Newsletter 155 / November 23rd 2014
Welcome to the 155th Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals. There are no standout articles this week, with the highlights being the PARAMEDIC study, investigating the LUCAS-2 mechanical chest compression device during CPR, several papers on Ebola virus disease, acute pancreatitis and stroke. If you're a runner, you can find out whether this past-time is actually good for your heart or not.
This week's Topic of the Week is Lung Ultrasound, starting with a paper on the sonographic diagnosis of pneumothorax in tomorrow's Paper of the Day.
Critical Care Reviews Meeting 2015
It's just 9 weeks until the 2015 Critical Care Reviews Meeting, being held in association with the Northern Ireland Intensive Care Society. This not-for-profit event will be held on Friday January 23rd, at the Galgorm Resort and Spa, outside Belfast, Northern Ireland. The event theme is to review the hottest trials of 2014, aiming to decide whether we should implement the results of these studies. On hand to provide genuine expert opinion will be the chief investigators for several of these trials, including TTM, VITdAL-ICU, CALORIES, ProMISe and HARP-2. In addition, another 8 major randomized controlled trials will be critiqued. Further talks include early mobilisation, ECMO, airway management, and neuroprognostication post cardiac arrest. Amazingly, if the embargo has lifted in time, we will also have the inside line on, and be one of the first worldwide to discuss, the new sepsis definitions. With chief investigators for three of the major RCTs presented at ESICM just last month, the chief investigator for the biggest critical care study of 2013, and the chief investigator for the third of the 2014 early goal-directed therapy sepsis studies, it's one of the most contemporary, focused meetings around - you won't want to miss it.
The impressive list of speakers includes Clifford Deutschman (USA), past president of the Society of Critical Care Medicine, Niklas Nielsen (Sweden), Eddy Fan (Canada), Kathy Rowan (England), Karin Amrein, (Austria), Danny McAuley and Eamon McCoy (Northern Ireland), plus a host of local intensivists. In keeping with a FOAMed event, this is a not-for-profit meeting, with all talks being recorded and made freely available online shortly after.
If you're a drive or short flight away, it would be great to have you come along. Travel on Thursday, attend the meeting on Friday and see some of the local landmarks over the weekend, before returning home on Sunday evening after a great winter break. On Saturday visit the North Coast: the World Heritage site Giants Causeway, Carrick-a-Rede rope bridge, Dunluce Castle and Bushmills Distillary, the oldest distillary in the world; while on Sunday experience Belfast: the new acclaimed Titanic Centre followed by a famous black taxi tour describing the troubled past of one of Europe's now most vibrant cities. The Galgorm Resort and Spa is one of Northern Ireland's premier hotels and is a 30 minute drive from Belfast International Airport.
Online registration is open and the programme is available as a download, with further information at the meeting webpage. As capacity is limited, don't wait to book your place and potentially miss out. Please feel free to contact me if you're thinking about making the trip - it would be great to hear from you.
The next SMACC conference will be held June 23rd to 26th, in Chicago, USA. Just like the Critical Care Reviews Meeting, this is a not-for-profit event, run by a team interested in sharing knowledge in a fun, modern way. It's a conference like no other. The amazing programme and registration are available on the SMACC website.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. A call for papers has been issued, so if you have something interesting to say, and can say it in an engaging manner, please get in touch. The first issue will be released on January 1st 2015.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
Randomized Controlled Trials
- Full Text: Perkins. Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial. Lancet 2014;epublished November 16th
- Full Text: Mauri. Dual Antiplatelet Therapy after Drug-Eluting Stents (DAPT Study). N Engl J Med 2014;epublished November 16th
- Abstract: Bakker. Early versus On-Demand Nasoenteric Tube Feeding in Acute Pancreatitis. N Engl J Med 2014; 371:1983-1993
- Abstract: Song. Double-blinded, randomised controlled trial of N-acetylcysteine for prevention of acute kidney injury in high risk patients undergoing off-pump coronary artery bypass. Nephrology 2014;epublished November 11th
