Critical Care Reviews Meeting 2017
Titanic Centre, Belfast, Northern Ireland
Friday January 27th
Welcome to the 246th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a huge newsletter this week, whose highlights are the the RINSE Trial (published in abstract form only so far), a series of recommendations from the ADQI group on continuous renal replacement therapy, as well as two special issues from the British Journal of Anaesthesia on airway management and vascular anaesthesia. If you only have time for one review article, try this one on advances in the understanding of trauma-induced coagulopathy.
This week's Topic of the Week is based on the BJA's airway management issue, and starts with a paper on strategies to improve first attempt success at intubation in critically ill patients in tomorrow's Paper of the Day.
The Critical Care Reviews Meeting focuses on reviewing and discussing the biggest studies of the year. However, with some of the best thinkers in global critical care on the faculty, we also look at other critical care topics. The 2017 Meeting includes two fascinating such talks - Paul Marik thinks he has discovered a simple intervention which is "The Cure for Sepsis", while John Myburgh will provide his thoughts on how best to design a research trial in "The Path to Truth". Registration is open so don't delay and miss out.
- Abstract: Bernard. Induction of Therapeutic Hypothermia During Out-of-Hospital Cardiac Arrest Using a Rapid Infusion of Cold Saline (The RINSE Trial). Circulation 2016;epublished August 25th
- Abstract: Anstey. A Comparison between Two Dilute Citrate Solutions (15 vs. 18 mmol/l) in Continuous Renal Replacement Therapy: The Base Excess and Renal Substitution Solution Study. Blood Purif 2016;42:194-201
- Abstract: Bracard. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial (THRACE Trial). Lancet Neurology 2016;epublished August 22nd
- Abstract: Donaldson. Why is there still a debate regarding the safety and efficacy of intravenous thrombolysis in the management of presumed acute ischaemic stroke? A systematic review and meta-analysis. Emerg Med Australas 2016;epublished August 25th
- Abstract: Villablanca. Therapeutic hypothermia in ST elevation myocardial infarction: a systematic review and meta-analysis of randomised control trials. Heart 2016;102:712-719
- Full Text: Liu. Noninvasive ventilation with helmet versus control strategy in patients with acute respiratory failure: a systematic review and meta-analysis of controlled studies. Crit Care 2016;20:265
- Full Text: Summers. Incidence and recognition of acute respiratory distress syndrome in a UK intensive care unit. Thorax 2016;epublished August 22nd
- Full Text: Hayakawa. Antithrombin Supplementation and Mortality in Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study. Shock 2016;epublished August 19th
- Full Text: Chiumello. Airway driving pressure and lung stress in ARDS patients. Crit Care 2016;20:276
- Abstract: Ehrlich. Is There an Influence of Routine Daily Transcranial Doppler Examination on Clinical Outcome in Patients After Aneurysmal Subarachnoid Hemorrhage? World Neurosurg. 2016 Apr;88:214-21
- Full Text: Masewu. Acute kidney injury is a powerful independent predictor of mortality in critically ill patients: a multicenter prospective cohort study from Kinshasa, the Democratic Republic of Congo. BMC Nephrol 2016;17(1):118
- Denehy. Ten reasons why ICU patients should be mobilized early. Intensive Care Med 2016;epublished August 25th
- Legriel. What’s new in refractory status epilepticus? Intensive Care Med 2016;epublished August 20th
- Bragge. A State-of-the-Science Overview of Randomized Controlled Trials Evaluating Acute Management of Moderate-to-Severe Traumatic Brain Injury J Neurotrauma 2016;33(16):1461-1478 (OA until Spt 9th only)
- Vadivelu. Role of ketamine for analgesia in adults and children. J Anaesthesiol Clin Pharmacol 2016;32:298-306
- Baarslag. Pharmacological sedation management in the paediatric intensive care unit. J Pharm Pharmacol 2016;epublished August 21st
- Guglin. Left Ventricular Assist Device as Destination Therapy. The VAD Journal 2016;1:2
- Guglin. What Did We Learn About VADs in 2014? The VAD Journal 2016;1:9
