'll see you next year in the USA. Congratulations to the SMACCgold organising committee for putting together an amazing event and many thanks for the opportunity to be involved.
Research
Randomized Controlled Trials
- Abstract: Jüttler. Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke (Destiny II). N Engl J Med 2014;370:1091-1100
- Full Text: Cornet. Recombinant human activated protein C in the treatment of acute respiratory distress syndrome: a randomized clinical trial. PLoS One 2014;14;9(3):e90983
- Full Text: Siddiqi. Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI). Eur Heart J 2014;epublished March 17th
- Summary: Gattas. The Heparin Citrate study – summary of main results(from icuwhatdidthere.com)
Observational Studies
- Abstract: Patel. Rapidly Reversible, Sedation-related Delirium versus Persistent Delirium in the Intensive Care Unit. Am J Respir Crit Care Med 2014;189(6):658-665
- Abstract: Rhee. Usefulness of N-terminal pro-B-type natriuretic peptide in patients admitted to the intensive care unit: a multicenter prospective observational study. BMC Anesthesiology 2014;14:16
- Abstract: Lamontagne. Nonleg Venous Thrombosis in Critically Ill Adults: A Nested Prospective Cohort Study. JAMA Intern Med 2014; epublsied March 17th
- Abstract: Vallés. Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study. Intensive Care Med 2014;epublished March 18th
- Full Text: Bellomo. Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial Crit Care 2014;18(2):R45
Other Studies of Interest
Observational
- Abstract: Rodríguez. Initial use of echinocandins does not negatively influence outcome in Candida parapsilosis bloodstream infection: a propensity score analysis. Clin Infect Dis 2014;epublished March 18th
- Abstract: Weston. The Efficacy of Daptomycin vs. Vancomycin for MRSA Bloodstream Infection in Patients with Impaired Renal Function Clin Infect Dis 2014;epublished March 18th
- Abstract: Cervera. Effect of Vancomycin Minimal Inhibitory Concentration on the Outcome of Methicillin-Susceptible Staphylococcus aureus Endocarditis Clin Infect Dis 2014;epublished March 18th
- Abstract: Mandorfer. Non-selective ß Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis. Gastroenterology 2014;epublished March 12th
- Abstract: Gershengorn. Temporal Trends in the Use of Parenteral Nutrition in Critically Ill Patients. Chest 2014;145(3):508-517
- Abstract: Lilly. A Multicenter Study of ICU Telemedicine Reengineering of Adult Critical Care. Chest 2014;145(3):500-507
- Abstract: Leligdowicz. Association between source of infection and hospital mortality in patients who have septic shock. Am J Respir Crit Care Med 2014;epublished March 17th
- Abstract: Schummer. Pre-procedure ultrasound increases the success and safety of central venous catheterization. Br J Anaesth 2014;epublished March 18th
- Abstract: Zivanovic. Late Outcomes of a Randomized Trial of High-Frequency Oscillation in Neonates. N Engl J Med 2014; 370:1121-1130
- Full Text: Fischer. Acute post-stroke blood pressure relative to premorbid levels in intracerebral haemorrhage versus major ischaemic stroke: a population-based study. Lancet Neurology 2014;13(4):374-384
- Full Text: Manning. Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial. Lancet Neurology 2014;13(4):364-373 (free registration required)
Guideline
Case Reports
- Girbes. Speech in an Orally Intubated Patient. N Engl J Med 2014; 370:1172-1173
- Perricone. Reexpansion Pulmonary Edema after Thoracentesis. N Engl J Med 2014;370:e19
Clinical Review Articles
Neurological
Circulatory
- Weidman. Cardiac Resuscitation and Coagulation. Anesthesiology 2014;120(4):1009–1014
- Anson. Vascular Access in Resuscitation: Is There a Role for the Intraosseous Route? Anesthesiology 2014;120(4):1015–1031
- Bousselmi. Myocardial ischemic conditioning: Physiological aspects and clinical applications in cardiac surgery. Journal of the Saudi Heart Association 2014;26(2):93-100
Respiratory
Hepatobiliary
- Rognant. Evaluation of renal function in patients with cirrhosis: Where are we now? World J Gastroenterol 2014;2010):2533–2541
- Bolognesi. Splanchnic vasodilation and hyperdynamic circulatory syndrome in cirrhosis. World J Gastroenterol 2014;20(10):2555–2563
- Bruns. Risk factors and outcome of bacterial infections in cirrhosis. World J Gastroenterol 2014;20(10):2542–2554
- Sipeki. Immune dysfunction in cirrhosis. World J Gastroenterol 2014;20(10):2564–2577
- Nardone. Spinal cord involvement in patients with cirrhosis. World J Gastroenterol 2014;20(10):2578–2585
- Tumgor. Cirrhosis and hepatopulmonary syndrome. World J Gastroenterol 2014;20(10):2586–2594
- Hayashi. Management of thrombocytopenia due to liver cirrhosis: A review. World J Gastroenterol 2014;20(10):2595–2605
- Singal. Alcoholic Hepatitis: Current Challenges and Future Directions. Clinical Gastroenterology and Hepatology 2014;12(4):555-564
Haematological
- Koscielny. Rivaroxaban and Hemostasis in Emergency Care. Emergency Medicine International 2014;(2014):935474
- Astin. Anaemia secondary to critical illness: an unexplained phenomenon. Extreme Physiology & Medicine 2014;3:4
- Kearon. Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism. Blood 2014;123(12):1794-1801
- Palareti. How I treat isolated distal deep vein thrombosis (IDDVT). Blood 2014;123(12):1802-1809
Sepsis
Miscellaneous
I hope you find these links useful. Normal service will resume next week.
Until then.
Rob