Welcome to the 229th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. This week's Topic of the Week is thromboembolic conditions, starting with a paper on Portal Vein Thrombosis in tomorrow's Paper of the Day.
Today, along with some friends, I'm asking for some help! See the message below from Paul Young.
You are invited to participate in a survey designed to provide estimates of ‘pre-test probability’ that hypotheses for major ongoing trials in critically ill adults are correct. These probability estimates will then be used to aid our understanding of what the trial results mean when the trials are completed. We think that you will find the survey interesting to complete because it will provide some information about major ongoing trials in the field. We estimate that it will take you around 10 minutes to do. We want as many Critical Care Reviews subscribers as possible to respond to the survey.
In order to record the number of people who could complete the survey, we're asking you to register for the newsletter and complete it via this route.
Thanks for your help.
Elliott Ridgeon | Scott Aberegg | Rinaldo Bellomo | Rachel Varughese | Rob Mac Sweeney | Paul Young
- Abstract: Rehrer. A Randomized Controlled Noninferiority Trial of Single Dose of Oral Dexamethasone Versus 5 Days of Oral Prednisone in Acute Adult Asthma. Annals of Emergency Medicine 2016;Epublished
- Abstract: Bignami. Desmopressin after cardiac surgery in bleeding patients. A multicenter randomized trial. Acta Anaesthesiologica Scandinavica 2016;epublished April 27th
- Abstract: Moeller. How safe is gelatin? a systematic review and meta-analysis of gelatin-containing plasma expanders versus crystalloids and albumin. J Crit Care 2016;epublished April 22nd
- Full Text: Elke. Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials. Critical Care 2016 20:117
- Abstract: Kurmis. Trace Element Supplementation Following Severe Burn Injury: A Systematic Review and Meta-Analysis. Journal of Burn Care & Research 2016;37(3):143–159
- Abstract: Goyal. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387(10029):1723–1731
- Abstract: Jensen. Comparing efficacy and safety of fibrinogen concentrate to cryoprecipitate in bleeding patients: a systematic review. Acta Anaesthesiologica Scandinavica 2016;epublished April 24th
- Abstract: Brodsky. Screening accuracy for aspiration using bedside water swallow tests: A systematic review and meta-analysis. Chest 2016;epublished April 28th
- Abstract: Scales. Improving Appropriate Neurological Prognostication After Cardiac Arrest: A Stepped Wedge Cluster RCT. Am J Respir Crit Care Med 2016;epublished April 26th
- Full Text: Norberg. Leakage of albumin in major abdominal surgery. Critical Care 2016;20:113
- Abstract: Ning. Platelet Transfusion Practices in the Intensive Care Unit: Data from a Large Transfusion Registry. Chest 2016;epublished April 29th
- Abstract: Self. Procalcitonin as an Early Marker of the Need for Invasive Respiratory or Vasopressor Support in Adults with Community-Acquired Pneumonia. Chest 2016;epublished April 20th
- Abstract: Giuliano. Comparison of Pediatric Severe Sepsis Managed in U.S. and European ICUs. Pediatr Crit Care Med 2016;epublished April 27th
- Abstract: Alhurani. Refractory Hypoxemia and Use of Rescue Strategies: A United States National Survey of Adult Intensivists. Annals ATS 2016;epublished April 29th
- Full Text: Delannoy. Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study. Crit Care Res Pract 2016;2016:7162190
- Full Text: Bardon. Reactive oxygen species measure for rapid detection of infection in fluids. Annals of Intensive Care 2016;6:41
- Krag. Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial (SUP-ICU). Trials 2016;17:205
- Dickstein. Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol. BMJ Open 2016;6(4):e009956
- Uchino. Brain injury following cardiac arrest: pathophysiology for neurocritical care. Journal of Intensive Care 2016;4:31
- Fukuda. Targeted temperature management for adult out-of-hospital cardiac arrest: current concepts and clinical applications. Journal of Intensive Care 2016;4:30
- Kinoshita. Traumatic brain injury: pathophysiology for neurocritical care. Journal of Intensive Care 2016;4:29
- Yokobori. Targeted temperature management in traumatic brain injury. Journal of Intensive Care 2016;4:28
- Dalle Ave. Using the brain criterion in organ donation after the circulatory determination of death. J Crit Care 2016;33:114–118
- Zheng. Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage. Cerebrovasc Dis 2016;42:155-169
- Manning. Endovascular Stroke Management: Key Elements of Success. Cerebrovasc Dis 2016;42:170-177
- Polewczyk. Cardiac device infections: definition, classification, differential diagnosis, and management. Pol Arch Med Wewn 2016;126(4):275-283
- Konstantinou. Digoxin in Heart Failure with a Reduced Ejection Fraction: A Risk Factor or a Risk Marker. Cardiology 2016;134:311-319
- Barbosaa. Is there any benefit in associating neuraxial anesthesia to general anesthesia for coronary artery bypass graft surgery? Brazilian Journal of Anesthesiology 2016;66(3):304–309
- Reichlina. Advanced ECG in 2016: is there more than just a tracing? Swiss Med Wkly 2016;146:w14303
- Mahan. Gravenstein: Long-axis view for ultrasound-guided central venous catheter placement via the internal jugular vein. Romanian Journal of Anaesthesia and Intensive Care 2016;23(1):27-31
- Hendy. Pulse waveform hemodynamic monitoring devices: recent advances and the place in goal-directed therapy in cardiac surgical patients. Romanian Journal of Anaesthesia and Intensive Care 2016;23(1):55-65
- Roca. Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure. Critical Care 2016;20:109
- Khetarpal. Regional anesthesia in difficult airway: The quest for a solution continues. Anesth Essays Res 2016;10:178-83
- Salih. Airway foreign bodies: A critical review for a common pediatric emergency. World J Emerg Med 2016;7(1):5–12
- Taniguchi. Acute and subacute idiopathic interstitial pneumonias. Respirology 2016;epublished April 28th
- Grottke. Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation. Critical Care 2016;20:115
- Pomara. A Pathophysiological Insight into Sepsis and Its Correlation with Postmortem Diagnosis. Mediators of Inflammation 2016;2016:4062829
- Bodolea. Anaesthesia in early childhood – is the development of the immature brain in danger? Romanian Journal of Anaesthesia and Intensive Care 2016;23(1):33-40
- Díaz-Gómez. Focused cardiac and lung ultrasonography: implications and applicability in the perioperative period. Romanian Journal of Anaesthesia and Intensive Care 2016;23(1):41-54
- Misal. Delayed recovery from anesthesia: A postgraduate educational review. Anesth Essays Res 2016;10:164-72
- Villar. The LUNG SAFE: a biased presentation of the prevalence of ARDS! Crit Care 2016;20(1):108
- Thiery. Zika virus-associated Guillain–Barré syndrome: a warning for critical care physicians. Intensive Care Med 2016;epublished April 27th
- Yau. Choice of crystalloids in sepsis: a conundrum waiting to be solved. Ann Transl Med 2016;4(6):121
- Szawarski. Classic cases revisited: Oscar the cat and predicting death. JICS 2016;epublished April 25th
- Martin. Singularity now: using the ventricular assist device as a model for future humanrobotic physiology. Romanian Journal of Anaesthesia and Intensive Care 2016;23(1):77-81
- Anonymous. 3D Printing in Transplantation. American Journal of Transplantation 2016;16:1339–1340
The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.
A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day. Book before 1st May to avail of the Early Bird option of €30 (limited availability).
Please contact Louise at email@example.com to register for the meeting and meal.
The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. Registration hasn't yet opened, but the meeting programme is available here.
The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week