- Abstract: Rasmussen. Effects of Prostacyclin on Cerebral Blood Flow and Vasospasm After Subarachnoid Hemorrhage. Randomized, Pilot Trial. Stroke 2014;epublished November 20th
- Abstract: de Almeida. Transfusion Requirements in Surgical Oncology Patients: A Prospective, Randomized Controlled Trial. Anesthesiology 2014;epublished November 14th
Meta Analyses
- Abstract: de Jager. Tidal Volume and Mortality in Mechanically Ventilated Children: A Systematic Review and Meta-Analysis of Observational Studies. Critical Care Med 2014;42(12):2461–2472
- Abstract: Curley. Transfusion Triggers for Guiding RBC Transfusion for Cardiovascular Surgery: A Systematic Review and Meta-Analysis. Critical Care Med 2014;42(12):611–2624
- Abstract: Rodrigo. Effect of corticosteroid therapy on influenza-related mortality: a systematic review and meta-analysis. J Infect Dis 2014;epublished November 18th
- Full Text: Kumar. Platelet transfusion: a systematic review of the clinical evidence. Transfusion 2014;epublished November 12th
- Abstract: Sheyin. The prognostic significance of troponin elevation in patients with sepsis: A meta-analysis. Heart & Lung: The Journal of Acute and Critical Care 2014;epublished November 18th
Observational Studies
- Abstract: Nadeem. Chloride-liberal fluids are associated with acute kidney injury after liver transplantation. Crit Care 2014;18(6):625
- Abstract: Silversides. Fluid balance, intradialytic hypotension, and outcomes in critically ill patients undergoing renal replacement therapy: a cohort study. Crit Care 2014;epublished 2014;18(6):624
- Abstract: Lewnard. Dynamics and control of Ebola virus transmission in Montserrado, Liberia: a mathematical modelling analysis. Lancet Infectious Diseases 2014;14(12):1189-1195
- Abstract: Zilberberg. Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: A retrospective cohort study. Critical Care 2014;18:596
- Abstract: Dankiewicz. Safety, Feasibility, and Outcomes of Induced Hypothermia Therapy Following In-Hospital Cardiac Arrest—Evaluation of a Large Prospective Registry. Critical Care Med 2014;42(12):2537–2545
- Abstract: Lin. Targeted Temperature Management Processes and Outcomes After Out-of-Hospital Cardiac Arrest: An Observational Cohort Study. Critical Care Med 2014;42(12):2565–2574
- Abstract: Mulder. Awakening and Withdrawal of Life-Sustaining Treatment in Cardiac Arrest Survivors Treated With Therapeutic Hypothermia. Critical Care Med 2014;42(12):2493–2499
- Abstract: Debiane. The Utility of Proadrenomedullin and Procalcitonin in Comparison to C-Reactive Protein as Predictors of Sepsis and Bloodstream Infections in Critically Ill Patients With Cancer. Critical Care Med 2014;42(12):2500-2507
- Abstract: Jordan. Adrenomedullin is a useful biomarker for the prognosis of critically ill septic children. Biomark Med 2014;8(9):1065-72
- Abstract: Karsies. An empiric antibiotic protocol using risk stratification improves antibiotic selection and timing in critically ill children. Annals ATS 2014;epublished November 17th
- Full Text: Wong. Trends in Short and Long-Term Survival Among Out-of-Hospital Cardiac Arrest Patients Alive at Hospital Arrival. Circulation 2014;epublished November 15th
- Full Text: Chan. Recent Trends in Survival from Out-of-Hospital Cardiac Arrest in the United States. Circulation 2014;epublished November 15th
- Full Text: Blom. Improved Survival After Out-of-Hospital Cardiac Arrest and Use of Automated External Defibrillators. Circulation 2014;epublished November 15th
- Abstract: Lund. Association Between Use of β-Blockers and Outcomes in Patients With Heart Failure and Preserved Ejection Fraction. JAMA 2014;312(19):2008-2018
- Full Text: Frenette. Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis. Critical Care 2014;18:602
Editorials
Clinical
- Xanthos. ‘Do not attempt cardiopulmonary resuscitation’ or ‘allowing natural death’? The time for resuscitation community to review its boundaries and its terminology. Resuscitation 2014;85(11):1644-1645
- Ronco. AKI Biomarkers www (Who, Where, When): You Cannot Treat What You Do Not Know. Blood Purif 2014;38:I-II
- Murthy. Cerebral venous thrombosis: Endovascular therapy. Neurol India 2014;62:485-6
- Bertini. New applications in cardiac anaesthesiology: portable technology improves echocardiography reporting. Egypt J Cardiothorac Anesth 2014;8:57-8
- Imazio. Pericardial decompression syndrome: A rare but potentially fatal complication of pericardial drainage to be recognized and prevented. European Heart Journal: Acute Cardiovascular Care 2014;epublished November 18th
Non-Clinical
Commentaries
Clinical
- Bellizzi. The current Ebola outbreak: old and new contexts. J Infect Dev Ctries 2014;8(11):1378-1380