- Guglin. Inotropes Are Not Linked to Increased Mortality in Heart Failure. The VAD Journal 2016;1:12
- Alraies. Inotropes Are Linked to Increased Mortality in Heart Failure. The VAD Journal 2016;1:11
- Omar. Renal Replacement Therapy in Patients with Left Ventricular Assist Device: What do the Cardiologists Need to Know? The VAD Journal 2016;1:23
- Mittal. Intraoperative lung ultrasound: A clinicodynamic perspective. J Anaesthesiol Clin Pharmacol 2016;32:288-97
- Husain-Syed. A Protective Kidney-Lung Approach to Improve Outcomes in Mechanically Ventilated Patients. Blood Purif 2016;42:214-218
- Ribeiro. Spontaneous Bacterial Peritonitis: Is It Still A Life-Threatening Issue in Cirrhosis? Journal of Gastroenterology and Hepatology Research 2016;5(4):2102-2111
- Parvez. Bacterial Infection of Liver: A Bird’s Eye View. Journal of Gastroenterology and Hepatology Research 2016;5(4):2112-2114
- Young. What’s new on balanced crystalloid solutions? Intensive Care Med 2016;epublished August 17th
- Toyohara. Novel regenerative therapy for acute kidney injury. Renal Replacement Therapy 2016;2:34
- Ponce. Acute kidney injury: risk factors and management challenges in developing countries. International Journal of Nephrology and Renovascular Disease 2016;9:193-200
- Aneman. Cardiac dysfunction in sepsis. Intensive Care Med 2016;epublished August 20th
- Prucha. Immunotherapy of Sepsis: Blind Alley or Call for Personalized Assessment? Immunol Ther Exp 2016;epublished August 24th
- Asai. Special issue on airway management. Br J Anaesth 2016;117:i1-i3
- Jagannathan. Paediatric difficult airway management: what every anaesthetist should know! Br J Anaesth 2016;117:i3-i5
- Higgs. Airway management in the critically ill: the same, but different. Br J Anaesth 2016;117:i5-i9
- Kelly. Seeing is believing: getting the best out of videolaryngoscopy. Br J Anaesth 2016;117:i9-i13
- Baker. Is it time for airway management education to be mandatory? Br J Anaesth 2016;117:i13-i16
- Baker. The great airway debate: is the scalpel mightier than the cannula? Br J Anaesth 2016;117:i17-i19
- Chrimes. The Vortex: a universal ‘high-acuity implementation tool' for emergency airway management. Br J Anaesth 2016;117:i20-i27
- Duggan. Transtracheal jet ventilation in the ‘can't intubate can't oxygenate’ emergency: a systematic review. Br J Anaesth 2016;117:i28-i38
- Kristensen. Ultrasonographic identification of the cricothyroid membrane: best evidence, techniques, and clinical impact. Br J Anaesth 2016;117:i39-i48
- Mercer. Systematic review of the anaesthetic management of non-iatrogenic acute adult airway trauma. Br J Anaesth 2016;117:i49-i59
- Natt. Strategies to improve first attempt success at intubation in critically ill patients. Br J Anaesth 2016;117:i60-i68
- Cheng. Novel endovascular procedures and new developments in aortic surgery. Br J Anaesth 2016;117:ii3-ii12
- So. Intraoperative neuromonitoring in major vascular surgery. Br J Anaesth 2016;117:ii13-ii25
- Scott. Spinal cord protection in aortic endovascular surgery. Br J Anaesth 2016;117:ii26-ii31
- Yang. Vascular surgery-related organ injury and protective strategies: update and future prospects. Br J Anaesth 2016;117:ii32-ii43
- Xia. Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans. Br J Anaesth 2016;117:ii44-ii62
- Wong. Contrast induced nephropathy in vascular surgery. Br J Anaesth 2016;117:ii63-ii73
- Koenig-Oberhuber. New antiplatelet drugs and new oral anticoagulants. Br J Anaesth 2016;117:ii74-ii84
- Chee. Management of bleeding in vascular surgery. Br J Anaesth 2016;117:ii85-ii94
- Seretny. Pain management in patients with vascular disease. Br J Anaesth 2016;117:ii95-ii106
- Ostermann. Patient Selection and Timing of Continuous Renal Replacement Therapy. Blood Purif 2016;42:224-237
- Bagshaw. Precision Continuous Renal Replacement Therapy and Solute Control. Blood Purif 2016;42:238-247
- Cerdá. Role of Technology for the Management of AKI in Critically Ill Patients: From Adoptive Technology to Precision Continuous Renal Replacement Therapy. Blood Purif 2016;42:248-265
- Murugan. Precision Fluid Management in Continuous Renal Replacement Therapy. Blood Purif 2016;42:266-278
- ISBI Practice Guidelines for Burn Care. Burns 2016;42:953-1021
