Newsletter 220 | February 28th 2016
Welcome to the 220th Critical Care Reviews Newsletter, bringing you the most important research and open access articles from the past seven days. The highlights from the literature this week are the new Sepsis Definition (which was spoken about by Clifford Deutschmann at #CCR15) and LUNGSAFE, a large multicentre observational study documenting the epidemiology of ARDS.
Speaking of the Critical Care Reviews Meeting, the first talk from #CCR16 is now available, featuring Paul Young discussing his SPLIT trial, including the presentation of new, unpublished data and the first description of the massive #PLUStrial. Next up is John Holcomb and his mega trial PROPPR, which will be out later this week. To view these talks, please adjust your video player settings to HD, as Vimeo has made a strange change to it's default setting, resulting in the video often playing at low resolution. All videos from previous Critical Care Reviews Meetings are available to view here. Podcasts of these videos are in production.
Paul Young: Saline or Plasmalyte - Is SPLIT the Solution?
- Full Text: Billings. High-Dose Perioperative Atorvastatin and Acute Kidney Injury Following Cardiac SurgeryA Randomized Clinical Trial. AMA 2016;epublished February 23rd
- Abstract: Ishigaki. Saline Flush After Rocuronium Bolus Reduces Onset Time and Prolongs Duration of Effect: A Randomized Clinical Trial. Anesthesia & Analgesia 2016;122(3):706-711
- Abstract: Weinberg. Sodium bicarbonate infusion in patients undergoing orthotopic liver transplantation: a single centre randomized controlled pilot trial. Clinical Transplantation 2016;epublished February 23rd
- Abstract: Boyer. Terlipressin plus albumin is more effective than albumin alone in improving renal function in patients with cirrhosis and hepatorenal syndrome type 1. Gastroenterology 2016;epublished February 16th
- Full Text: Evaniew. Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Systematic Review and Meta-Analysis. J Neurotrauma 2016;33:468–481
- Full Text: Cardinal-Fernández. The presence of diffuse alveolar damage on open lung biopsy is associated with mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis. Chest 2016;epublished February 25th
- Full Text: Bellani. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA 2016;315(8):788-800
- Full Text: Halmin. Epidemiology of Massive Transfusion: A Binational Study From Sweden and Denmark. Crit Care Med 2016;44(3):468–477
- Full Text: Al-Ajlan. Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial. Stroke 2016;epublished February 18th
- Full Text: Berendt. From protocol to published report: a study of consistency in the reporting of academic drug trials. Trials 2016;17:100
- Abstract: Davenport. Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study. Lancet Respir Med 2016;epublished February 22nd
- Lundorf. Perioperative dexmedetomidine for acute pain after abdominal surgery in adults. Cochrane Database of Systematic Reviews 2016, Issue 2. Art. No.: CD010358
- Singer. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315(8):801-810
- Seymor. Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315(8):762-774
- Shankar-Hari. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315(8):775-787
- Dandel. Myocardial recovery during mechanical circulatory support: weaning and explantation criteria. Heart, Lung and Vessels 2015;7(4):280-288
- Nolan. Resuscitation highlights in 2015. Resuscitation 2016;100:A1–A8
- El-Tahan. Videolaryngoscopes for placement of double lumen tubes: Is it time to say goodbye to direct view?. Saudi J Anaesth 2016;10:218-27
- Maniwa. Surgical treatment of air way disease. J Thorac Dis 2016;8(1):E78–E82
- Mărginean. Anti-platelet Therapy Resistance – Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities. The Journal of Critical Care Medicine 2016;2(1):6-15
- Schmiedel. Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia. Swiss Med Wkly. 2016;146:w14281
- Angus. A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria. Crit Care Med 2016;44(3):e113–e121
- Seymour. Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria. Crit Care Med 2016;44(3):e122–e130
- Chertow. Critical Care Medicine After the 2014–2015 Ebola Outbreak: Are We Ready If It Happens Again? Crit Care Med 2016;44(3):457–459
- Frieri. Biomarkers, Trauma, and Sepsis in Pediatrics: A Review. J Pediatr Rev 2016;epublished January 26th
- Barbas. New puzzles for the use of non-invasive ventilation for immunosuppressed patients. J Thorac Dis 2016;8(1):E100–E103
- Poucke. Acetaminophen in critically ill patients, a therapy in search for big data analytics. J Thorac Dis 2016;8(1):E109–E110
- Makino. Acetaminophen for febrile patients with suspected infection: potential benefit and further directions. J Thorac Dis 2016;8(1):E111–E114
- Barbero. When clinical experiences clashes against evidence based medicine: the case of aspiration thrombectomy in primary percutaneous coronary intervention (PCI). J Thorac Dis 2016;8(1):E115–E117
- Inaba. Continuous or interrupted chest compressions for EMS-performed cardiopulmonary resuscitation. J Thorac Dis 2016;8(1):E118–E120
- Aramendi. To interrupt, or not to interrupt chest compressions for ventilation: that is the question! J Thorac Dis 2016;8(1):E121–E123
- Naumann. Venous-to-arterial CO2 differences and the quest for bedside point-of-care monitoring to assess the microcirculation during shock. Ann Transl Med 2016;4(2):37
- Scott. The impact of sedation protocols on outcomes in critical illness. Ann Transl Med 2016;4(2):33
- Barnes. Sedative choice and ventilator-associated patient outcomes: don’t sleep on delirium. Ann Transl Med 2016;4(2):34
- Righy. The best sedation drug—a quest for the holy grail? Ann Transl Med 2016;4(2):35
- Joshi. The Role of Ketamine in Low- and Middle-Income Countries: What Would Happen if Ketamine Becomes a Scheduled Drug? Anesthesia & Analgesia 2016;122(3):908-910
Although SMACCDUB sold out in less than 24 hours over three separate releases, there are still ways to get there. You can enter the SMACC BYTE competition. Summarise your favourite SMACC talk in a single slide or infographic and be in to win. Check out these examples. Entries close on close on Thursday, 10 March 2016 and the winners will be announced soon after on St. Patrick’s Day.
Failing that, you can enter the auction for two SMACC DUB ‘Golden Tickets‘. The winners will be true SMACC VIPs, with deluxe front row armchair seats, a personal butler, tickets to the speakers dinner, a chance to hangout with their favourite speaker and special SMACC packs. All proceeds will be donated to Focus Ireland, a charity tackling homelessness in Ireland. The auction starts 9am AEST 4th March and ends 9am AEST 9th March 2016.
(Image from Wikimedia)
The 13th Annual Critical Care Symposium is on April 28th and 29th in Manchester Town Hall, England. This meeting aims to bring together world renowned speakers for a conference outside London and to provide a conducive environment allowing informal discussion. Most importantly, this event provides good quality education covering various topics in Intensive Care at an affordable price.
The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.
The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. Registration hasn't yet opened, but the meeting programme is available here.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week