Non-Clinical
- Gostin. The President’s National Security Agenda: Curtailing Ebola, Safeguarding the Future. JAMA 2014;epublished November 20th
- The Lancet Infectious Diseases. Rationality and coordination for Ebola outbreak in west Africa. Lancet Infectious Diseases 2014;14(12):1163
- Anonymous. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. J Korean Med Assoc 2014;57(11):899-902
- Hudson. Sharing and Reporting the Results of Clinical Trials. JAMA 2014;epublished November 19th
Case Reports
- Parra. The First Case of Ebola Virus Disease Acquired outside Africa. N Engl J Med 2014;epublished November 19th
- Choi. Application of veno-arterial-venous extracorporeal membrane oxygenation in differential hypoxia. Multidisciplinary Respiratory Medicine 2014;9:55
News
- McCarthy. Surgeon from Sierra Leone treated for Ebola in Nebraska dies. BMJ 2014;349:g6942
- CDC. Update: Ebola Virus Disease Epidemic — West Africa, November 2014 - Early Release. CDC 2014;epublished November 18th
Clinical Review Articles
- Goldstein. Modern Medical Management of Acute Ischemic Stroke. Methodist Debakey Cardiovasc J 2014;10(2):99–104
- Ferrell. Modern Interventional Management of Stroke. Methodist Debakey Cardiovasc J 2014;10(2):105–110
- Kozar. Hyperperfusion and intracranial haemorrhage after carotid angioplasty with stenting – latest review. SIGNA VITAE 2014;9(2):9-14
- Lu. Emerging MRI and metabolic neuroimaging techniques in mild traumatic brain injury. Neurol India 2014;62:487-91
- Corbett. How Can You Mend a Broken Brain - Neurorestorative Approaches to Stroke Recovery. Cerebrovasc Dis 2014;38:233-239
- Varvarousi. Glucocorticoids as an Emerging Pharmacologic Agent for Cardiopulmonary Resuscitation. Cardiovasc Drugs Ther 2014;28:477–488
- Kumar. Device Therapies: New Indications and Future Directions. Current Cardiology Reviews 2015;11:33-41
- Oktay. Diagnosis and Management of Heart Failure with Preserved Ejection Fraction: 10 Key Lessons. Current Cardiology Reviews 2015;11:42-52
- Kahn. Evolution of Artificial Hearts: An Overview and History. Cardiol Res 2014;5(5):121-125
- Jung. Percutaneous left ventricular assist device: a systematic review. J Korean Med Assoc 2014;57(11):949-956
- Möckel. Copeptin—Marker of Acute Myocardial Infarction. Curr Atheroscler Rep 2014;16:421
- Hanna. Acute Heart Failure: Acute Cardiorenal Syndrome and Role of Aggressive Decongestion. Clin Cardiol 2014;epublished November 17th
- Sharma. Role of Oral Factor Xa Inhibitors after Acute Coronary Syndrome. Cardiology 2014;129:224-232
- Longrois. Sedation in non-invasive ventilation: do we know what to do (and why)? Multidisciplinary Respiratory Medicine 2014;9:56
- Islam. The Diagnosis of Acute Pulmonary Embolism. SWRCCC 2014;2(8):21-30
- Navarrete-Opazo. Therapeutic potential of intermittent hypoxia: a matter of dose. Am J Physiol Regul Integr Comp Physiol 2014;307:R1181–R1197
- Spangler. Abdominal emergencies in the geriatric patient. International Journal of Emergency Medicine 2014;7:43
- Kokosis. Surgical management of necrotizing pancreatitis: An overview. World J Gastroenterol 2014;20(43):16106-16112
- Hegazi. Enteral nutrition and immune modulation of acute pancreatitis. World J Gastroenterol 20(43):16101-16105
- Bortolotti. New tools for optimizing fluid resuscitation in acute pancreatitis. World J Gastroenterol 20(43):16113-16122
- Oláh. Enteral nutrition in acute pancreatitis: A review of the current evidence. World J Gastroenterol 20(43):16123-16131
- Hung. Contemporary review of drug-induced pancreatitis: A different perspective. World J Gastrointest Pathophysiol 2014;5(4):405-415
- Kim. Diagnosis of gastrointestinal bleeding: A practical guide for clinicians. World J Gastrointest Pathophysiol 2014;5(4):467-478
- Goeijenbier. Ebola virus disease: a review on epidemiology, symptoms, treatment and pathogenesis. Nethlands Journal of Medicine 2014;72(9):442-448
- Kalra. The emergence of Ebola as a global health security threat: From 'lessons learned' to coordinated multilateral containment efforts. J Global Infect Dis 2014;6:164-77
- Liu. Systematic review of severe fever with thrombocytopenia syndrome:virology, epidemiology, and clinical characteristics. Rev. Med. Virol 2014;24:90–102
- Zingg. Hospital organisation, management, and structure for prevention of health-care-associated infection: a systematic review and expert consensus. Lancet Infectious Diseases 2014;epublished November 11th
- Barroga. Safeguarding the Integrity of Science Communication by Restraining 'Rational Cheating' in Peer Review. J Korean Med Sci 2014;29(11):1450-1452
Until next week