- Whitaker. The European Board of Anaesthesiology recommendations for safe medication practice: First update. European Journal of Anaesthesiology 2016;epublished August 19th
- Melloul. Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations. World J Surg 2016;epublished August 22nd
- Bohmer. The Hard Work of Health Care Transformation. N Engl J Med 2016;375:709-711
- Goddard. Lessons to Be Learned From the UK Junior Doctors’ Strike. JAMA 2016;epublished August 22nd
- Haldar. Contemporary social network sites: Relevance in anesthesiology teaching, training, and research. J Anaesthesiol Clin Pharmacol 2016;32:382-5
- Various. Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. N Engl J Med 2016; 375:801-803
- Kyo. Factors affecting biomarkers of endothelial and alveolar epithelial dysfunction. Intensive Care Med 2016;epublished August 17th
- Response: Yehya. Factors affecting biomarkers of endothelial and alveolar epithelial dysfunction: response to comments by Kyo et al. Intensive Care Med 2016;epublished August 17th
Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.
Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.
Following last year's massively successful event, the UK Intensive Care Society's State-of-the-Art Meeting is starting its build-up to 2016. The ICS completely changed its game in 2015, and relaunched SOA as a new beacon for forward-looking clinical content, open-access education, and medical social media. In keeping with the times, the podcasts and other materials from last year's meeting have been made open access.
This year the programme is looking even better, with topics ranging from the futuristic (space medicine, Formula 1 applied technology, Google Deepmind, and AI) through to the human, practical, and controversial (look out for the clinical scenarios, controversies, and the "From Ivory Tower to Desert Island" session). Speakers include Peter Brindley, Kevin Fong, Jack Iwashyna, Kath Maitland, Louise Rose, Mervyn Singer, and Jean-Louis Vincent among many others. It runs from Mon 5th - Wed 7th Dec, and I hope I'll see you there. Keep an eye on http://soa.ics.ac.uk for programme and registration, and meanwhile enjoy the comprehensive FOAM from last year.
The 1st World Sepsis Congress will take place completely online on September 8th and 9th, 2016, as a prelude and introduction to the fifth World Sepsis Day on September 13th, 2016. Participation is open to everyone with an internet connection and free of charge. In 13 distinctive sessions, over 70 speakers from over 20 countries will give 10-minute keynotes and presentations on the number one preventable cause of death worldwide: sepsis. After each talk, the speakers will answer live questions from the audience.
Highlights include the Opening Session, titled "Sepsis - A Global Health Threat", with German Minister Helge Braun, Marie-Paule Kieny, Assistant Director-General of the WHO, Achim Steiner, former Under-Secretary General UN and Director of UNEP, and Joe Kiani, Founder & CEO of the Patient Safety Movement Foundation. To read the full invitation letter from the program chairs, Simon Finfer and Konrad Reinhart, please click here.
(Image from Chensiyuan via Wikipedia)
This adult and paediatric ICM meeting is jointly organized by the Society of Intensive Care Medicine (SICM), Singapore and the Australia-New Zealand Intensive Care Society (ANZICS) and is scheduled for 20-24 April 2017 in Suntec Convention Centre, Singapore. It has grown from its humble beginnings in a small hospital venue to become one of the best ICM conference in the Asia-Pacific region. Past editions featured prominent speakers such as Jean Louis Vincent, Daniel De Backer, John J Marini, Rinaldo Bellomo amongst many others, and in this edition the list of distinguished international panel of speakers, program schedule and planned workshops look more impressive than ever. Beside the obvious educational benefits, this conference is also a great opportunity to experience the unique Singaporean culture, enjoy its famed gastronomy and visit its attractions.
Registration is yet to open so do subscribe to its newsletter at www.sg-anzics.com for updates.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week